Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1

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Standard

Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1. / Pires, Carlota; Schmid, Benjamin; Petræus, Carina; Poon, Anna Fong-Yee; Nimsanor, Natakarn; Nielsen, Troels Tolstrup; Waldemar, Gunhild; Hjermind, Lena Elisabeth; Nielsen, Jørgen Erik; Hyttel, Poul; Freude, Kristine.

I: Stem Cell Research, Bind 17, Nr. 2, 09.2016, s. 285-288.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Pires, C, Schmid, B, Petræus, C, Poon, AF-Y, Nimsanor, N, Nielsen, TT, Waldemar, G, Hjermind, LE, Nielsen, JE, Hyttel, P & Freude, K 2016, 'Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1', Stem Cell Research, bind 17, nr. 2, s. 285-288. https://doi.org/10.1016/j.scr.2016.08.002

APA

Pires, C., Schmid, B., Petræus, C., Poon, A. F-Y., Nimsanor, N., Nielsen, T. T., Waldemar, G., Hjermind, L. E., Nielsen, J. E., Hyttel, P., & Freude, K. (2016). Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1. Stem Cell Research, 17(2), 285-288. https://doi.org/10.1016/j.scr.2016.08.002

Vancouver

Pires C, Schmid B, Petræus C, Poon AF-Y, Nimsanor N, Nielsen TT o.a. Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1. Stem Cell Research. 2016 sep.;17(2):285-288. https://doi.org/10.1016/j.scr.2016.08.002

Author

Pires, Carlota ; Schmid, Benjamin ; Petræus, Carina ; Poon, Anna Fong-Yee ; Nimsanor, Natakarn ; Nielsen, Troels Tolstrup ; Waldemar, Gunhild ; Hjermind, Lena Elisabeth ; Nielsen, Jørgen Erik ; Hyttel, Poul ; Freude, Kristine. / Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1. I: Stem Cell Research. 2016 ; Bind 17, Nr. 2. s. 285-288.

Bibtex

@article{8ff051368aff428fb9f2c731750ea26b,
title = "Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1",
abstract = "Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease causing neural cell degeneration and brain atrophy and is considered to be the most common form of dementia. We previously generated an induced pluripotent stem cell (iPSC) line from an AD patient carrying an A79V mutation in PSEN1 as an in vitro disease model. Here we generated a gene-corrected version from this hiPSC line by substituting the point mutation with the wild-type sequence. The reported A79V-GC-iPSCs line is a very useful resource in combination with the A79V-iPSC line in order to study pathological cellular phenotypes related to this particular mutation.",
author = "Carlota Pires and Benjamin Schmid and Carina Petr{\ae}us and Poon, {Anna Fong-Yee} and Natakarn Nimsanor and Nielsen, {Troels Tolstrup} and Gunhild Waldemar and Hjermind, {Lena Elisabeth} and Nielsen, {J{\o}rgen Erik} and Poul Hyttel and Kristine Freude",
note = "Copyright {\textcopyright} 2016 Helmholtz Zentrum M{\"u}nchen. Published by Elsevier B.V. All rights reserved.",
year = "2016",
month = sep,
doi = "10.1016/j.scr.2016.08.002",
language = "English",
volume = "17",
pages = "285--288",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1

AU - Pires, Carlota

AU - Schmid, Benjamin

AU - Petræus, Carina

AU - Poon, Anna Fong-Yee

AU - Nimsanor, Natakarn

AU - Nielsen, Troels Tolstrup

AU - Waldemar, Gunhild

AU - Hjermind, Lena Elisabeth

AU - Nielsen, Jørgen Erik

AU - Hyttel, Poul

AU - Freude, Kristine

N1 - Copyright © 2016 Helmholtz Zentrum München. Published by Elsevier B.V. All rights reserved.

PY - 2016/9

Y1 - 2016/9

N2 - Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease causing neural cell degeneration and brain atrophy and is considered to be the most common form of dementia. We previously generated an induced pluripotent stem cell (iPSC) line from an AD patient carrying an A79V mutation in PSEN1 as an in vitro disease model. Here we generated a gene-corrected version from this hiPSC line by substituting the point mutation with the wild-type sequence. The reported A79V-GC-iPSCs line is a very useful resource in combination with the A79V-iPSC line in order to study pathological cellular phenotypes related to this particular mutation.

AB - Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease causing neural cell degeneration and brain atrophy and is considered to be the most common form of dementia. We previously generated an induced pluripotent stem cell (iPSC) line from an AD patient carrying an A79V mutation in PSEN1 as an in vitro disease model. Here we generated a gene-corrected version from this hiPSC line by substituting the point mutation with the wild-type sequence. The reported A79V-GC-iPSCs line is a very useful resource in combination with the A79V-iPSC line in order to study pathological cellular phenotypes related to this particular mutation.

U2 - 10.1016/j.scr.2016.08.002

DO - 10.1016/j.scr.2016.08.002

M3 - Journal article

C2 - 27879212

VL - 17

SP - 285

EP - 288

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

IS - 2

ER -

ID: 173288754