SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination

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SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination. / Castruita, Jose Alfredo Samaniego; Schneider, Uffe Vest; Mollerup, Sarah; Leineweber, Thomas Daell; Weis, Nina; Bukh, Jens; Pedersen, Martin Schou; Westh, Henrik.

I: APMIS, Bind 131, Nr. 3, 2023, s. 128-132.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Castruita, JAS, Schneider, UV, Mollerup, S, Leineweber, TD, Weis, N, Bukh, J, Pedersen, MS & Westh, H 2023, 'SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination', APMIS, bind 131, nr. 3, s. 128-132. https://doi.org/10.1111/apm.13294

APA

Castruita, J. A. S., Schneider, U. V., Mollerup, S., Leineweber, T. D., Weis, N., Bukh, J., Pedersen, M. S., & Westh, H. (2023). SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination. APMIS, 131(3), 128-132. https://doi.org/10.1111/apm.13294

Vancouver

Castruita JAS, Schneider UV, Mollerup S, Leineweber TD, Weis N, Bukh J o.a. SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination. APMIS. 2023;131(3):128-132. https://doi.org/10.1111/apm.13294

Author

Castruita, Jose Alfredo Samaniego ; Schneider, Uffe Vest ; Mollerup, Sarah ; Leineweber, Thomas Daell ; Weis, Nina ; Bukh, Jens ; Pedersen, Martin Schou ; Westh, Henrik. / SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination. I: APMIS. 2023 ; Bind 131, Nr. 3. s. 128-132.

Bibtex

@article{cd906ae0188b45d29c3d32fe6afd5be5,
title = "SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination",
abstract = "In Denmark, vaccination against Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) has been with the Pfizer-BioNTech (BTN162b2) or the Moderna (mRNA-1273) mRNA vaccines. Patients with chronic hepatitis C virus (HCV) infection followed in our clinic received mRNA vaccinations according to the Danish roll-out vaccination plan. To monitor HCV infection, RNA was extracted from patient plasma and RNA sequencing was performed on the Illumina platform. In 10 of 108 HCV patient samples, full-length or traces of SARS-CoV-2 spike mRNA vaccine sequences were found in blood up to 28 days after COVID-19 vaccination. Detection of mRNA vaccine sequences in blood after vaccination adds important knowledge regarding this technology and should lead to further research into the design of lipid-nanoparticles and the half-life of these and mRNA vaccines in humans.",
keywords = "blood, Hepatitis C virus, mRNA, SARS-CoV-2, vaccine",
author = "Castruita, {Jose Alfredo Samaniego} and Schneider, {Uffe Vest} and Sarah Mollerup and Leineweber, {Thomas Daell} and Nina Weis and Jens Bukh and Pedersen, {Martin Schou} and Henrik Westh",
note = "Publisher Copyright: {\textcopyright} 2023 The Authors. APMIS published by John Wiley & Sons Ltd on behalf of Scandinavian Societies for Pathology, Medical Microbiology and Immunology.",
year = "2023",
doi = "10.1111/apm.13294",
language = "English",
volume = "131",
pages = "128--132",
journal = "A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica",
issn = "0903-4641",
publisher = "Wiley Online",
number = "3",

}

RIS

TY - JOUR

T1 - SARS-CoV-2 spike mRNA vaccine sequences circulate in blood up to 28 days after COVID-19 vaccination

AU - Castruita, Jose Alfredo Samaniego

AU - Schneider, Uffe Vest

AU - Mollerup, Sarah

AU - Leineweber, Thomas Daell

AU - Weis, Nina

AU - Bukh, Jens

AU - Pedersen, Martin Schou

AU - Westh, Henrik

N1 - Publisher Copyright: © 2023 The Authors. APMIS published by John Wiley & Sons Ltd on behalf of Scandinavian Societies for Pathology, Medical Microbiology and Immunology.

PY - 2023

Y1 - 2023

N2 - In Denmark, vaccination against Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) has been with the Pfizer-BioNTech (BTN162b2) or the Moderna (mRNA-1273) mRNA vaccines. Patients with chronic hepatitis C virus (HCV) infection followed in our clinic received mRNA vaccinations according to the Danish roll-out vaccination plan. To monitor HCV infection, RNA was extracted from patient plasma and RNA sequencing was performed on the Illumina platform. In 10 of 108 HCV patient samples, full-length or traces of SARS-CoV-2 spike mRNA vaccine sequences were found in blood up to 28 days after COVID-19 vaccination. Detection of mRNA vaccine sequences in blood after vaccination adds important knowledge regarding this technology and should lead to further research into the design of lipid-nanoparticles and the half-life of these and mRNA vaccines in humans.

AB - In Denmark, vaccination against Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) has been with the Pfizer-BioNTech (BTN162b2) or the Moderna (mRNA-1273) mRNA vaccines. Patients with chronic hepatitis C virus (HCV) infection followed in our clinic received mRNA vaccinations according to the Danish roll-out vaccination plan. To monitor HCV infection, RNA was extracted from patient plasma and RNA sequencing was performed on the Illumina platform. In 10 of 108 HCV patient samples, full-length or traces of SARS-CoV-2 spike mRNA vaccine sequences were found in blood up to 28 days after COVID-19 vaccination. Detection of mRNA vaccine sequences in blood after vaccination adds important knowledge regarding this technology and should lead to further research into the design of lipid-nanoparticles and the half-life of these and mRNA vaccines in humans.

KW - blood

KW - Hepatitis C virus

KW - mRNA

KW - SARS-CoV-2

KW - vaccine

U2 - 10.1111/apm.13294

DO - 10.1111/apm.13294

M3 - Journal article

C2 - 36647776

AN - SCOPUS:85146942614

VL - 131

SP - 128

EP - 132

JO - A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica

JF - A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica

SN - 0903-4641

IS - 3

ER -

ID: 340112060