Autism spectrum disorder in individuals with anorexia nervosa and in their first- and second-degree relatives: Danish nationwide register-based cohort-study
Research output: Contribution to journal › Journal article › Research › peer-review
BACKGROUND: Clinical and population-based studies report increased prevalence of autism spectrum disorders (ASD) in individuals with anorexia nervosa and in their relatives. No nationwide study has yet been published on co-occurrence of these disorders.
AIMS: To investigate comorbidity of ASD in individuals with anorexia nervosa, and aggregation of ASD and anorexia nervosa in their relatives.
METHOD: In Danish registers we identified all individuals born in 1981-2008, their parents, and full and half siblings, and linked them to data on hospital admissions for psychiatric disorders.
RESULTS: Risk of comorbidity of ASD in probands with anorexia nervosa and aggregation of ASD in families of anorexia nervosa probands were increased. However, the risk of comorbid and familial ASD did not differ significantly from comorbid and familial major depression or any psychiatric disorder in anorexia nervosa probands.
CONCLUSIONS: We confirm aggregation of ASD in probands with anorexia nervosa and in their relatives; however, the relationship between anorexia nervosa and ASD appears to be non-specific.
| Original language | English |
|---|---|
| Journal | British Journal of Psychiatry |
| Volume | 206 |
| Issue number | 5 |
| Pages (from-to) | 401-7 |
| Number of pages | 7 |
| ISSN | 0007-1250 |
| DOIs | |
| Publication status | Published - May 2015 |
- Adolescent, Anorexia Nervosa, Autism Spectrum Disorder, Cohort Studies, Comorbidity, Denmark, Depressive Disorder, Major, Family, Female, Humans, Male, Regression Analysis, Risk Factors, Sex Distribution, Siblings
Research areas
ID: 162374426