A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics

Research output: Contribution to journalReviewResearchpeer-review

Standard

A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics. / Yew, Yik Weng; Thyssen, Jacob P; Silverberg, Jonathan I.

In: Journal of the American Academy of Dermatology, Vol. 80, No. 2, 02.2019, p. 390-401.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Yew, YW, Thyssen, JP & Silverberg, JI 2019, 'A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics', Journal of the American Academy of Dermatology, vol. 80, no. 2, pp. 390-401. https://doi.org/10.1016/j.jaad.2018.09.035

APA

Yew, Y. W., Thyssen, J. P., & Silverberg, J. I. (2019). A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics. Journal of the American Academy of Dermatology, 80(2), 390-401. https://doi.org/10.1016/j.jaad.2018.09.035

Vancouver

Yew YW, Thyssen JP, Silverberg JI. A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics. Journal of the American Academy of Dermatology. 2019 Feb;80(2):390-401. https://doi.org/10.1016/j.jaad.2018.09.035

Author

Yew, Yik Weng ; Thyssen, Jacob P ; Silverberg, Jonathan I. / A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics. In: Journal of the American Academy of Dermatology. 2019 ; Vol. 80, No. 2. pp. 390-401.

Bibtex

@article{f085d12179444d5dbd387275b08b4323,
title = "A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics",
abstract = "BACKGROUND: Previous studies found conflicting results about the commonality of different atopic dermatitis (AD) signs and symptoms.OBJECTIVE: To determine the prevalences of AD characteristics and differences by region and age.METHODS: A systematic review was performed of all published studies in MEDLINE, EMBASE, SCOPUS, LILACS, Cochrane, China National Knowledge Infrastructure, Taiwan Electronic Periodical Services, and CiNii that analyzed the proportion of AD characteristics. Two reviewers performed a review study titles and/or abstracts and data abstraction.RESULTS: In all, 101 studies reported proportion of AD features with sufficient data for meta-analysis. The most prevalent AD features were pruritus, lichenification, and xerosis. There were differences in AD characteristics by study region. Flexural involvement was less commonly reported in India, the Americas, and Iran. Studies from East Asian reported more erythroderma and truncal, extensor, scalp, and auricular involvement. Studies from Southeast Asia reported more exudative eczema, truncal involvement, lichenification, and prurigo nodularis. Studies from Iran reported more head, face, and neck involvement; pityriasis alba; and xerosis. Studies from Africa reported more papular lichenoid lesions, palmar hyperlinearity, ichthyosis, and orbital darkening.LIMITATIONS: Heterogeneity between studies and limited reporting of certain AD clinical characteristics.CONCLUSIONS: AD characteristics are heterogeneous and vary by region and age.",
keywords = "Adolescent, Adult, Age of Onset, Biopsy, Needle, Child, Dermatitis, Atopic/diagnosis, Disease Progression, Female, Humans, Immunohistochemistry, Internationality, Male, Prevalence, Prognosis, Risk Assessment, Severity of Illness Index, Young Adult",
author = "Yew, {Yik Weng} and Thyssen, {Jacob P} and Silverberg, {Jonathan I}",
note = "Copyright {\circledC} 2018 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.",
year = "2019",
month = "2",
doi = "10.1016/j.jaad.2018.09.035",
language = "English",
volume = "80",
pages = "390--401",
journal = "American Academy of Dermatology. Journal",
issn = "0190-9622",
publisher = "Mosby Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics

AU - Yew, Yik Weng

AU - Thyssen, Jacob P

AU - Silverberg, Jonathan I

N1 - Copyright © 2018 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

PY - 2019/2

Y1 - 2019/2

N2 - BACKGROUND: Previous studies found conflicting results about the commonality of different atopic dermatitis (AD) signs and symptoms.OBJECTIVE: To determine the prevalences of AD characteristics and differences by region and age.METHODS: A systematic review was performed of all published studies in MEDLINE, EMBASE, SCOPUS, LILACS, Cochrane, China National Knowledge Infrastructure, Taiwan Electronic Periodical Services, and CiNii that analyzed the proportion of AD characteristics. Two reviewers performed a review study titles and/or abstracts and data abstraction.RESULTS: In all, 101 studies reported proportion of AD features with sufficient data for meta-analysis. The most prevalent AD features were pruritus, lichenification, and xerosis. There were differences in AD characteristics by study region. Flexural involvement was less commonly reported in India, the Americas, and Iran. Studies from East Asian reported more erythroderma and truncal, extensor, scalp, and auricular involvement. Studies from Southeast Asia reported more exudative eczema, truncal involvement, lichenification, and prurigo nodularis. Studies from Iran reported more head, face, and neck involvement; pityriasis alba; and xerosis. Studies from Africa reported more papular lichenoid lesions, palmar hyperlinearity, ichthyosis, and orbital darkening.LIMITATIONS: Heterogeneity between studies and limited reporting of certain AD clinical characteristics.CONCLUSIONS: AD characteristics are heterogeneous and vary by region and age.

AB - BACKGROUND: Previous studies found conflicting results about the commonality of different atopic dermatitis (AD) signs and symptoms.OBJECTIVE: To determine the prevalences of AD characteristics and differences by region and age.METHODS: A systematic review was performed of all published studies in MEDLINE, EMBASE, SCOPUS, LILACS, Cochrane, China National Knowledge Infrastructure, Taiwan Electronic Periodical Services, and CiNii that analyzed the proportion of AD characteristics. Two reviewers performed a review study titles and/or abstracts and data abstraction.RESULTS: In all, 101 studies reported proportion of AD features with sufficient data for meta-analysis. The most prevalent AD features were pruritus, lichenification, and xerosis. There were differences in AD characteristics by study region. Flexural involvement was less commonly reported in India, the Americas, and Iran. Studies from East Asian reported more erythroderma and truncal, extensor, scalp, and auricular involvement. Studies from Southeast Asia reported more exudative eczema, truncal involvement, lichenification, and prurigo nodularis. Studies from Iran reported more head, face, and neck involvement; pityriasis alba; and xerosis. Studies from Africa reported more papular lichenoid lesions, palmar hyperlinearity, ichthyosis, and orbital darkening.LIMITATIONS: Heterogeneity between studies and limited reporting of certain AD clinical characteristics.CONCLUSIONS: AD characteristics are heterogeneous and vary by region and age.

KW - Adolescent

KW - Adult

KW - Age of Onset

KW - Biopsy, Needle

KW - Child

KW - Dermatitis, Atopic/diagnosis

KW - Disease Progression

KW - Female

KW - Humans

KW - Immunohistochemistry

KW - Internationality

KW - Male

KW - Prevalence

KW - Prognosis

KW - Risk Assessment

KW - Severity of Illness Index

KW - Young Adult

U2 - 10.1016/j.jaad.2018.09.035

DO - 10.1016/j.jaad.2018.09.035

M3 - Review

C2 - 30287309

VL - 80

SP - 390

EP - 401

JO - American Academy of Dermatology. Journal

JF - American Academy of Dermatology. Journal

SN - 0190-9622

IS - 2

ER -

ID: 235914641