Marianne Benn
Clinical Professor
- 2024
- Published
Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive Reliability (FOREVER)—A cohort study in a Danish high street optician setting: Design and methodology
Freiberg, J., Rovelt, J., Gazzard, G., Cour, M. L., Kolko, M., Torp‐Pedersen, C., Benn, M., Brunak, S., Cour, M. L., Tolstrup, J., Toft‐Petersen, A. P., Burgdorf, K. S., Banasik, K., Chmura, P. J., Freiberg, J., Rovelt, J., Thornit, D. N., Foster, P., Gazzard, G., Crabb, D. P. & 4 others, , 2024, In: Acta Ophthalmologica. 102, 1, p. 80-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglycaemia, diabetes and risk of fragility fractures: observational and Mendelian randomisation studies
Emanuelsson, F., Afzal, Shoaib, Jørgensen, Niklas Rye, Nordestgaard, Børge & Benn, Marianne, 2024, In: Diabetologia. 67, 2, p. 301-311 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma adiponectin levels and risk of heart failure, atrial fibrillation, aortic valve stenosis, and myocardial infarction: large-scale observational and Mendelian randomization evidence
Nielsen, M. B., Çolak, Y., Benn, Marianne, Mason, A., Burgess, S. & Nordestgaard, Børge, 2024, In: Cardiovascular Research. 120, 1, p. 95-107 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
SGLT2-inhibition increases total, LDL, and HDL cholesterol and lowers triglycerides: Meta-analyses of 60 randomized trials, overall and by dose, ethnicity, and drug type
Bechmann, L. E., Emanuelsson, F., Nordestgaard, Børge & Benn, Marianne, 2024, (Accepted/In press) In: Atherosclerosis. 117236.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Health behavioral responses to parental myocardial infarction and impact on own risk of disease in the general population
Skouenborg, C., Jørgensen, M. L., Nielsen, Torben Heien & Benn, Marianne, 6 Jul 2023, In: Frontiers in Public Health. 11, 9 p., 1200593.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in solute carrier family 5 member 2 mimicking sodium-glucose co-transporter 2-inhibition and risk of cardiovascular disease and all-cause mortality: reduced risk not explained by lower plasma glucose
Bechmann, L. E., Emanuelsson, F., Nordestgaard, Børge & Benn, Marianne, 2023, In: Cardiovascular Research. 119, 14, p. 2482-2493 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Height Explains Sex Difference in Atrial Fibrillation Risk: Copenhagen General Population Study
Marott, J. L., Jensen, M. T., Benn, Marianne, Knegt, M. C. D., O'Keefe, J. H., Lavie, C. J., Schnohr, P., Nordestgaard, Børge & Jensen, G. B., 2023, In: Mayo Clinic Proceedings. 98, 6, p. 846-855 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Red blood cell parameters in early childhood: a prospective cohort study
Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Hansen, M. K., Sillesen, A. S., Vøgg, O. R. B., Raja, A. A., Rasmussen, I. J., Kamstrup, P. R., Benn, Marianne, Iversen, Kasper, Bundgård, Henning & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry and Laboratory Medicine. 61, 2, p. 275-284 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society
Roeters Van Lennep, J. E., Tokgözoǧlu, L. S., Badimon, L., Dumanski, S. M., Gulati, M., Hess, C. N., Holven, K. B., Kavousi, M., Kaylkçloǧlu, M., Lutgens, E., Michos, E. D., Prescott, Eva, Stock, J. K., Tybjærg-Hansen, Anne, Wermer, M. J. H. & Benn, Marianne, 2023, In: European Heart Journal. 44, 39, p. 4157-4173 17 p.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
Causal risk factors for asthma in Mendelian randomization studies: A systematic review and meta-analysis
Mikkelsen, H., Landt, E. M., Benn, Marianne, Nordestgaard, Børge & Dahl, Morten, 2022, In: Clinical and Translational Allergy. 12, 11, e12207.Research output: Contribution to journal › Review › Research › peer-review
- Published
Familial Hypercholesterolemia Prevalence Among Ethnicities—Systematic Review and Meta-Analysis
Toft-Nielsen, F., Emanuelsson, F. & Benn, Marianne, 2022, In: Frontiers in Genetics. 13, 840797.Research output: Contribution to journal › Review › Research › peer-review
- Published
Obesity increases heart failure incidence and mortality: observational and Mendelian randomization studies totalling over 1 million individuals
Benn, Marianne, Marott, S. C. W., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: Cardiovascular Research. 118, 18, p. 3576-3585 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma adiponectin and risk of asthma: observational analysis, genetic Mendelian randomisation and meta-analysis
Nielsen, M. B., Nordestgaard, Børge, Benn, Marianne & colak, Y., 2022, In: Thorax. 77, 11, p. 1070–1077 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The spoils of war and the long-term spoiling of health conditions of entire nations
Navarese, E. P., Grzelakowska, K., Mangini, F., Kubica, J., Banach, M., Benn, Marianne, Binder, C. J., Borén, J., Catapano, A., Kronenberg, F., Mallat, Z., Moulin, P., Öörni, K., Ray, K. K., Roeters van Lennep, J. E., Romeo, S., Tokgozoglu, L., von Eckardstein, A., Zambon, A. & Raggi, P., 2022, In: Atherosclerosis. 352, p. 76-79Research output: Contribution to journal › Editorial › Research › peer-review
- 2021
- Published
Atrial Fibrillation and Chronic Kidney Disease
Benn, Marianne, 2021, In: European Heart Journal. 42, 29, p. 2824-2826 3 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Vallejo-Vaz, A. J., Stevens, C. A. T., Lyons, A. R. M., Dharmayat, K. I., Freiberger, T., Hovingh, G. K., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar-Salinas, C. A., Alhabib, K. F., Alkhnifsawi, M., Almahmeed, W., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A. & 31 others, , 2021, In: The Lancet. 398, 10312, p. 1713-1725 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis
Benn, Marianne, Emanuelsson, F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Diabetologia. 64, p. 1492–1503Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LDL-Cholesterol versus Glucose in Microvascular and Macrovascular Disease
Emanuelsson, F. & Benn, Marianne, 2021, In: Clinical Chemistry. 67, 1, p. 167-182 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low Plasma Adiponectin in Risk of Type 2 Diabetes: Observational Analysis and One- and Two-Sample Mendelian Randomization Analyses in 756,219 Individuals
Nielsen, M. B., Çolak, Y., Benn, Marianne & Nordestgaard, Børge, 2021, In: Diabetes. 70, 11, p. 2694-2705 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Peripheral Neuropathy-Time for Better Biomarkers?
Benn, Marianne, 1 May 2020, In: Clinical Chemistry. 66, 5, p. 638-640 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Glucose Level on Micro- and Macrovascular Disease in the General Population: A Mendelian Randomization Study
Emanuelsson, F., Marott, S., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Benn, Marianne, Apr 2020, In: Diabetes Care. 43, 4, p. 894-902 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Causal Relationship between Plasma Adiponectin and Body Mass Index: One- and Two-Sample Bidirectional Mendelian Randomization Analyses in 460 397 Individuals
Nielsen, M. B., Çolak, Y., Benn, Marianne & Nordestgaard, Børge, 2020, In: Clinical Chemistry. 66, 12, p. 1548-1557Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Repositioning of the global epicentre of non-optimal cholesterol
NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Taddei, C., Zhou, B., Bixby, H., Nordestgaard, Børge, Benn, Marianne, Linneberg, Allan René, Tybjærg-Hansen, Anne, Cisneros, J. Z., Gregg, E. W., Ezzati, M. & Sørensen, Thorkild I.A., 2020, In: Nature. 582, 7810, p. 73-77Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type-2 diabetes and risk of dementia: observational and Mendelian randomisation studies in 1 million individuals
Thomassen, J. Q., Tolstrup, J. S., Benn, Marianne & Frikke-Schmidt, Ruth, 2020, In: Epidemiology and Psychiatric Sciences. 29, 11 p., e118.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Impact of LDL Cholesterol on Microvascular Versus Macrovascular Disease: A Mendelian Randomization Study
Emanuelsson, F., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Sep 2019, In: Journal of the American College of Cardiology. 74, 11, p. 1465-1476Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality
Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3102-3114Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Causal Associations in Type 2 Diabetes Development
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 4, p. 1313-1324Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study
Carter, A. R., Borges, M., Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, G., Nordestgaard, Børge & Lawlor, D. A., 2019, In: JAMA Network Open. 2, 3, 14 p., e190305.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to Letter to the Editor: "Familial Hypercholesterolemia and Risk of Peripheral Arterial Disease and Chronic Kidney Disease"
Emanuelsson, F., Nordestgaard, Børge & Benn, Marianne, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 8, p. 3125-3126Research output: Contribution to journal › Comment/debate › Research
- Published
Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis
Yang, Y., van der Klaauw, A. A., Zhu, L., Cacciottolo, T. M., He, Y., Stadler, L. K. J., Wang, C., Xu, P., Saito, K., Hinton, A., Yan, X., Keogh, J. M., Henning, E., Banton, M. C., Hendricks, A. E., Bochukova, E. G., Mistry, V., Lawler, K. L., Liao, L., Xu, J. & 306 others, , 2019, In: Nature Communications. 10, 14 p., 1718.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Relationship of Familial Hypercholesterolemia and High Low-Density Lipoprotein Cholesterol to Ischemic Stroke: Copenhagen General Population Study
Beheshti, S., Madsen, C. M., Varbo, A., Benn, Marianne & Nordestgaard, Børge, Aug 2018, In: Circulation. 138, 6, p. 578-589 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From genome-wide association studies to Mendelian randomization: novel opportunities for understanding cardiovascular disease causality, pathogenesis, prevention, and treatment
Benn, Marianne & Nordestgaard, Børge, 15 Jul 2018, In: Cardiovascular Research. 114, 9, p. 1192-1208 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, , 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis
European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium, E. P. I. I. C. A. N. D. (. C., 2018, In: JAMA Cardiology. 3, 7, p. 619-627 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial Hypercholesterolemia and Risk of Peripheral Arterial Disease and Chronic Kidney Disease
Emanuelsson, F., Nordestgaard, Børge & Benn, Marianne, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4491-4500Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Vallejo-Vaz, A. J., Marco, M. D., Stevens, C. A. T., Akram, A., Freiberger, T., Hovingh, G. K., Kastelein, J. J. P., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar Salinas, C. A., Al-Khnifsawi, M., Alkindi, F. A., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A. & 248 others, , 2018, In: Atherosclerosis. 277, p. 234-255 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, , Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits
Tachmazidou, I., Süveges, D., Min, J. L., Ritchie, G. R. S., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., McCarthy, S., Crawford, A. J., Bombieri, C., Cocca, M., Farmaki, A-E., Gaunt, T. R., Jousilahti, P., Kooijman, M. N., Lehne, B., Malerba, G. & 31 others, , 1 Jun 2017, In: American Journal of Human Genetics. 100, 6, p. 865-884 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study
Benn, Marianne, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 24 Apr 2017, In: B M J. 357, 11 p., j1648.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Filaggrin loss-of-function mutations as risk factors for ischemic stroke in the general population
Varbo, A., Nordestgaard, Børge & Benn, Marianne, Apr 2017, In: Journal of Thrombosis and Haemostasis. 15, 4, p. 624-635 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare and low-frequency coding variants alter human adult height
Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, , 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic testing for familial hypercholesterolaemia is essential in individuals with high LDL cholesterol: Who does it in the world?
Nordestgaard, Børge & Benn, Marianne, 2017, In: European Heart Journal. 38, 20, p. 1580-1583Research output: Contribution to journal › Editorial › Research
- 2016
- Published
High body mass index and cancer risk
Benn, Marianne, Tybjærg-Hansen, Anne, Smith, G. D. & Nordestgaard, Børge, Sep 2016, In: European Journal of Epidemiology. 31, 9, p. 879-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein(a) and familial hypercholesterolaemia - Authors' reply
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Sep 2016, In: The Lancet Diabetes and Endocrinology. 4, 9, p. 730-731 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis
Langsted, A., Nordestgaard, Børge, Benn, Marianne, Tybjærg-Hansen, Anne & Kamstrup, P. R., Sep 2016, In: The Journal of clinical endocrinology and metabolism. 101, 9, p. 3281-3287 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Components of the Metabolic Syndrome and Risk of Type 2 Diabetes
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Aug 2016, In: The Journal of clinical endocrinology and metabolism. 101, 8, p. 3212-3221 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High lipoprotein(a) as a possible cause of clinical familial hypercholesterolaemia: a prospective cohort study
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jul 2016, In: The Lancet Diabetes and Endocrinology. 4, 7, p. 577-587 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plakophilin-2 c.419C>T and risk of heart failure and arrhythmias in the general population
Christensen, A. H., Kamstrup, P. R., Gandjbakhch, E., Benn, Marianne, Jensen, J. S., Bundgård, Henning, Villard, E. & Tybjærg-Hansen, Anne, May 2016, In: European Journal of Human Genetics. 24, 5, p. 732-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to the Letter: Response to "Use of biomarkers to identify new drug targets and to predict risk of cardiometabolic outcomes" by Abasi A., et al
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Feb 2016, In: The Journal of clinical endocrinology and metabolism. 101, 2, p. L22-L23Research output: Contribution to journal › Letter › Research › peer-review
- Published
Sex Hormones and Ischemic Stroke: A Prospective Cohort Study and Meta-Analyses
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Jan 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 1, p. 69-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Obesity as a causal risk factor for deep venous thrombosis: a Mendelian randomization study
Klovaite, J., Benn, Marianne & Nordestgaard, Børge, May 2015, In: Journal of Internal Medicine. 277, 5, p. 573-584 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No evidence that genetically reduced 25-hydroxyvitamin D is associated with increased risk of ischaemic heart disease or myocardial infarction: a Mendelian randomization study
Brøndum-Jacobsen, P., Benn, Marianne, Afzal, Shoaib & Nordestgaard, Børge, Apr 2015, In: International Journal of Epidemiology. 44, 2, p. 651-661 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme concentrations of endogenous sex hormones, ischemic heart disease, and death in women
Benn, Marianne, Voss, S. S., Holmegard, H. N., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2 Feb 2015, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 2, p. 471-477 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Blood Pressure as Mediators From Obesity to Ischemic Heart Disease
Varbo, A., Benn, Marianne, Smith, G. D., Timpson, N. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2015, In: Circulation Research. 116, 4, p. 665-673 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study.
Dijkstra, A., Smolonska, J., van, D. B. M., Wijmenga, C., Zanen, P., Luinge, M., Platteel, M., Lammers, J., Dahlback, M., Tosh, K., Hiemstra, P., Sterk, P., Spira, A., Vestbo, J., Nordestgaard, Børge, Benn, Marianne, Nielsen, S., Dahl, Morten, Verschuren, W. & Picavet, H., 2015, In: P L o S Genetics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Huang, J., Howie, B., Mccarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H., Al Turki, S., Amuzu, A., Anderson, C. A., Anney, R., Antony, D., Artigas, M. S., Ayub, M., Bala, S., Barrett, J. C., Barroso, I. & 219 others, , 2015, In: Nature Communications. 6, 9 p., 8111.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subgroups at high risk for ischaemic heart disease:identification and validation in 67 000 individuals from the general population
Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dyson, G., Haase, C. L., Benn, Marianne, Nordestgaard, Børge & Sing, C. F., 2015, In: International Journal of Epidemiology. 44, 1, p. 117-128 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The UK10K project identifies rare variants in health and disease
Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R. B., Xu, C., Futema, M., Lawson, D., Iotchkova, V., Schiffels, S., Hendricks, A. E., Danecek, P., Li, R., Floyd, J., Wain, L. V., Barroso, I., Humphries, S. E., Hurles, M. E. & 319 others, , 2015, In: Nature. 526, 7571, p. 82-90 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Creatinine, eGFR and association with myocardial infarction, ischemic heart disease and early death in the general population
Sibilitz, K. L., Benn, Marianne & Nordestgaard, Børge, Nov 2014, In: Atherosclerosis. 237, 1, p. 67-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GENETICALLY REDUCED 25-HYDROXYVITAMIN D AND RISK OF ISCHEMIC HEART DISEASE AND MYOCARDIAL INFARCTION: A MENDELIAN RANDOMIZATION STUDY
Jacobsen, P., Benn, Marianne, Afzal, Shoaib & Nordestgaard, Børge, Aug 2014, In: Atherosclerosis. 235, 2, p. E66-E66 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Reply to Letters Regarding Article, “Elevated Remnant Cholesterol Causes Both Low-Grade Inflammation and Ischemic Heart Disease, Whereas Elevated Low-Density Lipoprotein Cholesterol Causes Ischemic Heart Disease Without Inflammation”
Varbo, A., Benn, Marianne, Tybjærg-Hansen, A. & Nordestgaard, Børge, 17 Jun 2014, In: Circulation. 129, 24, 1 p., e656.Research output: Contribution to journal › Comment/debate › Research
- Published
Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
LifeLines Cohort Study, L. C. S., 8 Apr 2014, In: PLoS ONE. 9, 4, 13 p., e91621.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remnant cholesterol as a cause of ischemic heart disease: evidence, definition, measurement, atherogenicity, high risk patients, and present and future treatment
Varbo, A., Benn, Marianne & Nordestgaard, Børge, Mar 2014, In: Pharmacology & Therapeutics. 141, 3, p. 358-367 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADH1B and ADH1C Genotype, Alcohol Consumption and Biomarkers of Liver Function: Findings from a Mendelian Randomization Study in 58,313 European Origin Danes
Lawlor, D. A., Benn, Marianne, Zuccolo, L., De Silva, N. M. G., Tybjaerg-Hansen, A., Smith, G. D. & Nordestgaard, Børge, 2014, In: PLOS ONE. 9, 12, p. 1-14 14 p., e114294.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antihypertensive treatment and risk of atrial fibrillation: a nationwide study
Marott, S. C. W., Nielsen, S. F., Benn, Marianne & Nordestgaard, Børge, 2014, In: European Heart Journal. 35, 18, p. 1205-2014 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous sex hormones and risk of venous thromboembolism in women and men
Holmegard, H. N., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Benn, Marianne, 2014, In: Journal of Thrombosis and Haemostasis. 12, 3, p. 297-305 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
Dijkstra, A. E., Smolonska, J., van den Berge, M., Wijmenga, C., Zanen, P., Luinge, M. A., Platteel, M., Lammers, J-W., Dahlback, M., Tosh, K., Hiemstra, P. S., Sterk, P. J., Spira, A., Vestbo, J., Nordestgaard, B., Benn, M., Nielsen, S. F., Dahl, M., Verschuren, W. M., Picavet, H. S. J. & 31 others, , 2014, In: PLOS ONE. 9, 4, p. 1-13 13 p., e91621.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
The Age-Specific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled Analysis
Singh, G. M., Danaei, G., Farzadfar, F., Stevens, G. A., Woodward, M., Wormser, D., Kaptoge, S., Whitlock, G., Qiao, Q., Lewington, S., Di Angelantonio, E., Vander Hoorn, S., Lawes, C. M. M., Ali, M. K., Mozaffarian, D., Ezzati, M., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth, Benn, Marianne & Nordestgaard, Børge, Jul 2013, In: P L o S One. 8, 7, p. 1-10 10 p., e65174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
Lawlor, D. A., Nordestgaard, Børge, Benn, Marianne, Zuccolo, L., Tybjærg-Hansen, Anne & Davey Smith, G., 14 Mar 2013, In: European Heart Journal (Online).Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts
Palmer, T. M., Nordestgaard, Børge, Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, G., Lawlor, D. A. & Timpson, N. J., 2013, In: B M J (Online). 347, p. 1-10 10 p., f4262.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated Remnant Cholesterol Causes Both Low-Grade Inflammation and Ischemic Heart Disease, Whereas Elevated Low-Density Lipoprotein Cholesterol Causes Ischemic Heart Disease Without Inflammation
Varbo, A., Benn, Marianne, Tybjærg-Hansen, Anne, Nordestgaard, Børge & Benn, Marianne, 2013, In: Circulation. 128, 12, p. 1298-1309 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in the parasympathetic signaling pathway in patients with reflex syncope
Holmegard, H. N., Benn, Marianne, Mehlsen, J. & Haunsø, Stig, 2013, In: Genetics and Molecular Research. 12, 3, p. 2601-2610 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of family history in patients with reflex syncope
Holmegard, H. N., Benn, Marianne, Kaijer, M. N., Haunsø, Stig & Mehlsen, J., 2013, In: Journal of Clinical Neuroscience. 20, 5, p. 692-696 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skin cancer as a marker of sun exposure associates with myocardial infarction, hip fracture and death from any cause
Brøndum-Jacobsen, P., Nordestgaard, Børge, Nielsen, S. F. & Benn, Marianne, 2013, In: International Journal of Epidemiology. 42, 5, p. 1486-1496 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles
Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study
Benn, Marianne, Tybjærg-Hansen, Anne, Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Benn, M., 16 Mar 2011, In: National Cancer Institute. Journal (Print). 103, 6, p. 508-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High platelet volume and increased risk of myocardial infarction: 39,531 participants from the general population
Klovaite, J., Benn, Marianne, Yazdanyar, S. & Nordestgaard, Børge, 1 Jan 2011, In: Journal of Thrombosis and Haemostasis. 9, 1, p. 49-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of Three Novel Candidate Genes in Arrhythmogenic Right Ventricular Cardiomyopathy
Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 2011, In: Genetic Testing and Molecular Biomarkers. 15, 4, p. 267-71 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Does elevated C-reactive protein increase atrial fibrillation risk? A Mendelian randomization of 47,000 individuals from the general population
Marott, S. C. W., Nordestgaard, Børge, Zacho, J., Friberg, Jens Birkedal, Jensen, G. B., Tybjærg-Hansen, Anne, Benn, Marianne & Benn, M., 31 Aug 2010, In: Journal of the American College of Cardiology. 56, 10, p. 789-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses
Benn, Marianne, Nordestgaard, Børge, Grande, P., Schnohr, P., Tybjærg-Hansen, Anne & Benn, M., 22 Jun 2010, In: Journal of the American College of Cardiology. 55, 25, p. 2833-42 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in the inwardly rectifying K channel subunits KCNJ3 (GIRK1) and KCNJ5 (GIRK4) in patients with sinus node dysfunction
Holmegard, H. N., Theilade, J., Benn, Marianne, Duno, M., Haunso, S., Svendsen, Jesper Hastrup, Holmegard, H. N., Theilade, J., Benn, M., Dunø, M., Haunso, S. & Svendsen, Jesper Hastrup, 1 Jan 2010, In: Cardiology. 115, 3, p. 176-81 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients--disease-causing or innocent bystanders?
Christensen, Alex Hørby, Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S., Svendsen, Jesper Hastrup, Christensen, A. H., Benn, M., Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, Jesper Hastrup, 1 Jan 2010, In: Cardiology. 115, 2, p. 148-54 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population.
Benn, Marianne, 2010, Københavns Universitet.Research output: Book/Report › Doctoral thesis › Research
- Published
Effect of ACE insertion/deletion and 12 other polymorphisms on clinical outcomes and response to treatment in the life study
Nordestgaard, Børge, Kontula, K., Benn, Marianne, Dahlöf, B., de Faire, U., Edelman, J. M., Eliasson, E., Fyhrquist, F., Hille, D. A., Ibsen, H., Lyle, P. A., Berg, K., Sandberg, M., Sethi, A. A., Wong, P. H., Os, I. & Benn, M., 2010, In: Pharmacogenetics and Genomics. 20, 2, p. 77-85 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review
Benn, Marianne, 2009, In: Atherosclerosis. 206, 1, p. 17-30 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting and nonfasting LDL cholesterol: to measure or calculate?
Nordestgaard, B. G. & Benn, Marianne, 2009, In: Clinical Chemistry. 55, 5, p. 845-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Missense variants in plakophilin-2 in arrhythmogenic right ventricular cardiomyopathy patients - disease - causing or innocent bystanders?
Christensen, A. H., Benn, Marianne, Tybjærg-Hansen, Anne, Haunso, S. & Svendsen, J. H., 2009, In: Cardiology. 115, 2, p. 148-154 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population
Ravn, L. S., Benn, Marianne, Nordestgaard, Børge, Sethi, A. A., Agerholm-Larsen, B., Jensen, G. B. & Tybjærg-Hansen, Anne, 2008, In: Pharmacogenetics and Genomics (Print Edition). 18, 6, p. 525-533 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common and rare alleles in apolipoprotein B contribute to plasma levels of low-density lipoprotein cholesterol in the general population
Benn, Marianne, Stene, M. C. A., Nordestgaard, Børge, Jensen, G. B., Steffensen, R. & Tybjærg-Hansen, Anne, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 3, p. 1038-1045 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme lipoprotein(a) levels and risk of myocardial infarction in the general population: the Copenhagen City Heart Study
Kamstrup, P. R., Benn, Marianne, Tybjaerg-Hansen, A. & Nordestgaard, B. G., 2008, In: Circulation. 117, 2, p. 176-184 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein(a) og risiko for myokardieinfarkt
Kamstrup, P. R., Benn, Marianne, Tybjaerg-Hansen, A. & Nordestgaard, B. G., 2008, In: Ugeskrift for læger. 170, p. 3226-4230 1004 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial haplogroups - Ischemic cardiovascular disease, other diseases, mortality, and longevity in the general population
Benn, Marianne, Schwartz, M., Nordestgaard, B. G. & Tybjaerg-Hansen, A., 2008, In: Circulation. 117, 19, p. 2492-2501 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pensionering af kreatininkinase myocardial band anbefales ikke
Ravkilde, J., Jurlander, Birgit, Andersen, L. K., Steffensen, R., Jorgensen, B., Jorgensen, J., Odum, L. & Benn, Marianne, 2008, In: Ugeskrift for læger. 170, 48, p. 3971-Research output: Contribution to journal › Journal article › Research › peer-review
ID: 47984237
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The UK10K project identifies rare variants in health and disease
Research output: Contribution to journal › Journal article › Research › peer-review
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Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Research output: Contribution to journal › Journal article › Research › peer-review
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Low LDL cholesterol, PCSK9 and HMGCR genetic variation, and risk of Alzheimer's disease and Parkinson's disease: Mendelian randomisation study
Research output: Contribution to journal › Journal article › Research › peer-review
Published