Thomas Werge
Clinical Professor
Department of Clinical Medicine
Region Hovedstadens Psykiatri, Boserupvej 2, 4000 Roskilde
My research has focused on explaining the biological reasons that contributes to the development of severe mental disorders such as schizophrenia and autism - disorders, that all have great personal and social costs. In the future this knowledge provides us with the tools to diagnose patients on a patient specific level. Further it provides the basis for a personalized drug development. These can have a more directly effect on the diagnosed disease and less side effects compared to current drugs used in treatment of mental disorders. During my research I have taken initiative to create the Danish Psychiatric Biobank, which aims to identify the genetic constellations of mental disorders. Together with other international research groups I have identified changes in the genome that for some carriers can be associated with the development of severe mental disorders. On a daily basis I am PI and Co-PI on several projects that all have the purpose to obtain a thorough explanation of the biological causes of mental disorders. Such kind of work requires a broad interdisciplinary collaboration where the disorders are examined on multiple levels; from genes and cells to population cohorts, and from fetal life to the patient.
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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351
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
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234
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
Published