Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11

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Standard

Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11. / Hansen, Susanne Kofoed; Borland, Helena; Hasholt, Lis Frydenreich; Tümer, Zeynep; Nielsen, Jørgen Erik; Rasmussen, Mikkel A.; Nielsen, Troels Tolstrup; Stummann, Tina C.; Fog, Karina; Hyttel, Poul.

I: Stem Cell Research, Bind 16, Nr. 3, 05.2016, s. 589-592.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hansen, SK, Borland, H, Hasholt, LF, Tümer, Z, Nielsen, JE, Rasmussen, MA, Nielsen, TT, Stummann, TC, Fog, K & Hyttel, P 2016, 'Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11', Stem Cell Research, bind 16, nr. 3, s. 589-592. https://doi.org/10.1016/j.scr.2016.02.042

APA

Hansen, S. K., Borland, H., Hasholt, L. F., Tümer, Z., Nielsen, J. E., Rasmussen, M. A., Nielsen, T. T., Stummann, T. C., Fog, K., & Hyttel, P. (2016). Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11. Stem Cell Research, 16(3), 589-592. https://doi.org/10.1016/j.scr.2016.02.042

Vancouver

Hansen SK, Borland H, Hasholt LF, Tümer Z, Nielsen JE, Rasmussen MA o.a. Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11. Stem Cell Research. 2016 maj;16(3):589-592. https://doi.org/10.1016/j.scr.2016.02.042

Author

Hansen, Susanne Kofoed ; Borland, Helena ; Hasholt, Lis Frydenreich ; Tümer, Zeynep ; Nielsen, Jørgen Erik ; Rasmussen, Mikkel A. ; Nielsen, Troels Tolstrup ; Stummann, Tina C. ; Fog, Karina ; Hyttel, Poul. / Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11. I: Stem Cell Research. 2016 ; Bind 16, Nr. 3. s. 589-592.

Bibtex

@article{d2c41482f919451799c989c32f77b47b,
title = "Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11",
abstract = "Spinocerebellar ataxia type 3 (SCA3) is a dominantly inherited neurodegenerative disease caused by an expansion of the CAG-repeat in ATXN3. In this study, induced pluripotent stem cells (iPSCs) were generated from SCA3 patient dermal fibroblasts by electroporation with episomal plasmids encoding L-MYC, LIN28, SOX2, KLF4, OCT4 and short hairpin RNA targeting P53. The resulting iPSCs had normal karyotype, were free of integrated episomal plasmids, expressed pluripotency markers, could differentiate into the three germ layers in vitro and retained the disease-causing ATXN3 mutation. Potentially, this iPSC line could be a useful tool for the investigation of SCA3 disease mechanisms.",
author = "Hansen, {Susanne Kofoed} and Helena Borland and Hasholt, {Lis Frydenreich} and Zeynep T{\"u}mer and Nielsen, {J{\o}rgen Erik} and Rasmussen, {Mikkel A.} and Nielsen, {Troels Tolstrup} and Stummann, {Tina C.} and Karina Fog and Poul Hyttel",
year = "2016",
month = may,
doi = "10.1016/j.scr.2016.02.042",
language = "English",
volume = "16",
pages = "589--592",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line SCA3.B11

AU - Hansen, Susanne Kofoed

AU - Borland, Helena

AU - Hasholt, Lis Frydenreich

AU - Tümer, Zeynep

AU - Nielsen, Jørgen Erik

AU - Rasmussen, Mikkel A.

AU - Nielsen, Troels Tolstrup

AU - Stummann, Tina C.

AU - Fog, Karina

AU - Hyttel, Poul

PY - 2016/5

Y1 - 2016/5

N2 - Spinocerebellar ataxia type 3 (SCA3) is a dominantly inherited neurodegenerative disease caused by an expansion of the CAG-repeat in ATXN3. In this study, induced pluripotent stem cells (iPSCs) were generated from SCA3 patient dermal fibroblasts by electroporation with episomal plasmids encoding L-MYC, LIN28, SOX2, KLF4, OCT4 and short hairpin RNA targeting P53. The resulting iPSCs had normal karyotype, were free of integrated episomal plasmids, expressed pluripotency markers, could differentiate into the three germ layers in vitro and retained the disease-causing ATXN3 mutation. Potentially, this iPSC line could be a useful tool for the investigation of SCA3 disease mechanisms.

AB - Spinocerebellar ataxia type 3 (SCA3) is a dominantly inherited neurodegenerative disease caused by an expansion of the CAG-repeat in ATXN3. In this study, induced pluripotent stem cells (iPSCs) were generated from SCA3 patient dermal fibroblasts by electroporation with episomal plasmids encoding L-MYC, LIN28, SOX2, KLF4, OCT4 and short hairpin RNA targeting P53. The resulting iPSCs had normal karyotype, were free of integrated episomal plasmids, expressed pluripotency markers, could differentiate into the three germ layers in vitro and retained the disease-causing ATXN3 mutation. Potentially, this iPSC line could be a useful tool for the investigation of SCA3 disease mechanisms.

U2 - 10.1016/j.scr.2016.02.042

DO - 10.1016/j.scr.2016.02.042

M3 - Journal article

C2 - 27346191

VL - 16

SP - 589

EP - 592

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

IS - 3

ER -

ID: 163128558