Ruth Frikke-Schmidt

Ruth Frikke-Schmidt

Clinical Professor

Member of:

  • Clinical Biochemistry


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  1. Published

    Hdl cholesterol and non-cardiovascular disease: A narrative review

    Kjeldsen, E. W., Nordestgaard, L. T. & Frikke-Schmidt, Ruth, 2021, In: International Journal of Molecular Sciences. 22, 9, 4547.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    ABCA7 and risk of dementia and vascular disease in the Danish population

    Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Plasma high-density lipoprotein cholesterol and risk of dementia: observational and genetic studies

    Kjeldsen, E. W., Thomassen, J. Q., Juul Rasmussen, I., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Cardiovascular Research. 118, 5, p. 1330-1343 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Reevaluating the Role of High-Density Lipoprotein Cholesterol: New Perspectives on Cardiovascular Disease and Alzheimer Disease

    Kjeldsen, E. W., Luo, J., Nordestgaard, L. T., Sandau, N. & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry. 69, 12, p. 1329-1332 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease – Insights from randomized clinical trials and human genetics

    Kjeldsen, E. W., Thomassen, J. Q. & Frikke-Schmidt, Ruth, 2022, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1867, 1, 7 p., 159063.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors

    Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, Møller, J. A., Boldsen, J. K., Burgdorf, Kristoffer Sølvsten, Kessing, Lars Vedel, Handgaard, L. J., Thørner, L. W., Didriksen, Maria, Nyegaard, Mette, Grarup, Niels, Ødum, Niels, Johansson, P. I., Jennum, Poul, Frikke-Schmidt, Ruth, Berger, S. S., Brunak, Søren, Jacobsen, Søren, Hansen, Thomas Folkmann, Lundquist, T. K., Hansen, Torben, Sørensen, Torben Lykke, Sigsgaard, T., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Ullum, H., Rostgaard, K., Sørensen, E., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye & Erikstrup, C., 2024, In: Communications Medicine. 4, 15 p., 50.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Admission Leukocyte Count is Associated with Late Cardiogenic Shock Development and All-Cause 30-Day Mortality in Patients with St-Elevation Myocardial Infarction

    Klein, A., Wiberg, S., Hassager, Christian, Winther-Jensen, M., Frikke-Schmidt, Ruth, Bang, L. E., Lindholm, M. G., Holmvang, Lene, Moeller-Helgestad, O., Ravn, H. B., Jensen, L. O., Kjærgaard, J., Møller, J. E. & Frydland, M., 2020, In: Shock. 53, 3, p. 299-306 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer

    Kobberø Lauridsen, B., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2017, In: International Journal of Epidemiology. 46, 6, p. 1777-1785

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Vegetarian or vegan diets and blood lipids: a meta-analysis of randomized trials

    Koch, C. A., Kjeldsen, E. W. & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 28, p. 2609–2622 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Occupational lifting and risk of hypertension, stratified by use of anti-hypertensives and age - a cross-sectional and prospective cohort study

    Korshøj, M., Hannerz, H., Frikke-Schmidt, Ruth, Marott, J. L., Schnohr, P., Clays, E. & Holtermann, A., 2021, In: BMC Public Health. 21, 1, 721.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Validation of a novel automated system, Fluispotter®, for serial sampling of dried blood spots

    Krogh, Jesper, Plomgaard, Peter Stendahl, Frikke-Schmidt, Ruth, Velschow, S., Johannesen, Jesper, Hilsted, L. M., Schrøder, M. & Feldt-Rasmussen, Ulla, 2023, In: Endocrine Connections. 12, 7, 9 p., e230087.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Waning humoral and cellular immunity after COVID-19 vaccination in patients with psoriasis treated with methotrexate and biologics: A cohort study

    Kvist-Hansen, A., Pérez-Alós, L., Al-Sofi, R. F., Heftdal, L. D., Hamm, S. R., Møller, D. L., Pries-Heje, M. M., Fogh, K., Bo Hansen, C., Bo Hasselbalch, R., Madsen, J. R., Armenteros, J. J. A., Frikke-Schmidt, R., Hilsted, L., Sørensen, E., Ostrowski, S. R., Bundgaard, H., Nielsen, S. D., Iversen, K., Zachariae, C. & 2 others, Garred, Peter & Skov, Lone, 2023, In: British Journal of Dermatology. 188, 5, p. 661-669 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease

    Lauridsen, B. K., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2015, In: European Heart Journal. 36, 25, p. 1601-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Cohort profile: Copenhagen Hospital Biobank - Cardiovascular Disease Cohort (CHB-CVDC): Construction of a large-scale genetic cohort to facilitate a better understanding of heart diseases

    Laursen, I. H., Banasik, K., Haue, A. D., Petersen, O., Holm, P. C., Westergaard, D., Bundgaard, H., Brunak, S., Frikke-Schmidt, R., Holm, H., Sørensen, E., Thorner, L. W., Larsen, M. A. H., Schwinn, M., Køber, L., Torp-Pedersen, C., Ostrowski, S. R., Erikstrup, C., Nyegaard, M., Stefansson, H. & 11 others, Gylfason, A., Zink, F., Walters, G. B., Oddsson, A., Thorleifsson, G., Masson, G., Thorsteinsdottir, U., Gudbjartsson, D., Pedersen, Ole Birger Vesterager, Stefansson, K. & Ullum, H., 2021, In: BMJ Open. 11, 12, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis

    Laursen, J. H., Søndergaard, H. B., Albrechtsen, Anders, Frikke-Schmidt, Ruth, Koch-Henriksen, N., Sørensen, Per Soelberg, Sellebjerg, Finn Thorup & Oturai, A. B., 2015, In: Multiple Sclerosis Journal. 21, 11, p. 1414-1422 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Association of MGMT and BIN1 genes with Alzheimer's disease risk across sex and APOE ε4 status

    Le Borgne, J., Amouyel, P., Andreassen, O., Frikke-Schmidt, Ruth, Hiltunen, M., Ingelsson, M., Ramirez, A., Rossi, G., Ruiz, A., Sanchez-Juan, P., Sims, R., Sleegers, K., Tsolaki, M., van der Lee, S. J., Williams, J., Lambert, J. C. & Bellenguez, C., 2024, In: Alzheimer's and Dementia. 20, 3, p. 2282-2284 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  17. Published

    Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

    EADB, E., GR@ACE study group, G. S. G., DEGESCO consortium, D. C., Demgene, D., EADI, E., GERAD, G. & Asian Parkinson’s Disease Genetics consortium, A. P. D. G. C., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 36, 11 p., e2302720120.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Association of Rare APOE Missense Variants V236E and R251G with Risk of Alzheimer Disease

    Le Guen, Y., Belloy, M. E., Grenier-Boley, B., De Rojas, I., Castillo-Morales, A., Jansen, I., Nicolas, A., Bellenguez, C., Dalmasso, C., Küçükali, F., Eger, S. J., Rasmussen, K. L., Thomassen, J. Q., Deleuze, J. F., He, Z., Napolioni, V., Amouyel, P., Jessen, F., Kehoe, P. G., Van Duijn, C. & 89 others, Tsolaki, M., Sánchez-Juan, P., Sleegers, K., Ingelsson, M., Rossi, G., Hiltunen, M., Sims, R., Van Der Flier, W. M., Ramirez, A., Andreassen, O. A., Frikke-Schmidt, Ruth, Williams, J., Ruiz, A., Lambert, J. C., Greicius, M. D., Arosio, B., Benussi, L., Boland, A., Borroni, B., Caffarra, P., Daian, D., Daniele, A., Debette, S., Dufouil, C., Düzel, E., Galimberti, D., Giedraitis, V., Grimmer, T., Graff, C., Grünblatt, E., Hanon, O., Hausner, L., Heilmann-Heimbach, S., Holstege, H., Hort, J., Jürgen, D., Kuulasmaa, T., Van Der Lugt, A., Masullo, C., Mecocci, P., Mehrabian, S., De Mendonça, A., Moebus, S., Nacmias, B., Nicolas, G., Olaso, R., Papenberg, G., Parnetti, L., Pasquier, F., Peters, O., Pijnenburg, Y. A. L., Popp, J., Rainero, I., Ramakers, I., Riedel-Heller, S., Scarmeas, N., Scheltens, P., Scherbaum, N., Schneider, A., Seripa, D., Soininen, H., Solfrizzi, V., Spalletta, G., Squassina, A., Van Swieten, J., Tegos, T. J., Tremolizzo, L., Verhey, F., Vyhnalek, M., Wiltfang, J., Boada, M., García-González, P., Puerta, R., Real, L. M., Álvarez, V., Bullido, M. J., Clarimon, J., García-Alberca, J. M., Mir, P., Moreno, F., Pastor, P., Piñol-Ripoll, G., Molina-Porcel, L., Pérez-Tur, J., Rodríguez-Rodríguez, E., Royo, J. L., Sánchez-Valle, R., Dichgans, M. & Rujescu, D., 2022, In: JAMA Neurology. 79, 7, p. 652-663 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta-analysis consisting 2.8 million adults with 57 294 cases of dementia

    Lee, C. M. Y., Woodward, M., Batty, G. D., Beiser, A. S., Bell, S., Berr, C., Bjertness, E., Chalmers, J., Clarke, R., Dartigues, J. F., Davis-Plourde, K., Debette, S., Di Angelantonio, E., Feart, C., Frikke-Schmidt, R., Gregson, J., Haan, M. N., Hassing, L. B., Hayden, K. M., Hoevenaar-Blom, M. P. & 26 others, Kaprio, J., Kivimaki, M., Lappas, G., Larson, E. B., LeBlanc, E. S., Lee, A., Lui, L. Y., Moll van Charante, E. P., Ninomiya, T., Nordestgaard, L. T., Ohara, T., Ohkuma, T., Palviainen, T., Peres, K., Peters, R., Qizilbash, N., Richard, E., Rosengren, A., Seshadri, S., Shipley, M., Singh-Manoux, A., Strand, B. H., van Gool, W. A., Vuoksimaa, E., Yaffe, K. & Huxley, R. R., Apr 2020, In: Obesity Reviews. 21, 4, 14 p., e12989.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Exome-wide association study of plasma lipids in >300,000 individuals

    Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, Boehnke, M., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., Brandslund, I., Brown, M., Busonero, F., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. E., Chen, Y. D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Connell, J. M., Cucca, F., Cupples, L. A., Damrauer, S. M., Davies, G., Deary, I. J., Dedoussis, G., Denny, J. C., Dominiczak, A., Dubé, M. P., Ebeling, T., Eiriksdottir, G., Esko, T., Farmaki, A. E., Feitosa, M. F., Ferrario, M., Ferrieres, J., Ford, I., Fornage, M., Franks, P. W., Frayling, T. M., Frikke-Schmidt, Ruth, Fritsche, L. G., Frossard, P., Fuster, V., Ganesh, S. K., Gao, W., Garcia, M. E., Gieger, C., Giulianini, F., Goodarzi, M. O., Grallert, H., Grarup, Niels, Groop, L., Grove, M. L., Gudnason, V., Hansen, Torben, Harris, T. B., Hayward, C., Hirschhorn, J. N., Holmen, O. L., Huffman, J., Huo, Y., Hveem, K., Jabeen, S., Jackson, A. U., Jakobsdottir, J., Jarvelin, M. R., Jensen, G. B., Jørgensen, M. E., Jukema, J. W., Justesen, Johanne Marie, Kamstrup, P. R., Kanoni, S., Karpe, F., Kee, F., Khera, A. V., Klarin, D., Koistinen, H. A., Kooner, J. S., Kooperberg, C., Kuulasmaa, K., Kuusisto, J., Laakso, M., Lakka, T., Langenberg, C., Langsted, A., Launer, L. J., Lauritzen, T., MLiewald, D. C., Lin, L. A., Linneberg, Allan René, Loos, R. J. F., Lu, Y., Lu, X., Mägi, R., Malarstig, A., Manichaikul, A., Manning, A. K., Mäntyselkä, P., Marouli, E., Masca, N. G. D., Maschio, A., Meigs, J. B., Melander, O., Metspalu, A., Morris, A. P., Morrison, A. C., Mulas, A., Müller-Nurasyid, M., Munroe, P. B., Neville, M. J., Nielsen, S. F., Nielsen, J. B., Nordestgaard, Børge, Ordovas, J. M., Mehran, R., O'Donnell, C. J., Orho-Melander, M., Molony, C. M., Muntendam, P., Padmanabhan, S., Palmer, C. N. A., Pasko, D., Patel, A. P., Pedersen, Oluf Borbye, Perola, M., Peters, A., Pisinger, C., Pistis, G., Polasek, O., Poulter, N., Psaty, B. M., Rader, D. J., Rasheed, A., Rauramaa, R., Reilly, D. F., Reiner, A. P., Renström, F., Rich, S. S., Ridker, P. M., Rioux, J. D., Robertson, N. R., Roden, D. M., Rotter, J. I., Rudan, I., Salomaa, V., Samani, N. J., Sanna, S., Sattar, N., Schmidt, E. M., Scott, R. A., Sever, P., Sevilla, R. S., Shaffer, C. M., Sim, X., Sivapalaratnam, S., Small, K. S., Smith, A. V., Smith, B. H., Somayajula, S., Southam, L., Spector, T. D., Speliotes, E. K., Starr, J. M., Stirrups, K. E., Stitziel, N., Strauch, K., Stringham, H. M., Surendran, P., Tada, H., Tall, A. R., Tang, H., Tardif, J. C., Taylor, K. D., Trompet, S., Tsao, P. S., Tuomilehto, J., Tybjærg-Hansen, Anne, Zuydam, N. R. V., Varbo, A., Varga, T. V., Virtamo, J., Waldenberger, M., Wang, N., Wareham, N. J., Warren, H. R., Weeke, P. E., Weinstock, J., Wessel, J., Wilson, J. G., Wilson, P. W. F., Xu, M., Yaghootkar, H., Young, R., Zeggini, E., Zhang, H., Zheng, N. S., Zhang, W., Zhang, Y., Zhou, W., Zhou, Y., Zoledziewska, M., Howson, J. M. M., Danesh, J., McCarthy, M. I., Cowan, C. A., Abecasis, G., Deloukas, P., Musunuru, K., Willer, C. J., Kathiresan, S. & V Varga, Tibor, 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  21. Published

    Aerobic exercise training lowers platelet reactivity and improves platelet sensitivity to prostacyclin in pre- and postmenopausal women

    Lundberg Slingsby, M. H., Nyberg, M. P., Egelund, J., djc739, djc739, Frikke-Schmidt, Ruth, Kirkby, N. S. & Hellsten, Ylva, 2017, In: Journal of Thrombosis and Haemostasis. 15, 12, p. 2419-2431 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease

    Lundegaard, C., Tybjærg-Hansen, Anne, Grande, P. & Frikke-Schmidt, Ruth, 1 Dec 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. E500-10

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Neutrophil counts and cardiovascular disease

    Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 47, p. 4953-4964 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genetic Associations between Modifiable Risk Factors and Alzheimer Disease: [Inkl. correction]

    Luo, J., Thomassen, J. Q., Bellenguez, C., Grenier-Boley, B., De Rojas, I., Castillo, A., Parveen, K., Küçükali, F., Nicolas, A., Peters, O., Schneider, A., Dichgans, M., Rujescu, D., Scherbaum, N., Jürgen, D., Riedel-Heller, S., Hausner, L., Porcel, L. M., Düzel, E., Grimmer, T. & 76 others, Wiltfang, J., Heilmann-Heimbach, S., Moebus, S., Tegos, T., Scarmeas, N., Clarimon, J., Moreno, F., Pérez-Tur, J., Bullido, M. J., Pastor, P., Sánchez-Valle, R., Álvarez, V., Boada, M., García-González, P., Puerta, R., Mir, P., Real, L. M., Piñol-Ripoll, G., García-Alberca, J. M., Royo, J. L., Rodriguez-Rodriguez, E., Soininen, H., Kuulasmaa, T., De Mendonça, A., Mehrabian, S., Hort, J., Vyhnalek, M., Van Der Lee, S., Graff, C., Papenberg, G., Giedraitis, V., Boland, A., Bacq-Daian, D., Deleuze, J. F., Nicolas, G., Dufouil, C., Pasquier, F., Hanon, O., Debette, S., Grünblatt, E., Popp, J., Benussi, L., Galimberti, D., Arosio, B., Mecocci, P., Solfrizzi, V., Parnetti, L., Squassina, A., Tremolizzo, L., Borroni, B., Nacmias, B., Sorbi, S., Caffarra, P., Seripa, D., Rainero, I., Daniele, A., Masullo, C., Spalletta, G., Williams, J., Amouyel, P., Jessen, F., Kehoe, P., Magda, T., Rossi, G., Sánchez-Juan, P., Sleegers, K., Ingelsson, M., Andreassen, O. A., Hiltunen, M., Van Duijn, C., Sims, R., Van Der Flier, W., Ruiz, A., Ramirez, A., Lambert, J. C. & Frikke-Schmidt, Ruth, 2023, In: JAMA network open. 6, 5, 17 p., e2313734.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Blood Leukocyte Counts in Alzheimer Disease

    Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: JAMA network open. 5, 10, 14 p., E2235648.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 43235093