Anne-Marie Axø Gerdes
Clinical Professor
- 2023
- Published
Associations of height, body mass index, and weight gain with breast cancer risk in carriers of a pathogenic variant in BRCA1 or BRCA2: the BRCA1 and BRCA2 Cohort Consortium
EMBRACE Collaborators, E. C., Dec 2023, In: Breast Cancer Research. 25, 1, 13 p., 72.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TINF2 is a major susceptibility gene in Danish patients with multiple primary melanoma
Jensen, M. R., Jelsig, A. M., Gerdes, Anne-Marie Axø, Hølmich, Lisbet Rosenkrantz, mzt627, mzt627, Lorentzen, H. F., Hansen, M. H., Bak, M., Johansson, P. A., Hayward, N. K., Hansen, Thomas van Overeem & Wadt, Karin Anna Wallentin, 2023, In: Human Genetics and Genomics Advances. 4, 4, 12 p., 100225.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combinatorial batching of DNA for ultralow-cost detection of pathogenic variants
Stoltze, U. K., Hagen, C. M., Hansen, Thomas van Overeem, Byrjalsen, A., Gerdes, Anne-Marie Axø, Yakimov, V., Rasmussen, Simon, Bækvad-Hansen, M., Hougaard, D. M., Schmiegelow, Kjeld, Hjalgrim, Henrik, Wadt, Karin Anna Wallentin & Bybjerg-Grauholm, J., 2023, In: Genome Medicine. 15, 12 p., 17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ethics in pre-ART genetics: a missed X-linked Menkes disease case
Gerdes, Anne-Marie Axø, Møller, L. B. & Horn, N., 2023, In: Journal of Assisted Reproduction and Genetics. 40, 4, p. 811-816 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic predisposition & evolutionary traces of pediatric cancer risk: a prospective 5-year population-based genome sequencing study of children with CNS tumors
Stoltze, U. K., Foss-Skiftesvik, J., Hansen, Thomas van Overeem, Byrjalsen, A., Sehested, A., Scheie, David, Mikkelsen, T. S., Rasmussen, Simon, Bak, M., Okkels, H., Callesen, M. T., Skjøth-Rasmussen, J., Gerdes, Anne-Marie Axø, Schmiegelow, Kjeld, Mathiasen, R. & Wadt, Karin Anna Wallentin, 2023, In: Neuro-Oncology. 25, 4, p. 761-773Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-BRCA1/BRCA2 high-risk familial breast cancers are not associated with a high prevalence of BRCAness
Andersen, L. V. B., Larsen, M. J., Davies, H., Degasperi, A., Nielsen, H. R., Jensen, L. A., Kroeldrup, L., Gerdes, Anne-Marie Axø, Lænkholm, Anne-Vibeke, Kruse, T. A., Nik-Zainal, S. & Thomassen, M., 2023, In: Breast Cancer Research. 25, 1, 10 p., 69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants
HEBON Investigators, H. I., 2023, In: npj Breast Cancer. 9, 1, 15 p., 37.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of a single SMARCA4 exon deletion on RNA splicing: Implications for variant classification
Byrjalsen, A., Stoltze, U., Mehrjouy, M., Frederiksen, J. H., Bak, M., Birkedal, U., Hasle, H., Gerdes, Anne-Marie Axø, Schmiegelow, Kjeld, Wadt, Karin Anna Wallentin & Hansen, Thomas van Overeem, 2023, In: Molecular Genetics and Genomic Medicine. 11, 10, 7 p., e2232.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Update of penetrance estimates in Birt-Hogg-Dubé syndrome
Bruinsma, F. J., Dowty, J. G., Win, A. K., Goddard, L. C., Agrawal, P., Attina', D., Bissada, N., De Luise, M., Eisen, D. B., Furuya, M., Gasparre, G., Genuardi, M., Gerdes, A. M., Hansen, T. V. O., Houweling, A. C., Johannesma, P. C., Lencastre, A., Lim, D., Lindor, N. M., Luzzi, V. & 20 others, , 2023, In: Journal of Medical Genetics. 60, 4, p. 317-326 10 p.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
Cancer Prevention with Resistant Starch in Lynch Syndrome Patients in the CAPP2-Randomized Placebo Controlled Trial: Planned 10-Year Follow-up
the CAPP2 Investigators, T. C. I., 2022, In: Cancer Prevention Research. 15, 9, p. 623-634Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical implications of genetic testing in familial intermediate and late-onset colorectal cancer
Djursby, M., Hansen, Thomas van Overeem, Wadt, Karin Anna Wallentin, Madsen, M. B., Berchtold, L. A., Lautrup, C. K., Markholt, S., Jensen, U. B., Krogh, L. N., Lundsgaard, M., Gerdes, Anne-Marie Axø, Nilbert, Mef Christina & Therkildsen, C., 2022, In: Human Genetics. 141, p. 1925–1933Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
The European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC), T. E. H. T. G. (. A. T. I. M. R. C. (., 2022, In: Hereditary Cancer in Clinical Practice. 20, 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Etik og jura
Ousager, L. B., Gerdes, Anne-Marie Axø & Kristensen, K., 2022, Medicinsk genetik. FADL's Forlag, p. 477-500Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
ENIGMA Consortium, E. C. & CIMBA Consortium, C. C., 2022, In: Genetics in Medicine. 24, 1, p. 119-129 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole genome sequencing identifies rare genetic variants in familial pancreatic cancer patients
Tan, M., Brusgaard, K., Gerdes, Anne-Marie Axø, Larsen, M. J., Mortensen, M. B., Detlefsen, S., de Muckadell, O. B. S. & Joergensen, M. T., 2022, In: Annals of Human Genetics. 86, 4, p. 195-206 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Birth cohort-specific trends of sun-related behaviors among individuals from an international consortium of melanoma-prone families
Lacson, J. C. A., Zamani, S. A., Froes, L. A. R., Mitra, N., Qian, L., Doyle, S. H., Azizi, E., Balestrini, C., Bishop, D. T., Bruno, W., Carlos-ortega, B., Cuellar, F., Cust, A. E., Elder, D. E., Gerdes, A., Ghiorzo, P., Grazziotin, T. C., Gruis, N. A., Hansson, J., Hočevar, M. & 18 others, , 1 Dec 2021, In: BMC Public Health. 21, 1, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort profile and heritability assessment of familial pancreatic cancer: a nation-wide study
Tan, M., Brusgaard, K., Gerdes, Anne-Marie Axø, Mortensen, M. B., Detlefsen, S., Schaffalitzky De Muckadell, O. B. & Joergensen, M. T., 3 Aug 2021, In: Scandinavian Journal of Gastroenterology. 56, 8, p. 965-971 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumour-infiltrating CD4-, CD8- and FOXP3-positive immune cells as predictive markers of mortality in BRCA1- and BRCA2-associated breast cancer
Jørgensen, N., Hviid, Thomas Vauvert F., Nielsen, L. B., Sønderstrup, I. M. H., Eriksen, J. O., Ejlertsen, Bent Laursen, Gerdes, Anne-Marie Axø, Kruse, T. A., Thomassen, M., Jensen, M. & Lænkholm, Anne-Vibeke, Aug 2021, In: British Journal of Cancer. 125, p. 1388–1398Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study
Epidemiological Study of Familial Breast Cancer, Gene Etude Prospective Sein Ovaire Sein, Hereditary Breast and Ovarian Cancer Research Group Netherlands, and International BRCA1/2 Carrier Cohort Study, E. S. O. F. B. C. G. E. P. S. O. S. H. B. A. O. C. R. G. N. A. I. B. C. C. S., Jul 2021, In: American Journal of Obstetrics and Gynecology. 225, 1, p. 51.e1-51.e17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study
The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct to consumer genetic testing in Denmark—public knowledge, use, and attitudes
Gerdes, Anne-Marie Axø, Nicolaisen, L., Husum, E., Andersen, J. B., Gantzhorn, M. D., Roos, L. & Diness, Birgitte Rode, May 2021, In: European Journal of Human Genetics. 29, 5, p. 851-860 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetisk screening af adopterede raske individer
Wriedt, T. R., Gerdes, Anne-Marie Axø, Roos, L. K., Hammer-Hansen, S., Christensen, M. B. & Diness, Birgitte Rode, 29 Mar 2021, In: Ugeskrift for Laeger. 183, 13, 7 p., V11200810.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetisk screening af kommende forældre
Smed, V. M., Petersen, Olav Bennike Bjørn, Gerdes, Anne-Marie Axø, Diness, Birgitte Rode & Roos, L. S., 29 Mar 2021, In: Ugeskrift for Laeger. 183, 13, 9 p., V12200933.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selection criteria for assembling a pediatric cancer predisposition syndrome gene panel
Byrjalsen, A., Diets, I. J., Bakhuizen, J., Hansen, Thomas van Overeem, Schmiegelow, Kjeld, Gerdes, Anne-Marie Axø, Stoltze, U., Kuiper, R. P., Merks, J. H. M., Wadt, Karin Anna Wallentin & Jongmans, M., 2021, In: Familial Cancer. 20, 4, p. 279-287 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant
GEMO Study Collaborators, G. S. C., EMBRACE Collaborators, E. C., OCGN Investigators, O. I., HEBON Investigators, H. I. & kConFab Investigators, K. I., 2021, In: Genetics in Medicine. 23, 9, p. 1726-1737Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole genome sequencing identifies rare germline variants enriched in cancer related genes in firstdegree relatives of familial pancreatic cancer patients
Tan, M., Brusgaard, K., Gerdes, Anne-Marie Axø, Mortensen, M. B., Detlefsen, S., Schaffalitzky de Muckadell, O. B. & Joergensen, M. T., 2021, In: Clinical Genetics. 100, 5, p. 551-562 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
Olafsdottir, E. J., Borg, A., Jensen, M., Gerdes, Anne-Marie Axø, Johansson, A. L. V., Barkardottir, R. B., Johannsson, O. T., Ejlertsen, Bent Laursen, Sønderstrup, I. M. H., Hovig, E., Lænkholm, Anne-Vibeke, Hansen, T. V. O., Olafsdottir, G. H., Rossing, M., Jonasson, J. G., Sigurdsson, S., Loman, N., Nilsson, M. P., Narod, S. A. & Tryggvadottir, L., Nov 2020, In: British Journal of Cancer. 123, 11, p. 1608-1615 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants
Barnes, D. R., Rookus, M. A., Mcguffog, L., Leslie, G., Mooij, T. M., Dennis, J., Mavaddat, N., Adlard, J., Ahmed, M., Aittomäki, K., Andrieu, N., Andrulis, I. L., Arnold, N., Arun, B. K., Azzollini, J., Balmaña, J., Barkardottir, R. B., Barrowdale, D., Benitez, J., Berthet, P. & 31 others, , 1 Oct 2020, In: Genetics in Medicine. 22, 10, p. 1653-1666 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness
Patel, V. L., Busch, E. L., Friebel, T. M., Cronin, A., Leslie, G., McGuffog, L., Adlard, J., Agata, S., Agnarsson, B. A., Ahmed, M., Aittomäki, K., Alducci, E., Andrulis, I. L., Arason, A., Arnold, N., Artioli, G., Arver, B., Auber, B., Azzollini, J., Balmaña, J. & 243 others, , 1 Feb 2020, In: Cancer Research. 80, 3, p. 624-638 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium
Li, H., Terry, M. B., Antoniou, A. C., Phillips, K-A., Kast, K., Mooij, T. M., Engel, C., Noguès, C., Stoppa-Lyonnet, D., Lasset, C., Berthet, P., Mari, V., Caron, O., Barrowdale, D., Frost, D., Brewer, C., Evans, D. G., Izatt, L., Side, L., Walker, L. & 31 others, , Feb 2020, In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 29, 2, p. 368-378 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers
Mavaddat, N., Antoniou, A. C., Mooij, T. M., Hooning, M. J., Heemskerk-Gerritsen, B. A., Noguès, C., Gauthier-Villars, M., Caron, O., Gesta, P., Pujol, P., Lortholary, A., Barrowdale, D., Frost, D., Evans, D. G., Izatt, L., Adlard, J., Eeles, R., Brewer, C., Tischkowitz, M., Henderson, A. & 31 others, , 16 Jan 2020, In: Breast Cancer Research. 22, 1, 11 p., 8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A rare missense variant in APC interrupts splicing and causes AFAP in two Danish families
Djursby, M., Wadt, Karin Anna Wallentin, Frederiksen, J. H., Madsen, M. B., Berchtold, L. A., Hasselby, Jane Preuss, Willemoe, G. L., Hansen, T. V. O. & Gerdes, Anne-Marie Axø, 2020, In: Hereditary Cancer in Clinical Practice. 18, 1, 8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial
Burn, J., Sheth, H., Elliott, F., Reed, L., Macrae, F., Mecklin, J. P., Möslein, G., McRonald, F. E., Bertario, L., Evans, D. G., Gerdes, A. M., Ho, J. W. C., Lindblom, A., Morrison, P. J., Rashbass, J., Ramesar, R., Seppälä, T., Thomas, H. J. W., Pylvänäinen, K., Borthwick, G. M. & 15 others, , 2020, In: The Lancet. 395, 10240, p. 1855-1863 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the Cancer Spectrum in Men with Germline BRCA1 and BRCA2 Pathogenic Variants: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)
Silvestri, V., Leslie, G., Barnes, D. R., Agnarsson, B. A., Aittomäki, K., Alducci, E., Andrulis, I. L., Barkardottir, R. B., Barroso, A., Barrowdale, D., Benitez, J., Bonanni, B., Borg, A., Buys, S. S., Caldés, T., Caligo, M. A., Capalbo, C., Campbell, I., Chung, W. K., Claes, K. B. M. & 103 others, , 2020, In: JAMA Oncology. 6, 8, p. 1218-1230Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nationwide germline whole genome sequencing of 198 consecutive pediatric cancer patients reveals a high frequency of cancer prone syndromes
Byrjalsen, A., Hansen, T. V. O., Stoltze, U. K., Mehrjouy, M. M., Barnkob, N. M., Hjalgrim, L. L., Mathiasen, R., Lautrup, C. K., Gregersen, P. A., Hasle, H., Wehner, P. S., Tuckuviene, R., Sackett, P. W., Laspiur, A. O., Rossing, M., Marvig, R. L., Tommerup, N., Olsen, T. E., Scheie, D., Gupta, R. & 3 others, , 2020, In: PLOS Genetics. 16, 12, e1009231.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New Pathogenic Germline Variants in Very Early Onset and Familial Colorectal Cancer Patients
Djursby, M., Madsen, M. B., Frederiksen, J. H., Berchtold, L. A., Therkildsen, C., Willemoe, G. L., Hasselby, Jane Preuss, Wikman, F., Okkels, H., Skytte, A. B., Nilbert, Mef Christina, Wadt, Karin Anna Wallentin, Gerdes, Anne-Marie Axø & van Overeem Hansen, T., 2020, In: Frontiers in Genetics. 11, 566266.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Estimating CDKN2A mutation carrier probability among global familial melanoma cases using GenoMELPREDICT
Taylor, N. J., Mitra, N., Qian, L., Avril, M. F., Bishop, D. T., Bressac-de Paillerets, B., Bruno, W., Calista, D., Cuellar, F., Cust, A. E., Demenais, F., Elder, D. E., Gerdes, A. M., Ghiorzo, P., Goldstein, A. M., Grazziotin, T. C., Gruis, N. A., Hansson, J., Harland, M., Hayward, N. K. & 23 others, , Aug 2019, In: Journal of the American Academy of Dermatology. 81, 2, p. 386-394Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subtypes in BRCA-mutated breast cancer
Sønderstrup, I. M. H., Jensen, M. R., Ejlertsen, Bent Laursen, Eriksen, J. O., Gerdes, Anne-Marie Axø, Kruse, T. A., Larsen, M. J., Thomassen, M. & Lænkholm, Anne-Vibeke, Feb 2019, In: Human Pathology. 84, p. 192-201 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A healthy individual with a homozygous PTCH2 frameshift variant: Are variants of PTCH2 associated with nevoid basal cell carcinoma syndrome?
Altaraihi, M., Wadt, Karin Anna Wallentin, Ek, J., Gerdes, Anne-Marie Axø & Østergaard, Elsebet, 2019, In: Human Genome Variation. 6, 1, 10.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new family with a homozygous nonsense variant in NTHL1 further delineated the clinical phenotype of NTHL1-associated polyposis
Altaraihi, M., Gerdes, Anne-Marie Axø & Wadt, Karin Anna Wallentin, 2019, In: Human Genome Variation. 6, 3 p., 46.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome
Abildgaard, A. B., Stein, Amelie, Nielsen, S. V., Schultz-Knudsen, Katrine, Papaleo, E., Shrikhande, A., Hoffmann, Eva, Bernstein, I., Gerdes, Anne-Marie Axø, Takahashi, M., Ishioka, C., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2019, In: eLife. 8, 28 p., e49138 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of tumor-infiltrating lymphocytes and association with prognosis in BRCA-mutated breast cancer
Sønderstrup, I. M. H., Jensen, M. B., Ejlertsen, Bent Laursen, Eriksen, J. O., Gerdes, Anne-Marie Axø, Kruse, T. A., Larsen, M. J., Thomassen, M. & Lænkholm, Anne-Vibeke, 2019, In: Acta Oncologica. 58, 3, p. 363-370 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the hereditary background of renal cancer in Denmark
Christensen, M. B., Wadt, Karin Anna Wallentin, Jensen, U. B., Lautrup, C. K., Bojesen, A., Krogh, L. N., Overeem Hansen, T. V. & Gerdes, Anne-Marie Axø, 2019, In: PLoS ONE. 14, 4, 16 p., e0215725.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic counselling and testing of susceptibility genes for therapeutic decision-making in breast cancer - an European consensus statement and expert recommendations
Singer, C. F., Balmaña, J., Bürki, N., Delaloge, S., Filieri, M. E., Gerdes, Anne-Marie Axø, Grindedal, E. M., Han, S., Johansson, O., Kaufman, B., Krajc, M., Loman, N., Olah, E., Paluch-Shimon, S., Plavetic, N. D., Pohlodek, K., Rhiem, K., Teixeira, M. & Evans, D. G., 2019, In: European Journal of Cancer. 106, p. 54-60 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomisk medicin til præimplantations-, præ- og postnatal diagnostik
Gerdes, Anne-Marie Axø, Risom, L., Kjærgaard, S. & Østergaard, Elsebet, 2019, In: Ugeskrift for Laeger. 181, 7A, 5 p., V11180756.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification
Parsons, M. T., Tudini, E., Li, H., Hahnen, E., Wappenschmidt, B., Feliubadaló, L., Aalfs, C. M., Agata, S., Aittomäki, K., Alducci, E., Alonso-Cerezo, M. C., Arnold, N., Auber, B., Austin, R., Azzollini, J., Balmaña, J., Barbieri, E., Bartram, C. R., Blanco, A., Blümcke, B. & 31 others, , 2019, In: Human Mutation. 40, 9, p. 1557-1578 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toward mechanistic models for genotype-phenotype correlations in phenylketonuria using protein stability calculations
Scheller, R., Stein, Amelie, Nielsen, S. V., Marin, F. I., Gerdes, Anne-Marie Axø, Di Marco, M., Papaleo, E., Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2019, In: Human Mutation. 40, 4, p. 444-457Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Clinical and molecular characterization of BRCA-associated breast cancer: results from the DBCG
Soenderstrup, I. M. H., Lænkholm, Anne-Vibeke, Jensen, M. B., Eriksen, J. O., Gerdes, Anne-Marie Axø, Hansen, T. V. O., Kruse, T. A., Larsen, M. J., Pedersen, I. S., Rossing, M., Thomassen, M. & Ejlertsen, B., 2018, In: Acta Oncologica. 57, 1, p. 95-101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark
Stoltze, U., Skytte, A., Roed, H., Hasle, H., Ejlertsen, B., Overeem Hansen, T. V., Schmiegelow, Kjeld, Gerdes, Anne-Marie Axø & Wadt, K., 2018, In: PLoS ONE. 13, 1, 11 p., e0190050.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
En familie med nedarvet DICER1-mutation
Altaraihi, M., Pedersen, J., Rossing, M., Gerdes, Anne-Marie Axø & Wadt, K., 2018, In: Ugeskrift for Laeger. 180, 25, 2 p., V01180063.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Is DBCG abreast of new developments?
Offersen, B. V., Ejlertsen, B., Balslev, E., Flyger, H., Gerdes, Anne-Marie Axø, Hansen, M. K., Hølmich, Lisbet Rosenkrantz, Jensen, M., Kristensen, B., Lænkholm, Anne-Vibeke, Mouridsen, H. T., Nielsen, M. H., Overgaard, J., Tuxen, M., Vejborg, I. & Christiansen, P., 2018, In: Acta Oncologica. 57, 1, p. 1-2 2 p.Research output: Contribution to journal › Editorial › Research
- Published
Kræftdisponerende mutationer er hyppige hos børn og unge med kræft
Stoltze, U. K., Byrjalsen, A., Hjalgrim, L. L., Wahlberg, A., Gupta, R., Gerdes, Anne-Marie Axø, Wadt, K. & Schmiegelow, Kjeld, 2018, In: Ugeskrift for Laeger. 180, 17, 6 p., V07170566.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations
EMBRACE, E., 2018, In: Human Mutation. 39, 5, p. 593-620 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pediatric cancer families' participation in whole-genome sequencing research in Denmark: Parent perspectives
Byrjalsen, A., Stoltze, U., Wadt, K., Hjalgrim, L. L., Gerdes, Anne-Marie Axø, Schmiegelow, Kjeld & Wahlberg, Ayo, 2018, In: European Journal of Cancer Care. 27, 6, p. 1-11 11 p., e12877.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant: breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium
Moghadasi, S., Meeks, H. D., Vreeswijk, M. P., Janssen, L. A., Borg, Å., Ehrencrona, H., Paulsson-Karlsson, Y., Wappenschmidt, B., Engel, C., Gehrig, A., Arnold, N., Hansen, T. V. O., Thomassen, M., Jensen, U. B., Kruse, T. A., Ejlertsen, B., Gerdes, A-M., Pedersen, I. S., Caputo, S. M., Couch, F. & 20 others, , 2018, In: Journal of Medical Genetics. 55, 1, p. 15-20Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Blocking protein quality control to counter hereditary cancers
Kampmeyer, Caroline, Nielsen, S. V., Bjørnkjær, Lene, Stein, Amelie, Gerdes, Anne-Marie Axø, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, Dec 2017, In: Genes, Chromosomes & Cancer. 56, 12, p. 823-831 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Germline Variation at CDKN2A and Associations with Nevus Phenotypes among Members of Melanoma Families
Taylor, N. J., Mitra, N., Goldstein, A. M., Tucker, M. A., Avril, M-F., Azizi, E., Bergman, W., Bishop, D. T., Bressac-de Paillerets, B., Bruno, W., Calista, D., Cannon-Albright, L. A., Cuellar, F., Cust, A. E., Demenais, F., Elder, D. E., Gerdes, A-M., Ghiorzo, P., Grazziotin, T. C., Hansson, J. & 25 others, , Dec 2017, In: The Journal of Investigative Dermatology. 137, 12, p. 2606-2612 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers
Kuchenbaecker, K. B., Hopper, J. L., Barnes, D. R., Phillips, K-A., Mooij, T. M., Roos-Blom, M-J., Jervis, S., van Leeuwen, F. E., Milne, R. L., Andrieu, N., Goldgar, D. E., Terry, M. B., Rookus, M. A., Easton, D. F., Antoniou, A. C., McGuffog, L., Evans, D. G., Barrowdale, D., Frost, D., Adlard, J. & 31 others, , 20 Jun 2017, In: J A M A: The Journal of the American Medical Association. 317, 23, p. 2402-2416 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Classification of the spliceogenic BRAC1 c.4096+3A>G variant as likely benign based on cosegregation data and identification of a healthy homozygous carrier
Byrjalsen, A., Steffensen, A. Y., Hansen, T. V. O., Wadt, K. & Gerdes, Anne-Marie Axø, Jun 2017, In: Clinical Case Reports. 5, 6, p. 876-879 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
Phelan, C. M., Kuchenbaecker, K. B., Tyrer, J. P., Kar, S. P., Lawrenson, K., Winham, S. J., Dennis, J., Pirie, A., Riggan, M. J., Chornokur, G., Earp, M. A., Lyra, P. C., Lee, J. M., Coetzee, S., Beesley, J., McGuffog, L., Soucy, P., Dicks, E., Lee, A., Barrowdale, D. & 31 others, , May 2017, In: Nature Genetics. 49, 5, p. 680-691Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3
Hamdi, Y., Soucy, P., Kuchenbaeker, K. B., Pastinen, T., Droit, A., Lemaçon, A., Adlard, J., Aittomäki, K., Andrulis, I. L., Arason, A., Arnold, N., Azzollini, J., Arun, B. K., Bane, A., Barjhoux, L., Barrowdale, D., Benitez, J., Berthet, P., Blok, M. J., Bobolis, K. A. & 34 others, , Jan 2017, In: Breast Cancer Research and Treatment. 161, 1, p. 117-134 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fordele og ulemper ved forbrugergenetik
Christiansen, C. W. & Gerdes, Anne-Marie Axø, 2017, In: Ugeskrift for Laeger. 179, 11, 4 p., V12160896.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation
Rossing, M., Albrechtsen, Anders, Skytte, A., Jensen, U. B., Ousager, L. B., Gerdes, Anne-Marie Axø, Nielsen, Finn Cilius & Hansen, T. V. O., 2017, In: Journal of Human Genetics. 62, p. 151-157 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
Milne, R. L., Kuchenbaecker, K. B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M. K., McGuffog, L., Wang, Q., Aalfs, C. M., ABCTB Investigators, Adams, M., Adlard, J. & 27 others, , 2017, In: Nature Genetics. 49, 12, p. 1767-1778Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Current perspectives on recommendations for BRCA genetic testing in ovarian cancer patients
Vergote, I., Banerjee, S., Gerdes, Anne-Marie Axø, van Asperen, C. J., Marth, C., Vaz, F., Ray-Coquard, I., Stoppa-Lyonnet, D., Gonzalez-Martin, A., Sehouli, J. & Colombo, N., Dec 2016, In: European journal of cancer (Oxford, England : 1990). 69, p. 127-134 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JP-HHT phenotype in Danish patients with SMAD4 mutations
Jelsig, A. M., Tørring, P. M., Kjeldsen, A. D., Qvist, N., Bojesen, A., Jensen, U. B., Andersen, M. K., Gerdes, Anne-Marie Axø, Brusgaard, K. & Ousager, L. B., Jul 2016, In: Clinical Genetics. 90, 1, p. 55-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An international survey of surveillance schemes for unaffected BRCA1 and BRCA2 mutation carriers
Madorsky-Feldman, D., Sklair-Levy, M., Perri, T., Laitman, Y., Paluch-Shimon, S., Schmutzler, R., Rhiem, K., Lester, J., Karlan, B. Y., Singer, C. F., Van Maerken, T., Claes, K., Brunet, J., Izquierdo, A., Teulé, A., Lee, J. W., Kim, S-W., Arun, B., Jakubowska, A., Lubinski, J. & 18 others, , Jun 2016, In: Breast Cancer Research and Treatment. 157, 2, p. 319-327 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disease pattern in Danish patients with Peutz-Jeghers syndrome
Jelsig, A. M., Qvist, N., Sunde, L., Brusgaard, K., Hansen, T. V. O., Wikman, F. P., Nielsen, C. B., Nielsen, I. K., Gerdes, Anne-Marie Axø, Bojesen, A. & Ousager, L. B., May 2016, In: International Journal of Colorectal Disease. 31, 5, p. 997-1004 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
Hollestelle, A., van der Baan, F. H., Berchuck, A., Johnatty, S. E., Aben, K. K., Agnarsson, B. A., Aittomäki, K., Alducci, E., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Antoniou, A. C., Apicella, C., Arndt, V., Arnold, N., Arun, B. K., Arver, B., Ashworth, A., Baglietto, L., Balleine, R. & 31 others, , May 2016, In: Gynecologic Oncology. 141, 2, p. 386–401Research output: Contribution to journal › Review › Research › peer-review
- Published
Phenotypic and Histopathological Tumor Characteristics According to CDKN2A Mutation Status among Affected Members of Melanoma Families
Taylor, N. J., Handorf, E. A., Mitra, N., Avril, M-F., Azizi, E., Bergman, W., Bianchi-Scarrà, G., Bishop, D. T., Bressac-de Paillerets, B., Calista, D., Cannon-Albright, L. A., Cuellar, F., Cust, A. E., Demenais, F., Elder, D. E., Friedman, E., Gerdes, A-M., Ghiorzo, P., Goldstein, A. M., Grazziotin, T. C. & 27 others, , May 2016, In: Journal of Investigative Dermatology. 136, 5, p. 1066-1069 4 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
Silvestri, V., Barrowdale, D., Mulligan, A. M., Neuhausen, S. L., Fox, S., Karlan, B. Y., Mitchell, G., James, P., Thull, D. L., Zorn, K. K., Carter, N. J., Nathanson, K. L., Domchek, S. M., Rebbeck, T. R., Ramus, S. J., Nussbaum, R. L., Olopade, O. I., Rantala, J., Yoon, S-Y., Caligo, M. A. & 31 others, , 9 Feb 2016, In: Breast Cancer Research (Online). 18, 13 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Germline TERT promoter mutations are rare in familial melanoma
Harland, M., Petljak, M., Robles-Espinoza, C. D., Ding, Z., Gruis, N. A., van Doorn, R., Pooley, K. A., Dunning, A. M., Aoude, L. G., Wadt, K. A. W., Gerdes, Anne-Marie Axø, Brown, K. M., Hayward, N. K., Newton-Bishop, J. A., Adams, D. J. & Bishop, D. T., Jan 2016, In: Familial Cancer. 15, 1, p. 139-44 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer
Jønson, L., Ahlborn, L. B., Steffensen, A. Y., Djursby, M., Ejlertsen, B., Timshel, S., Nielsen, Finn Cilius, Gerdes, Anne-Marie Axø & Hansen, T. V. O., Jan 2016, In: Breast Cancer Research and Treatment. 155, 2, p. 215-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers
Meeks, H. D., Song, H., Michailidou, K., Bolla, M. K., Dennis, J., Wang, Q., Barrowdale, D., Frost, D., McGuffog, L., Ellis, S., Feng, B., Buys, S. S., Hopper, J. L., Southey, M. C., Tesoriero, A., James, P. A., Bruinsma, F., Campbell, I. G., Broeks, A., Schmidt, M. K. & 31 others, , 2016, In: JNCI - Journal of the National Cancer Institute. 108, 2, 10 p., djv315.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4
Johansson, P., Aoude, L. G., Wadt, K., Glasson, W. J., Warrier, S. K., Hewitt, A. W., Kiilgaard, Jens Folke, Heegaard, Steffen, Isaacs, T., Franchina, M., Ingvar, C., Vermeulen, T., Whitehead, K. J., Schmidt, C. W., Palmer, J. M., Symmons, J., Gerdes, Anne-Marie Axø, Jönsson, G. & Hayward, N. K., 2016, In: OncoTarget. 7, 4, p. 4624-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
Vigorito, E., Kuchenbaecker, K. B., Beesley, J., Adlard, J., Agnarsson, B. A., Andrulis, I. L., Arun, B. K., Barjhoux, L., Belotti, M., Benitez, J., Berger, A., Bojesen, A., Bonanni, B., Brewer, C., Caldes, T., Caligo, M. A., Campbell, I., Chan, S. B., Claes, K. B. M., Cohn, D. E. & 126 others, , 2016, In: PLoS ONE. 11, 7, 19 p., e0158801.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients
Bennedbæk, M., Rossing, M., Rasmussen, Å. K., Gerdes, Anne-Marie Axø, Skytte, A., Jensen, U. B., Nielsen, Finn Cilius & Hansen, T. V. O., 2016, In: Hereditary Cancer in Clinical Practice. 14, p. 1-7 7 p., 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D. & 229 others, , 2016, In: Nature Communications. 7, p. 1-13 13 p., 11375.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is screening for pancreatic cancer in high-risk groups cost-effective? Experience from a Danish national screening program
Jøergensen, M. T., Gerdes, Anne-Marie Axø, Sørensen, J., Schaffalitzky de Muckadell, O. & Mortensen, M. B., 2016, In: Pancreatology. 16, 4, p. 584-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
High accuracy of family history of melanoma in Danish melanoma cases
Wadt, K. A. W., Drzewiecki, K. T. & Gerdes, Anne-Marie Axø, Dec 2015, In: Familial Cancer. 14, 4, p. 609-13 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
POLE mutations in families predisposed to cutaneous melanoma
Aoude, L. G., Heitzer, E., Johansson, P., Gartside, M., Wadt, K., Pritchard, A. L., Palmer, J. M., Symmons, J., Gerdes, Anne-Marie Axø, Montgomery, G. W., Martin, N. G., Tomlinson, I., Kearsey, S. & Hayward, N. K., Dec 2015, In: Familial Cancer. 14, 4, p. 621-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnosis of Constitutional Mismatch Repair-Deficiency Syndrome Based on Microsatellite Instability and Lymphocyte Tolerance to Methylating Agents
Bodo, S., Colas, C., Buhard, O., Collura, A., Tinat, J., Lavoine, N., Guilloux, A., Chalastanis, A., Lafitte, P., Coulet, F., Buisine, M-P., Ilencikova, D., Ruiz-Ponte, C., Kinzel, M., Grandjouan, S., Brems, H., Lejeune, S., Blanché, H., Wang, Q., Caron, O. & 31 others, , Oct 2015, In: Gastroenterology. 149, 4, p. 1017-29.e3 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A recurrent germline BAP1 mutation and extension of the BAP1 tumor predisposition spectrum to include basal cell carcinoma
Wadt, K. A. W., Aoude, L. G., Johansson, P., Solinas, A., Pritchard, A., Crainic, O., Andersen, M. T., Kiilgaard, J. F., Heegaard, S., Sunde, L., Federspiel, B., Madore, J., Thompson, J. F., McCarthy, S. W., Goodwin, A., Tsao, H., Jönsson, G., Busam, K., Gupta, R., Trent, J. M. & 4 others, , Sep 2015, In: Clinical Genetics. 88, 3, p. 267-272 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Germline RAD51B truncating mutation in a family with cutaneous melanoma
Wadt, K. A. W., Aoude, L. G., Golmard, L., Hansen, T. V. O., Sastre-Garau, X., Hayward, N. K. & Gerdes, Anne-Marie Axø, Jun 2015, In: Familial Cancer. 14, 2, p. 337-40 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer
Rebbeck, T. R., Mitra, N., Wan, F., Sinilnikova, O. M., Healey, S., McGuffog, L., Mazoyer, S., Chenevix-Trench, G., Easton, D. F., Antoniou, A. C., Nathanson, K. L., Laitman, Y., Kushnir, A., Paluch-Shimon, S., Berger, R., Zidan, J., Friedman, E., Ehrencrona, H., Stenmark-Askmalm, M., Einbeigi, Z. & 31 others, , 7 Apr 2015, In: J A M A: The Journal of the American Medical Association. 313, 13, p. 1347-61 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers
Blanco, I., Kuchenbaecker, K., Cuadras, D., Wang, X., Barrowdale, D., de Garibay, G. R., Librado, P., Sánchez-Gracia, A., Rozas, J., Bonifaci, N., McGuffog, L., Pankratz, V. S., Islam, A., Mateo, F., Berenguer, A., Petit, A., Català, I., Brunet, J., Feliubadaló, L., Tornero, E. & 31 others, , Apr 2015, In: P L o S One. 10, 4, p. 1-18 18 p., e0120020.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Characterization of Melanoma Cases in Denmark Suspected of Genetic Predisposition
Wadt, K. A. W., Aoude, L. G., Krogh, L., Sunde, L., Bojesen, A., Gronskov, K., Wartacz, N., Ek, J., Tolstrup-Andersen, M., Klarskov-Andersen, M., Borg, A., Heegaard, Steffen, Kiilgaard, Jens Folke, Hansen, T. V. O., Klein, K., Jonsson, G., Drzewiecki, K. T., Duno, M., Hayward, N. K. & Gerdes, Anne-Marie Axø, 24 Mar 2015, In: P L o S One. 10, 3, p. 1-16 16 p., e0122662.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a breast cancer family double heterozygote for RAD51C and BRCA2 gene mutations
Ahlborn, L. B., Steffensen, A. Y., Jønson, L., Djursby, M., Nielsen, Finn Cilius, Gerdes, Anne-Marie Axø & Hansen, T. V. O., 18 Mar 2015, In: Familial Cancer. 14, 1, p. 129-133 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of six new susceptibility loci for invasive epithelial ovarian cancer
Kuchenbaecker, K. B., Ramus, S. J., Tyrer, J., Lee, A., Shen, H. C., Beesley, J., Lawrenson, K., McGuffog, L., Healey, S., Lee, J. M., Spindler, T. J., Lin, Y. G., Pejovic, T., Bean, Y., Li, Q., Coetzee, S., Hazelett, D., Miron, A., Southey, M., Terry, M. B. & 31 others, , Feb 2015, In: Nature Genetics. 47, 2, p. 164-71, 3 unpag. p. 11 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma
Aoude, L. G., Pritchard, A. L., Robles-Espinoza, C. D., Wadt, K., Harland, M., Choi, J., Gartside, M., Quesada, V., Johansson, P., Palmer, J. M., Ramsay, A. J., Zhang, X., Jones, K., Symmons, J., Holland, E. A., Schmid, H., Bonazzi, V., Woods, S., Dutton-Regester, K., Stark, M. S. & 19 others, , Feb 2015, In: JNCI - Journal of the National Cancer Institute. 107, 2, p. 1-7 7 p., 408.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers
Peterlongo, P., Chang-Claude, J., Moysich, K. B., Rudolph, A., Schmutzler, R. K., Simard, J., Soucy, P., Eeles, R. A., Easton, D. F., Hamann, U., Wilkening, S., Chen, B., Rookus, M. A., Schmidt, M. K., van der Baan, F. H., Spurdle, A. B., Walker, L. C., Lose, F., Maia, A-T., Montagna, M. & 31 others, , Jan 2015, In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 24, 1, p. 308-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers
Blein, S., Bardel, C., Danjean, V., McGuffog, L., Healey, S., Barrowdale, D., Lee, A., Dennis, J., Kuchenbaecker, K. B., Soucy, P., Terry, M. B., Chung, W. K., Goldgar, D. E., Buys, S. S., Janavicius, R., Tihomirova, L., Tung, N., Dorfling, C. M., van Rensburg, E. J., Neuhausen, S. L. & 31 others, , 2015, In: Breast cancer research : BCR. 17, 1, p. 1-15 15 p., 61.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cowden Syndrome and Concomitant Pulmonary Neuroendocrine Tumor: A Presentation of Two Cases
Langer, Seppo W., Ringholm, L., Dali, C. I., Petersen, René Horsleben, Rasmussen, Å. K., Gerdes, Anne-Marie Axø, Federspiel, B. & Knigge, Ulrich, 2015, In: Case Reports in Medicine. 2015, p. 1-4 4 p., 265786.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Functional characterization of BRCA1 gene variants by mini-gene splicing assay
Steffensen, A. Y., Dandanell, M., Jønson, L., Ejlertsen, B., Gerdes, Anne-Marie Axø, Nielsen, Finn Cilius & Hansen, T. V., Dec 2014, In: European Journal of Human Genetics. 22, 12, p. 1362-1368 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CDKN2A-mutation hos en familie med arveligt malignt melanom
Djursby, M., Wadt, K., Lorentzen, H., Borg, A., Gerdes, Anne-Marie Axø & Krogh, L., 29 Sep 2014, In: Ugeskrift for Laeger. 176, 40, p. 2-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations-a clinical observational study
Bardram, L., Hansen, T. V. O., Gerdes, Anne-Marie Axø, Timshel, S., Friis-Hansen, L. & Federspiel, B., Jun 2014, In: Familial Cancer. 13, 2, p. 231-242 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
Osorio, A., Milne, R. L., Kuchenbaecker, K., Vaclová, T., Pita, G., Alonso, R., Peterlongo, P., Blanco, I., de la Hoya, M., Duran, M., Díez, O., Ramón Y Cajal, T., Konstantopoulou, I., Martínez-Bouzas, C., Andrés Conejero, R., Soucy, P., McGuffog, L., Barrowdale, D., Lee, A., Swe-Brca & 180 others, , Apr 2014, In: P L o S Genetics. 10, 4, p. 1-12 12 p., e1004256.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hereditary breast cancer: clinical, pathological and molecular characteristics
Larsen, M. J., Thomassen, M., Gerdes, Anne-Marie Axø & Kruse, T. A., 2014, In: Breast Cancer: Basic and Clinical Research. 8, p. 145-155 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is Colorectal Neoplasia Part of the Birt-Hogg-Dub Syndrome?
Boman, P. S., Ousager, L. B., Friis-Hansen, L., Hansen, T. V. O., Broesby-Olsen, S. & Gerdes, Anne-Marie Axø, 2014, In: Journal of Gastroenterology and Hepatology Research. 3, 4, p. 1039-1042 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families
Larsen, M. J., Thomassen, M., Tan, Q., Lænkholm, Anne-Vibeke, Bak, M., Sørensen, K. P., Andersen, M. K., Kruse, T. A. & Gerdes, Anne-Marie Axø, 2014, In: B M C Medical Genomics. 7, p. 9Research output: Contribution to journal › Journal article › Research › peer-review
ID: 19459833
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Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
255
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Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
237
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Pediatric cancer families' participation in whole-genome sequencing research in Denmark: Parent perspectives
Research output: Contribution to journal › Journal article › Research › peer-review
Published