Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655. / Søndergaard, Helle Bach; Sellebjerg, Finn; Hillert, Jan; Olsson, Tomas; Kockum, Ingrid; Lindén, Magdalena; Mero, Inger-Lise; Myhr, Kjell-Morten; Celius, Elisabeth G; Harbo, Hanne F; Christensen, Jeppe Romme; Börnsen, Lars; Sørensen, Per Soelberg; Oturai, Annette Bang.
I: European Journal of Human Genetics, Bind 19, Nr. 10, 2011, s. 1100-3.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655
AU - Søndergaard, Helle Bach
AU - Sellebjerg, Finn
AU - Hillert, Jan
AU - Olsson, Tomas
AU - Kockum, Ingrid
AU - Lindén, Magdalena
AU - Mero, Inger-Lise
AU - Myhr, Kjell-Morten
AU - Celius, Elisabeth G
AU - Harbo, Hanne F
AU - Christensen, Jeppe Romme
AU - Börnsen, Lars
AU - Sørensen, Per Soelberg
AU - Oturai, Annette Bang
PY - 2011
Y1 - 2011
N2 - Multiple sclerosis (MS) is a complex autoimmune disease affecting genetically susceptible individuals. A genome-wide association study performed by the International MS Genetics Consortium identified several putative susceptibility genes; among these, the KLRB1 gene is represented by the single-nucleotide polymorphism rs4763655. We could confirm a marginally significant association between rs4763655 and MS (P=0.046, odds ratio=1.06 (1.00-1.13)) in a large Scandinavian case-control study of 5367 MS patients and 4485 controls. The expression of KLRB1 in blood from MS patients was higher compared with healthy controls (P
AB - Multiple sclerosis (MS) is a complex autoimmune disease affecting genetically susceptible individuals. A genome-wide association study performed by the International MS Genetics Consortium identified several putative susceptibility genes; among these, the KLRB1 gene is represented by the single-nucleotide polymorphism rs4763655. We could confirm a marginally significant association between rs4763655 and MS (P=0.046, odds ratio=1.06 (1.00-1.13)) in a large Scandinavian case-control study of 5367 MS patients and 4485 controls. The expression of KLRB1 in blood from MS patients was higher compared with healthy controls (P
U2 - http://dx.doi.org/10.1038/ejhg.2011.88
DO - http://dx.doi.org/10.1038/ejhg.2011.88
M3 - Journal article
VL - 19
SP - 1100
EP - 1103
JO - European Journal of Human Genetics
JF - European Journal of Human Genetics
SN - 1018-4813
IS - 10
ER -
ID: 40194303