N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls

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Standard

N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls. / Krogh, Jesper; Ströhle, Andreas; Westrin, Asa; Klausen, Tobias; Jørgensen, Martin Balslev; Nordentoft, Merete.

I: Psychoneuroendocrinology, 2011, s. 656-63.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Krogh, J, Ströhle, A, Westrin, A, Klausen, T, Jørgensen, MB & Nordentoft, M 2011, 'N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls', Psychoneuroendocrinology, s. 656-63. https://doi.org/10.1016/j.psyneuen.2010.09.009

APA

Krogh, J., Ströhle, A., Westrin, A., Klausen, T., Jørgensen, M. B., & Nordentoft, M. (2011). N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls. Psychoneuroendocrinology, 656-63. https://doi.org/10.1016/j.psyneuen.2010.09.009

Vancouver

Krogh J, Ströhle A, Westrin A, Klausen T, Jørgensen MB, Nordentoft M. N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls. Psychoneuroendocrinology. 2011;656-63. https://doi.org/10.1016/j.psyneuen.2010.09.009

Author

Krogh, Jesper ; Ströhle, Andreas ; Westrin, Asa ; Klausen, Tobias ; Jørgensen, Martin Balslev ; Nordentoft, Merete. / N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls. I: Psychoneuroendocrinology. 2011 ; s. 656-63.

Bibtex

@article{a97d17352b734ff8b79f775184bd43f5,
title = "N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls",
abstract = "BACKGROUND: The dysfunction of hypothalamic-pituitary-adrenal (HPA) axis in major depression includes hyperactivity and reduced feedback inhibition. Atrial natriuretic peptide (ANP) is able to reduce the HPA-axis response to stress and has an anxiolytic effect in rodents and humans. We hypothesized that patients with depression would have an attenuated N-terminal proANP (NT-proANP) response to acute exercise compared to healthy controls. Secondly, we aimed to assess the effect of antidepressants on NT-proANP response to acute exercise. METHODS: We examined 132 outpatients with mild to moderate depression (ICD-10) and 44 healthy controls, group matched for age, sex, and BMI. We used an incremental bicycle ergometer test as a physical stressor. Blood samples were drawn at rest, at exhaustion, and 15, 30, and 60min post-exercise. RESULTS: The NT-proANP response to physical exercise differed between depressed subjects and healthy controls (group×time; F(4,162.9)=10.92; p",
author = "Jesper Krogh and Andreas Str{\"o}hle and Asa Westrin and Tobias Klausen and J{\o}rgensen, {Martin Balslev} and Merete Nordentoft",
note = "Copyright {\textcopyright} 2010 Elsevier Ltd. All rights reserved.",
year = "2011",
doi = "http://dx.doi.org/10.1016/j.psyneuen.2010.09.009",
language = "English",
pages = "656--63",
journal = "Psychoneuroendocrinology",
issn = "0306-4530",
publisher = "Pergamon Press",

}

RIS

TY - JOUR

T1 - N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls

AU - Krogh, Jesper

AU - Ströhle, Andreas

AU - Westrin, Asa

AU - Klausen, Tobias

AU - Jørgensen, Martin Balslev

AU - Nordentoft, Merete

N1 - Copyright © 2010 Elsevier Ltd. All rights reserved.

PY - 2011

Y1 - 2011

N2 - BACKGROUND: The dysfunction of hypothalamic-pituitary-adrenal (HPA) axis in major depression includes hyperactivity and reduced feedback inhibition. Atrial natriuretic peptide (ANP) is able to reduce the HPA-axis response to stress and has an anxiolytic effect in rodents and humans. We hypothesized that patients with depression would have an attenuated N-terminal proANP (NT-proANP) response to acute exercise compared to healthy controls. Secondly, we aimed to assess the effect of antidepressants on NT-proANP response to acute exercise. METHODS: We examined 132 outpatients with mild to moderate depression (ICD-10) and 44 healthy controls, group matched for age, sex, and BMI. We used an incremental bicycle ergometer test as a physical stressor. Blood samples were drawn at rest, at exhaustion, and 15, 30, and 60min post-exercise. RESULTS: The NT-proANP response to physical exercise differed between depressed subjects and healthy controls (group×time; F(4,162.9)=10.92; p

AB - BACKGROUND: The dysfunction of hypothalamic-pituitary-adrenal (HPA) axis in major depression includes hyperactivity and reduced feedback inhibition. Atrial natriuretic peptide (ANP) is able to reduce the HPA-axis response to stress and has an anxiolytic effect in rodents and humans. We hypothesized that patients with depression would have an attenuated N-terminal proANP (NT-proANP) response to acute exercise compared to healthy controls. Secondly, we aimed to assess the effect of antidepressants on NT-proANP response to acute exercise. METHODS: We examined 132 outpatients with mild to moderate depression (ICD-10) and 44 healthy controls, group matched for age, sex, and BMI. We used an incremental bicycle ergometer test as a physical stressor. Blood samples were drawn at rest, at exhaustion, and 15, 30, and 60min post-exercise. RESULTS: The NT-proANP response to physical exercise differed between depressed subjects and healthy controls (group×time; F(4,162.9)=10.92; p

U2 - http://dx.doi.org/10.1016/j.psyneuen.2010.09.009

DO - http://dx.doi.org/10.1016/j.psyneuen.2010.09.009

M3 - Journal article

SP - 656

EP - 663

JO - Psychoneuroendocrinology

JF - Psychoneuroendocrinology

SN - 0306-4530

ER -

ID: 34108253