Ruth Frikke-Schmidt

Ruth Frikke-Schmidt

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. Published

    Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans

    Oldoni, F., van Capelleveen, J. C., Dalila, N., Wolters, J. C., Heeren, J., Sinke, R. J., Hui, D. Y., Dallinga-Thie, G. M., Frikke-Schmidt, Ruth, Hovingh, K. G., van de Sluis, B., Tybjærg-Hansen, Anne & Kuivenhoven, J. A., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 7, p. 1440-1453 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

    Obling, L. E. R., Beske, R. P., Meyer, M. A. S., Grand, J., Wiberg, Sebastian Christoph, Nyholm, B., Josiassen, J., Søndergaard, F. T., Mohr, T., Damm-Hejmdal, A., Bjerre, M., Frikke-Schmidt, Ruth, Folke, Fredrik, Møller, J. E., Kjærgaard, Jesper & Hassager, Christian, 2023, In: Intensive Care Medicine. 49, 12, p. 1467-1478 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Effect of prehospital high-dose glucocorticoid on hemodynamics in patients resuscitated from out-of-hospital cardiac arrest: a sub-study of the STEROHCA trial

    Obling, L. E. R., Beske, R. P., Meyer, M. A. S., Grand, J., Wiberg, Sebastian Christoph, Mohr, T., Damm-Hejmdal, A., Forman, Julie Lyng, Frikke-Schmidt, Ruth, Folke, Fredrik, Møller, J. E., Kjærgaard, Jesper & Hassager, Christian, 2024, In: Critical Care. 28, 1, 12 p., 28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Copy number variation in glutathione S-transferases M1 and T1 and ischemic vascular disease: four studies and meta-analyses

    Nørskov, M. S., Frikke-Schmidt, Ruth, Loft, Steffen, Sillesen, Henrik, Grande, P., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: Circulation: Cardiovascular Genetics. 4, 4, p. 418-28 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published
  6. Published

    Leg vascular and skeletal muscle mitochondrial adaptations to aerobic high-intensity exercise training are enhanced in the early postmenopausal phase

    Nyberg, M. P., Egelund, J., djc739, djc739, Roland, Caroline Borup, Hansen, K. M. B. E., Hergel, I. F., Valbak-Andersen, N., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Bangsbo, Jens & Hellsten, Ylva, 2017, In: Journal of Physiology. 595, 9, p. 2969-2983 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    High-throughput genotyping of copy number variation in glutathione S-transferases M1 and T1 using real-time PCR in 20,687 individuals

    Norskov, M. S., Frikke-Schmidt, Ruth, Loft, Steffen & Tybjærg-Hansen, Anne, 2009, In: Clinical Biochemistry. 42, 3, p. 201-209 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Body mass index and risk of Alzheimer's disease: A mendelian randomization study of 399,536 individuals

    Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jul 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 7, p. 2310-2320 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: Cohort studies and meta-analyses of 362,338 individuals

    Nordestgaard, L. T., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: BMC Medicine. 16, 11 p., 39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease

    Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Dec 2015, In: Alzheimer's & Dementia. 11, 12, p. 1430-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration

    Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Journal of Epidemiology. 38, 9, p. 985-994 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Elevated Apolipoprotein A1 and HDL Cholesterol Associated with Age-related Macular Degeneration: 2 Population Cohorts

    Nordestgaard, L. T., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 16 Jun 2021, In: The Journal of clinical endocrinology and metabolism. 106, 7, p. e2749-e2758 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Long-term Benefits and Harms Associated with Genetic Cholesteryl Ester Transfer Protein Deficiency in the General Population

    Nordestgaard, L. T., Christoffersen, M., Lauridsen, B. K., Afzal, Shoaib, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 2022, In: JAMA Cardiology. 7, 1, p. 55-64

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Shared Risk Factors between Dementia and Atherosclerotic Cardiovascular Disease

    Nordestgaard, L. T., Christoffersen, M. & Frikke-Schmidt, Ruth, 2022, In: International Journal of Molecular Sciences. 23, 17, 9777.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Triglycerides as a Shared Risk Factor between Dementia and Atherosclerotic Cardiovascular Disease: A Study of 125 727 Individuals

    Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 1, p. 245-255 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Genetic variation in ABCA1 and risk of all-cause dementia, age-related macular degeneration, and ischemic heart disease

    Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Atherosclerosis. 331, p. E38-E39 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  17. Published

    Self-reported and genetically predicted coffee consumption and smoking in dementia: A Mendelian randomization study

    Nordestgaard, A. T., Nordestgaard, Børge, Frikke-Schmidt, Ruth, Juul Rasmussen, I. & Bojesen, Stig Egil, 2022, In: Atherosclerosis. 348, p. 36-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Red blood cell parameters in early childhood: a prospective cohort study

    Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Hansen, M. K., Sillesen, A. S., Vøgg, O. R. B., Raja, A. A., Rasmussen, I. J., Kamstrup, P. R., Benn, Marianne, Iversen, Kasper, Bundgård, Henning & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry and Laboratory Medicine. 61, 2, p. 275-284 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Significance of lipids, lipoproteins, and apolipoproteins during the first 14–16 months of life

    Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Rasmussen, I. J., Sillesen, A. S., B. Vøgg, R. O., Raja, A. A., Nordestgaard, Børge, Kamstrup, P. R., Iversen, Kasper, Bundgård, Henning, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 42, p. 4408-4418 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Coagulation parameters in the newborn and infant: The Copenhagen Baby Heart and COMPARE studies

    Nielsen, S. T., Strandkjær, N., Juul Rasmussen, I., Hansen, M. K., Lytsen, R. M., Kamstrup, P. R., Rode, L., Goetze, Jens P. , Iversen, Kasper, Bundgård, Henning & Frikke-Schmidt, Ruth, 2022, In: Clinical Chemistry and Laboratory Medicine. 60, 2, p. 261-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    High-sensitive C-reactive protein and homocysteine levels in patients with newly diagnosed bipolar disorder, their first-degree relatives, and healthy control persons-Results from a clinical study

    Nielsen, M. Ø., Petersen, N. A., Coello, K., Stanislaus, S., Melbye, S. A., Kjærstad, H. L., Sletved, K. S. O., Frikke-Schmidt, Ruth, McIntyre, R. S., Vinberg, Maj & Kessing, Lars Vedel, 2020, In: European psychiatry : the journal of the Association of European Psychiatrists. 63, 1, p. e103

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Serum soluble CD163 predicts risk of type 2 diabetes in the general population

    Møller, H. J., Frikke-Schmidt, Ruth, Moestrup, S., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Feb 2011, In: Clinical Chemistry. 57, 2, p. 291-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations

    Motazedi, E., Cheng, W., Thomassen, J. Q., Frei, O., Rongve, A., Athanasiu, L., Bahrami, S., Shadrin, A., Ulstein, I., Stordal, E., Brækhus, A., Saltvedt, I., Sando, S. B., O'Connell, K. S., Hindley, G., Van Der Meer, D., Bergh, S., Nordestgaard, B. G., Tybjærg-Hansen, A., Brthen, G. & 10 others, Pihlstrm, L., Djurovic, S., Frikke-Schmidt, Ruth, Fladby, T., Aarsland, D., Selbæk, G., Seibert, T. M., Dale, A. M., Fan, C. C. & Andreassen, O. A., 2022, In: Journal of Alzheimer's Disease. 88, 4, p. 1533-1544

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Markers of Kidney Function in Early Childhood and Association With Maternal Comorbidity

    Mohr Lytsen, R., Taageby Nielsen, S., Kongsgaard Hansen, M., Strandkjær, N., Juul Rasmussen, I., Axelsson Raja, A., Vøgg, R. O., Sillesen, A. S., Kamstrup, P. R., Schmidt, I. M., Iversen, Kasper, Bundgård, Henning & Frikke-Schmidt, Ruth, 2022, In: JAMA network open. 5, 11, e2243146.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Stroke genetics informs drug discovery and risk prediction across ancestries

    Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y. C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., Parodi, L. & 45 others, Bae, H. J., Chauhan, G., Chong, M. R., Tomppo, L., Akinyemi, R., Roshchupkin, G. V., Habib, N., Jee, Y. H., Thomassen, J. Q., Abedi, V., Cárcel-Márquez, J., Nygaard, M., Leonard, H. L., Yang, C., Yonova-Doing, E., Knol, M. J., Lewis, A. J., Judy, R. L., Ago, T., Amouyel, P., Armstrong, N. D., Bakker, M. K., Bartz, T. M., Bennett, D. A., Bis, J. C., Bordes, C., Børte, S., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth, PRECISEQ Consortium, P. C., FinnGen Consortium, F. C., NINDS Stroke Genetics Network (SiGN), N. S. G. N. (., MEGASTROKE Consortium, M. C., SIREN Consortium, S. C., China Kadoorie Biobank Collaborative Group, C. K. B. C. G., VA Million Veteran Program, V. M. V. P., International Stroke Genetics Consortium (ISGC), I. S. G. C. (., BioBank Japan, B. J., CHARGE Consortium, C. C., GIGASTROKE Consortium, G. C., COMPASS Consortium, C. C., INVENT Consortium, I. C., Dutch Parelsnoer Initiative (PSI) Cerebrovascular Disease Study Group, D. P. I. (. C. D. S. G. & Estonian Biobank, E. B., 2022, In: Nature. 611, 7934, p. 115-123 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 43235093