Ruth Frikke-Schmidt

Ruth Frikke-Schmidt

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. 2023
  2. Published

    Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

    EADB, E., GR@ACE study group, G. S. G., DEGESCO consortium, D. C., Demgene, D., EADI, E., GERAD, G. & Asian Parkinson’s Disease Genetics consortium, A. P. D. G. C., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 36, 11 p., e2302720120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Genetic Associations between Modifiable Risk Factors and Alzheimer Disease: [Inkl. correction]

    Luo, J., Thomassen, J. Q., Bellenguez, C., Grenier-Boley, B., De Rojas, I., Castillo, A., Parveen, K., Küçükali, F., Nicolas, A., Peters, O., Schneider, A., Dichgans, M., Rujescu, D., Scherbaum, N., Jürgen, D., Riedel-Heller, S., Hausner, L., Porcel, L. M., Düzel, E., Grimmer, T. & 76 others, Wiltfang, J., Heilmann-Heimbach, S., Moebus, S., Tegos, T., Scarmeas, N., Clarimon, J., Moreno, F., Pérez-Tur, J., Bullido, M. J., Pastor, P., Sánchez-Valle, R., Álvarez, V., Boada, M., García-González, P., Puerta, R., Mir, P., Real, L. M., Piñol-Ripoll, G., García-Alberca, J. M., Royo, J. L., Rodriguez-Rodriguez, E., Soininen, H., Kuulasmaa, T., De Mendonça, A., Mehrabian, S., Hort, J., Vyhnalek, M., Van Der Lee, S., Graff, C., Papenberg, G., Giedraitis, V., Boland, A., Bacq-Daian, D., Deleuze, J. F., Nicolas, G., Dufouil, C., Pasquier, F., Hanon, O., Debette, S., Grünblatt, E., Popp, J., Benussi, L., Galimberti, D., Arosio, B., Mecocci, P., Solfrizzi, V., Parnetti, L., Squassina, A., Tremolizzo, L., Borroni, B., Nacmias, B., Sorbi, S., Caffarra, P., Seripa, D., Rainero, I., Daniele, A., Masullo, C., Spalletta, G., Williams, J., Amouyel, P., Jessen, F., Kehoe, P., Magda, T., Rossi, G., Sánchez-Juan, P., Sleegers, K., Ingelsson, M., Andreassen, O. A., Hiltunen, M., Van Duijn, C., Sims, R., Van Der Flier, W., Ruiz, A., Ramirez, A., Lambert, J. C. & Frikke-Schmidt, Ruth, 2023, In: JAMA network open. 6, 5, 17 p., e2313734.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Neutrophil counts and cardiovascular disease

    Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 47, p. 4953-4964 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Short-Lived Antibody-Mediated Saliva Immunity against SARS-CoV-2 after Vaccination

    Madsen, J. R., Holm, B. E., Pérez-Alós, L., Bayarri-Olmos, R., Rosbjerg, A., Fogh, K., Pries-Heje, M. M., Møller, D. L., Hansen, Cecilie Bo, Heftdal, Line Dam, Hasselbalch, R. B., Hamm, S. R., Frikke-Schmidt, Ruth, Hilsted, Linda, Nielsen, Susanne Dam, Iversen, Kasper, Bundgård, Henning & Garred, Peter, 2023, In: Microbiology Spectrum. 11, 2, 11 p., e04947-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Modulation of inflammation by treatment with tocilizumab after out-of-hospital cardiac arrest and associations with clinical status, myocardial- and brain injury

    Meyer, M. A. S., Bjerre, M., Wiberg, S., Grand, J., Obling, L. E. R., Meyer, A. S. P., Josiassen, J., Frydland, M., Thomsen, J. H., Frikke-Schmidt, Ruth, Kjærgaard, Jesper & Hassager, Christian, 2023, In: Resuscitation. 184, 109676.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Red blood cell parameters in early childhood: a prospective cohort study

    Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Hansen, M. K., Sillesen, A. S., Vøgg, O. R. B., Raja, A. A., Rasmussen, I. J., Kamstrup, P. R., Benn, Marianne, Iversen, Kasper, Bundgård, Henning & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry and Laboratory Medicine. 61, 2, p. 275-284 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Significance of lipids, lipoproteins, and apolipoproteins during the first 14–16 months of life

    Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Rasmussen, I. J., Sillesen, A. S., B. Vøgg, R. O., Raja, A. A., Nordestgaard, Børge, Kamstrup, P. R., Iversen, Kasper, Bundgård, Henning, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 42, p. 4408-4418 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration

    Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Journal of Epidemiology. 38, 9, p. 985-994 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

    Obling, L. E. R., Beske, R. P., Meyer, M. A. S., Grand, J., Wiberg, Sebastian Christoph, Nyholm, B., Josiassen, J., Søndergaard, F. T., Mohr, T., Damm-Hejmdal, A., Bjerre, M., Frikke-Schmidt, Ruth, Folke, Fredrik, Møller, J. E., Kjærgaard, Jesper & Hassager, Christian, 2023, In: Intensive Care Medicine. 49, 12, p. 1467-1478 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Previous immunity shapes immune responses to SARS-CoV-2 booster vaccination and Omicron breakthrough infection risk

    Pérez-Alós, L., Hansen, Cecilie Bo, Almagro Armenteros, J. J., Madsen, J. R., Heftdal, Line Dam, Hasselbalch, R. B., Pries-Heje, M. M., Bayarri-Olmos, R., Jarlhelt, I., Hamm, S. R., Møller, D. L., Sørensen, E., Ostrowski, Sisse Rye, Frikke-Schmidt, Ruth, Hilsted, Linda, Bundgård, Henning, Nielsen, Susanne Dam, Iversen, Kasper & Garred, Peter, 2023, In: Nature Communications. 14, 1, 15 p., 5624.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    APOE and vascular disease: Sequencing and genotyping in general population cohorts

    Rasmussen, Katrine Laura, Luo, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Atherosclerosis. 385, 9 p., 117218.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Associations of Alzheimer Disease-Protective APOE Variants With Age-Related Macular Degeneration

    Rasmussen, Katrine Laura, Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2023, In: JAMA Ophthalmology. 141, 1, p. 13-21 9 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  14. Published

    Humoral and T-cell response 12 months after the first BNT162b2 vaccination in solid organ transplant recipients and controls: Kinetics, associated factors, and role of SARS-CoV-2 infection

    Rezahosseini, O., Hamm, S. R., Heftdal, L. D., Pérez-Alós, L., Møller, D. L., Perch, M., Madsen, J. R., Hald, A., Hansen, C. B., Armenteros, J. J. A., Pries-Heje, M. M., Hasselbalch, R. B., Fogh, K., Frikke-Schmidt, R., Hilsted, L. M., Sørensen, E., Ostrowski, S. R., Harboe, Z. B., Iversen, K., Bundgaard, H. & 4 others, Sørensen, Søren Schwartz, Rasmussen, A., Garred, Peter & Nielsen, Susanne Dam, 2023, In: Frontiers in Immunology. 13, 15 p., 1075423.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Plasma Concentrations of Calcium and Risk of Alzheimer Disease—Observational and Genetic Studies

    Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry. 69, 5, p. 525-536 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide: A Secondary Analysis of the Randomized LOOP Study

    Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Frikke-Schmidt, Ruth, Olesen, Morten Steen Salling, Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: Circulation. 147, 24, p. 1788-1797 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2022
  18. Published

    New insights into the genetic etiology of Alzheimer's disease and related dementias

    Bellenguez, C., Küçükali, F., Jansen, I. E., Kleineidam, L., Moreno-Grau, S., Amin, N., Naj, A. C., Campos-Martin, R., Grenier-Boley, B., Andrade, V., Holmans, P. A., Boland, A., Damotte, V., van der Lee, S. J., Costa, M. R., Kuulasmaa, T., Yang, Q., de Rojas, I., Bis, J. C., Yaqub, A. & 39 others, Prokic, I., Chapuis, J., Ahmad, S., Giedraitis, V., Aarsland, D., Garcia-Gonzalez, P., Abdelnour, C., Alarcón-Martín, E., Alcolea, D., Alegret, M., Alvarez, I., Álvarez, V., Armstrong, N. J., Tsolaki, A., Antúnez, C., Appollonio, I., Arcaro, M., Archetti, S., Pastor, A. A., Arosio, B., Athanasiu, L., Bailly, H., Banaj, N., Baquero, M., Barral, S., Beiser, A., Nielsen, S. F., Nordestgaard, Børge, Sáez, M. E., Frikke-Schmidt, Ruth, EADB, E., GR@ACE, G., DEGESCO, D., EADI, E., GERAD, G., Demgene, D., FinnGen, F., ADGC, A. & CHARGE, C., 2022, In: Nature Genetics. 54, 4, p. 412-436 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping

    Belloy, M. E., Eger, S. J., Le Guen, Y., Damotte, V., Ahmad, S., Ikram, M. A., Ramirez, A., Tsolaki, A. C., Rossi, G., Jansen, I. E., de Rojas, I., Parveen, K., Sleegers, K., Ingelsson, M., Hiltunen, M., Amin, N., Andreassen, O., Sánchez-Juan, P., Kehoe, P., Amouyel, P. & 9 others, Sims, R., Frikke-Schmidt, Ruth, van der Flier, W. M., Lambert, J. C., He, Z., Han, S. S., Napolioni, V., Greicius, M. D. & European Alzheimer & Dementia BioBank (EADB), E. A. &. D. B. (., 2022, In: Alzheimer's research & therapy. 14, 1, 17 p., 22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Self-Reported Long COVID and Its Association with the Presence of SARS-CoV-2 Antibodies in a Danish Cohort up to 12 Months after Infection

    Fogh, K., Larsen, T. G., Hansen, Cecilie Bo, Hasselbalch, R. B., Eriksen, A. R. R., Bundgård, Henning, Frikke-Schmidt, Ruth, Hilsted, L. M., Østergaard, L., Johansen, I. S., Hageman, Ida, Garred, Peter & Iversen, Kasper, 2022, In: Microbiology Spectrum. 10, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Serum cobalamin in children with moderate acute malnutrition in Burkina Faso: Secondary analysis of a randomized trial

    Friis, Henrik, Cichon, B., Fabiansen, C., Iuel-Brockdorff, A., Yaméogo, C. W., Ritz, C., Frikke-Schmidt, Ruth, Briend, A., Michaelsen, Kim F., Christensen, Vibeke Brix, Filteau, S. & Olsen, Mette Frahm, 2022, In: P L o S Medicine (Online). 19, 3, 18 p., e1003943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Observational and genetic studies of C-reactive protein levels and risk of Alzheimer's disease

    Frikke-Schmidt, Ruth, Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Thomassen, J. Q., 2022, In: Alzheimer's and Dementia. 18, 12, p. 2734-2735

    Research output: Contribution to journalComment/debateResearchpeer-review

  23. Published

    Decline in Antibody Concentration 6 Months After Two Doses of SARS-CoV-2 BNT162b2 Vaccine in Solid Organ Transplant Recipients and Healthy Controls

    Hamm, S. R., Møller, D. L., Pérez-Alós, L., Hansen, C. B., Pries-Heje, M. M., Heftdal, L. D., Hasselbalch, R. B., Fogh, K., Madsen, J. R., Almagro Armenteros, J. J., Knudsen, A. D., Poulsen, J. R., Frikke-Schmidt, R., Hilsted, L. M., Sørensen, E., Ostrowski, S. R., Harboe, Z. B., Perch, M., Sørensen, S. S., Rasmussen, A. & 4 others, Bundgård, Henning, Garred, Peter, Iversen, Kasper & Nielsen, Susanne Dam, 2022, In: Frontiers in Immunology. 13, 10 p., 832501.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Antibody responses and risk factors associated with impaired immunological outcomes following two doses of BNT162b2 COVID-19 vaccination in patients with chronic pulmonary diseases

    Harboe, Z. B., Hamm, S. R., Pérez-Alós, L., Sivapalan, P., Priemé, H., Wilcke, T., Kjeldgaard, P., Shaker, S., Svorre Jordan, A., Møller, D. L., Heftdal, L. D., Madsen, J. R., Bayarri-Olmos, R., Hansen, C. B., Pries-Heje, M. M., Hasselbalch, R. B., Fogh, K., Armenteros, J. J. A., Hilsted, L., Sørensen, E. & 10 others, Lindegaard, Birgitte, Browatzki, A., Biering-Sørensen, Tor, Frikke-Schmidt, Ruth, Ostrowski, Sisse Rye, Iversen, Kasper, Bundgård, Henning, Nielsen, Susanne Dam, Garred, Peter & Jensen , Jens-Ulrik Stæhr , 2022, In: BMJ Open Respiratory Research. 9, 1, 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    C-reactive protein levels and risk of dementia — Observational and genetic studies of 111,242 individuals from the general population

    Hegazy, S. H., Thomassen, J. Q., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Alzheimer's & Dementia. 18, 11, p. 2262-2271 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Associations between primary care electrocardiography and non-Alzheimer dementia

    Isaksen, Jonas L., Ghouse, Jonas, Skov, M. W., Olesen, Morten Steen Salling, Holst, A. G., Pietersen, A., Nielsen, J. B., Maier, A. M., Graff, C., Frikke-Schmidt, Ruth & Kanters, Jørgen K., 10 Jul 2022, In: Journal of Stroke & Cerebrovascular Diseases. 31, 9, 7 p., 106640.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Physical activity in leisure time and at work and risk of dementia: A prospective cohort study of 117,616 individuals

    Juul Rasmussen, I., Rasmussen, Katrine Laura, Thomassen, J. Q., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Atherosclerosis. 360, p. 53-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 43235093