Mortality and health-related quality of life in patients surgically treated for spondylodiscitis
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Mortality and health-related quality of life in patients surgically treated for spondylodiscitis. / Dragsted, Casper; Aagaard, Theis; Ohrt-Nissen, Søren; Gehrchen, Martin; Dahl, Benny.
I: Journal of Orthopaedic Surgery, Bind 25, Nr. 2, 2309499017716068, 2017.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Mortality and health-related quality of life in patients surgically treated for spondylodiscitis
AU - Dragsted, Casper
AU - Aagaard, Theis
AU - Ohrt-Nissen, Søren
AU - Gehrchen, Martin
AU - Dahl, Benny
PY - 2017
Y1 - 2017
N2 - PURPOSE: To assess mortality, disability, and health-related quality of life (HRQL) in patients surgically treated for spondylodiscitis.METHODS: A retrospective longitudinal study was conducted on all patients surgically treated for spondylodiscitis over a 6-year period at a single tertiary spine center. Indications for surgery, pre- and postoperative neurological impairment, comorbidities, and mortality were recorded. A survey was conducted on all eligible patients with the EuroQol 5-dimension (EQ-5D) questionnaire and Oswestry Disability Index (ODI).RESULTS: Sixty-five patients were diagnosed with spondylodiscitis not related to recent spine surgery. One-year mortality rate was 6%. In all, 36% and 27% had pre- and postoperative neurological impairment, respectively, with only one patient experiencing deterioration postoperatively. At final follow-up (median 2 years), mean ODI was 31% (SD = 22) and mean EQ-5D time trade-off score was 0.639 (SD = 0.262); this was significantly lower than that in the normal population ( p < 0.001). Patients with neurological impairment prior to index surgery had lower EQ-5D scores ( p = 0.005) and higher ODI ( p = 0.02) at final follow-up compared with patients without neurological impairment.CONCLUSIONS: Several years after surgery, patients surgically treated for spondylodiscitis have significantly lower HRQL and more disability than the background population. Neurological impairment prior to index surgery predicts adverse outcome in terms of disability and lower HRQL.
AB - PURPOSE: To assess mortality, disability, and health-related quality of life (HRQL) in patients surgically treated for spondylodiscitis.METHODS: A retrospective longitudinal study was conducted on all patients surgically treated for spondylodiscitis over a 6-year period at a single tertiary spine center. Indications for surgery, pre- and postoperative neurological impairment, comorbidities, and mortality were recorded. A survey was conducted on all eligible patients with the EuroQol 5-dimension (EQ-5D) questionnaire and Oswestry Disability Index (ODI).RESULTS: Sixty-five patients were diagnosed with spondylodiscitis not related to recent spine surgery. One-year mortality rate was 6%. In all, 36% and 27% had pre- and postoperative neurological impairment, respectively, with only one patient experiencing deterioration postoperatively. At final follow-up (median 2 years), mean ODI was 31% (SD = 22) and mean EQ-5D time trade-off score was 0.639 (SD = 0.262); this was significantly lower than that in the normal population ( p < 0.001). Patients with neurological impairment prior to index surgery had lower EQ-5D scores ( p = 0.005) and higher ODI ( p = 0.02) at final follow-up compared with patients without neurological impairment.CONCLUSIONS: Several years after surgery, patients surgically treated for spondylodiscitis have significantly lower HRQL and more disability than the background population. Neurological impairment prior to index surgery predicts adverse outcome in terms of disability and lower HRQL.
KW - Aged
KW - Decompression, Surgical
KW - Disability Evaluation
KW - Discitis/microbiology
KW - Female
KW - Health Care Surveys
KW - Humans
KW - Longitudinal Studies
KW - Male
KW - Middle Aged
KW - Orthopedic Procedures
KW - Quality of Life
KW - Retrospective Studies
KW - Spine/microbiology
KW - Treatment Outcome
U2 - 10.1177/2309499017716068
DO - 10.1177/2309499017716068
M3 - Journal article
C2 - 28639530
VL - 25
JO - Journal of Orthopaedic Surgery
JF - Journal of Orthopaedic Surgery
SN - 1022-5536
IS - 2
M1 - 2309499017716068
ER -
ID: 195005565