Leif Breum

Leif Breum

Clinical Associate Professor

Member of:

  • Internal Medicine: Endocrinology


  1. 2023
  2. Published

    Quality of life, patient satisfaction, and cardiovascular outcomes of the randomised 2 x 3 factorial Copenhagen insulin and Metformin therapy (CIMT) trial – A detailed statistical analysis plan

    Olsen, M. H., Almdal, Thomas Peter, Madsbad, Sten, Ovesen, C., Gluud, C., Sneppen, S. B., Breum, Leif, Hedetoft, C., Krarup, T., Lundby-Christensen, L., Mathiesen, Elisabeth, Røder, M. E., drb459, drb459, Wiinberg, N. & Jakobsen, J. C., 2023, In: Contemporary Clinical Trials Communications. 33, 101095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2022
  4. Published

    Effects of 18-months metformin versus placebo in combination with three insulin regimens on RNA and DNA oxidation in individuals with type 2 diabetes: A post-hoc analysis of a randomized clinical trial

    Larsen, E. L., Kjær, L. K., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gluud, C., Hedetoft, C., Krarup, T., Lund, S. S., Mathiesen, Elisabeth, Perrild, Hans, Sneppen, S. B., Tarnow, L., Thorsteinsson, B., drb459, drb459, Poulsen, Henrik Enghusen, Madsbad, Sten & Almdal, Thomas Peter, 2022, In: Free Radical Biology and Medicine. 178, p. 18-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2021
  6. Published

    Effect of metformin and insulin vs. placebo and insulin on whole body composition in overweight patients with type 2 diabetes: a randomized placebo-controlled trial

    Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Perrild, Hans, Madsbad, Sten, Mathiesen, Elisabeth, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2021, In: Osteoporosis International. 32, p. 1837–1848

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2020
  8. Published

    Prediction of carotid intima-media thickness and its relation to cardiovascular events in persons with type 2 diabetes

    Winckler, K., Thorsteinsson, B., Wiinberg, N., Jensen, Andreas Kryger, Lundby-Christensen, L., Heitmann, Berit, Lund, S. S., Krarup, T., Jensen, T., Vestergaard, H., Breum, Leif, Sneppen, S., Boesgaard, T., Madsbad, Sten, Gluud, C., Vaag, A., Almdal, Thomas Peter, Tarnow, L. & The CIMT trial group, T. C. T. G., Oct 2020, In: Journal of Diabetes and its Complications. 34, 10, 107681.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effect of Metformin vs. Placebo in Combination with Insulin Analogues on Bone Markers P1NP and CTX in Patients with Type 2 Diabetes Mellitus

    Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Jørgensen, Niklas Rye, Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., Vestergaard, H., Lund, S. S. & Eiken, P., 2020, In: Calcified Tissue International. 107, 2, p. 160-169 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2018
  11. Published

    The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial

    Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2016
  13. Published

    Search for supersymmetry at root s=13 TeV in final states with jets and two same-sign leptons or three leptons with the ATLAS detector

    Aad, G., Abbott, B., Abdallah, J., Abdinov, O., Abeloos, B., Aben, R., Abolins, M., AbouZeid, O. S., Abramowicz, H., Abreu, H., Breum, L., Abreu, R., Adye, T., Dam, M., Hansen, J. D., Hansen, J. B., Xella, S., Hansen, P. H., Petersen, T. C., Thomsen, L. A. & 7 others, Pingel, A. M., Løvschall-Jensen, A. E., Alonso Diaz, A., Monk, J. W., Pedersen, L. E., Wiglesworth, Graig & Galster, G. A. G. K., 7 May 2016, In: European Physical Journal C. 76, 5, 259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial

    Lundby-Christensen, L., Vaag, A., Tarnow, L., Almdal, T. P., Lund, S. S., Wetterslev, J., Gluud, C., Boesgaard, T. W., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L. & 6 others, Duun, E., Sneppen, S. B., Pedersen, Oluf Borbye, Hemmingsen, B., Carstensen, Bendix & Madsbad, Sten, 2016, In: B M J Open. 6, 2, e008377.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus: the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial

    Lundby-Christensen, L., Tarnow, L., Boesgaard, T. W., Lund, S. S., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L., Duun, E., Sneppen, S. B., Pedersen, O., Hemmingsen, B. & 6 others, Carstensen, Bendix, Madsbad, Sten, Gluud, C., Wetterslev, J., Vaag, Allan & Almdal, Thomas Peter, 2016, In: B M J Open. 6, 2, e008376.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2013
  17. Published

    Under-reporting of adverse effects of tesofensine

    Astrup, A., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2013, In: Lancet. 382, 9887, p. 127 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

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ID: 925943