High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
The level of soluble vascular endothelial growth factor receptor 1 (sVEGFR1) is increased in sepsis and strongly associated with disease severity and mortality. Endothelial activation and damage contribute to both sepsis and trauma pathology. Therefore, this study measured sVEGFR1 levels in trauma patients upon hospital admission hypothesizing that sVEGFR1 would increase with higher injury severity and predict a poor outcome.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine |
Vol/bind | 20 |
Sider (fra-til) | 27 |
ISSN | 1757-7241 |
DOI | |
Status | Udgivet - 2012 |
ID: 48509318