Ruth Frikke-Schmidt

Ruth Frikke-Schmidt

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. Published

    Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors

    Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, Møller, J. A., Boldsen, J. K., Burgdorf, Kristoffer Sølvsten, Kessing, Lars Vedel, Handgaard, L. J., Thørner, L. W., Didriksen, Maria, Nyegaard, Mette, Grarup, Niels, Ødum, Niels, Johansson, P. I., Jennum, Poul, Frikke-Schmidt, Ruth, Berger, S. S., Brunak, Søren, Jacobsen, Søren, Hansen, Thomas Folkmann, Lundquist, T. K., Hansen, Torben, Sørensen, Torben Lykke, Sigsgaard, T., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Ullum, H., Rostgaard, K., Sørensen, E., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye & Erikstrup, C., 2024, In: Communications Medicine. 4, 15 p., 50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Lipid measurements in the management of cardiovascular diseases: Practical recommendations a scientific statement from the national lipid association writing group

    Wilson, P. W. F., Jacobson, T. A., Martin, S. S., Jackson, E. A., Le, N. A., Davidson, M. H., Vesper, H. W., Frikke-Schmidt, Ruth, Ballantyne, C. M. & Remaley, A. T., 2021, In: Journal of Clinical Lipidology. 15, 5, p. 629-648

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease: A Note on Mendelian Randomization Studies

    Würtz, P., Kangas, A. J., Soininen, P., Lehtimäki, T., Kähönen, M., Viikari, J. S., Raitakari, O. T., Järvelin, M., Davey Smith, G., Ala-Korpela, M., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2013, In: Journal of the American College of Cardiology. 62, 20, p. 1906-8 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Lipoprotein(a) Levels at Birth and in Early Childhood: The COMPARE Study

    Strandkjær, N., Hansen, M. K., Nielsen, S. T., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Nordestgaard, Børge, Tabor, Ann, Bundgård, Henning, Iversen, Kasper & Kamstrup, P. R., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 2, p. 324-335 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Long-term Benefits and Harms Associated with Genetic Cholesteryl Ester Transfer Protein Deficiency in the General Population

    Nordestgaard, L. T., Christoffersen, M., Lauridsen, B. K., Afzal, Shoaib, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 2022, In: JAMA Cardiology. 7, 1, p. 55-64

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

    Jørgensen, A. B., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jul 2014, In: New England Journal of Medicine. 371, 1, p. 32-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease

    Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Dec 2015, In: Alzheimer's & Dementia. 11, 12, p. 1430-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published
  9. Published

    Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study

    Benn, Marianne, Tybjærg-Hansen, Anne, Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Benn, M., 16 Mar 2011, In: National Cancer Institute. Journal (Print). 103, 6, p. 508-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Markers of Kidney Function in Early Childhood and Association With Maternal Comorbidity

    Mohr Lytsen, R., Taageby Nielsen, S., Kongsgaard Hansen, M., Strandkjær, N., Juul Rasmussen, I., Axelsson Raja, A., Vøgg, R. O., Sillesen, A. S., Kamstrup, P. R., Schmidt, I. M., Iversen, Kasper, Bundgård, Henning & Frikke-Schmidt, Ruth, 2022, In: JAMA network open. 5, 11, e2243146.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Measurement of amyloid-β 1-42 in cerebrospinal fluid: a comparison of the second generation Elecsys and INNOTEST

    Dimopoulos, K., Simonsen, A. H., Gramkow, M. H., Schrøder, M., Jørgensen, Niklas Rye, Rode, L., Frikke-Schmidt, Ruth, Hilsted, Linda & Hasselbach, S. G., 2023, In: Clinical Chemistry and Laboratory Medicine. 61, 9, p. E182-E185 4 p.

    Research output: Contribution to journalComment/debateResearch

  12. Published

    Metabolic syndrome, inflammation and oxidative stress as potential risk factors for affective disorders: a twin study

    Ottesen, N. M., Meluken, I., Frikke-Schmidt, Ruth, Plomgaard, Peter Stendahl, Henrik, E. P., Scheike, Thomas, Fernandes, B., Dodd, S., Berk, M., Kessing, Lars Vedel, Miskowiak, K. & Vinberg, Maj, 2019, In: European Neuropsychopharmacology. 29, Supplement 2, p. S706-S707 2 p., P.4.08 .

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors

    Pérez-Alós, L., Armenteros, J. J. A., Madsen, J. R., Hansen, C. B., Jarlhelt, I., Hamm, S. R., Heftdal, L. D., Pries-Heje, M. M., Møller, D. L., Fogh, K., Hasselbalch, R. B., Rosbjerg, A., Brunak, S., Sørensen, E., Larsen, M. A. H., Ostrowski, S. R., Frikke-Schmidt, R., Bayarri-Olmos, R., Hilsted, L. M., Iversen, K. K. & 3 others, Bundgård, Henning, Nielsen, Susanne Dam & Garred, Peter, 2022, In: Nature Communications. 13, 1, 11 p., 1614.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Modifiable cardiovascular risk factors and genetics for targeted prevention of dementia

    Juul Rasmussen, I. & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 28, p. 2526-2543 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Modifications to the Patient Rule-Induction Method that utilize non-additive combinations of genetic and environmental effects to define partitions that predict ischemic heart disease

    Dyson, G., Frikke-Schmidt, Ruth, Nordestgaard, B. G., Tybjærg-Hansen, Anne & Sing, C. F., 2009, In: Genetic Epidemiology. 33, 4, p. 317-24 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Modulation of inflammation by treatment with tocilizumab after out-of-hospital cardiac arrest and associations with clinical status, myocardial- and brain injury

    Meyer, M. A. S., Bjerre, M., Wiberg, S., Grand, J., Obling, L. E. R., Meyer, A. S. P., Josiassen, J., Frydland, M., Thomsen, J. H., Frikke-Schmidt, Ruth, Kjærgaard, Jesper & Hassager, Christian, 2023, In: Resuscitation. 184, 109676.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes

    EADB, E., GR@ACE study group, G. S. G., DEGESCO consortium, D. C., Demgene, D., EADI, E., GERAD, G. & Asian Parkinson’s Disease Genetics consortium, A. P. D. G. C., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 36, 11 p., e2302720120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Mutation in APOA1 predicts increased risk of ischaemic heart disease and mortality without low HDL cholesterol

    Haase, C. L., Frikke-Schmidt, Ruth, Nordestgaard, Børge, Kateifides, A. K., Kardassis, D., Nielsen, L. B., Johnsen, A. H., Grande, P., Zannis, V. I., Tybjaerg-Hansen, A., Johnsen, A. H. & Tybjærg-Hansen, Anne, 2010, In: Amyloid: the Journal of Protein Folding Disorders. 17, p. 129 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  19. Published

    Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels

    Haase, C. L., Frikke-Schmidt, Ruth, Nordestgaard, Børge, Kateifides, A. K., Kardassis, D., Nielsen, L. B., Andersen, C. B., Køber, Lars Valeur, Johnsen, A. H., Grande, P., Zannis, V. I. & Tybjærg-Hansen, Anne, 2011, In: Journal of Internal Medicine. 270, 2, p. 136-46 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2

    Christiansen, M., Hedley, P. L., Theilade, J., Stoevring, B., Leren, T. P., Eschen, O., Sørensen, K. M., Tybjærg-Hansen, Anne, Ousager, L. B., Pedersen, L. N., Frikke-Schmidt, Ruth, Aidt, F. H., Hansen, M. G., Hansen, J., Bloch Thomsen, P. E., Toft, E., Henriksen, F. L., Bundgård, Henning, Jensen, H. K. & Kanters, Jørgen K., 2014, In: BMC Medical Genetics. 15, 11 p., 31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans

    Oldoni, F., van Capelleveen, J. C., Dalila, N., Wolters, J. C., Heeren, J., Sinke, R. J., Hui, D. Y., Dallinga-Thie, G. M., Frikke-Schmidt, Ruth, Hovingh, K. G., van de Sluis, B., Tybjærg-Hansen, Anne & Kuivenhoven, J. A., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 7, p. 1440-1453 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Neutrophil counts and cardiovascular disease

    Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 47, p. 4953-4964 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    New insights into the genetic etiology of Alzheimer's disease and related dementias

    Bellenguez, C., Küçükali, F., Jansen, I. E., Kleineidam, L., Moreno-Grau, S., Amin, N., Naj, A. C., Campos-Martin, R., Grenier-Boley, B., Andrade, V., Holmans, P. A., Boland, A., Damotte, V., van der Lee, S. J., Costa, M. R., Kuulasmaa, T., Yang, Q., de Rojas, I., Bis, J. C., Yaqub, A. & 39 others, Prokic, I., Chapuis, J., Ahmad, S., Giedraitis, V., Aarsland, D., Garcia-Gonzalez, P., Abdelnour, C., Alarcón-Martín, E., Alcolea, D., Alegret, M., Alvarez, I., Álvarez, V., Armstrong, N. J., Tsolaki, A., Antúnez, C., Appollonio, I., Arcaro, M., Archetti, S., Pastor, A. A., Arosio, B., Athanasiu, L., Bailly, H., Banaj, N., Baquero, M., Barral, S., Beiser, A., Nielsen, S. F., Nordestgaard, Børge, Sáez, M. E., Frikke-Schmidt, Ruth, EADB, E., GR@ACE, G., DEGESCO, D., EADI, E., GERAD, G., Demgene, D., FinnGen, F., ADGC, A. & CHARGE, C., 2022, In: Nature Genetics. 54, 4, p. 412-436 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Observational and genetic studies of C-reactive protein levels and risk of Alzheimer's disease

    Frikke-Schmidt, Ruth, Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Thomassen, J. Q., 2022, In: Alzheimer's and Dementia. 18, 12, p. 2734-2735

    Research output: Contribution to journalComment/debateResearchpeer-review

  25. Published

    Observational and genetic studies of short telomeres and Alzheimer’s disease in 67,000 and 152,000 individuals: a Mendelian randomization study

    Scheller Madrid, A., Rasmussen, K. L., Rode, L., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Bojesen, Stig Egil, 2020, In: European Journal of Epidemiology. 35, 2, p. 147-156 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Occupational lifting and risk of hypertension, stratified by use of anti-hypertensives and age - a cross-sectional and prospective cohort study

    Korshøj, M., Hannerz, H., Frikke-Schmidt, Ruth, Marott, J. L., Schnohr, P., Clays, E. & Holtermann, A., 2021, In: BMC Public Health. 21, 1, 721.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Osteoporosis is associated with deteriorating clinical status in adults with cystic fibrosis

    Mathiesen, I. H., Pressler, T., Oturai, P., Katzenstein, T. L., Skov, M., Frikke-Schmidt, Ruth & Hitz, Mette Friberg, 2018, In: International Journal of Endocrinology. 2018, 10 p., 4803974.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Oxygen Targets in Comatose Survivors of Cardiac Arrest

    Schmidt, H., Kjaergaard, J., Hassager, C., Mølstrøm, S., Grand, J., Borregaard, B., Obling, L. E. R., Venø, S., Sarkisian, L., Mamaev, D., Jensen, L. O., Nyholm, B., Høfsten, D. E., Josiassen, J., Thomsen, J. H., Thune, J. J., Lindholm, M. G., Meyer, M. A. S., Winther-Jensen, M., Sørensen, M. & 7 others, Frydland, M., Beske, R. P., Frikke-Schmidt, Ruth, Wiberg, S., Boesgaard, S., Jørgensen, Vibeke Renée Lind & Møller, J. E., 2022, In: New England Journal of Medicine. 387, 16, p. 1467-1476 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Patients with Alzheimer's disease who carry the APOE ε4 allele benefit more from physical exercise

    Jensen, C. S., Simonsen, A. H., Siersma, Volkert Dirk, Beyer, N., Frederiksen, K. S., Gottrup, H., Hoffman, K., Høgh, Peter, Frikke-Schmidt, Ruth, Sobol, N. A., Waldemar, Gunhild, Wermuth, L. & Hasselbalch, Steen, 2019, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, 1, p. 99-106 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Physical Exercise May Increase Plasma Concentration of High-Density Lipoprotein-Cholesterol in Patients With Alzheimer’s Disease

    Jensen, C. S., Musaeus, C. S., Frikke-Schmidt, Ruth, Andersen, B. B., Beyer, N., Gottrup, H., Høgh, Peter, Vestergaard, K., Wermuth, L., Frederiksen, K. S., Waldemar, Gunhild, Hasselbalch, Steen & Simonsen, A. H., 2020, In: Frontiers in Neuroscience. 14, 8 p., 532.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Physical activity in leisure time and at work and risk of dementia: A prospective cohort study of 117,616 individuals

    Juul Rasmussen, I., Rasmussen, Katrine Laura, Thomassen, J. Q., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Atherosclerosis. 360, p. 53-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Plasma Concentrations of Calcium and Risk of Alzheimer Disease—Observational and Genetic Studies

    Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry. 69, 5, p. 525-536 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Plasma Concentrations of Magnesium and Risk of Dementia: A General Population Study of 102 648 Individuals

    Thomassen, J. Q., Tolstrup, J. S., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 6, p. 899-911 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Plasma TSH and cardiovascular disease in the general population: A Mendelian randomization study of 105,224 individuals

    Dalila, N., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2023, In: Atherosclerosis. 376, p. 26-33 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jan 2018, In: Alzheimer's & Dementia. 14, 1, p. 71-80

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Plasma high-density lipoprotein cholesterol and risk of dementia: observational and genetic studies

    Kjeldsen, E. W., Thomassen, J. Q., Juul Rasmussen, I., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Cardiovascular Research. 118, 5, p. 1330-1343 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism

    Karuna, R., Holleboom, A. G., Motazacker, M. M., Kuivenhoven, J. A., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Georgopoulos, S., van Eck, M., van Berkel, T. J. C., von Eckardstein, A. & Rentsch, K. M., 1 Feb 2011, In: Atherosclerosis. 214, 2, p. 448-55 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Plasma levels of apolipoprotein E and risk of dementia in the general population

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Feb 2015, In: Annals of Neurology. 77, 2, p. 301-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Atherosclerosis. 246, p. 63-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Plasma levels of apolipoprotein E, APOE genotype, and all-cause and cause-specific mortality in 105949 individuals from a white general population cohort

    Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 1 Sep 2019, In: European Heart Journal. 40, 33, p. 2813-2824 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Predicting poor neurological outcomes following out-of-hospital cardiac arrest using neuron-specific enolase and neurofilament light chain in patients with and without haemolysis

    Abdi Isse, Y., Frikke-Schmidt, Ruth, Wiberg, Sebastian Christoph, Grand, J., Obling, L. E. R., Meyer, A. S. P., Kjærgaard, Jesper, Hassager, Christian & Meyer, M. A. S., 2023, In: European Heart Journal Open. 3, 4, 7 p., oead078.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

    Obling, L. E. R., Beske, R. P., Meyer, M. A. S., Grand, J., Wiberg, Sebastian Christoph, Nyholm, B., Josiassen, J., Søndergaard, F. T., Mohr, T., Damm-Hejmdal, A., Bjerre, M., Frikke-Schmidt, Ruth, Folke, Fredrik, Møller, J. E., Kjærgaard, Jesper & Hassager, Christian, 2023, In: Intensive Care Medicine. 49, 12, p. 1467-1478 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Previous immunity shapes immune responses to SARS-CoV-2 booster vaccination and Omicron breakthrough infection risk

    Pérez-Alós, L., Hansen, Cecilie Bo, Almagro Armenteros, J. J., Madsen, J. R., Heftdal, Line Dam, Hasselbalch, R. B., Pries-Heje, M. M., Bayarri-Olmos, R., Jarlhelt, I., Hamm, S. R., Møller, D. L., Sørensen, E., Ostrowski, Sisse Rye, Frikke-Schmidt, Ruth, Hilsted, Linda, Bundgård, Henning, Nielsen, Susanne Dam, Iversen, Kasper & Garred, Peter, 2023, In: Nature Communications. 14, 1, 15 p., 5624.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, Varbo, A., CHD Exome+ Consortium, C. E. C., EPIC-CVD Consortium, E. C., ExomeBP Consortium, E. C., Global Lipids Genetics Consortium, G. L. G. C., GoT2D Genes Consortium, G. G. C., EPIC-InterAct Consortium, E. C., INTERVAL Study, I. S., ReproGen Consortium, R. C., T2D-Genes Consortium, T. C., The MAGIC Investigators, T. M. I., Understanding Society Scientific Group, U. S. S. G., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F., 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Rare and low-frequency coding variants alter human adult height

    Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, Locke, A. E., Masca, N. G. D., Ng, M. C. Y., Mudgal, P., Rivas, M. A., Vedantam, S., Mahajan, A., Guo, X., Abecasis, G., Aben, K. K., Allin, K. H., Appel, E. V., Bang, L. E., Benn, Marianne, Bork-Jensen, J., Frikke-Schmidt, Ruth, Grarup, Niels, Hansen, Torben, Hollensted, M., Jensen, G. B., Jørgensen, M. E., Jørgensen, T., Kamstrup, P. R., Linneberg, Allan René, Nielsen, S. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, Tybjærg-Hansen, Anne, drb459, drb459, Pers, Tune H & EPIC-InterAct Consortium, E. C., 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement

    Hegele, R. A., Borén, J., Ginsberg, H. N., Arca, M., Averna, M., Binder, C. J., Calabresi, L., Chapman, M. J., Cuchel, M., von Eckardstein, A., Frikke-Schmidt, R., Gaudet, D., Hovingh, G. K., Kronenberg, F., Lütjohann, D., Parhofer, K. G., Raal, F. J., Ray, K. K., Remaley, A. T., Stock, J. K. & 3 others, Stroes, E. S., Tokgözoğlu, L. & Catapano, A. L., Jan 2020, In: The Lancet Diabetes and Endocrinology. 8, 1, p. 50-67

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

    CHD Exome+ Consortium, C. E. C., CARDIoGRAM Exome Consortium, C. E. C. & Global Lipids Genetics Consortium, G. L. G. C., 11 Mar 2016, In: Science (New York, N.Y.). 351, 6278, p. 1166-71 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Red blood cell parameters in early childhood: a prospective cohort study

    Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Hansen, M. K., Sillesen, A. S., Vøgg, O. R. B., Raja, A. A., Rasmussen, I. J., Kamstrup, P. R., Benn, Marianne, Iversen, Kasper, Bundgård, Henning & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry and Laboratory Medicine. 61, 2, p. 275-284 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Reevaluating the Role of High-Density Lipoprotein Cholesterol: New Perspectives on Cardiovascular Disease and Alzheimer Disease

    Kjeldsen, E. W., Luo, J., Nordestgaard, L. T., Sandau, N. & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry. 69, 12, p. 1329-1332 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Relation between plasma and brain lipids

    Wellington, C. L. & Frikke-Schmidt, Ruth, Jun 2016, In: Current Opinion in Lipidology. 27, 3, p. 225-232 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    Reply to “Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk”

    Luo, J., Thomassen, J. Q., Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Alzheimer's & Dementia. 18, 10, p. 2007-2009 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  52. Published

    S100B and brain derived neurotrophic factor in monozygotic twins with, at risk of and without affective disorders

    Ottesen, N. M., Meluken, I., Frikke-Schmidt, Ruth, Plomgaard, Peter Stendahl, Scheike, Thomas, Kessing, Lars Vedel, Miskowiak, Kamilla & Vinberg, Maj, 2020, In: Journal of Affective Disorders. 274, p. 726-732 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Self-Reported Long COVID and Its Association with the Presence of SARS-CoV-2 Antibodies in a Danish Cohort up to 12 Months after Infection

    Fogh, K., Larsen, T. G., Hansen, Cecilie Bo, Hasselbalch, R. B., Eriksen, A. R. R., Bundgård, Henning, Frikke-Schmidt, Ruth, Hilsted, L. M., Østergaard, L., Johansen, I. S., Hageman, Ida, Garred, Peter & Iversen, Kasper, 2022, In: Microbiology Spectrum. 10, 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Self-reported and genetically predicted coffee consumption and smoking in dementia: A Mendelian randomization study

    Nordestgaard, A. T., Nordestgaard, Børge, Frikke-Schmidt, Ruth, Juul Rasmussen, I. & Bojesen, Stig Egil, 2022, In: Atherosclerosis. 348, p. 36-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Serum cobalamin in children with moderate acute malnutrition in Burkina Faso: Secondary analysis of a randomized trial

    Friis, Henrik, Cichon, B., Fabiansen, C., Iuel-Brockdorff, A., Yaméogo, C. W., Ritz, C., Frikke-Schmidt, Ruth, Briend, A., Michaelsen, Kim F., Christensen, Vibeke Brix, Filteau, S. & Olsen, Mette Frahm, 2022, In: P L o S Medicine (Online). 19, 3, 18 p., e1003943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Serum soluble CD163 predicts risk of type 2 diabetes in the general population

    Møller, H. J., Frikke-Schmidt, Ruth, Moestrup, S., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Feb 2011, In: Clinical Chemistry. 57, 2, p. 291-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Shared Risk Factors between Dementia and Atherosclerotic Cardiovascular Disease

    Nordestgaard, L. T., Christoffersen, M. & Frikke-Schmidt, Ruth, 2022, In: International Journal of Molecular Sciences. 23, 17, 9777.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Short-Lived Antibody-Mediated Saliva Immunity against SARS-CoV-2 after Vaccination

    Madsen, J. R., Holm, B. E., Pérez-Alós, L., Bayarri-Olmos, R., Rosbjerg, A., Fogh, K., Pries-Heje, M. M., Møller, D. L., Hansen, Cecilie Bo, Heftdal, Line Dam, Hasselbalch, R. B., Hamm, S. R., Frikke-Schmidt, Ruth, Hilsted, Linda, Nielsen, Susanne Dam, Iversen, Kasper, Bundgård, Henning & Garred, Peter, 2023, In: Microbiology Spectrum. 11, 2, 11 p., e04947-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Significance of lipids, lipoproteins, and apolipoproteins during the first 14–16 months of life

    Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Rasmussen, I. J., Sillesen, A. S., B. Vøgg, R. O., Raja, A. A., Nordestgaard, Børge, Kamstrup, P. R., Iversen, Kasper, Bundgård, Henning, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 42, p. 4408-4418 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Stroke genetics informs drug discovery and risk prediction across ancestries

    Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y. C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., Parodi, L. & 45 others, Bae, H. J., Chauhan, G., Chong, M. R., Tomppo, L., Akinyemi, R., Roshchupkin, G. V., Habib, N., Jee, Y. H., Thomassen, J. Q., Abedi, V., Cárcel-Márquez, J., Nygaard, M., Leonard, H. L., Yang, C., Yonova-Doing, E., Knol, M. J., Lewis, A. J., Judy, R. L., Ago, T., Amouyel, P., Armstrong, N. D., Bakker, M. K., Bartz, T. M., Bennett, D. A., Bis, J. C., Bordes, C., Børte, S., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth, PRECISEQ Consortium, P. C., FinnGen Consortium, F. C., NINDS Stroke Genetics Network (SiGN), N. S. G. N. (., MEGASTROKE Consortium, M. C., SIREN Consortium, S. C., China Kadoorie Biobank Collaborative Group, C. K. B. C. G., VA Million Veteran Program, V. M. V. P., International Stroke Genetics Consortium (ISGC), I. S. G. C. (., BioBank Japan, B. J., CHARGE Consortium, C. C., GIGASTROKE Consortium, G. C., COMPASS Consortium, C. C., INVENT Consortium, I. C., Dutch Parelsnoer Initiative (PSI) Cerebrovascular Disease Study Group, D. P. I. (. C. D. S. G. & Estonian Biobank, E. B., 2022, In: Nature. 611, 7934, p. 115-123 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Subgroups at high risk for ischaemic heart disease:identification and validation in 67 000 individuals from the general population

    Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dyson, G., Haase, C. L., Benn, Marianne, Nordestgaard, Børge & Sing, C. F., 2015, In: International Journal of Epidemiology. 44, 1, p. 117-128 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Taking action: European Atherosclerosis Society targets the United Nations Sustainable Development Goals 2030 agenda to fight atherosclerotic cardiovascular disease in Europe

    Parini, P., Frikke-Schmidt, Ruth, Tselepis, A. D., Moulin, P., von Eckardstein, A., Binder, C. J., Catapano, A. L., Ray, K. K. & Tokgözoğlu, L., 2021, In: Atherosclerosis. 322, p. 77-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    The ABC-Stroke Risk Score and Effects of Atrial Fibrillation Screening on Stroke Prevention: Results From the Randomized LOOP Study

    Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Frikke-Schmidt, Ruth, Platonov, P. G., Olesen, Morten Steen Salling, Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2024, In: Journal of the American Heart Association. 13, 4, 12 p., e032744.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The ABCG5/8 Cholesterol Transporter and Myocardial Infarction Versus Gallstone Disease

    Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2014, In: Journal of the American College of Cardiology. 63, 20, p. 2121-2128 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    The Age-Specific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled Analysis

    Singh, G. M., Danaei, G., Farzadfar, F., Stevens, G. A., Woodward, M., Wormser, D., Kaptoge, S., Whitlock, G., Qiao, Q., Lewington, S., Di Angelantonio, E., Vander Hoorn, S., Lawes, C. M. M., Ali, M. K., Mozaffarian, D., Ezzati, M., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth, Benn, Marianne & Nordestgaard, Børge, Jul 2013, In: P L o S One. 8, 7, p. 1-10 10 p., e65174.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    The Bipolar Illness Onset study: research protocol for the BIO cohort study

    Kessing, Lars Vedel, Munkholm, K., Faurholt-Jepsen, M., Miskowiak, Kamilla, Nielsen, L. B., Frikke-Schmidt, Ruth, Ekstrøm, Claus Thorn, Winther, Ole, Pedersen, Bente Klarlund, Poulsen, Henrik Enghusen, McIntyre, R. S., Kapczinski, F., Gattaz, W. F., Bardram, J., Frost, M., Mayora, O., Knudsen, Gitte Moos, Phillips, M. & Vinberg, Maj, 2017, In: BMJ Open. 7, 6, 12 p., e015462.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    The Interplay between Adipose Tissue Properties and Levels of NT-proBNP in People with HIV

    Jacobsen, M. H. B., Reimer Jensen, A. M., Knudsen, A. D., Benfield, Thomas, Frikke-Schmidt, Ruth, Nordestgaard, Børge, Afzal, Shoaib, Kofoed, Klaus Fuglsang, Gelpi, M. & Nielsen, Susanne Dam, 2023, In: Journal of Obesity. 2023, 8 p., 6199388.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The current state of apolipoprotein E in dyslipidemia

    Rasmussen, Katrine Laura & Frikke-Schmidt, Ruth, 2024, In: Current Opinion in Lipidology. 35, 2, p. 78-84 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  69. Published

    The extent of B-cell activation and dysfunction preceding lymphoma development in HIV-positive people

    EuroSIDA in EuroCoord, E. I. E., 2018, In: HIV Medicine. 19, 2, p. 90-101 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    The influence of genotype on vascular endothelial growth factor and regulation of myocardial collateral blood flow in patients with acute and chronic coronary heart disease

    Ripa, R. S., Jorgensen, E., Baldazzi, F., Frikke-Schmidt, Ruth, Wang, Y., Tybjærg-Hansen, Anne & Kastrup, J., 2009, In: Scandinavian Journal of Clinical & Laboratory Investigation. 69, 6, p. 722-728 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles

    Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Triglycerides as a Shared Risk Factor between Dementia and Atherosclerotic Cardiovascular Disease: A Study of 125 727 Individuals

    Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 1, p. 245-255 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Type-2 diabetes and risk of dementia: observational and Mendelian randomisation studies in 1 million individuals

    Thomassen, J. Q., Tolstrup, J. S., Benn, Marianne & Frikke-Schmidt, Ruth, 2020, In: Epidemiology and Psychiatric Sciences. 29, 11 p., e118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies

    Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 2018, In: European Heart Journal. 39, 14, p. 1181-1190 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations

    Motazedi, E., Cheng, W., Thomassen, J. Q., Frei, O., Rongve, A., Athanasiu, L., Bahrami, S., Shadrin, A., Ulstein, I., Stordal, E., Brækhus, A., Saltvedt, I., Sando, S. B., O'Connell, K. S., Hindley, G., Van Der Meer, D., Bergh, S., Nordestgaard, B. G., Tybjærg-Hansen, A., Brthen, G. & 10 others, Pihlstrm, L., Djurovic, S., Frikke-Schmidt, Ruth, Fladby, T., Aarsland, D., Selbæk, G., Seibert, T. M., Dale, A. M., Fan, C. C. & Andreassen, O. A., 2022, In: Journal of Alzheimer's Disease. 88, 4, p. 1533-1544

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer

    Kobberø Lauridsen, B., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2017, In: International Journal of Epidemiology. 46, 6, p. 1777-1785

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study

    Lusk, C. M., Dyson, G., Clark, A. G., Ballantyne, C. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Boerwinkle, E. & Sing, C. F., Sep 2014, In: Human Genetics. 133, 9, p. 1105-1116 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Validation of a novel automated system, Fluispotter®, for serial sampling of dried blood spots

    Krogh, Jesper, Plomgaard, Peter Stendahl, Frikke-Schmidt, Ruth, Velschow, S., Johannesen, Jesper, Hilsted, L. M., Schrøder, M. & Feldt-Rasmussen, Ulla, 2023, In: Endocrine Connections. 12, 7, 9 p., e230087.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Vegetarian or vegan diets and blood lipids: a meta-analysis of randomized trials

    Koch, C. A., Kjeldsen, E. W. & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 28, p. 2609–2622 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Visible Age-Related Signs and Risk of Ischemic Heart Disease in the General Population: A Prospective Cohort Study

    Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 4 Mar 2014, In: Circulation Research. 129, 9, p. 990-998 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Waning humoral and cellular immunity after COVID-19 vaccination in patients with psoriasis treated with methotrexate and biologics: A cohort study

    Kvist-Hansen, A., Pérez-Alós, L., Al-Sofi, R. F., Heftdal, L. D., Hamm, S. R., Møller, D. L., Pries-Heje, M. M., Fogh, K., Bo Hansen, C., Bo Hasselbalch, R., Madsen, J. R., Armenteros, J. J. A., Frikke-Schmidt, R., Hilsted, L., Sørensen, E., Ostrowski, S. R., Bundgaard, H., Nielsen, S. D., Iversen, K., Zachariae, C. & 2 others, Garred, Peter & Skov, Lone, 2023, In: British Journal of Dermatology. 188, 5, p. 661-669 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

    Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

    Zhou, B., Carrillo-Larco, R. M., Danaei, G., Riley, L. M., Paciorek, C. J., Stevens, G. A., Gregg, E. W., Bennett, J. E., Solomon, B., Singleton, R. K., Sophiea, M. K., Iurilli, M. LC., Lhoste, V. PF., Cowan, M. J., Savin, S., Woodward, M., Balanova, Y., Cifkova, R., Damasceno, A., Elliott, P. & 31 others, Farzadfar, F., Afzal, Shoaib, Allin, K., Andersen, L. B., Bjerregaard, P., Bojesen, Stig Egil, Christensen, K., Dantoft, T. M., Eliasen, M., Eriksen, L., Frikke-Schmidt, Ruth, Giwercman, A., Halkjær, J., Jørgensen, T., Kristensen, P. L., Lind, L., Linneberg, Allan René, Mårild, S. B., Møllehave, Line Tang, Nguyen, Q. V., Nordestgaard, Børge, Overvad, K., Schnohr, P., Sobngwi, E., Sørensen, Thorkild I.A., Tjønneland, Anne, Toft, Ulla Marie Nørgaard, Tolstrup, J. S., Wang, Y. W., Yang, Y. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2021, In: The Lancet. 398, 10304, p. 957-980 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Xanthelasmas Predict Risk of Ischemic Heart Disease, Myocardial Infarction, and Overall Death in the General Population

    Christoffersen, M., Frikke-Schmidt, Ruth, Schnohr, P., Nordestgaard, Børge, Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 33 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

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