Anders Perner

Response

Sivapalan, P. & Perner, Anders, Feb 2024, In: Chest. 165, 2, p. e59-e60 1 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Albumin use in patients with septic shock—Post-hoc analyses of an international randomised fluid trial

Meyhoff, T. S., Granholm, A., Hjortrup, P. B., Sivapalan, P., Lange, Theis, Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander & Perner, Anders, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 3, p. 372-384 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of IV fluid restriction according to site-specific intensity of standard fluid treatment-protocol

Sivapalan, P., Kaas-Hansen, Benjamin Skov, Meyhoff, T. S., Hjortrup, P. B., Kjær, M. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2024, (E-pub ahead of print) In: Acta Anaesthesiologica Scandinavica. 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of a lower versus a higher oxygenation target in intensive care unit patients with chronic obstructive pulmonary disease and acute hypoxaemic respiratory failure: a subgroup analysis of a randomised clinical trial

Nielsen, M. B., Klitgaard, T. L., Weinreich, U. M., Nielsen, F. M., Perner, Anders, Schjørring, O. L. & Rasmussen, B. S., 2024, In: BJA Open. 10, 9 p., 100281.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of sceptical priors on the performance of adaptive clinical trials with binary outcomes

Granholm, A., Lange, Theis, Harhay, M. O., Perner, Anders, Møller, Morten Hylander & Kaas-Hansen, Benjamin Skov, 2024, (E-pub ahead of print) In: Pharmaceutical Statistics. 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Furosemide versus placebo for fluid overload in intensive care patients-The randomised GODIF trial second version: Statistical analysis plan

Wichmann, S., Lange, T., Perner, A., Gluud, C., Itenov, T. S., Berthelsen, R. E., Nebrich, L., Wiis, J., Brøchner, A. C., Nielsen, L. G., Behzadi, M. T., Damgaard, K., Andreasen, A. S., Strand, K., Järvisalo, M., Strøm, T., Eschen, C. T., Vang, M. L., Hildebrandt, T., Andersen, F. H. & 14 others, Sigurdsson, M. I., Thomar, K. M., Thygesen, S. K., Troelsen, T. T., Uusalo, P., Jalkanen, V., Illum, D., Sølling, C., Keus, F., Pfortmueller, C. A., Wahlin, R. R., Ostermann, M., Aneman, A. & Bestle, Morten Heiberg, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 130-136 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Heterogeneity of treatment effect of higher dose dexamethasone by geographic region (Europe vs. India) in patients with COVID-19 and severe hypoxemia – a post hoc evaluation of the COVID STEROID 2 trial

Tirupakuzhi Vijayaraghavan, B. K., Granholm, A., Munch, M. W., Kjær, M. B. N., Møller, M. H., Perner, A., Myatra, S. N., Jha, V., Jha, V., Jha, V., Hammond, N., Micallef, S., Venkatesh, B., Hammond, N., Lange, T., Munch, M. W., Myatra, S. N., Tirupakuzhi Vijayaraghavan, B. K., Saseedharan, S., Benfield, T. & 31 others, Wahlin, R. R., Rasmussen, B. S., Andreasen, Anne Sofie, Poulsen, L. M., Cioccari, L., Khan, M. S., Kapadia, F., Divatia, J. V., Brøchner, A. C., Bestle, Morten Heiberg, Helleberg, Marie, Michelsen, J., Padmanaban, A., Bose, N., Møller, A., Borawake, K., Kristiansen, Klaus Tjelle, Shukla, U., Chew, M. S., Ulrik, Charlotte Suppli, Kjær, M. B. N., Møller, Morten Hylander, Meyhoff, T. S., Vesterlund, G. K., Gluud, C., Lange, Theis, Marcussen, Klaus Vennick, Nielsen, H., Jensen, T. S., Perner, Anders & the COVID-STEROID 2 collaborators, T. C. 2. C., 2024, In: The Lancet Regional Health - Southeast Asia. 20, 8 p., 100293.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term cognitive and pulmonary functions following a lower versus a higher oxygenation target in the HOT-ICU and HOT-COVID trials: A protocol update

Crescioli, E., Riis, J. Ø., Weinreich, U. M., Jensen , Jens-Ulrik Stæhr , Poulsen, L. M., Brøchner, A. C., Lange, Theis, Perner, Anders, Klitgaard, T. L., Schjørring, O. L. & Rasmussen, B. S., 2024, In: Acta Anaesthesiologica Scandinavica. 68, 4, p. 575-578 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium

Mortensen, C. B., Andersen-Ranberg, N. C., Poulsen, L. M., Granholm, A., Rasmussen, B. S., Kjær, M. B. N., Lange, T., Ebdrup, B. H., Collet, M. O., Andreasen, A. S., Bestle, M. H., Uslu, B., Pedersen, H. S., Nielsen, L. G., Hästbacka, J., Jensen, T. B., Damgaard, K., Sommer, T., Morgen, M., Dey, N. & 6 others, Citerio, G., Estrup, S., Egerod, Ingrid Eugenie, Samuelson, K., Perner, Anders & Mathiesen, Ole, 2024, In: Intensive Care Medicine. 50, p. 103–113 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial

Nielsen, F. M., Klitgaard, T. L., Siegemund, M., Laake, J. H., Thormar, K. M., Cole, J. M., Aagaard, S. R., Bunzel, A-M. G., Vestergaard, S. R., Langhoff, P. K., Pedersen, C. H., Hejlesen, J. Ø., Abdelhamid, S., Dietz, A., Gebhard, C. E., Zellweger, N., Hollinger, A., Poulsen, L. M., Weihe, S., Andersen-Ranberg, N. C. & 25 others, Pedersen, U. G., Mathiesen, Ole, Andreasen, Anne Sofie, Brix, H., Thomsen, J. J., Petersen, C. H., Bestle, Morten Heiberg, Wichmann, S., Lund, M. S., Mortensen, K. M., Brand, B. A., Haase, N., Iversen, S. A., Marcussen, Klaus Vennick, Brøchner, A. C., Borup, M., Grøfte, T., Hildebrandt, T., Kjær, M. N., Engstrøm, J., Lange, Theis, Perner, Anders, Schjørring, O. L., Rasmussen, B. S. & HOT-COVID Trial Group, H. T. G., 2024, In: JAMA. 331, 14, p. 1185-1194 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Platelet transfusions in adult thrombocytopenic ICU patients: Protocol for a sub-study of the PLOT-ICU cohort

Anthon, C. T., Pène, F., Perner, Anders, Azoulay, E., Puxty, K., Van De Louw, A., Chawla, S., Castro, P., Povoa, P., Coelho, L., Metaxa, V., Kochanek, M., Liebregts, T., Kander, T., Sivula, M., Møller, Morten Hylander & Russell, Lene, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 3, p. 434-440 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Restrictive versus standard IV fluid therapy in adult ICU patients with septic shock—Bayesian analyses of the CLASSIC trial

Sivapalan, P., Meyhoff, T. S., Hjortrup, P. B., Lange, Theis, Kaas-Hansen, Benjamin Skov, Kjær, M. B. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2024, In: Acta Anaesthesiologica Scandinavica. 68, 2, p. 236-246 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Non-response for health-related quality of life outcomes in ICU patients: A systematic review of the reporting in randomised trials

Kjær, M. B. N., Madsen, M. B., Meier, N., Granholm, A., Møller, Morten Hylander, Egerod, Ingrid Eugenie & Perner, Anders, Aug 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 842-852 11 p.

Research output: Contribution to journal › Review › Research › peer-review

Abnormal serum levels of magnesium, phosphate, and zinc in ICU patients—Characteristics, management, and outcomes: The WhyTrace cohort study

Vesterlund, G. K., Thorsen-Meyer, H. C., Møller, Morten Hylander, Brunak, Søren, Strøm, T., Perner, Anders & Kaas-Hansen, Benjamin Skov, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, p. 925-935 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Albumin administration in septic shock-Protocol for post-hoc analyses of data from a multicentre RCT

Meyhoff, T. S., Granholm, A., Hjortrup, P. B., Sivapalan, P., Lange, Theis, Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 8, p. 1128-1136 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

An overview of methodological considerations regarding adaptive stopping, arm dropping and randomisation in clinical trials

Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Schjørring, O. L., Andersen, L. W., Perner, Anders, Jensen, Aksel Karl Georg & Møller, Morten Hylander, 2023, In: Journal of Clinical Epidemiology. 153, p. 45-54 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association between days alive without life support/out of hospital and health-related quality of life

Granholm, A., Schjorring, O. L., Jensen, Aksel Karl Georg, Kaas-Hansen, Benjamin Skov, Munch, M. W., Klitgaard, T. L., Crescioli, E., Kjaer, M. N., Strom, T., Lange, Theis, Perner, Anders, Rasmussen, B. S. & Møller, Morten Hylander, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 6, p. 762-771 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between enteral nutrition and outcomes in the SUP-ICU trial: Protocol for exploratory post hoc analyses

Borthwick, M., Granholm, A., Marker, S., Krag, M., Lange, Theis, Wise, M. P., Bendel, S., Keus, F., Guttormsen, A. B., Schefold, J. C., Wetterslev, J., Perner, Anders, Møller, Morten Hylander & SUP-ICU investigators, S. I., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 4, p. 481-486 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Atrial Fibrillation (AFIB) in the ICU: Incidence, Risk Factors, and Outcomes: The International AFIB-ICU Cohort Study

Wetterslev, M., Hylander Møller, M., Granholm, A., Hassager, C., Haase, N., Lange, T., Myatra, S. N., Hästbacka, J., Arabi, Y. M., Shen, J., Cronhjort, M., Lindqvist, E., Aneman, A., Young, P. J., Szczeklik, W., Siegemund, M., Koster, T., Aslam, T. N., Bestle, M. H., Girkov, M. S. & 31 others, Kalvit, K., Mohanty, R., Mascarenhas, J., Pattnaik, M., Vergis, S., Haranath, S. P., Shah, M., Joshi, Z., Wilkman, E., Reinikainen, M., Lehto, P., Jalkanen, V., Pulkkinen, A., An, Y., Wang, G., Huang, L., Huang, B., Liu, W., Gao, H., Dou, L., Li, S., Yang, W., Tegnell, E., Perner, Anders, Poulsen, L. M., Hildebrandt, T., Andreasen, Anne Sofie, Kristiansen, Klaus Tjelle, Mohr, T., Møller, Kirsten & the AFIB-ICU collaborators, T. A. C., 2023, In: Critical Care Medicine. 51, 9, p. 1124-1137 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia

Blette, B. S., Granholm, A., Li, F., Shankar-Hari, M., Lange, Theis, Munch, M. W., Møller, Morten Hylander, Perner, Anders & Harhay, M. O., 2023, In: Scientific Reports. 13, 1, 10 p., 6570.

Research output: Contribution to journal › Journal article › Research › peer-review

Clinical progression, disease severity, and mortality among adults hospitalized with COVID-19 caused by the Omicron and Delta SARS-CoV-2 variants: A population-based, matched cohort study

Harboe, Z. B., Roed, C., Holler, J. G., Khan, F. I., Abdulrahman, A. N. A., Mulverstedt, S. L., Lindgaard-Jensen, B., Bertelsen, B. B., Søborg, C., Nielsen, T. L., Hansen, L. V., Madsen, B. L., Browatzki, A., Eiberg, M., Bernhard, P. H., Pedersen, E. M. J., Egelund, G. B., Dungu, A. M., Sejdic, A., Mathiesen, I. H. M. & 56 others, Jespersen, N. Z., Petersen, P. T., Nielsen, L., Jepsen, M. P. G., Pedersen, T. I., Eriksson, R., Seitz-Rasmussen, H. E. S., Bestle, Morten Heiberg, Andersen, H., Skram, U., Skøtt, M. R., Altaraihi, S., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Bagge, K., Jørgensen, K. M., Knudsen, M. J. S., Leineweber, T., Schneider, Uffe Vest, Ahlstrom, M. G., Rytter, S., Le Dous, N., Ravn, P., Reiter, N., Podlekareva, D., Knudsen, A., Johnsen, Stine, Kristensen, Lars Erik Vølund, Leding, C., Hertz, B. B., Benfield, Thomas, Kirk, Ole, Holler, J. G., Ostrowski, Sisse Rye, Sigurdsson, S. T., Perner, Anders, Kirkby, N., Pedersen, M. S., Van Wijhe, M., Simonsen, L., Bager, P. M., Krause, T. G., Voldstedlund, M., Christiansen, L. E., Stegger, M., Cohen, A., Fonager, J., Fomsgaard, A., Legarth, R., Rasmussen, M., Gubbels, S., Wohlfahrt, J., Lillebaek, Troels, Johannesen, C. K., Van Wijhe, M. & Fischer, Thea Kølsen, 2023, In: PLoS ONE. 18, 4 , 15 p., e0282806.

Research output: Contribution to journal › Journal article › Research › peer-review

Dexmedetomidine for the prevention of delirium in adults admitted to the intensive care unit or post-operative care unit: A systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis

Maagaard, M., Barbateskovic, M., Andersen-Ranberg, N. C., Kronborg, J. R., Chen, Y. X., Xi, H. H., Perner, Anders & Wetterslev, J., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 4, p. 382-411 30 p.

Research output: Contribution to journal › Review › Research › peer-review

ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

the European Society of Intensive Care Medicine Taskforce on ARDS, T. E. S. O. I. C. M. T. O. A., 2023, In: Intensive Care Medicine. 49, 7, p. 727-759 33 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of 12 mg vs. 6 mg dexamethasone on thromboembolism and bleeding in patients with critical COVID-19 - a post hoc analysis of the randomized, blinded COVID STEROID 2 trial

Jonmarker, S., Alarcón, F., Litorell, J., Granholm, A., Alm, E. J., Chew, M., Russell, Lene, Weihe, S., Madsen, Emilie, Meier, N., Leistner, J. W., Mårtensson, J., Hollenberg, J., Perner, Anders, Kjær, M. B. N., Munch, M. W., Dahlberg, M., Cronhjort, M. & Wahlin, R. R., 2023, In: Annals of Intensive Care. 13, 1, 10 p., 12.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of duration of follow-up and lag in data collection on the performance of adaptive clinical trials

Granholm, A., Lange, Theis, Harhay, M. O., Jensen, Aksel Karl Georg, Perner, Anders, Møller, Morten Hylander & Kaas-Hansen, Benjamin Skov, 2023, In: Pharmaceutical Statistics. 23, 2, p. 138-150 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of magnesium, phosphate, or zinc supplementation in intensive care unit patients—A systematic review and meta-analysis

Vesterlund, G. K., Jensen, T. S., Ellekjaer, K. L., Møller, Morten Hylander, Thomsen, Thordis & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 3, p. 264-276

Research output: Contribution to journal › Review › Research › peer-review

Functional and cognitive rehabilitation interventions during intensive care admission: A protocol for a systematic integrative review

Collet, Marie Oxenbøll, Laerkner, E., Jensen, J., Egerod, Ingrid Eugenie, Christensen, Jan, Jørgensen, N. K., Kjærgaard, R. S., Olausson, S., Wøien, H., Lange, Theis, Nielsen, A. H., Kjær, M. B. N., Bruun, C. R. L. & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 5, p. 670-674 5 p.

Research output: Contribution to journal › Review › Research › peer-review

Goal-directed fluid removal with furosemide versus placebo in intensive care patients with fluid overload: A randomised, blinded trial (GODIF trial—First version)

Wichmann, S., Schønemann-Lund, M., Perner, Anders, Itenov, Theis Skovsgaard, Lange, Theis, Gluud, C., Berthelsen, R. E., Brøchner, A. C., Wiis, J. & Bestle, Morten Heiberg, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 4, p. 470-478 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Haloperidol for the treatment of delirium in critically ill patients: an updated systematic review with meta-analysis and trial sequential analysis

Andersen-Ranberg, N. C., Barbateskovic, M., Perner, Anders, Collet, Marie Oxenbøll, Musaeus Poulsen, L., van der Jagt, M., Smit, L., Wetterslev, J., Mathiesen, Ole & Maagaard, M., 2023, In: Critical Care. 27, 1, 14 p., 329.

Research output: Contribution to journal › Journal article › Research › peer-review

Haloperidol vs. placebo for the treatment of delirium in ICU patients: a pre-planned, secondary Bayesian analysis of the AID–ICU trial

Andersen-Ranberg, N. C., Poulsen, L. M., Perner, Anders, Hästbacka, J., Morgan, M., Citerio, G., Collet, Marie Oxenbøll, Weber, S. O., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, B., Pedersen, H. S., Nielsen, L. G., Damgaard, K., Jensen, T. B., Sommer, T., Dey, N., Mathiesen, Ole & Granholm, A., 2023, In: Intensive Care Medicine. 49, p. 411–420 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Health-related quality of life trajectories in critical illness: Protocol for a Monte Carlo simulation study

Kaas-Hansen, Benjamin Skov, Kjaer, M. N., Møller, Morten Hylander, Jensen, Aksel Karl Georg, Larsen, M. E., Cuthbertson, B. H., Perner, Anders & Granholm, A., 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Heterogeneous treatment effects of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia—Post hoc exploratory analyses of the COVID STEROID 2 trial

Granholm, A., Munch, M. W., Andersen-Ranberg, N., Myatra, S. N., Vijayaraghavan, B. K. T., Venkatesh, B., Jha, V., Wahlin, R. R., Jakob, S. M., Cioccari, L., Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 2, p. 195-205 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Issuing of isotonic crystalloid solutions to Danish public hospitals in 2021—A retrospective nationwide observational study

Ellekjaer, K. L., Perner, Anders, Bruun Svan, K. & Møller, Morten Hylander, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 2, p. 177-184 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term effects of restriction of intravenous fluid in adult ICU patients with septic shock

Kjær, M. B. N., Meyhoff, T. S., Sivapalan, P., Granholm, A., Hjortrup, P. B., Madsen, M. B., Møller, M. H., Egerod, I., Wetterslev, J., Lange, T., Cronhjort, M., Laake, J. H., Jakob, S. M., Nalos, M., Ostermann, M., Gould, D., Cecconi, M., Malbrain, M. L. N. G., Ahlstedt, C., Kiel, L. B. & 41 others, Bestle, Morten Heiberg, Nebrich, L., Hildebrandt, T., Russell, Lene, Vang, M., Rasmussen, M. L., Sølling, C., Brøchner, A. C., Krag, M., Pfortmueller, C., Kriz, M., Siegemund, M., Albano, G., Aagaard, S. R., Bundgaard, H., Crone, V., Wichmann, S., Johnstad, B., Martin, Y. K., Seidel, P., Mårtensson, J., Hollenberg, J., Wistrand, M., Donati, A., Barbara, E., Karvunidis, T., Hollinger, A., Carsetti, A., Lumlertgul, N., Joelsson-Alm, E., Lambiris, N., Aslam, T. N., Friberg, F. F., Vesterlund, G. K., Mortensen, C. B., Vestergaard, S. R., Caspersen, S. F., Jensen, D. B., Borup, M., Rasmussen, B. S. & Perner, Anders, 2023, In: Intensive Care Medicine. 49, p. 820–830 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term outcomes in COVID-19 patients admitted to intensive care in Denmark: A nationwide observational study

Meier, N., Perner, A., Plovsing, R., Christensen, S., Poulsen, L. M., Brøchner, A. C., Rasmussen, B. S., Helleberg, M., Jensen, J. U. S., Andersen, L. P. K., Siegel, H., Ibsen, M., Jørgensen, V. L., Winding, R., Iversen, S., Pedersen, H. P., Sølling, C., Garcia, R. S., Michelsen, J., Mohr, T. & 16 others, Michagin, G., Espelund, U. S., Bundgaard, H., Kirkegaard, L., Smitt, M., Sigurdsson, S., Buck, D. L., Ribergaard, N., Pedersen, H. S., Toft, M. H., Jonassen, T. B., Mølgaard Nielsen, F., Madsen, E. K., Haberlandt, T. N., Bredahl, L. S. & Haase, N., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 9, p. 1239-1248 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lower versus higher oxygenation targets in hypoxaemic ICU patients after cardiac arrest

Crescioli, E., Lass Klitgaard, T., Perner, Anders, Lilleholt Schjørring, O. & Steen Rasmussen, B., 2023, In: Resuscitation. 188, 109838.

Research output: Contribution to journal › Journal article › Research › peer-review

Patient and public involvement in contemporary large intensive care trials: A meta-epidemiological study

Estrup, S., Barot, E., Mortensen, C. B., Anthon, C. T., Crescioli, E., Kjær, M. B. N., Vesterlund, G. K., Bruun, C. R. L., Collet, Marie Oxenbøll, Rasmussen, B. S., Sivapalan, P., Poulsen, L. M., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 3, p. 256-263 8 p.

Research output: Contribution to journal › Review › Research › peer-review

Piperacillin/tazobactam versus carbapenems in patients with severe bacterial infections: A systematic review with meta-analysis

Munch, M. W., Granholm, A., Jonsson, A. B., Sjövall, F., Helleberg, Marie, Hertz, Frederik Boëtius, Andersen, J. S., Steensen, M., Achiam, Michael Patrick, Perner, Anders & Møller, Morten Hylander, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 7, 16 p.

Research output: Contribution to journal › Review › Research › peer-review

Platform trials: Platformsforsøg

Perner, A., Kjær, M. B. N., Thorsen-Meyer, H. C., Kaas-Hansen, B. S., Munch, M. W., Collet, M. O., Bruun, C. R., Jensen, A. K., Lange, T., Albertsen, T., Pedersen, C. D., Poulsen, L. M., Mathiesen, O., Brøchner, A. C., Strøm, T., Andersen, L. W., Christensen, S., Rasmussen, B. S., Schjørring, O. L., Maagaard, M. & 2 others, Møller, Morten Hylander & Granholm, A., 2023, In: Ugeskrift for Laeger. 185, 41, 10 p.

Research output: Contribution to journal › Review › Research › peer-review

Protocol for a systematic review and meta-analysis assessing conservative versus liberal intravenous fluid administration in patients with sepsis or septic shock at risk of fluid overload

Bharwani, A., Pérez, M. L., Englesakis, M., Meyhoff, T. S., Perner, Anders, Sivapalan, P. & Wilcox, M. E., 2023, In: BMJ Open. 13, 5, 4 p., e069601.

Research output: Contribution to journal › Journal article › Research › peer-review

Real-world causal evidence for planned predictive enrichment in critical care trials: A scoping review

Kaas-Hansen, Benjamin Skov, Granholm, A., Sivapalan, P., Anthon, C. T., Schjørring, O. L., Maagaard, M., Kjaer, M. N., Mølgaard, J., Ellekjaer, K. L., Fagerberg, S. K., Lange, Theis, Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 16-25 10 p.

Research output: Contribution to journal › Review › Research › peer-review

Routine Versus On-Demand Blood Sampling in Critically Ill Patients: A Systematic Review∗

Hjortso, C. J. S., Møller, Morten Hylander, Perner, Anders & Brochner, A. C., 2023, In: Critical Care Medicine. 51, 6, p. 717-730 14 p.

Research output: Contribution to journal › Review › Research › peer-review

Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)

Anthon, C. T., Pène, F., Perner, A., Azoulay, E., Puxty, K., Van De Louw, A., Barratt-Due, A., Chawla, S., Castro, P., Póvoa, P., Coelho, L., Metaxa, V., Kochanek, M., Liebregts, T., Kander, T., Hästbacka, J., Andreasen, J. B., Péju, E., Nielsen, L. B., Hvas, C. L. & 101 others, Dufranc, E., Canet, E., Lundqvist, L., Wright, C. J., Schmidt, J., Uhel, F., Ait-Oufella, H., Krag, M., Cos Badia, E., Díaz-Lagares, C., Menat, S., Voiriot, G., Clausen, N. E., Lorentzen, K., Kvåle, R., Hildebrandt, T., Holten, A. R., Strand, K., Tzalavras, A., Bestle, Morten Heiberg, Klepstad, P., Fernandez, S., Vimpere, D., Costa, C., Graça, C., Lueck, C., Juhl, C. S., Costa, C., Bådstøløkken, P. M., Miranda, T., Lêdo, L. S. A., Sousa Torres, J. C., Granholm, A., Møller, Morten Hylander, Russell, Lene, Khalil, A., Yehia, A., Salem, H., Farahat, H., Sudevan, M., Biggart, M., Fatima, N., Elkhonezy, M., Bunzel, A. M., Siegumfeldt, R. M., Vestergaard, S. R., Pelle, J., Lê, M. P., Vigneron, C., Bertrix, M., Cirera, P., Laghlam, D., Bredin, S., Marin, N., Toppenberg, M., Benelli, B., Seguin, A., Garret, C., Guillotin, F., Blonz, G., Lascarrou, J. B., Lemarie, J., Desmedt, L., Agbakou, M., Carpentier, M., Martin, M., Benkalfate, N., Zambon, O., Decamps, P., Wilquin, P. L., Benguerfi, S., Gardner, J., Remor, N., Carr, S., Yang, G., Gernez, C., Thiry, I., Missri, L., Denneborg, M. K. G., Brown, K., Casares, V., Sivula, M., Lappi, E., Pettilä, L., Heinonen, J., Saario, M., Mecheri, M. K., Elabbadi, A., Desnos, C., Lafarge, A., Mghirbi, O., Sjøbø, B., Christoffersen, C., Bestle, F. H., Lemos, C., Gonçalves, C. V., Jacinto, N. M. B., Anselmo, M. P., Hoeper, M. M., Hoff, M. & Simões Freire, P. M., 2023, In: Intensive Care Medicine. 49, 11, p. 1327-1338 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Thromboembolic and bleeding events in ICU patients with COVID-19: A nationwide, observational study

Russell, L., Weihe, S., Madsen, E. K., Hvas, C. L., Leistner, J. W., Michelsen, J., Brøchner, A. C., Bastiansen, A., Mølgaard Nielsen, F., Meier, N., Andreasen, A. S., Ribergaard, NE., Rasmussen, B. S., Sølling, C. G., Buck, D. L., Bundgaard, H., Pedersen, H. S., Darfelt, I. S., Poulsen, L. M., Ibsen, M. & 9 others, Plovsing, Ronni Thermann Reitz, Sigurdsson, S. T., Iversen, S., Hildebrandt, T., Mohr, T., Espelund, U. S., Jørgensen, Vibeke Renée Lind, Haase, N. & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 67, 1, p. 76-85 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Use of days alive without life support and similar count outcomes in randomised clinical trials – an overview and comparison of methodological choices and analysis methods

Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Munch, M. W., Harhay, M. O., Zampieri, F. G., Perner, Anders, Møller, Morten Hylander & Jensen, Aksel Karl Georg, 2023, In: BMC Medical Research Methodology. 23, 1, 12 p., 139.

Research output: Contribution to journal › Journal article › Research › peer-review

Use of prokinetic agents in hospitalised adult patients: a scoping review

Crone, V., Møller, Morten Hylander, Bækgaard, E. S., Perner, Anders, Bytzer, Peter, Alhazzani, W. & Krag, M., 2023, In: Acta Anaesthesiologica Scandinavica. 67, 5, p. 588-598

Research output: Contribution to journal › Review › Research › peer-review

Causal inference for planning randomised critical care trials: protocol for a scoping review

Kaas-Hansen, Benjamin Skov, Granholm, A., Anthon, C. T., Kjær, M. N., Sivapalan, P., Maagaard, M., Schjørring, O. L., Fagerberg, S. K., Ellekjær, K. L., Mølgaard, J., Ekstrøm, Claus Thorn, Møller, Morten Hylander & Perner, Anders, Oct 2022, In: Acta Anaesthesiologica Scandinavica. 66, 10, p. 1274–1278 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients (REFACED Sepsis)-protocol for a multicenter, randomized, clinical, proof-of-concept trial

Jessen, M. K., Andersen, L. W., Thomsen, M. H., Kristensen, P., Hayeri, W., Hassel, R. E., Perner, Anders, Petersen, J. A. K. & Kirkegaard, H., 29 Mar 2022, In: Pilot and Feasibility Studies. 8, 1, 8 p., 75.

Research output: Contribution to journal › Journal article › Research › peer-review

A descriptive study of the surge response and outcomes of ICU patients with COVID-19 during first wave in Nordic countries

Chew, M. S., Kattainen, S., Haase, N., Buanes, E. A., Kristinsdottir, L. B., Hofsø, K., Laake, J. H., Kvåle, R., Hästbacka, J., Reinikainen, M., Bendel, S., Varpula, T., Walther, S., Perner, Anders, Flaatten, H. K. & Sigurdsson, M. I., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 1, p. 56-64 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Acetate- versus lactate-buffered crystalloid solutions: A systematic review with meta-analysis and trial sequential analysis

Ellekjaer, K. L., Perner, Anders, Sivapalan, P. & Møller, Morten Hylander, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 7, p. 782-794

Research output: Contribution to journal › Review › Research › peer-review

Agents intervening against delirium in the intensive care unit trial — Protocol for a secondary Bayesian analysis

Andersen-Ranberg, N., Poulsen, L. M., Perner, Anders, Hästbacka, J., Morgan, M. P. G., Citerio, G., Oxenbøll-Collet, M., Weber, S., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, B., Pedersen, H. B. S., Nielsen, L. G., Damgaard, K., Jensen, T. B., Sommer, T., Dey, N., Mathiesen, Ole & Granholm, A., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 7, p. 898-903

Research output: Contribution to journal › Journal article › Research › peer-review

Changes over time in characteristics, resource use and outcomes among ICU patients with COVID-19—A nationwide, observational study in Denmark

Haase, N., Plovsing, R., Christensen, S., Poulsen, L. M., Brøchner, A. C., Rasmussen, B. S., Helleberg, M., Jensen, J. U. S., Andersen, L. P. K., Siegel, H., Ibsen, M., Jørgensen, V. L., Winding, R., Iversen, S., Pedersen, H. P., Madsen, J., Sølling, C., Garcia, R. S., Michelsen, J., Mohr, T. & 19 others, Michagin, G., Espelund, U. S., Bundgaard, H., Kirkegaard, L., Smitt, M., Buck, D. L., Ribergaard, N. E., Pedersen, H. S., Christensen, B. V., Nielsen, L. P., Clapp, E., Jonassen, T. B., Weihe, S., la Cour, K., Nielsen, F. M., Madsen, E. K., Haberlandt, T. N., Meier, N. & Perner, Anders, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 8, p. 987-995 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Choice of priors: how much scepticism is appropriate?

Granholm, A., Munch, M. W., Møller, Morten Hylander, Lange, Theis & Perner, Anders, 2022, In: Intensive Care Medicine. 48, p. 372–373 2 p.

Research output: Contribution to journal › Letter › Research › peer-review

Conservative vs. liberal fluid therapy in septic shock - Protocol for secondary Bayesian analyses of the CLASSIC trial

Sivapalan, P., Meyhoff, T. S., Hjortrup, P. B., Lange, Theis, Møller, Morten Hylander, Perner, Anders & Granholm, A., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 6, p. 767-771 5 p.

Research output: Contribution to journal › Review › Research › peer-review

Development of a core outcome set for general intensive care unit patients - A protocol

Kjær, M. N., Granholm, A., Vesterlund, G. K., Estrup, S., Sivapalan, P., Bruun, C. R. L., Mortensen, C. B., Poulsen, L. M., Møller, Morten Hylander, Christensen, S., Strøm, T., Laerkner, E., Brøchner, A. C., Rasmussen, B. S., Vestergaard, S. R., Barot, E., Madsen, M. B., Egerod, Ingrid Eugenie, Perner, Anders & Collet, M. O., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 3, p. 415-424 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Development of a core outcome set for general intensive care unit patients - Need for a broader context - Author's reply

Kjær, M. N., Granholm, A., Perner, Anders & Collet, M. O., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 541-542 2 p.

Research output: Contribution to journal › Letter › Research › peer-review

Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial

Granholm, A., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Kjaer, M-B. N., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Moller, M. H., Benfield, T., Venkatesh, B., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, V. & 26 others, Kristiansen, Klaus Tjelle, Ulrik, Charlotte Suppli, Jorgensen, V. L., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Poulsen, L. M., Rasmussen, B. S., Brochner, A. C., Strom, T., Moller, A., Khan, M. S., Padmanaban, A., Divatia, J. V., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Wamberg, C. A., Gluud, C., Lange, Theis & Perner, Anders, 2022, In: Intensive Care Medicine. 48, p. 45–55 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dexamethasone and Number of Days Alive Without Life Support in Adults with COVID-19 and Severe Hypoxemia - Reply

Munch, M. W., Granholm, A. & Perner, Anders, 2022, In: JAMA - Journal of the American Medical Association. 327, 7, p. 683 1 p.

Research output: Contribution to journal › Letter › Research › peer-review

Discrete-time survival analysis in the critically ill: a deep learning approach using heterogeneous data

Thorsen-Meyer, H., Placido, Davide, Kaas-Hansen, Benjamin Skov, Nielsen, A. P., Lange, Theis, Nielsen, A. B., Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Belling, K., Perner, Anders & Brunak, Søren, 2022, In: npj Digital Medicine. 5, 10 p., 142.

Research output: Contribution to journal › Journal article › Research › peer-review

Goal directed fluid removal with furosemide versus placebo in intensive care patients with fluid overload: A trial protocol for a randomised, blinded trial (GODIF trial)

Wichmann, S., Itenov, T. S., Berthelsen, R. E., Lange, T., Perner, A., Gluud, C., Lawson-Smith, P., Nebrich, L., Wiis, J., Brøchner, A. C., Hildebrandt, T., Behzadi, M. T., Strand, K., Andersen, F. H., Strøm, T., Järvisalo, M., Damgaard, K. A. J., Vang, M. L., Wahlin, R. R., Sigurdsson, M. I. & 4 others, Thormar, K. M., Ostermann, M., Keus, F. & Bestle, Morten Heiberg, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 9, p. 1138-1145 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Haloperidol for the Treatment of Delirium in ICU Patients

Andersen-Ranberg, N. C., Poulsen, L. M., Perner, A., Wetterslev, J., Estrup, S., Haestbacka, J., Morgan, M., Citerio, G., Caballero, J., Lange, T., Kjaer, M-B. N., Ebdrup, B. H., Engstrom, J., Olsen, M. H., Oxenboll Collet, M., Mortensen, C. B., Weber, S-O., Andreasen, A. S., Bestle, M. H., Uslu, B. & 28 others, Scharling Pedersen, H., Gramstrup Nielsen, L., Toft Boesen, H. C., Jensen, J. V., Nebrich, L., La Cour, K., Laigaard, J., Haurum, C., Olesen, M. W., Overgaard-Steensen, C., Westergaard, B., Brand, B. A., Kingo Vesterlund, G., Thornberg Kyhnauv, P., Mikkelsen, V. S., Hyttel-Sorensen, S., de Haas, I., Aagaard, S. R., Nielsen, L. O., Eriksen, A. S., Rasmussen, B. S., Brix, H., Hildebrandt, T., Schonemann-Lund, M., Fjeldsoe-Nielsen, H., Kuivalainen, A., Mathiesen, Ole & AID ICU Trial Grp, 2022, In: New England Journal of Medicine. 387, 20, p. 2425-2435 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Health-related quality of life and days alive without life support or out of hospital: protocol

Granholm, A., Schjørring, O. L., Jensen, Aksel Karl Georg, Kaas-Hansen, Benjamin Skov, Munch, M. W., Klitgaard, T. L., Crescioli, E., Kjaer, M. N., Strøm, T., Perner, Anders, Rasmussen, B. S. & Møller, Morten Hylander, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 2, p. 295-301 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Higher versus lower oxygenation targets in COVID-19 patients with severe hypoxaemia (HOT-COVID) trial: Protocol for a secondary Bayesian analysis

Mølgaard Nielsen, F., Lass Klitgaard, T., Granholm, A., Lange, Theis, Perner, Anders, Lilleholt Schjørring, O. & Steen Rasmussen, B., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 3, p. 408-414

Research output: Contribution to journal › Journal article › Research › peer-review

Infection control in the intensive care unit: expert consensus statements for SARS-CoV-2 using a Delphi method

Nasa, P., Azoulay, E., Chakrabarti, A., Divatia, J. V., Jain, R., Rodrigues, C., Rosenthal, V. D., Alhazzani, W., Arabi, Y. M., Bakker, J., Bassetti, M., De Waele, J., Dimopoulos, G., Du, B., Einav, S., Evans, L., Finfer, S., Guérin, C., Hammond, N. E., Jaber, S. & 23 others, Kleinpell, R. M., Koh, Y., Kollef, M., Levy, M. M., Machado, F. R., Mancebo, J., Martin-Loeches, I., Mer, M., Niederman, M. S., Pelosi, P., Perner, Anders, Peter, J. V., Phua, J., Piquilloud, L., Pletz, M. W., Rhodes, A., Schultz, M. J., Singer, M., Timsit, J. F., Venkatesh, B., Vincent, J. L., Welte, T. & Myatra, S. N., 2022, In: The Lancet Infectious Diseases. 22, 3, p. e74-e87

Research output: Contribution to journal › Review › Research › peer-review

Interactions in clinical trials: Protocol and statistical analysis plan for an explorative study of four randomized ICU trials on use of pantoprazole, oxygenation targets, haloperidol and intravenous fluids

Schjørring, O. L., Lange, Theis, Krag, M., Andersen-Ranberg, N. C., Meyhoff, T. S., Marker, S., Klitgaard, T. L., Estrup, S., Møller, Morten Hylander, Rasmussen, B. S., Poulsen, L. M. & Perner, Anders, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 1, p. 156-162 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term cognitive and functional status in Danish ICU patients with COVID-19

Weihe, S., Mortensen, C. B., Haase, N., Andersen, L. P. K., Mohr, T., Siegel, H., Ibsen, M., Jørgensen, V. R. L., Buck, D. L., Pedersen, H. B. S., Pedersen, H. P., Iversen, S., Ribergaard, N., Rasmussen, B. S., Winding, R., Espelund, U. S., Bundgaard, H., Sølling, C. G., Christensen, S., Garcia, R. S. & 7 others, Brøchner, A. C., Michelsen, J., Michagin, G., Kirkegaard, L., Perner, Anders, Mathiesen, Ole & Poulsen, L. M., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 8, p. 978-986 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term cognitive and pulmonary functions following a lower versus a higher oxygenation target in the HOT-ICU trial: protocol and statistical analysis plan

Crescioli, E., Riis, J., Weinreich, U. M., Jensen , Jens-Ulrik Stæhr , Poulsen, L. M., Brøchner, A. C., Lange, Theis, Perner, Anders, Klitgaard, T. L., Schjørring, O. L. & Rasmussen, B. S., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 2, p. 282-287 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term mortality and health-related quality of life in the COVID STEROID trial

Munch, M. W., Granholm, A., Kjær, M. N., Aksnes, T. S., Sølling, C. G., Christensen, S. & Perner, Anders, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 543-545 3 p.

Research output: Contribution to journal › Letter › Research › peer-review

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia

Crescioli, E., Klitgaard, T. L., Poulsen, L. M., Brand, B. A., Siegemund, M., Grøfte, T., Keus, F., Pedersen, U. G., Bäcklund, M., Karttunen, J., Morgan, M., Ciubotariu, A., Bunzel, A-M. G., Vestergaard, S. R., Jensen, N. M., Jensen, T. S., Kjær, M-B. N., Jensen, A. K. G., Lange, T., Wetterslev, J. & 3 others, Perner, Anders, Schjørring, O. L. & Rasmussen, B. S., 2022, In: Intensive Care Medicine. 48, 6, p. 714–722 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia

Granholm, A., Kjær, M-B. N., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Møller, M. H., Benfield, T., Venkatesh, B., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, V. & 29 others, Kristiansen, Klaus Tjelle, Ulrik, Charlotte Suppli, Jørgensen, V. L., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Poulsen, L. M., Rasmussen, B. S., Brochner, A. C., Strøm, T., Møller, A., Khan, M. S., Padmanaban, A., Divatia, J. V., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Wamberg, C. A., Bose, N., Shah, M. S., Darfelt, I. S., Gluud, C., Lange, Theis & Perner, Anders, 2022, In: Intensive Care Medicine. 48, 5, p. 580–589 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Loop diuretics in adult intensive care patients with fluid overload: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

Wichmann, S., Barbateskovic, M., Liang, N., Itenov, Theis Skovsgaard, Berthelsen, R. E., Lindschou, J., Perner, Anders, Gluud, C. & Bestle, Morten Heiberg, 2022, In: Annals of Intensive Care. 12, 1, 16 p., 52.

Research output: Contribution to journal › Review › Research › peer-review

Lower versus higher oxygenation targets in critically ill patients with severe hypoxaemia: secondary Bayesian analysis to explore heterogeneous treatment effects in the Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU) trial

Klitgaard, T. L., Schjørring, O. L., Lange, Theis, Møller, Morten Hylander, Perner, Anders, Rasmussen, B. S. & Granholm, A., 2022, In: British Journal of Anaesthesia. 128, 1, p. 55-64 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Oxygenation targets in ICU patients with COVID-19: a post-hoc sub-group analysis of the HOT-ICU trial

Rasmussen, B. S., Klitgaard, T. L., Perner, A., Brand, B. A., Hildebrandt, T., Siegemund, M., Hollinger, A., Aagaard, S. R., Bestle, M. H., Marcussen, K. V., Brøchner, A. C., Sølling, C. G., Poulsen, L. M., Laake, J. H., Aslam, T. N., Bäcklund, M., Okkonen, M., Morgan, M., Sharman, M., Lange, T. & 2 others, Wetterslev, J. & Schjørring, O. L., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 1, p. 76-84 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Patient-Important Outcomes Other Than Mortality in Contemporary ICU Trials: A Scoping Review

Granholm, A., Anthon, C. T., Kjær, M. N., Maagaard, M., Kaas-Hansen, Benjamin Skov, Sivapalan, P., Schjørring, O. L., Andersen, L. W., Mathiesen, Ole, Strøm, T., Jensen, Aksel Karl Georg, Perner, Anders & Møller, Morten Hylander, 2022, In: Critical Care Medicine. 50, 10, p. e759-e771 13 p.

Research output: Contribution to journal › Review › Research › peer-review

Platelet transfusions and thrombocytopenia in intensive care units: Protocol for an international inception cohort study (PLOT-ICU)

Anthon, C. T., Pène, F., Perner, Anders, Azoulay, E., Puxty, K., Van De Louw, A., Barratt-Due, A., Chawla, S., Castro, P., Povoa, P., Coelho, L., Metaxa, V., Munshi, L., Kochanek, M., Liebregts, T., Kander, T., Hästbacka, J., Møller, Morten Hylander, Russell, Lene & PLOT-ICU Investigators and the Nine-I Study Group, P. I. A. T. N. S. G., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 9, p. 1146-1155 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Prophylactic platelet transfusions versus no prophylaxis in hospitalized patients with thrombocytopenia: A systematic review with meta‐analysis

Anthon, C. T., Granholm, A., Sivapalan, P., Zellweger, N., Pène, F., Puxty, K., Perner, Anders, Møller, Morten Hylander & Russell, Lene, 2022, In: Transfusion. 62, 10, p. 2117-2136

Research output: Contribution to journal › Review › Research › peer-review

Prostacyclin in Mechanically Ventilated Patients with COVID-19 and Severe Endotheliopathy: A Multicenter, Randomized, Clinical Trial

Johansson, P. I., Søe-Jensen, P., Bestle, Morten Heiberg, Clausen, N. E., Kristiansen, Klaus Tjelle, Lange, Theis, Stensballe, J. & Perner, Anders, 2022, In: American Journal of Respiratory and Critical Care Medicine. 205, 3, p. 324-329 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Public versus patient health preferences: Protocol for a study to elicit EQ-5D-5L health state valuations for patients who have survived a stay in intensive care

Halling, C. M. B., Gudex, C., Perner, Anders, Jensen, C. E. & Gyrd-Hansen, D., 2022, In: BMJ Open. 12, 5, e058500.

Research output: Contribution to journal › Journal article › Research › peer-review

Randomised clinical trials in critical care: past, present and future

Granholm, A., Alhazzani, W., Derde, L. P. G., Angus, D. C., Zampieri, F. G., Hammond, N. E., Sweeney, R. M., Myatra, S. N., Azoulay, E., Rowan, K., Young, P. J., Perner, Anders & Møller, Morten Hylander, 2022, In: Intensive Care Medicine. 48, 2, p. 164-178

Research output: Contribution to journal › Review › Research › peer-review

Restriction of Intravenous Fluid in ICU Patients with Septic Shock

Meyhoff, T. S., Hjortrup, P. B., Wetterslev, J., Sivapalan, P., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M., Pettila, V., Møller, M. H., Kjaer, M-B. N., Lange, T., Overgaard-Steensen, C., Brand, B. A., Winther-Olesen, M., White, J. O., Quist, L. & 48 others, Westergaard, B., Jonsson, A. B., Hjortso, C. J. S., Meier, N., Jensen, T. S., Engstrom, J., Nebrich, L., Andersen-Ranberg, N. C., Jensen, J. V., Joseph, N. A., Poulsen, L. M., Herlov, L. S., Solling, C. G., Pedersen, S. K., Knudsen, K. K., Straarup, T. S., Vang, M. L., Bundgaard, H., Rasmussen, B. S., Aagaard, S. R., Hildebrandt, T., Russell, Lene, Bestle, Morten Heiberg, Schonemann-Lund, M., Brochner, A. C., Elvander, C. F., Hoffmann, S. K. L., Rasmussen, M. L., Martin, Y. K., Friberg, F. F., Seter, H., Aslam, T. N., Adnoy, S., Seidel, P., Strand, K., Johnstad, B., Joelsson-Alm, E., Christensen, J., Ahlstedt, C., Pfortmueller, C. A., Siegemund, M., Greco, M., Radej, J., Kriz, M., Gould, D. W., Rowan, K. M., Mouncey, P. R. & Perner, Anders, 2022, In: New England Journal of Medicine. 386, p. 2459-2470 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Restriction of Intravenous Fluid in ICU Patients with Septic Shock. Reply

Meyhoff, T. S., Sivapalan, P. & Perner, Anders, 2022, In: The New England Journal of Medicine. 387, 9, p. 857 1 p.

Research output: Contribution to journal › Comment/debate › Research

Restrictive fluids versus standard care in adults with sepsis in the emergency department (REFACED): A multicenter, randomized feasibility trial

Jessen, M. K., Andersen, L. W., Thomsen, M. H., Kristensen, P., Hayeri, W., Hassel, R. E., Messerschmidt, T. G., Sølling, C. G., Perner, Anders, Petersen, J. A. K. & Kirkegaard, H., 2022, In: Academic Emergency Medicine. 29, 10, p. 1172-1184 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The effect of prostacyclin infusion on markers of endothelial activation and damage in mechanically ventilated patients with SARS-CoV-2 infection

Vigstedt, M., Søe-Jensen, P., Bestle, Morten Heiberg, Clausen, N. E., Kristiansen, Klaus Tjelle, Lange, Theis, Stensballe, J., Perner, Anders & Jo­hans­son, Pär In­ge­mar , 2022, In: Journal of Critical Care. 69, 154010.

Research output: Contribution to journal › Journal article › Research › peer-review

The effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding: a secondary analysis of the SUP-ICU trial

Halling, C. M. B., Møller, Morten Hylander, Marker, S., Krag, M., Kjellberg, J., Perner, Anders & Gyrd-Hansen, D., 2022, In: Intensive Care Medicine. 48, 4, p. 426-434

Research output: Contribution to journal › Journal article › Research › peer-review

Transfusion practice in the bleeding critically ill: An international online survey—The TRACE-2 survey

de Bruin, S., Eggermont, D., van Bruggen, R., de Korte, D., Scheeren, T. W. L., Bakker, J., Vlaar, A. P. J., Abbasciano, R. G., Antonelli, M., Aubron, C., van Baarle, F. E. H. P., Cecconi, M., Dionne, J. C., Duranteau, J., Gyatt, G., Hunt, B. J., Juffermans, N. P., Lance, M., Meier, J., Muller, M. C. A. & 8 others, Murphy, G. J., Nielsen, N., Oczkowski, S. J., Perner, Anders, Raasveld, S. J., Schöchel, H., Wijnberge, M. & Cardiovascular Dynamics Section and Transfusion Task Force of the ESICM, C. D. S. A. T. T. F. O. T. E., 2022, In: Transfusion. 62, 2, p. 324-335 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Treatments of new-onset atrial fibrillation in critically ill patients: a systematic review with meta-analysis

Wetterslev, M., Karlsen, Anders, Granholm, A., Haase, N., Hassager, Christian, Møller, Morten Hylander & Perner, Anders, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 432-446 15 p.

Research output: Contribution to journal › Review › Research › peer-review

Use of prokinetic agents in hospitalised adult patients: Protocol for a scoping review

Crone, V., Møller, Morten Hylander, Perner, Anders, Alhazzani, W. & Krag, M., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 8, p. 1024-1026

Research output: Contribution to journal › Review › Research › peer-review

Using machine learning for predicting intensive care unit resource use during the COVID-19 pandemic in Denmark

Lorenzen, S. S., Nielsen, Mads, Jimenez-Solem, E., Petersen, Tonny Studsgaard, Perner, Anders, Thorsen-Meyer, H., Igel, Christian & Sillesen, Martin Hylleholt, 23 Sep 2021, In: Scientific Reports. 11, 1, 10 p., 18959.

Research output: Contribution to journal › Journal article › Research › peer-review

Cardiac arrhythmias in critically ill patients with coronavirus disease 2019: A retrospective population-based cohort study

Wetterslev, M., Jacobsen, P. K., Hassager, Christian, Jøns, C., Risum, N., Pehrson, S., Bastiansen, A., Andreasen, Anne Sofie, Tjelle Kristiansen, K., Bestle, Morten Heiberg, Mohr, T., Møller-Sørensen, H. & Perner, Anders, Jul 2021, In: Acta Anaesthesiologica Scandinavica. 65, 6, p. 770-777 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Treating critically ill anemic patients with erythropoietin: less is more

The ESICM Transfusion Guideline Part 1 Task force, T. E. T. G. P. 1. T. F., Feb 2021, In: Intensive Care Medicine. 47, 2, p. 256-257 2 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

A Multicenter Observational Study Evaluating Outcomes Associated With Antibiotic Combination Versus Monotherapy in Patients With Septic Shock

Torisson, G., Bruun Madsen, M., Schmidt Davidsen, A., Perner, Anders, Lipman, J., Dulhunty, J. & Sjövall, F., 2021, In: Critical Care Explorations. 3, 5, 10 p., e0383.

Research output: Contribution to journal › Journal article › Research › peer-review

A new tool to assess Clinical Diversity In Meta-analyses (CDIM) of interventions

Barbateskovic, M., Koster, T. M., Eck, R. J., Maagaard, M., Afshari, A., Blokzijl, F., Cronhjort, M., Dieperink, W., Fabritius, M. L., Feinberg, J., French, C., Gareb, B., Geisler, A., Granholm, A., Hiemstra, B., Hu, R., Imberger, G., Jensen, B. T., Jonsson, A. B., Karam, O. & 25 others, Kong, D. Z., Korang, S. K., Koster, G., Lai, B., Liang, N., Lundstrøm, Lars Hyldborg, Marker, S., Meyhoff, T. S., Nielsen, E. E., Nørskov, A. K., Munch, M. W., Risom, E. C., Rygård, S. L., Safi, S., Sethi, N., Sjövall, F., Lauridsen, S. V., van Bakelen, N., Volbeda, M., van der Horst, I. C. C., Gluud, C., Perner, Anders, Møller, Morten Hylander, Keus, E. & Wetterslev, J., 2021, In: Journal of Clinical Epidemiology. 135, p. 29-41

Research output: Contribution to journal › Journal article › Research › peer-review

Acetate‐ vs lactate‐buffered crystalloid solutions: Protocol for a systematic review with meta‐analysis and trial sequential analysis

Ellekjaer, K. L., Perner, Anders, Sivapalan, P. & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 1, p. 123-127 5 p.

Research output: Contribution to journal › Review › Research › peer-review

COVID-19 versus influenza A/B supeRInfectionS in the IntenSive care unit (CRISIS): Protocol for a Danish nationwide cohort study

Mikkelsen, V. S., Helleberg, M., Haase, N., Møller, Morten Hylander, Granholm, A., Storgaard, M., Jonsson, A. B., Schønning, Kristian, Reiter, N., Sigurðsson, S. Þ., Voldstedlund, M., Christensen, S. & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 9, p. 1345-1350 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Characteristics, interventions, and longer term outcomes of COVID‐19 ICU patients in Denmark—A nationwide, observational study

Haase, N., Plovsing, R., Christensen, S., Poulsen, L. M., Brøchner, A. C., Rasmussen, B. S., Helleberg, M., Jensen, J. U. S., Andersen, L. P. K., Siegel, H., Ibsen, M., Jørgensen, V., Winding, R., Iversen, S., Pedersen, H. P., Madsen, J., Sølling, C., Garcia, R. S., Michelsen, J., Mohr, T. & 10 others, Mannering, A., Espelund, U. S., Bundgaard, H., Kirkegaard, L., Smitt, M., Buck, D. L., Ribergaard, N., Pedersen, H. S., Christensen, B. V. & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 1, p. 68-75 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Clinical validation of precision medicine protocols: the last mile is the longest

Casaer, M. P., De Jong, A. & Perner, Anders, 2021, In: Intensive Care Medicine. 47, p. 80-82 3 p.

Research output: Contribution to journal › Editorial › Research › peer-review

Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients

Jimenez-Solem, E., Petersen, T. S., Hansen, C., Hansen, C., Lioma, C., Igel, C., Boomsma, W., Krause, O., Lorenzen, S., Selvan, R., Petersen, J., Nyeland, M. E., Ankarfeldt, M. Z., Virenfeldt, G. M., Winther-Jensen, M., Linneberg, A., Ghazi, M. M., Detlefsen, N., Lauritzen, A. D., Smith, A. G. & 15 others, de Bruijne, Marleen, Ibragimov, Bulat, Petersen, Jens, Lillholm, Martin, Middleton, Jon Anthony, Mogensen, S. H., Thorsen-Meyer, H., Perner, Anders, Helleberg, M., Kaas-Hansen, Benjamin Skov, Bonde, M., Bonde, A., Pai, A., Nielsen, Mads & Sillesen, Martin Hylleholt, 2021, In: Scientific Reports. 11, 1, 12 p., 3246.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia The COVID STEROID 2 Randomized Trial

Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Saseedharan, S., Benfield, T., Wahlin, R. R., Rasmussen, B. S., Andreasen, A. S., Poulsen, L. M., Cioccari, L., Khan, M. S., Kapadia, F., Divatia, J. V., Brochner, A. C., Bestle, M. H., Helleberg, M., Michelsen, J., Padmanaban, A., Bose, N., Møller, A. & 59 others, Borawake, K., Kristiansen, K. T., Shukla, U., Chew, M. S., Dixit, S., Ulrik, Charlotte Suppli, Amin, P. R., Chawla, R., Wamberg, C. A., Shah, M. S., Darfelt, I. S., Jorgensen, V. L., Smitt, M., Granholm, A., Kjær, M. N., Møller, Morten Hylander, Meyhoff, T. S., Vesterlund, G. K., Hammond, N. E., Micallef, S., Bassi, A., John, O., Jha, A., Cronhjort, M., Jakob, S. M., Gluud, C., Lange, Theis, Kadam, V., Marcussen, Klaus Vennick, Hollenberg, J., Hedman, A., Nielsen, H., Schjorring, O. L., Jensen, M. Q., Leistner, J. W., Jonassen, T. B., Kristensen, C. M., Clapp, E. C., Hjortso, C. J. S., Jensen, T. S., Halstad, L. S., Bak, E. R. B., Zaabalawi, R., Metcalf-Clausen, M., Abdi, S., Hatley, E. V., Aksnes, T. S., Gleipner-Andersen, E., Alarcon, A. F., Yamin, G., Heymowski, A., Berggren, A., La Cour, K., Weihe, S., Pind, A. H., Engstrom, J., Jha, V., Venkatesh, B. & Perner, Anders, 2021, In: J A M A: The Journal of the American Medical Association. 326, 18, p. 1807-1817 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of immunoglobulin G on cytokine response in necrotising soft-tissue infection: A post hoc analysis

Hedetoft, M., Madsen, M. B., Perner, Anders, Garred, Peter & Hyldegaard, Ole, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 9, p. 1293-1299 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021

Evans, L., Rhodes, A., Alhazzani, W., Antonelli, M., Coopersmith, C. M., French, C., Machado, F. R., Mcintyre, L., Ostermann, M., Prescott, H. C., Schorr, C., Simpson, S., Joost Wiersinga, W., Alshamsi, F., Angus, D. C., Arabi, Y., Azevedo, L., Beale, R., Beilman, G., Belley-Cote, E. & 40 others, Burry, L., Cecconi, M., Centofanti, J., Yataco, A. C., De Waele, J., Dellinger, R. P., Doi, K., Du, B., Estenssoro, E., Ferrer, R., Gomersall, C., Hodgson, C., Møller, Morten Hylander, Iwashyna, T., Jacob, S., Kleinpell, R., Klompas, M., Koh, Y., Kumar, A., Kwizera, A., Lobo, S., Masur, H., McGloughlin, S., Mehta, S., Mehta, Y., Mer, M., Nunnally, M., Oczkowski, S., Osborn, T., Papathanassoglou, E., Perner, Anders, Puskarich, M., Roberts, J., Schweickert, W., Seckel, M., Sevransky, J., Sprung, C. L., Welte, T., Zimmerman, J. & Levy, M., 2021, In: Critical Care Medicine. 49, 11, p. 1974-1982 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Handling oxygenation targets in ICU patients with COVID-19—Protocol and statistical analysis plan in the HOT-COVID trial

Mølgaard Nielsen, F., Lass Klitgaard, T., Crescioli, E., Rosborg Aagaard, S., Andreasen, Anne Sofie, Musaeus Poulsen, L., Siegemund, M., Craveiro Brøchner, A., Bestle, Morten Heiberg, Andi Iversen, S., Brand, B. A., Laake, J. H., Grøfte, T., Hildebrandt, T., Lange, Theis, Perner, Anders, Lilleholt Schjørring, O. & Steen Rasmussen, B., 2021, In: Acta Anaesthesiologica Scandinavica. 65, 10, p. 1497-1504 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Higher vs Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia (COVID STEROID 2) trial: Protocol for a secondary Bayesian analysis

Granholm, A., Munch, M. W., Myatra, S. N., Vijayaraghavan, B. K. T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Kjær, M. B. N., Vesterlund, G. K., Meyhoff, T. S., Helleberg, M., Møller, M. H., Benfield, T., Venkatesh, B., Hammond, N., Micallef, S., Bassi, A., John, O., Jha, V. & 25 others, Kristiansen, K. T., Ulrik, Charlotte Suppli, Jørgensen, V. L., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Poulsen, L. M., Rasmussen, B. S., Brøchner, A. C., Strøm, T., Møller, A., Khan, M. S., Padmanaban, A., Divatia, J. V., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Gluud, C., Lange, Theis & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 5, p. 702-710 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Higher vs Lower Oxygenation Strategies in Acutely Ill Adults: A Systematic Review With Meta-Analysis and Trial Sequential Analysis

Barbateskovic, M., Schjørring, O. L., Krauss, S. R., Meyhoff, Christian Sylvest, Jakobsen, J. C., Rasmussen, B. S., Perner, Anders & Wetterslev, J., 2021, In: Chest. 159, 1, p. 154-173 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Higher vs lower doses of dexamethasone in patients with COVID-19 and severe hypoxia (COVID STEROID 2) trial: Protocol and statistical analysis plan

Warrer Munch, M., Granholm, A., Nainan Myatra, S., Kumar Tirupakuzhi Vijayaraghavan, B., Cronhjort, M., Rubenson Wahlin, R., Jakob, S. M., Cioccari, L., Nørregaard Kjær, M. B., Kingo Vesterlund, G., Sylvest Meyhoff, T., Helleberg, M., Hylander Møller, M., Benfield, T., Venkatesh, B., Hammond, N., Micallef, S., Bassi, A., John, O., Jha, V. & 25 others, Tjelle Kristiansen, K., Ulrik, Charlotte Suppli, Lind Jørgensen, V., Smitt, M., Bestle, Morten Heiberg, Andreasen, Anne Sofie, Musaeus Poulsen, L., Steen Rasmussen, B., Craveiro Brøchner, A., Strøm, T., Møller, A., Saif Khan, M., Padmanaban, A., Vasishtha Divatia, J., Saseedharan, S., Borawake, K., Kapadia, F., Dixit, S., Chawla, R., Shukla, U., Amin, P., Chew, M. S., Gluud, C., Lange, Theis & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 6, p. 834-845 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy

Klitgaard, T. L., Schjørring, O. L., Nielsen, F. M., Meyhoff, Christian Sylvest, Barbateskovic, M., Wetterslev, J., Perner, Anders & Rasmussen, B. S., 2021, In: Journal of Intensive Care. 9, 1, 5 p., 72.

Research output: Contribution to journal › Letter › Research › peer-review

Low-dose hydrocortisone in patients with COVID-19 and severe hypoxia: The COVID STEROID randomised, placebo-controlled trial

Munch, M. W., Meyhoff, T. S., Helleberg, M., Kjær, M. B. N., Granholm, A., Hjortsø, C. J. S., Jensen, T. S., Møller, M. H., Hjortrup, P. B., Wetterslev, M., Vesterlund, G. K., Russell, L., Jørgensen, V. L., Kristiansen, K. T., Benfield, T., Ulrik, C. S., Andreasen, A. S., Bestle, M. H., Poulsen, L. M., Hildebrandt, T. & 52 others, Knudsen, Lene Surland, Møller, A., Sølling, C. G., Brøchner, A. C., Rasmussen, B. S., Nielsen, H., Christensen, S., Strøm, T., Cronhjort, M., Wahlin, R. R., Jakob, S. M., Cioccari, L., Venkatesh, B., Hammond, N., Jha, V., Myatra, S. N., Jensen, M. Q., Leistner, J. W., Mikkelsen, V. S., Svenningsen, J. S., Laursen, S. B., Hatley, E. V., Kristensen, C. M., Al-Alak, A., Clapp, E., Jonassen, T. B., Bjerregaard, C. L., Østerby, N. C. H., Jespersen, M. M., Abou-Kassem, D., Lassen, M. L., Zaabalawi, R., Daoud, M. M., Abdi, S., Meier, N., la Cour, K., Derby, C. B., Damlund, B. R., Laigaard, J., Andersen, L. L., Mikkelsen, J., Jensen, J. L. S., Rasmussen, A. H., Arnerlöv, E., Lykke, M., Holst-Hansen, M. Z. B., Tøstesen, B. W., Schwab, J., Madsen, E. K., Gluud, C., Lange, Theis & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 10, p. 1421-1430 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure

Schjorring, O. L., Klitgaard, T. L., Perner, A., Wetterslev, J., Lange, T., Siegemund, M., Backlund, M., Keus, F., Laake, J. H., Morgan, M., Thormar, K. M., Rosborg, S. A., Bisgaard, J., Erntgaard, A. E. S., Lynnerup, A-S. H., Pedersen, R. L., Crescioli, E., Gielstrup, T. C., Behzadi, M. T., Poulsen, L. M. & 31 others, Estrup, S., Laigaard, J. P., Andersen, C., Mortensen, C. B., Brand, B. A., White, J., Jarnvig, I., Møller, Morten Hylander, Quist, L., Bestle, Morten Heiberg, Schonemann-Lund, M., Kamper, M. K., Hindborg, M., Hollinger, A., Gebhard, C. E., Zellweger, N., Meyhoff, Christian Sylvest, Hjort, M., Bech, L. K., Grofte, T., Bundgaard, H., Ostergaard, L. H. M., Thyo, M. A., Hildebrandt, T., Uslu, B., Solling, C. G., Pedersen, U. G., Andreasen, Anne Sofie, Kjaer, M. N., Rasmussen, B. S. & HOT-ICU Investigators, H. I., 2021, In: New England Journal of Medicine. 384, 14, p. 1301-1311 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Management of acute atrial fibrillation in the intensive care unit: An international survey

Wetterslev, M., Møller, M. H., Granholm, A., Hassager, C., Haase, N., Aslam, T. N., Shen, J., Young, P. J., Aneman, A., Hästbacka, J., Siegemund, M., Cronhjort, M., Lindqvist, E., Myatra, S. N., Kalvit, K., Arabi, Y. M., Szczeklik, W., Sigurdsson, M. I., Balik, M., Keus, F. & 31 others, Perner, Anders, Huang, B., Yan, M., Liu, W., Deng, Y., Zhang, L., Suk, P., Mørk Sørensen, K., Andreasen, Anne Sofie, Bestle, Morten Heiberg, Krag, M., Poulsen, L. M., Hildebrandt, T., Møller, Kirsten, Møller-Sørensen, H., Bove, J., Kilsgaard, T. A., Salam, I. A., Brøchner, A. C., Strøm, T., Sølling, C., Kolstrup, L., Boczan, M., Rasmussen, B. S., Darfelt, I. S., Jalkanen, V., Lehto, P., Reinikainen, M., Kárason, S., Sigvaldason, K. & the AFIB-ICU collaborators, T. A. C., 2021, In: Acta Anaesthesiologica Scandinavica. 66, 3, p. 375-385

Research output: Contribution to journal › Journal article › Research › peer-review

New-onset atrial fibrillation in the intensive care unit: Protocol for an international inception cohort study (AFIB-ICU)

Wetterslev, M., Møller, Morten Hylander, Granholm, A., Haase, N., Hassager, Christian, Lange, Theis, Hastbacka, J., Wilkman, E., Myatra, S. N., Shen, J., An, Y., Siegemund, M., Young, P. J., Aslam, T. N., Szczeklik, W., Aneman, A., Arabi, Y. M., Cronhjort, M., Keus, F. & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 6, p. 846-851 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Patient and public involvement in contemporary large intensive care trials: Protocol for a meta-epidemiological study

Barot, E., Kjær, M. B. N., Collet, M., Crescioli, E., Rasmussen, B. S., Estrup, S., Mortensen, C. B., Vesterlund, G. K., Sivapalan, P., Anthon, C. T., Bruun, C. R. L., Poulsen, L. M., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2021, In: Acta Anaesthesiologica Scandinavica. 65, 9, p. 1351-1354 4 p.

Research output: Contribution to journal › Review › Research › peer-review

Patient-important outcomes other than mortality in recent ICU trials: protocol for a scoping review

Granholm, A., Kaas-Hansen, Benjamin Skov, Kjaer, M. N., Anthon, C. T., Sivapalan, P., Schjørring, O. L., Andersen, L. W., Mathiesen, Ole, Strøm, T., Jensen, Aksel Karl Georg, Perner, Anders & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 7, p. 1002-1007 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Predictors of gastrointestinal bleeding in adult ICU patients in the SUP-ICU trial

Granholm, A., Krag, M., Marker, S., Alhazzani, W., Perner, Anders & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 6, p. 792-800 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Preferences for the measurement and supplementation of magnesium, phosphate and zinc in ICUs: The international WhyTrace survey

Vesterlund, G. K., Ostermann, M., Myatra, S. N., Arabi, Y. M., Sadat, M., Zampieri, F. G., Cronhjort, M., Schefold, J. C., Stöhr, F., Buanes, E. A., Bäcklund, M., Thormar, K. M. & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 3, p. 390-396

Research output: Contribution to journal › Journal article › Research › peer-review

Prophylactic acid suppressants in children in the intensive care unit: a systematic review with meta-analysis and trial sequential analysis

Jensen, M. M., Marker, S., Do, H. Q., Barbateskovic, M., Perner, Anders & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 3, p. 292-301 10 p.

Research output: Contribution to journal › Review › Research › peer-review

Prophylactic platelet transfusions in hospitalised patients with thrombocytopenia—Protocol for a systematic review with meta-analysis

Anthon, C. T., Sivapalan, P., Granholm, A., Pène, F., Puxty, K., Perner, Anders, Møller, Morten Hylander & Russell, Lene, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 7, p. 988-994 7 p.

Research output: Contribution to journal › Review › Research › peer-review

Risk factors for long-term cognitive impairment in ICU survivors: A multicenter, prospective cohort study

Collet, M. O., Egerod, Ingrid Eugenie, Thomsen, Thordis, Wetterslev, J., Lange, Theis, Ebdrup, Bjørn & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 1, p. 92-99

Research output: Contribution to journal › Journal article › Research › peer-review

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

Evans, L., Rhodes, A., Alhazzani, W., Antonelli, M., Coopersmith, C. M., French, C., Machado, F. R., Mcintyre, L., Ostermann, M., Prescott, H. C., Schorr, C., Simpson, S., Wiersinga, W. J., Alshamsi, F., Angus, D. C., Arabi, Y., Azevedo, L., Beale, R., Beilman, G., Belley-Cote, E. & 40 others, Burry, L., Cecconi, M., Centofanti, J., Coz Yataco, A., De Waele, J., Dellinger, R. P., Doi, K., Du, B., Estenssoro, E., Ferrer, R., Gomersall, C., Hodgson, C., Møller, Morten Hylander, Iwashyna, T., Jacob, S., Kleinpell, R., Klompas, M., Koh, Y., Kumar, A., Kwizera, A., Lobo, S., Masur, H., McGloughlin, S., Mehta, S., Mehta, Y., Mer, M., Nunnally, M., Oczkowski, S., Osborn, T., Papathanassoglou, E., Perner, Anders, Puskarich, M., Roberts, J., Schweickert, W., Seckel, M., Sevransky, J., Sprung, C. L., Welte, T., Zimmerman, J. & Levy, M., 2021, In: Intensive Care Medicine. 47, 11, p. 1181-1247

Research output: Contribution to journal › Journal article › Research › peer-review

The effects of adding quinolones to beta-lactam antibiotics for sepsis

Korang, S. K., Maagaard, M., Feinberg, J. B., Perner, Anders, Gluud, C. & Jakobsen, J. C., 2021, In: Acta Anaesthesiologica Scandinavica. 65, 8, p. 1023-1032

Research output: Contribution to journal › Review › Research › peer-review

Thrombocytopenia in intensive care unit patients: A scoping review

Jonsson, A. B., Rygård, S. L., Hildebrandt, T., Perner, Anders, Møller, Morten Hylander & Russell, L., 2021, In: Acta Anaesthesiologica Scandinavica. 65, 1, p. 2-14 13 p.

Research output: Contribution to journal › Review › Research › peer-review

Use of crystalloids and colloids in Europe per year from 2010 to 2019: Protocol for an international descriptive study

Zellweger, N. M., Møller, Morten Hylander, Ellekjær, K. L., Jonsson, A. B., Svan, K. B., Siegemund, M. & Perner, Anders, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 10, p. 1514-1517

Research output: Contribution to journal › Journal article › Research › peer-review

Use of hydroxyethyl starch in sepsis research: A systematic review with meta-analysis

Johansen, J. R., Perner, Anders, Brodtkorb, J. H. & Møller, Morten Hylander, 2021, In: Acta Anaesthesiologica Scandinavica. 65, 10, p. 1355-1364

Research output: Contribution to journal › Journal article › Research › peer-review

Respiratory Mechanics and Outcomes in Immunocompromised Patients With ARDS

Demoule, A., Antonelli, M., Schellongowski, P., Pickkers, P., Soares, M., Meyhoff, T. S., Rello, J., Bauer, P., Van De Louw, A., Lemiale, V., Grimaldi, D., Martin-loeches, I., Balik, M., Mehta, S., Kouatchet, A., Barratt-due, A., Valkonen, M., Reignier, J., Metaxa, V., Moreau, A. S. & 89 others, Burghi, G., Mokart, D., Mayaux, J., Darmon, M., Azoulay, E., Amrein, K., Schellongowski, P., Staundinger, T., Heinz, G., Sengölge, G., Zauner, C., Jaksch, P., Taccone, F. S., Grimaldi, D., Meert, A. P., Benoît, D., Silva, U. V. A., Pierre De Moraes, A. P., Lishoa, T., Soares, M., Salluh, J., Viana, W., Moralez, G., Correa, T. D., Mehta, S., Shah, U., Karvunidis, T., Martin, B., Russinova, K., Perner, Anders, Meyhoff, T. S., Jonas, N., Bukan, R. B., Møller, Ann, Nielsen, L. B., Kouatchet, A., Seguin, A., Chermak, A., Terzi, N., Vinatier, I., Moreau, A. S., Wallet, F., Mokart, D., Klouche, K., Platon, L., Gaborit, B., Barbier, F., Pène, F., Rabbat, A., Demoule, A., Mayaux, J., Azoulay, E., Lemiale, V., N'yunga, M., Girault, C., Lemaitre, C., Artaud-macari, E., Darmon, M., Bruneel, F., Moreau, A. S., Valkonen, M., Kuitunen, A., Marsh, B., Misericordia, M., Martin-loeches, I., Mahon, A. M., Cinnella, G., Cotoia, A., Riuniti, O., Antonelli, M., Montini, L., Spoelstra De Man, A., Landburg, P. P., Bergmans, D., Pickkers, P., Hemelaar, P., Kaufmann, T., Barrat-due, A., Klepstad, P., Rello, J., Encina, B., Moreno, G., Crespi, L. S., Rodriguez-ruiz, E., Metaxa, V., Burghi, G., Van De Louw, A., Bauer, P. & Hemang, Y., 1 Nov 2020, In: Chest. 158, 5, p. 1947-1957 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Prophylactic use of acid suppressants in adult acutely ill hospitalised patients: A systematic review with meta-analysis and trial sequential analysis

Marker, S., Barbateskovic, M., Perner, Anders, Wetterslev, J., Jakobsen, J. C., Krag, M., Granholm, A., Anthon, C. T. & Møller, Morten Hylander, Jul 2020, In: Acta Anaesthesiologica Scandinavica. 64, 6, p. 714-728 15 p.

Research output: Contribution to journal › Review › Research › peer-review