European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2019 Update
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2019 Update. / Sweet, David G.; Carnielli, Virgilio; Greisen, Gorm; Hallman, Mikko; Ozek, Eren; Te Pas, Arjan; Plavka, Richard; Roehr, Charles C.; Saugstad, Ola D.; Simeoni, Umberto; Speer, Christian P.; Vento, Maximo; Visser, Gerhard H.A.; Halliday, Henry L.
I: Neonatology, Bind 115, Nr. 4, 2019, s. 432-450.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2019 Update
AU - Sweet, David G.
AU - Carnielli, Virgilio
AU - Greisen, Gorm
AU - Hallman, Mikko
AU - Ozek, Eren
AU - Te Pas, Arjan
AU - Plavka, Richard
AU - Roehr, Charles C.
AU - Saugstad, Ola D.
AU - Simeoni, Umberto
AU - Speer, Christian P.
AU - Vento, Maximo
AU - Visser, Gerhard H.A.
AU - Halliday, Henry L.
PY - 2019
Y1 - 2019
N2 - As management of respiratory distress syndrome (RDS) advances, clinicians must continually revise their current practice. We report the fourth update of "European Guidelines for the Management of RDS" by a European panel of experienced neonatologists and an expert perinatal obstetrician based on available literature up to the end of 2018. Optimising outcome for babies with RDS includes prediction of risk of preterm delivery, need for appropriate maternal transfer to a perinatal centre and timely use of antenatal steroids. Delivery room management has become more evidence-based, and protocols for lung protection including initiation of CPAP and titration of oxygen should be implemented immediately after birth. Surfactant replacement therapy is a crucial part of management of RDS, and newer protocols for its use recommend early administration and avoidance of mechanical ventilation. Methods of maintaining babies on non-invasive respiratory support have been further developed and may cause less distress and reduce chronic lung disease. As technology for delivering mechanical ventilation improves, the risk of causing lung injury should decrease, although minimising time spent on mechanical ventilation using caffeine and, if necessary, postnatal steroids are also important considerations. Protocols for optimising general care of infants with RDS are also essential with good temperature control, careful fluid and nutritional management, maintenance of perfusion and judicious use of antibiotics all being important determinants of best outcome.
AB - As management of respiratory distress syndrome (RDS) advances, clinicians must continually revise their current practice. We report the fourth update of "European Guidelines for the Management of RDS" by a European panel of experienced neonatologists and an expert perinatal obstetrician based on available literature up to the end of 2018. Optimising outcome for babies with RDS includes prediction of risk of preterm delivery, need for appropriate maternal transfer to a perinatal centre and timely use of antenatal steroids. Delivery room management has become more evidence-based, and protocols for lung protection including initiation of CPAP and titration of oxygen should be implemented immediately after birth. Surfactant replacement therapy is a crucial part of management of RDS, and newer protocols for its use recommend early administration and avoidance of mechanical ventilation. Methods of maintaining babies on non-invasive respiratory support have been further developed and may cause less distress and reduce chronic lung disease. As technology for delivering mechanical ventilation improves, the risk of causing lung injury should decrease, although minimising time spent on mechanical ventilation using caffeine and, if necessary, postnatal steroids are also important considerations. Protocols for optimising general care of infants with RDS are also essential with good temperature control, careful fluid and nutritional management, maintenance of perfusion and judicious use of antibiotics all being important determinants of best outcome.
KW - Antenatal steroids
KW - Continuous positive airway pressure
KW - Evidence-based practice
KW - Hyaline membrane disease
KW - Mechanical ventilation
KW - Nutrition
KW - Oxygen supplementation
KW - Patent ductus arteriosus
KW - Preterm infant
KW - Respiratory distress syndrome
KW - Surfactant therapy
KW - Thermoregulation
U2 - 10.1159/000499361
DO - 10.1159/000499361
M3 - Review
C2 - 30974433
AN - SCOPUS:85064351036
VL - 115
SP - 432
EP - 450
JO - Neonatology
JF - Neonatology
SN - 1661-7800
IS - 4
ER -
ID: 236322816