Indocyanine green angiography in oncoplastic breast surgery, a prospective study
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Indocyanine green angiography in oncoplastic breast surgery, a prospective study. / Lauritzen, Elisabeth; Bredgaard, Rikke; Laustsen-Kiel, Cecilie Mullerup; Hansen, Laura; Tvedskov, Tove; Damsgaard, Tine Engberg.
I: Journal of Plastic, Reconstructive and Aesthetic Surgery, Bind 85, 2023, s. 276-286.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Indocyanine green angiography in oncoplastic breast surgery, a prospective study
AU - Lauritzen, Elisabeth
AU - Bredgaard, Rikke
AU - Laustsen-Kiel, Cecilie Mullerup
AU - Hansen, Laura
AU - Tvedskov, Tove
AU - Damsgaard, Tine Engberg
N1 - Publisher Copyright: © 2023 British Association of Plastic, Reconstructive and Aesthetic Surgeons
PY - 2023
Y1 - 2023
N2 - Introduction: The use of Indocyanine green angiography (ICG-A) in oncoplastic breast-conserving surgery (OBCS) has not yet been investigated. This prospective trial applied ICG-A in volume displacement and replacement OBCS to localize perforators and determine tissue supplied by the perforator. Furthermore, to investigate and correlate the intraoperative ICG-A to postoperative surgical site infection, skin necrosis, epidermolysis, and timely onset of adjuvant therapy. Methods: ICG-A was performed at three pre-set timepoints during surgery; after lumpectomy, upon dissection of possible perforators, and after wound closure. All patients were followed with clinical evaluations before surgery, 4 weeks, 4–6 months, and 12 months postoperatively. Results: Eleven patients were included: seven volume displacement and four volume replacement OBCS. ICG-A located the tissue supplied by the perforator and demonstrated sufficient perfusion in all cases. The ICG-A corresponded to the surgeons’ clinical assessment. One patient developed a postoperative infection and seroma and was treated conservatively. No patients had postoperative necrosis, loss of reconstruction, or lymphedema of the arm. Edema of the breast occurred in four patients (36.4%). Scar assessments were significantly worse at 4-weeks and 4–6 months. The quality of life improved significantly during follow-up. Adjuvant treatment was administered timely in all cases. Conclusion: ICG-A was feasible for OBCS in assessing intraoperative perfusion. Perfusion was sufficient in all patients and corresponded to the surgeon's clinical evaluation. No patients developed postoperative necrosis. Though edema of the breast occurred in 36.4%, a larger sample size is needed to investigate a possible correlation with ICG-A. Further studies, which includes patients requiring extensive tissue replacement challenging the borders of perfusion, are needed.
AB - Introduction: The use of Indocyanine green angiography (ICG-A) in oncoplastic breast-conserving surgery (OBCS) has not yet been investigated. This prospective trial applied ICG-A in volume displacement and replacement OBCS to localize perforators and determine tissue supplied by the perforator. Furthermore, to investigate and correlate the intraoperative ICG-A to postoperative surgical site infection, skin necrosis, epidermolysis, and timely onset of adjuvant therapy. Methods: ICG-A was performed at three pre-set timepoints during surgery; after lumpectomy, upon dissection of possible perforators, and after wound closure. All patients were followed with clinical evaluations before surgery, 4 weeks, 4–6 months, and 12 months postoperatively. Results: Eleven patients were included: seven volume displacement and four volume replacement OBCS. ICG-A located the tissue supplied by the perforator and demonstrated sufficient perfusion in all cases. The ICG-A corresponded to the surgeons’ clinical assessment. One patient developed a postoperative infection and seroma and was treated conservatively. No patients had postoperative necrosis, loss of reconstruction, or lymphedema of the arm. Edema of the breast occurred in four patients (36.4%). Scar assessments were significantly worse at 4-weeks and 4–6 months. The quality of life improved significantly during follow-up. Adjuvant treatment was administered timely in all cases. Conclusion: ICG-A was feasible for OBCS in assessing intraoperative perfusion. Perfusion was sufficient in all patients and corresponded to the surgeon's clinical evaluation. No patients developed postoperative necrosis. Though edema of the breast occurred in 36.4%, a larger sample size is needed to investigate a possible correlation with ICG-A. Further studies, which includes patients requiring extensive tissue replacement challenging the borders of perfusion, are needed.
KW - ICG-A
KW - Indocyanine green angiography
KW - Oncoplastic breast surgery
KW - Volume displacement
KW - Volume replacement
U2 - 10.1016/j.bjps.2023.07.022
DO - 10.1016/j.bjps.2023.07.022
M3 - Journal article
C2 - 37541044
AN - SCOPUS:85166525007
VL - 85
SP - 276
EP - 286
JO - Journal of plastic, reconstructive & aesthetic surgery : JPRAS
JF - Journal of plastic, reconstructive & aesthetic surgery : JPRAS
SN - 1748-6815
ER -
ID: 371922921