Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather: a questionnaire study

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Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather : a questionnaire study. / Bregnbak, David; Thyssen, Jacob P; Zachariae, Claus; Johansen, Jeanne D.

In: Contact Dermatitis, Vol. 71, No. 6, 12.2014, p. 338–347.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Bregnbak, D, Thyssen, JP, Zachariae, C & Johansen, JD 2014, 'Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather: a questionnaire study', Contact Dermatitis, vol. 71, no. 6, pp. 338–347. https://doi.org/10.1111/cod.12291

APA

Bregnbak, D., Thyssen, J. P., Zachariae, C., & Johansen, J. D. (2014). Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather: a questionnaire study. Contact Dermatitis, 71(6), 338–347. https://doi.org/10.1111/cod.12291

Vancouver

Bregnbak D, Thyssen JP, Zachariae C, Johansen JD. Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather: a questionnaire study. Contact Dermatitis. 2014 Dec;71(6):338–347. https://doi.org/10.1111/cod.12291

Author

Bregnbak, David ; Thyssen, Jacob P ; Zachariae, Claus ; Johansen, Jeanne D. / Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather : a questionnaire study. In: Contact Dermatitis. 2014 ; Vol. 71, No. 6. pp. 338–347.

Bibtex

@article{8e1745165f8144be958c243a0ea0b178,
title = "Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather: a questionnaire study",
abstract = "BACKGROUND: Chromium-tanned leather articles currently constitute the most important cause of contact allergy to chromium in Denmark. A regulation on the content of hexavalent chromium in leather was adopted in November 2013 by the EU member states.OBJECTIVES: To characterize patients with chromium allergy and their disease, to serve as a baseline for future studies on the potential effect of the new regulation on chromium in leather.METHODS: A questionnaire case-control study was performed on 155 dermatitis patients with positive patch test reactions to potassium dichromate and a matched control group of 621 dermatitis patients. Comparisons were made by use of a χ(2) -test and the Mann-Whitney U-test. Logistic regression analyses were used to test for associations.RESULTS: Sixty-six per cent of chromium-allergic patients had a positive history of contact dermatitis caused by leather exposure. They had a significantly lower quality of life (p < 0.001), a higher prevalence of dermatitis during the last year (p = 0.008), a higher use of medication during the past 12 months (p = 0.001) and a higher prevalence of sick leave (p = 0.007) than patients in the control group.CONCLUSIONS: Chromium-allergic patients have more severe and more chronic contact dermatitis. Their primary chromium exposure comes from leather articles.",
author = "David Bregnbak and Thyssen, {Jacob P} and Claus Zachariae and Johansen, {Jeanne D}",
note = "{\circledC} 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2014",
month = "12",
doi = "10.1111/cod.12291",
language = "English",
volume = "71",
pages = "338–347",
journal = "Contact Dermatitis",
issn = "0105-1873",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Characteristics of chromium-allergic dermatitis patients prior to regulatory intervention for chromium in leather

T2 - a questionnaire study

AU - Bregnbak, David

AU - Thyssen, Jacob P

AU - Zachariae, Claus

AU - Johansen, Jeanne D

N1 - © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PY - 2014/12

Y1 - 2014/12

N2 - BACKGROUND: Chromium-tanned leather articles currently constitute the most important cause of contact allergy to chromium in Denmark. A regulation on the content of hexavalent chromium in leather was adopted in November 2013 by the EU member states.OBJECTIVES: To characterize patients with chromium allergy and their disease, to serve as a baseline for future studies on the potential effect of the new regulation on chromium in leather.METHODS: A questionnaire case-control study was performed on 155 dermatitis patients with positive patch test reactions to potassium dichromate and a matched control group of 621 dermatitis patients. Comparisons were made by use of a χ(2) -test and the Mann-Whitney U-test. Logistic regression analyses were used to test for associations.RESULTS: Sixty-six per cent of chromium-allergic patients had a positive history of contact dermatitis caused by leather exposure. They had a significantly lower quality of life (p < 0.001), a higher prevalence of dermatitis during the last year (p = 0.008), a higher use of medication during the past 12 months (p = 0.001) and a higher prevalence of sick leave (p = 0.007) than patients in the control group.CONCLUSIONS: Chromium-allergic patients have more severe and more chronic contact dermatitis. Their primary chromium exposure comes from leather articles.

AB - BACKGROUND: Chromium-tanned leather articles currently constitute the most important cause of contact allergy to chromium in Denmark. A regulation on the content of hexavalent chromium in leather was adopted in November 2013 by the EU member states.OBJECTIVES: To characterize patients with chromium allergy and their disease, to serve as a baseline for future studies on the potential effect of the new regulation on chromium in leather.METHODS: A questionnaire case-control study was performed on 155 dermatitis patients with positive patch test reactions to potassium dichromate and a matched control group of 621 dermatitis patients. Comparisons were made by use of a χ(2) -test and the Mann-Whitney U-test. Logistic regression analyses were used to test for associations.RESULTS: Sixty-six per cent of chromium-allergic patients had a positive history of contact dermatitis caused by leather exposure. They had a significantly lower quality of life (p < 0.001), a higher prevalence of dermatitis during the last year (p = 0.008), a higher use of medication during the past 12 months (p = 0.001) and a higher prevalence of sick leave (p = 0.007) than patients in the control group.CONCLUSIONS: Chromium-allergic patients have more severe and more chronic contact dermatitis. Their primary chromium exposure comes from leather articles.

U2 - 10.1111/cod.12291

DO - 10.1111/cod.12291

M3 - Journal article

C2 - 25142070

VL - 71

SP - 338

EP - 347

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 6

ER -

ID: 137618194