Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Recently, it has been shown that a homozygous 32 base-pair deletion in the gene encoding CKR-5, a major coreceptor for HIV-1, leads to resistance to infection with HIV-1. We have investigated whether HIV-seropositive individuals who were heterozygous for the CKR-5 deletion had a different course of the disease.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | AIDS |
| Vol/bind | 11 |
| Udgave nummer | 3 |
| Sider (fra-til) | 305-10 |
| Antal sider | 6 |
| ISSN | 0269-9370 |
| Status | Udgivet - 1997 |
ID: 40148459