Association between Type D personality and outcomes in patients with non-ischemic heart failure
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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Association between Type D personality and outcomes in patients with non-ischemic heart failure. / Bundgaard, Johan S; Østergaard, Lauge; Gislason, Gunnar; Thune, Jens J; Nielsen, Jens C; Haarbo, Jens; Videbæk, Lars; Olesen, Line L; Thøgersen, Anna M; Torp-Pedersen, Christian; Pedersen, Susanne S; Køber, Lars; Mogensen, Ulrik M.
I: Quality of Life Research, Bind 28, Nr. 11, 11.2019, s. 2901-2908.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Association between Type D personality and outcomes in patients with non-ischemic heart failure
AU - Bundgaard, Johan S
AU - Østergaard, Lauge
AU - Gislason, Gunnar
AU - Thune, Jens J
AU - Nielsen, Jens C
AU - Haarbo, Jens
AU - Videbæk, Lars
AU - Olesen, Line L
AU - Thøgersen, Anna M
AU - Torp-Pedersen, Christian
AU - Pedersen, Susanne S
AU - Køber, Lars
AU - Mogensen, Ulrik M
PY - 2019/11
Y1 - 2019/11
N2 - PURPOSE: The "distressed" (Type D) personality trait has been reported to be over-represented in patients with heart failure (HF) compared to the background population and may provide prognostic information for mortality. We examined the association between Type D personality and outcomes in the DANISH trial (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators in Patients with Non-ischemic Systolic Heart Failure on Mortality).METHODS: The DANISH trial included a total of 1116 patients with non-ischemic HF on guideline-recommended therapy. Type D personality was assessed with the Type D Scale (DS14) at baseline and investigated through follow-up accordingly. Multivariable Cox proportional hazard models were used to compare hazard ratios (HR) of cardiovascular and all-cause mortality.RESULTS: Type D personality assessment was completed by 873 (78%) patients at baseline and Type D personality was found in 120 (14%) patients. The median follow-up was 67 months (interquartile range [IQR] 48-83). Among patients with versus without Type D personality, 22% versus 19% died from all-cause yielding similar incidence rates of 4.62 (95% CI 3.14-6.87) versus 3.95 (95% CI 3.37-4.66) per 100 person-years. The adjusted risk of all-cause mortality was not significantly different in patients with versus without Type D personality with an adjusted HR of 1.31 (95% CI 0.84-2.03, p = 0.23) with similar results for cardiovascular death (HR 1.46 (95% CI 0.88-2.44, p = 0.15).CONCLUSION: Type D personality was not significantly associated with increased risk of all-cause mortality or cardiovascular death in patients with non-ischemic HF.
AB - PURPOSE: The "distressed" (Type D) personality trait has been reported to be over-represented in patients with heart failure (HF) compared to the background population and may provide prognostic information for mortality. We examined the association between Type D personality and outcomes in the DANISH trial (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators in Patients with Non-ischemic Systolic Heart Failure on Mortality).METHODS: The DANISH trial included a total of 1116 patients with non-ischemic HF on guideline-recommended therapy. Type D personality was assessed with the Type D Scale (DS14) at baseline and investigated through follow-up accordingly. Multivariable Cox proportional hazard models were used to compare hazard ratios (HR) of cardiovascular and all-cause mortality.RESULTS: Type D personality assessment was completed by 873 (78%) patients at baseline and Type D personality was found in 120 (14%) patients. The median follow-up was 67 months (interquartile range [IQR] 48-83). Among patients with versus without Type D personality, 22% versus 19% died from all-cause yielding similar incidence rates of 4.62 (95% CI 3.14-6.87) versus 3.95 (95% CI 3.37-4.66) per 100 person-years. The adjusted risk of all-cause mortality was not significantly different in patients with versus without Type D personality with an adjusted HR of 1.31 (95% CI 0.84-2.03, p = 0.23) with similar results for cardiovascular death (HR 1.46 (95% CI 0.88-2.44, p = 0.15).CONCLUSION: Type D personality was not significantly associated with increased risk of all-cause mortality or cardiovascular death in patients with non-ischemic HF.
KW - Aged
KW - Defibrillators, Implantable/standards
KW - Female
KW - Heart Failure/mortality
KW - Humans
KW - Male
KW - Middle Aged
KW - Prognosis
KW - Quality of Life/psychology
KW - Risk Factors
KW - Type D Personality
U2 - 10.1007/s11136-019-02241-6
DO - 10.1007/s11136-019-02241-6
M3 - Journal article
C2 - 31292822
VL - 28
SP - 2901
EP - 2908
JO - Quality of Life Research
JF - Quality of Life Research
SN - 0962-9343
IS - 11
ER -
ID: 237148037