Incidence and prevalence of psoriatic arthritis in Denmark: A nationwide register linkage study

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Incidence and prevalence of psoriatic arthritis in Denmark : A nationwide register linkage study. / Egeberg, Alexander; Kristensen, Lars Erik; Thyssen, Jacob P.; Gislason, Gunnar Hilmar; Gottlieb, Alice B.; Coates, Laura C.; Jullien, Denis; Gisondi, Paolo; Gladman, Dafna D.; Skov, Lone; Mallbris, Lotus.

In: Annals of the Rheumatic Diseases, Vol. 76, No. 9, 2017, p. 1591-1597.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Egeberg, A, Kristensen, LE, Thyssen, JP, Gislason, GH, Gottlieb, AB, Coates, LC, Jullien, D, Gisondi, P, Gladman, DD, Skov, L & Mallbris, L 2017, 'Incidence and prevalence of psoriatic arthritis in Denmark: A nationwide register linkage study', Annals of the Rheumatic Diseases, vol. 76, no. 9, pp. 1591-1597. https://doi.org/10.1136/annrheumdis-2016-210963

APA

Egeberg, A., Kristensen, L. E., Thyssen, J. P., Gislason, G. H., Gottlieb, A. B., Coates, L. C., ... Mallbris, L. (2017). Incidence and prevalence of psoriatic arthritis in Denmark: A nationwide register linkage study. Annals of the Rheumatic Diseases, 76(9), 1591-1597. https://doi.org/10.1136/annrheumdis-2016-210963

Vancouver

Egeberg A, Kristensen LE, Thyssen JP, Gislason GH, Gottlieb AB, Coates LC et al. Incidence and prevalence of psoriatic arthritis in Denmark: A nationwide register linkage study. Annals of the Rheumatic Diseases. 2017;76(9):1591-1597. https://doi.org/10.1136/annrheumdis-2016-210963

Author

Egeberg, Alexander ; Kristensen, Lars Erik ; Thyssen, Jacob P. ; Gislason, Gunnar Hilmar ; Gottlieb, Alice B. ; Coates, Laura C. ; Jullien, Denis ; Gisondi, Paolo ; Gladman, Dafna D. ; Skov, Lone ; Mallbris, Lotus. / Incidence and prevalence of psoriatic arthritis in Denmark : A nationwide register linkage study. In: Annals of the Rheumatic Diseases. 2017 ; Vol. 76, No. 9. pp. 1591-1597.

Bibtex

@article{a657946298da4210915549d191df8928,
title = "Incidence and prevalence of psoriatic arthritis in Denmark: A nationwide register linkage study",
abstract = "Objectives: To examine the incidence and temporal trends of psoriatic arthritis (PsA) in the general population in Denmark. Methods: Using nationwide registry data, we estimated the number of patients with incident PsA within each 1-year period between 1997 and 2011 and calculated the rate of PsA cases within gender and age subgroups. Incidence rates were presented per 100 000 person-years. Results: There was a female predominance ranging from 50.3{\%} (1998) to 59.2{\%} (2010), and the mean age at time of diagnosis was 47-50 years. We identified a total of 12 719 patients with PsA (prevalence=0.22{\%}), including 9034 patients where the PsA diagnosis was made by a rheumatologist (prevalence=0.16{\%}). Incidence rates of PsA (per 100 000 person-years) increased from 7.3 in 1997 to a peak incidence of 27.3 in 2010. Incidence rates were highest for women and patients aged 50-59 years, respectively. The use of systemic non-biologic agents, that is, methotrexate, leflunomide, ciclosporin or sulfasalazine increased over the 15-year study course and were used in 66.3{\%} of all patients. Biologic agents (etanercept, infliximab, adalimumab, certolizumab pegol, golimumab or ustekinumab) were used in 17.7{\%} of patients with PsA. Conclusions: We found a clear trend of rising PsA incidence on a national level. While the cause remains unclear, our findings might be explained by increased attention by patients and physicians.",
keywords = "Epidemiology, Incidence, Prevalence, Psoriatic arthritis, Time trends",
author = "Alexander Egeberg and Kristensen, {Lars Erik} and Thyssen, {Jacob P.} and Gislason, {Gunnar Hilmar} and Gottlieb, {Alice B.} and Coates, {Laura C.} and Denis Jullien and Paolo Gisondi and Gladman, {Dafna D.} and Lone Skov and Lotus Mallbris",
year = "2017",
doi = "10.1136/annrheumdis-2016-210963",
language = "English",
volume = "76",
pages = "1591--1597",
journal = "Annals of the Rheumatic Diseases",
issn = "0003-4967",
publisher = "B M J Group",
number = "9",

}

RIS

TY - JOUR

T1 - Incidence and prevalence of psoriatic arthritis in Denmark

T2 - A nationwide register linkage study

AU - Egeberg, Alexander

AU - Kristensen, Lars Erik

AU - Thyssen, Jacob P.

AU - Gislason, Gunnar Hilmar

AU - Gottlieb, Alice B.

AU - Coates, Laura C.

AU - Jullien, Denis

AU - Gisondi, Paolo

AU - Gladman, Dafna D.

AU - Skov, Lone

AU - Mallbris, Lotus

PY - 2017

Y1 - 2017

N2 - Objectives: To examine the incidence and temporal trends of psoriatic arthritis (PsA) in the general population in Denmark. Methods: Using nationwide registry data, we estimated the number of patients with incident PsA within each 1-year period between 1997 and 2011 and calculated the rate of PsA cases within gender and age subgroups. Incidence rates were presented per 100 000 person-years. Results: There was a female predominance ranging from 50.3% (1998) to 59.2% (2010), and the mean age at time of diagnosis was 47-50 years. We identified a total of 12 719 patients with PsA (prevalence=0.22%), including 9034 patients where the PsA diagnosis was made by a rheumatologist (prevalence=0.16%). Incidence rates of PsA (per 100 000 person-years) increased from 7.3 in 1997 to a peak incidence of 27.3 in 2010. Incidence rates were highest for women and patients aged 50-59 years, respectively. The use of systemic non-biologic agents, that is, methotrexate, leflunomide, ciclosporin or sulfasalazine increased over the 15-year study course and were used in 66.3% of all patients. Biologic agents (etanercept, infliximab, adalimumab, certolizumab pegol, golimumab or ustekinumab) were used in 17.7% of patients with PsA. Conclusions: We found a clear trend of rising PsA incidence on a national level. While the cause remains unclear, our findings might be explained by increased attention by patients and physicians.

AB - Objectives: To examine the incidence and temporal trends of psoriatic arthritis (PsA) in the general population in Denmark. Methods: Using nationwide registry data, we estimated the number of patients with incident PsA within each 1-year period between 1997 and 2011 and calculated the rate of PsA cases within gender and age subgroups. Incidence rates were presented per 100 000 person-years. Results: There was a female predominance ranging from 50.3% (1998) to 59.2% (2010), and the mean age at time of diagnosis was 47-50 years. We identified a total of 12 719 patients with PsA (prevalence=0.22%), including 9034 patients where the PsA diagnosis was made by a rheumatologist (prevalence=0.16%). Incidence rates of PsA (per 100 000 person-years) increased from 7.3 in 1997 to a peak incidence of 27.3 in 2010. Incidence rates were highest for women and patients aged 50-59 years, respectively. The use of systemic non-biologic agents, that is, methotrexate, leflunomide, ciclosporin or sulfasalazine increased over the 15-year study course and were used in 66.3% of all patients. Biologic agents (etanercept, infliximab, adalimumab, certolizumab pegol, golimumab or ustekinumab) were used in 17.7% of patients with PsA. Conclusions: We found a clear trend of rising PsA incidence on a national level. While the cause remains unclear, our findings might be explained by increased attention by patients and physicians.

KW - Epidemiology

KW - Incidence

KW - Prevalence

KW - Psoriatic arthritis

KW - Time trends

U2 - 10.1136/annrheumdis-2016-210963

DO - 10.1136/annrheumdis-2016-210963

M3 - Journal article

C2 - 28483767

AN - SCOPUS:85027461536

VL - 76

SP - 1591

EP - 1597

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

SN - 0003-4967

IS - 9

ER -

ID: 189668601