Ole Mathiesen

Ole Mathiesen

Clinical Professor

Member of:

  • Anaesthesiology


  1. 2021
  2. Published

    Cardiovascular events in patients undergoing hip fracture surgery treated with remote ischaemic preconditioning: 1-year follow-up of a randomised clinical trial

    Ekeloef, S., Koyuncu, S., Holst-Knudsen, J., Gundel, O., Meyhoff, Christian Sylvest, Homilius, M., Stilling, M., Ekeloef, P., Münster, A. M. B., Mathiesen, Ole & Gögenur, Ismail, 2021, In: Anaesthesia. 76, 8, p. 1042-1050 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Health care use before and after intensive care unit admission—A nationwide register-based study

    Estrup, S., Thygesen, L. C., Poulsen, L. M., Gögenur, Ismail & Mathiesen, Ole, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 3, p. 381-389

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Implementation of a multidisciplinary perioperative protocol in major emergency abdominal surgery

    Burcharth, J., Abdulhady, L., Danker, J., Ekeloef, S., Jørgensen, Thomas, Lauridsen, H., Lunen, T. B., Lyngesen, M., Puggaard, I., Mathiesen, Ole & Gögenur, Ismail, 2021, In: European Journal of Trauma and Emergency Surgery. 47, p. 467–477 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Ketamine for post-operative pain treatment in spinal surgery: A protocol for a systematic review with meta-analysis and trial sequential analysis

    Pind, A. H., Laursen, C. C., Andersen, C., Maagaard, M. & Mathiesen, Ole, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 1, p. 28-134

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Methodologies for systematic reviews with meta-analysis of randomised clinical trials in pain, anaesthesia, and perioperative medicine

    Doleman, B., Mathiesen, Ole, Jakobsen, J. C., Sutton, A. J., Freeman, S., Lund, J. N. & Williams, J. P., 2021, In: British Journal of Anaesthesia. 126, 4, p. 903-911 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Minimal clinically important differences in randomised clinical trials on pain management after total hip and knee arthroplasty: a systematic review

    Laigaard, J., Pedersen, C., Rønsbo, T. N., Mathiesen, Ole & Karlsen, A. P. H., 2021, In: British Journal of Anaesthesia. 126, 5, p. 1029-1037

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Paracetamol, NSAIDs, and glucocorticoids for postoperative pain: a protocol for a systematic review with meta-analysis and Trial Sequential Analysis

    Stormholt, E. R., Steiness, J., Derby, C. B., Larsen, M. E., Maagaard, M. & Mathiesen, Ole, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 10, p. 1505-1513

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Participants with mild, moderate, or severe pain following total hip arthroplasty. A sub-study of the PANSAID trial on paracetamol and ibuprofen for postoperative pain treatment

    Issa, L. M., Thybo, K. H., Hägi-Pedersen, Daniel, Wetterslev, J., Jakobsen, J. C., Overgaard, Søren & Mathiesen, Ole, 2021, In: Scandinavian Journal of Pain. 21, 2, p. 384-392

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Patient-important outcomes other than mortality in recent ICU trials: protocol for a scoping review

    Granholm, A., Kaas-Hansen, Benjamin Skov, Kjaer, M. N., Anthon, C. T., Sivapalan, P., Schjørring, O. L., Andersen, L. W., Mathiesen, Ole, Strøm, T., Jensen, Aksel Karl Georg, Perner, Anders & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 7, p. 1002-1007 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Sleep-wake rhythms determined by actigraphy during in-hospital stay following discharge from an intensive care unit

    Okutan, B., Kjer, C. K. W., Poulsen, L. M., Gögenur, Ismail, Mathiesen, Ole, Estrup, S. & Madsen, M. T., 2021, In: Acta Anaesthesiologica Scandinavica. 65, 6, p. 801-808

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The effect of remote ischaemic preconditioning on endothelial function after hip fracture surgery

    Ekeloef, S., Gundel, O., Falkenberg, A., Mathiesen, Ole & Gögenur, Ismail, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 2, p. 169-175

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2020
  14. Published

    DEX-2-TKA - DEXamethasone twice for pain treatment after Total Knee Arthroplasty: Detailed statistical analysis plan for a randomized, blinded, three-group multicentre clinical trial

    Gasbjerg, K. S., Hägi-Pedersen, Daniel, Lunn, Troels Haxholdt, Overgaard, S., Pedersen, N. A., Bagger, J., Lindholm, P., Brorson, Stig, Schrøder, H. M., Thybo, K. H., Mathiesen, Ole & Jakobsen, J. C., Jul 2020, In: Acta Anaesthesiologica Scandinavica. 64, 6, p. 839-846

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Healthcare providers’ knowledge and handling of impairments after intensive unit treatment: A questionnaire survey

    Jensen, E. K., Poulsen, L. M., Mathiesen, Ole & Estrup, S., Apr 2020, In: Acta Anaesthesiologica Scandinavica. 64, 4, p. 532-537

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Using four different clinical tools as predictors for pain after total hip arthroplasty: a prospective cohort study

    Geisler, A., Zachodnik, J., Laigaard, J., Kruuse, L. S., Sørensen, C. V., Sandberg, M., Persson, E. I. & Mathiesen, Ole, Mar 2020, In: BMC Anesthesiology. 20, 8 p., 57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A retrospective observational study of neuromuscular monitoring practice in 30,430 cases from six Danish hospitals

    Thomsen, J. L. D., Staehr-Rye, A. K., Mathiesen, Ole, Hägi-Pedersen, Daniel & Gätke, M. R., 2020, In: Anaesthesia. 75, 9, p. 1164-1172

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A systematic review of trial registry entries for randomized clinical trials investigating COVID-19 medical prevention and treatment

    Karlsen, A. P. H., Wiberg, S., Laigaard, J., Pedersen, C., Rokamp, K. Z. & Mathiesen, Ole, 2020, In: PLoS ONE. 15, 8, 13 p., e0237903.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Benefits and harm of paracetamol and ibuprofen in combination for post-operative pain: Pre-planned subgroup analyses of the multicenter, randomized PANSAID trial

    Thybo, K. H., Hägi-Pedersen, Daniel, Wetterslev, J., Dahl, J. B., Jakobsen, J. C., Pedersen, N. A., Jakobsen, K., Bülow, H. H., Ibsen, L., Overgaard, S. & Mathiesen, Ole, 2020, In: Acta Anaesthesiologica Scandinavica. 64, 2, p. 245-253 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Cognitive function during opioid tapering in patients with chronic pain: A prospective cohort study

    Laigaard, J., Bache, N., Stottmeier, S., Mathiesen, Ole & Estrup, S., 2020, In: Journal of Pain Research. 13, p. 3385-3394 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    DEX-2-TKA—DEXamethasone twice for pain treatment after Total Knee Arthroplasty: A protocol for a randomized, blinded, three-group multicentre clinical trial

    Gasbjerg, K. S., Hägi-Pedersen, Daniel, Lunn, Troels Haxholdt, Jakobsen, J. C., Overgaard, S., Pedersen, N. A., Bagger, J., Lindholm, P., Brorson, Stig, Schrøder, H. M., Thybo, K. H. & Mathiesen, Ole, 2020, In: Acta Anaesthesiologica Scandinavica. 64, 2, p. 267-275

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Differences in patient characteristics and external validity of randomized clinical trials on pain management following total hip and knee arthroplasty: A systematic review

    Pedersen, C., Troensegaard, H., Laigaard, J., Koyuncu, S., Schrøder, H. M., Overgaard, Søren, Mathiesen, Ole & Karlsen, A. P. H., 2020, In: Regional Anesthesia and Pain Medicine. 45, 9, p. 709-715 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Haloperidol for the treatment of delirium in critically ill patients: A systematic review with meta-analysis and Trial Sequential Analysis

    Barbateskovic, M., Krauss, S. R., Collet, M. O., Andersen-Ranberg, N. C., Mathiesen, Ole, Jakobsen, J. C., Perner, Anders & Wetterslev, J., 2020, In: Acta Anaesthesiologica Scandinavica. 64, 2, p. 254-266 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Mortality and HRQoL in ICU patients with delirium: Protocol for 1-year follow-up of AID-ICU trial

    Mortensen, C. B., Poulsen, L. M., Andersen-Ranberg, N. C., Perner, Anders, Lange, Theis, Estrup, S. S., Ebdrup, Bjørn, Egerod, Ingrid Eugenie, Rasmussen, B. S., Hastbacka, J., Caballero, J., Citerio, G., Morgan, M. P. G., Samuelson, K. & Mathiesen, Ole, 2020, In: Acta Anaesthesiologica Scandinavica. 64, 10, p. 1519-1525 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Recovery after acute illness after hospital discharge: A prospective cohort study

    Ahmed, N., Olesen, K. E. G., Poulsen, L. M., Gögenur, Ismail, Mathiesen, Ole & Estrup, S., 2020, In: Acute Medicine. 19, 3, p. 118-124 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Recurrence and survival rates in node negative patients after sentinel node biopsy for early-stage vulva cancer – A nationwide study

    Froeding, L. P., Høgdall, Claus Kim, Kristensen, E., Zobbe, V., Niemann, I., Ørtoft, G., Thranov, I., Mathiesen, Ole, Mortensen, Jann & Schnack, T. H., 2020, In: Gynecologic Oncology. 156, 1, p. 124-130 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The Agents Intervening against Delirium in the Intensive Care Unit Trial (AID-ICU trial): A detailed statistical analysis plan

    Andersen-Ranberg, N., Poulsen, L. M., Perner, A., Wetterslev, J., Mathiesen, O., Mortensen, C. B., Estrup, S., Ebdrup, B. H., Hästbacka, J., Citerio, G., Caballero, J., Morgan, M. P. G., Oxenbøll-Collet, M., Weber, S. O., Sofie Andreasen, A., Bestle, M. H., Pedersen, H. B. S., Nielsen, L. G., Uslu, B., Jensen, T. B. & 3 others, Thee, C., Dey, N. & Lange, Theis, 2020, In: Acta Anaesthesiologica Scandinavica. 64, 9, p. 1357-1364 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The PANSAID randomized clinical trial: A pre-planned 1-year follow-up regarding harm

    Thybo, K. H., Hägi-Pedersen, Daniel, Wetterslev, J., Overgaard, S. & Mathiesen, Ole, 2020, In: Acta Anaesthesiologica Scandinavica. 64, 7, p. 910-912

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2019
  30. Published

    Intraoperative S-ketamine for the reduction of opioid consumption and pain one year after spine surgery: A randomized clinical trial of opioid-dependent patients

    Nielsen, R. V., Fomsgaard, J. S., Nikolajsen, L., Dahl, J. B. & Mathiesen, Ole, Mar 2019, In: European Journal of Pain. 23, 3, p. 455-460 6 p.

    Research output: Contribution to journalLetterResearchpeer-review

  31. Published

    Agents intervening against delirium in the intensive care unit (AID-ICU) - Protocol for a randomised placebo-controlled trial of haloperidol in patients with delirium in the ICU

    Andersen-Ranberg, N. C., Poulsen, L. M., Perner, A., Wetterslev, J., Estrup, S., Lange, T., Ebdrup, B. H., Hästbacka, J., Morgan, M. P. G., Citerio, G., Zafrani, L., Caballero, J., Oxenbøll-Collet, M., Weber, S-O., Andreasen, A. S., Bestle, M., Pedersen, H. B. S., Hildebrandt, T., Thee, C., Jensen, T. B. & 3 others, Dey, N., Nielsen, L. G. & Mathiesen, Ole, 2019, In: Acta Anaesthesiologica Scandinavica. 63, 10, p. 1426-1433 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Cannabinoids versus placebo or no intervention for pain: protocol for a systematic review with meta-analysis and trial sequential analysis

    Barakji, J. A., Korang, S. K., Feinberg, J., Maagard, M., Gluud, C., Mathiesen, Ole & Jakobsen, J. C., 2019, In: BMJ Open. 9, 10, 11 p., e031574.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours after Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial

    Thybo, K. H., Hägi-Pedersen, Daniel, Dahl, J. B., Wetterslev, J., Nersesjan, M., Jakobsen, J. C., Pedersen, N. A., Overgaard, S., Schrøder, H. M., Schmidt, H., Bjørck, J. G., Skovmand, K., Frederiksen, R., Buus-Nielsen, M., Sørensen, C. V., Kruuse, L. S., Lindholm, P. & Mathiesen, Ole, 2019, In: J A M A: The Journal of the American Medical Association. 321, 6, p. 562-571 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Lateral femoral cutaneous nerve block with different volumes of Ropivacaine: A randomized trial in healthy volunteers

    Vilhelmsen, F., Nersesjan, M., Andersen, Jakob Hessel, Danker, J. K., Broeng, L., Hägi-Pedersen, Daniel, Mathiesen, Ole & Thybo, K. H., 2019, In: BMC Anesthesiology. 19, 8 p., 165.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Pain management after total hip arthroplasty at five different Danish hospitals: A prospective, observational cohort study of 501 patients

    Geisler, A., Dahl, J. B., Thybo, K. H., Pedersen, T. H., Jørgensen, M. L., Hansen, D., Schulze, L. K., Persson, E. I. & Mathiesen, Ole, 2019, In: Acta Anaesthesiologica Scandinavica. 63, 7, p. 923-930 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Physical function and actigraphy in intensive care survivors: A prospective 3-month follow-up cohort study

    Estrup, S., Kjer, C. K. W., Vilhelmsen, F., Poulsen, L. M., Gögenur, Ismail & Mathiesen, Ole, 2019, In: Acta Anaesthesiologica Scandinavica. 63, 5, p. 647-652

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Systemic dexmedetomidine is not as efficient as perineural dexmedetomidine in prolonging an ulnar nerve block

    Andersen, Jakob Hessel, Jaeger, P., Grevstad, U., Estrup, S., Geisler, A., Vilhelmsen, F., Dahl, J. B., Laier, G. H., Ilfeld, B. M. & Mathiesen, Ole, 2019, In: Regional Anesthesia and Pain Medicine. 44, 3, p. 333-340

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The authors reply

    Estrup, S., Poulsen, L. M., Gögenur, Ismail & Mathiesen, Ole, 2019, In: Critical Care Medicine. 47, 6, p. e532 1 p.

    Research output: Contribution to journalComment/debateResearch

  39. Published

    The effect of remote ischaemic preconditioning on myocardial injury in emergency hip fracture surgery (PIXIE trial): Phase II randomised clinical trial

    Ekeloef, S., Homilius, M., Stilling, M., Ekeloef, P., Koyuncu, S., Münster, A. M. B., Meyhoff, Christian Sylvest, Gundel, O., Holst-Knudsen, J., Mathiesen, Ole & Gögenur, Ismail, 2019, In: The BMJ. 367, l6395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2018
  41. Published

    Cognitive Function 3 and 12 Months After ICU Discharge: A Prospective Cohort Study

    Estrup, S., Kjer, C. K. W., Vilhelmsen, F., Poulsen, L. M., Gögenur, Ismail & Mathiesen, Ole, 2018, In: Critical Care Medicine. 46, 12, p. e1121-e1127

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Delirium and effect of circadian light in the intensive care unit: a retrospective cohort study

    Estrup, S., Kjer, C. K. W., Poulsen, L. M., Gögenur, Ismail & Mathiesen, Ole, 2018, In: Acta Anaesthesiologica Scandinavica. 62, 3, p. 367-375

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Evolution of bias and sample size in postoperative pain management trials after hip and knee arthroplasty

    Karlsen, A. P. H., Dahl, J. B. & Mathiesen, Ole, 2018, In: Acta Anaesthesiologica Scandinavica. 62, 5, p. 666-676 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Haloperidol for delirium in critically ill patients - protocol for a systematic review

    Barbateskovic, M., Kraus, S. R., Collet, M. O., Mathiesen, Ole, Jakobsen, J. C., Perner, Anders & Wetterslev, J., 2018, In: Acta Anaesthesiologica Scandinavica. 62, 5, p. 712-723 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Heterogenic control groups in randomized, controlled, analgesic trials of total hip and knee arthroplasty

    Karlsen, A. P., Mathiesen, Ole & Dahl, J. B., 2018, In: Minerva Anestesiologica. 84, 3, p. 346-362 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Sensory distribution of the lateral femoral cutaneous nerve block - a randomised, blinded trial

    Nersesjan, M., Hägi-Pedersen, Daniel, Andersen, Jakob Hessel, Mathiesen, Ole, Dahl, J. B., Broeng, L. & Thybo, K. H., 2018, In: Acta Anaesthesiologica Scandinavica. 62, 6, p. 863-873 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2017
  48. Published

    Improving Neuromuscular Monitoring and Reducing Residual Neuromuscular Blockade With E-Learning: Protocol for the Multicenter Interrupted Time Series INVERT Study

    Thomsen, J. L. D., Mathiesen, Ole, Hägi-Pedersen, Daniel, Skovgaard, Lene Theil, Østergaard, Doris, Engbaek, J. & Gätke, M. R., 6 Oct 2017, In: JMIR Research Protocols.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Gabapentin in procedure-specific postoperative pain management: preplanned subgroup analyses from a systematic review with meta-analyses and trial sequential analyses

    Fabritius, M. L., Geisler, A., Petersen, P. L., Wetterslev, J., Mathiesen, Ole & Dahl, J. B., 21 Jun 2017, In: B M C Anesthesiology. 17, 20 p., 85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Intraoperative ketamine reduces immediate postoperative opioid consumption after spinal fusion surgery in chronic pain patients with opioid dependency: a randomized, blinded trial

    Nielsen, R. V., Fomsgaard, J. S., Siegel, H., Martusevicius, R., Nikolajsen, L., Dahl, J. B. & Mathiesen, Ole, Mar 2017, In: Pain. 158, 3, p. 463-470 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    An urgent call for improved quality of trial design and reporting in postoperative pain research

    Fabritius, M. L., Wetterslev, J., Dahl, J. B. & Mathiesen, Ole, Jan 2017, In: Acta Anaesthesiologica Scandinavica. 61, 1, p. 8-10 3 p.

    Research output: Contribution to journalEditorialResearch

  52. Published

    Does Dexmedetomidine Have a Perineural Mechanism of Action When Used as an Adjuvant to Ropivacaine? A Paired, Blinded, Randomized Trial in Healthy Volunteers

    Andersen, J. H., Grevstad, U., Siegel, H., Dahl, J. B., Mathiesen, Ole & Jaeger, P., Jan 2017, In: Anesthesiology. 126, 1, p. 66-73 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Low degree of satisfactory individual pain relief in post-operative pain trials

    Geisler, A., Dahl, J. B., Karlsen, A. P. H., Persson, E. & Mathiesen, Ole, Jan 2017, In: Acta Anaesthesiologica Scandinavica. 61, 1, p. 83-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Benefit and harm of pregabalin in acute pain treatment: a systematic review with meta-analyses and trial sequential analyses

    Fabritius, M. L., Strøm, C., Koyuncu, S., Jæger, P., Petersen, P. L., Geisler, A., Wetterslev, J., Dahl, J. B. & Mathiesen, Ole, 2017, In: British Journal of Anaesthesia. 119, 4, p. 775-791

    Research output: Contribution to journalReviewResearchpeer-review

  55. Published

    Clonidine used as a perineural adjuvant to ropivacaine, does not prolong the duration of sensory block when controlling for systemic effects: A paired, blinded, randomized trial in healthy volunteers

    Andersen, Jakob Hessel, Jaeger, P., Sonne, T. L., Dahl, J. B., Mathiesen, Ole & Grevstad, U., 2017, In: PLOS ONE. 12, 9, 12 p., e0181351.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 131852132