Helle Krogh Johansen

Helle Krogh Johansen

Clinical Professor

Member of:

  • Clinical Microbiology


  1. Published

    Hypermutator Pseudomonas Aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients

    Colque, C. A., Albarracín Orio, A. G., Feliziani, S., Marvig, R. L., Tobares, A. R., Johansen, Helle Krogh, Molin, S. & Smania, A. M., Apr 2020, In: Antimicrobial Agents and Chemotherapy. 64, 5, p. e02142-19

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Håndens akutte infektioner

    Søe, Niels Henrik, Jensen, N. V., Dahlin, L. & Johansen, Helle Krogh, 2009, In: Ugeskrift for læger. 171, 14, p. 1189-93 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Immunization with Pseudomonas aeruginosa vaccines and adjuvant can modulate the type of inflammatory response subsequent to infection

    Johansen, Helle Krogh, Espersen, F., Cryz, S. J., Hougen, H. P., Fomsgaard, A., Rygaard, J. & Høiby, Niels, 1994, In: Infection and Immunity. 62, 8, p. 3146-55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Immunomodulatory properties of ginseng. Effects on P. aeruginosa lung infection

    Song, Z. J., Kharazmi, A., Wu, H., Moser, C., Johansen, Helle Krogh, Faber, V. & Høiby, Niels, 1999, In: Clinical Microbiology and Infection. 5, p. 537-538

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

    Yang, L., Haagensen, J. A., Jelsbak, L., Sternberg, C., Høiby, Niels, Molin, S. & Johansen, Helle Krogh, 2008, In: Journal of Bacteriology. 190, 8, p. 2767-2776 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Increased incidence of Mycoplasma pneumoniae infections detected by laboratory-based surveillance in Denmark in 2010

    Rasmussen, J., Voldstedlund, M., R L, A., Ellermann-Eriksen, S., Jensen, T. G., Johansen, Helle Krogh, Kolmos, B., Mølvadgaard, M., Nielsen, S. S., Olsen, E., Schønning, Kristian & Uldum, S. A., 1 Jan 2010, In: Eurosurveillance (Online Edition). 15, 45

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Increasing prevalence of group B streptococcal infection among pregnant women

    Petersen, K. B., Johansen, Helle Krogh, Rosthøj, Susanne, Krebs, Lone, Pinborg, Anja & Hedegaard, M., Sep 2014, In: Danish Medical Journal. 61, 9, p. 1-5 5 p., A4908.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Inhalation devices and inhaled corticosteroids particle size influence on severe pneumonia in patients with chronic obstructive pulmonary disease: a nationwide cohort study

    Heerfordt, C. K., Rønn, C., Harboe, Zitta F B Barrella, Ingebrigtsen, T. S., Svorre Jordan, A., Wilcke, Jon Torgny Rostrup, Bonnesen, B., Biering-Sørensen, Tor, Sørensen, Rikke, Holler, J. G., Itenov, Theis Skovsgaard, Johansen, Helle Krogh, Sivapalan, P., Eklöf, J. & Jensen , Jens-Ulrik Stæhr , 2023, In: BMJ Open Respiratory Research. 10, 1, 10 p., e001814. .

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates

    Tramper-Stranders, G. A., van der Ent, C. K., Molin, S., Yang, L., Hansen, S. K., Rau, M. H., Ciofu, Oana, Johansen, Helle Krogh & Wolfs, T. F. W., Jun 2012, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 18, 6, p. 567-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Inter-species interactions alter antibiotic efficacy in bacterial communities

    Bottery, M. J., Matthews, J. L., Wood, A. J., Johansen, Helle Krogh, Pitchford, J. W. & Friman, V. P., 2022, In: ISME Journal. 16, p. 812–821

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Interferon-gamma (IFN-gamma) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats

    Johansen, Helle Krogh, Hougen, H. P., Rygaard, J. & Høiby, Niels, 1996, In: Clinical and Experimental Immunology. 103, 2, p. 212-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    International BEAT-PCD consensus statement for infection prevention and control for primary ciliary dyskinesia in collaboration with ERN-LUNG PCD Core Network and patient representatives

    Marthin, J. K., Lucas, J. S., Boon, M., Casaulta, C., Crowley, S., Destouches, D. M. S., Eber, E., Escribano, A., Haarman, E., Hogg, C., Maitre, B., Marsh, G., Martinu, V., Moreno-Galdó, A., Mussaffi, H., Omran, H., Pohunek, P., Rindlisbacher, B., Robinson, P., Snijders, D. & 4 others, Walker, W. T., Yiallouros, P., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: ERJ Open Research. 7, 3, 14 p., 00301-2021.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa

    Zuercher, A. W., Horn, M. P., Wu, H., Song, Z. J., Bundgaard, C. J., Johansen, Helle Krogh, Høiby, Niels, Marcus, P. & Lang, A. B., 2006, In: Vaccine. 24, 20, p. 4333-4342 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease: Review

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2016, In: Cochrane Database of Systematic Reviews. 9, p. 1-27 27 p., CD007851.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1 Jan 2010, In: Cochrane Database of Systematic Reviews. 7, p. CD007851

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Intravenous alpha-1 antitrypsin augmentation therapy: systematic review

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1 Sep 2010, In: Danish Medical Bulletin (Online). 57, 9, p. A4175

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways?

    Sommer, L. M., Marvig, R. L., Luján, A., Koza, A., Pressler, T., Molin, S. & Johansen, Helle Krogh, 9 Aug 2016, In: BMC Genomics. 17, 10 p., 589.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Is parotid saliva is sterile on entry to the oral cavity ?

    Schrøder, S., Jensen, A. B., Eickhardt-Dalbøge, S. R., Johansen, Helle Krogh & Homøe, Preben, 2017, In: Acta Oto-Laryngologica. 137, 7, p. 762-764 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review?

    Høiby, Niels & Johansen, Helle Krogh, 2007, In: Journal of Hospital Infection. 65, 4, p. 374-375 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling

    Johansen, H. K., Andersen, L. P., Skinhoj, P., Høiby, Niels & Johansen, Helle Krogh, 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 6. p. 223-298 75 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  21. Published

    Kompendium i mikrobiologi og infektionsmedicin

    Høiby, N., Skinhøj, P., Andersen, Å. B., Andersen, Leif Percival, Arendrup, M. C., Christiansen, C. B., Ciofu, Oana, Gerstoft, Jan, Johansen, Helle Krogh, Kemp, M., Kurtzhals, Jørgen, Nielsen, L. P., Lyngsøe Svejgaard, E., Theander, Thor Grundtvig & Thomsen, Allan Randrup, 2015, 1. ed. FADL's Forlag.

    Research output: Book/ReportBookEducation

  22. Published

    Linezolid in infective endocarditis - it seems to work

    Lauridsen, T., Bruun, L., Rasmussen, R., Moser, Claus Ernst, Johansen, Helle Krogh, Arpi, R. M., Hassager, Christian & Bruun, Niels Eske, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  23. Published

    Long-term evolution of antibiotic tolerance in Pseudomonas aeruginosa lung  infections

    Ghoul, M., Andersen, Sandra Breum, Marvig, R. L., Johansen, Helle Krogh, Jelsbak, L., Molin, S., Perron, G. & Griffin, A. S., 2023, In: Evolution Letters. 7, 6, p. 389–400 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Long-term social dynamics drive loss of function in pathogenic bacteria

    Andersen, Sandra Breum, Marvig, R. L., Molin, S., Johansen, Helle Krogh & Griffin, A. S., 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 34, p. 10756-10761 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams

    Colque, C. A., albarracín Orio, A. G., Tomatis, P. E., Dotta, G., Moreno, D. M., Hedemann, L. G., Hickman, R. A., Sommer, L. M., Feliziani, S., Moyano, A. J., Bonomo, R. A., Johansen, Helle Krogh, Molin, S., Vila, A. J. & Smania, A. M., 2022, In: mBio. 13, 5

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance

    Goltermann, L., Andersen, Kasper Langebjerg, Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1594-1601

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance: author's response

    Goltermann, L., Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1667-1668 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  28. Published

    Mannan-binding lectin is a determinant of survival in infective endocarditis

    Tran, C. T., Kjeldsen, K. E., Haunsø, Stig, Høiby, Niels, Johansen, Helle Krogh & Christiansen, M., 2007, In: Clinical and Experimental Immunology. 148, 1, p. 101-105 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Manzinellaforgiftning kompliceret med streptokokpharyngitis og impetigo

    Bygbjerg, Ib Christian & Johansen, Helle Krogh, 30 Dec 1991, In: Ugeskrift for Laeger. 154, 1, p. 27-8 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics.

    Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh, Bender Koch, Christian & Høiby, Niels, 1996, In: Clinical Microbiology and Infection. 2, 2, p. 91-98 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1997, In: BMJ. British Medical Journal (International Ed.). 314, p. 1238-1244

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms

    Birk, S. E., Haagensen, J. A. J., Johansen, Helle Krogh, Molin, S., Nielsen, L. H. & Boisen, A., May 2020, In: Advanced Healthcare Materials. 9, 10, 10 p., 1901779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.

    Jelsbak, L., Johansen, Helle Krogh, Frost, A., Thøgersen, R., Thomsen, Line Elnif, Ciofu, Oana, Yang, L., Haagensen, J. A. J., Høiby, Niels & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Molecular screening for Candida orthopsilosis and Candida metapsilosis among Danish Candida parapsilosis group blood culture isolates: proposal of a new RFLP profile for differentiation

    Mirhendi, H., Bruun, B., Schønheyder, H. C., Christensen, J. J., Fuursted, K., Gahrn-Hansen, B., Johansen, Helle Krogh, Nielsen, L., Knudsen, J. D. & Arendrup, M. C., 1 Apr 2010, In: Journal of Medical Microbiology. 59, Pt 4, p. 414-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Monitoring meticillin resistant Staphylococcus aureus and its spread in Copenhagen, Denmark, 2013, through routine whole genome sequencing

    Bartels, Mette Damkjær, Larner-Svensson, H., Meiniche, H., Kristoffersen, K., Schønning, Kristian, Nielsen, J. B., Rohde, S. M., Christensen, L. B., Skibsted, A. W., Jarlov, J. O., Johansen, Helle Krogh, Andersen, L. P., Petersen, I. S., Crook, D. W., Bowden, R., Boye, K., Worning, P. & Westh, Henrik T., 30 Apr 2015, In: Eurosurveillance. 20, 17, 9 p., 21112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media

    Homøe, Preben, Bjarnsholt, Thomas, Wessman, M., Sørensen, H. C. F. & Johansen, Helle Krogh, 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients

    Wessman, M., Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R., Johansen, Helle Krogh & Homøe, Preben, May 2015, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 272, 5, p. 1079-1085 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts

    Frimodt-Møller, Jakob, Rossi, E., Haagensen, J. A. J., Falcone, M., Molin, S. & Johansen, Helle Krogh, 2018, In: Scientific Reports. 8, 1, p. 1-13 12512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa

    Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance

    Laborda, P., Lolle, S., Hernando-Amado, S., Alcalde-Rico, M., Aanæs, Kasper, Martínez, J. L., Molin, S. & Johansen, Helle Krogh, 2024, In: Nature Communications. 15, 1, 12 p., 2584.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Mycoplasma hominis-meningitis hos et præmaturt barn med hydrocefalus

    Nielsen, P. E., Poulsen, S., Johansen, Helle Krogh & Greisen, Gorm, 2005, In: Ugeskrift for læger. 167, p. 2416-2417

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Nanograss sensor for selective detection of Pseudomonas aeruginosa by pyocyanin identification in airway samples

    Alatraktchi, F. A. Z. A., Dimaki, M., Støvring, N., Johansen, Helle Krogh, Molin, S. & Svendsen, W. E., Mar 2020, In: Analytical Biochemistry. 593, 6 p., 113586.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    National Surveillance of Fungaemia in Denmark 2004-2009

    Arendrup, M., Christensen, J., Fuursted, K., Johansen, Helle Krogh, Kjeldgaard, P., Knudsen, I. J. D., L, K., Møller, J., Nielsen, L., Olesen, L., Rosenvinge, F., Røder, B., Schønheyder, H., Thomsen, M. & Truberg, K., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  44. Published

    National surveillance of fungemia in Denmark (2004 to 2009)

    Arendrup, M. C., Bruun, B., Christensen, J. J., Fuursted, K., Johansen, Helle Krogh, Kjaeldgaard, P., Knudsen, J. D., Kristensen, L., Møller, J., Nielsen, L., Rosenvinge, F. S., Røder, B., Schønheyder, H. C., Thomsen, M. & Truberg, K., 1 Jan 2011, In: Journal of Clinical Microbiology. 49, 1, p. 325-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    New concepts in antimicrobial resistance in cystic fibrosis respiratory infections

    Drevinek, P., Canton, R., Johansen, Helle Krogh, Hoffman, L., Coenye, T., Burgel, P. & Davies, J. C., 2022, In: Journal of Cystic Fibrosis. 21, 6, p. 937-945 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

    Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Nystatin prophylaxis and treatment in severely immunodepressed patients

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-23 23 p., CD002033.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Omics-based tracking of Pseudomonas aeruginosa persistence in "eradicated" cystic fibrosis patients

    Bartell, J. A., Sommer, L. M., Marvig, R. L., Skov, M., Pressler, T., Molin, S. & Johansen, Helle Krogh, 2021, In: The European Respiratory Journal. 57, 4, 2000512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs

    Ciofu, Oana, Johansen, Helle Krogh, Aanæs, Kasper, Wassermann, T., Alhede, M., von Buchwald, Christian & Høiby, Niels, 8 Mar 2013, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 12, 6, p. 729-736 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa

    Alatraktchi, F. A. Z. A., Noori, J. S., Tanev, G. P., Mortensen, J., Dimaki, M., Johansen, Helle Krogh, Madsen, J., Molin, S. & Svendsen, W. E., 2018, In: PLoS ONE. 13, 3, 9 p., e0194157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease

    Eklöf, J., Misiakou, M. A., Sivapalan, P., Armbruster, K., Browatzki, A., Nielsen, T. L., Lapperre, T. S., Andreassen, H. F., Janner, J., Ulrik, C. S., Gabrielaite, M., Johansen, H. K., Jensen, A., Nielsen, T. V., Hertz, F. B., Ghathian, K., Calum, H., Wilcke, T., Seersholm, N., Jensen, J. U. S. & 1 others, Marvig, R. L., 2022, In: Clinical Microbiology and Infection. 28, 7, p. 990-995 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution

    La Rosa, R., Johansen, Helle Krogh & Molin, S., 2022, In: Antibiotics. 11, 3, 419.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

    Miller, A. K., Brannon, M. K., Stevens, L., Johansen, Helle Krogh, Selgrade, S. E., Miller, S. I., Høiby, Niels & Moskowitz, S. M., 3 Oct 2011, In: Antimicrobial Agents and Chemotherapy. 55, 12, p. 5761-5769

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients

    Moskowitz, S. M., Brannon, M. K., Dasgupta, N., Pier, M., Sgambati, N., Miller, A. K., Selgrade, S. E., Miller, S. I., Denton, M., Conway, S. P., Johansen, Helle Krogh & Høiby, Niels, Feb 2012, In: Antimicrobial Agents and Chemotherapy. 56, 2, p. 1019-1030 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs

    Luján, A. M., Paterson, S., Hesse, E., Sommer, L. M., Marvig, R. L., Sharma, M. D., Alseth, E. O., Ciofu, Oana, Smania, A. M., Molin, S., Johansen, Helle Krogh & Buckling, A., 2022, In: Nature Ecology and Evolution. 6, p. 979–988

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Posttreatment Antifungal Resistance among Colonizing Candida Isolates in Candidemia Patients: Results from a Systematic Multicenter Study

    Jensen, R. H., Johansen, Helle Krogh, Søes, L. M., Lemming, L. E., Rosenvinge, F. S., Nielsen, L., Olesen, B., Kristensen, L., Dzajic, E., Astvad, K. M. T. & Arendrup, M. C., Mar 2016, In: Antimicrobial Agents and Chemotherapy. 60, 3, p. 1500-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Predicting the primary infection source of Escherichia coli bacteremia using virulence-associated genes

    Ilsby, C. S., Hertz, Frederik Boëtius, Westh, Henrik T., Monk, J., Worning, P., Johansen, Helle Krogh, Hansen, Katrine Hartung & Pinholt, M., 2024, In: European Journal of Clinical Microbiology and Infectious Diseases. 43, 4, p. 641-648 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography

    Rasmussen, R. V., Høst, U., Arpi, M., Hassager, Christian, Johansen, Helle Krogh, Korup, E., Schønheyder, H. C., Berning, J., Gill, S., Rosenvinge, F. S., Fowler, V. G., Møller, J. E., Skov, R. L., Larsen, C. T., Hansen, T. F., Mard, S., Smit, J., Andersen, P. S. & Bruun, Niels Eske, 1 Jun 2011, In: European Journal of Echocardiography. 12, 6, p. 414-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

    Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.

    Research output: Contribution to journalLetterResearchpeer-review

  60. Published

    Privatisation rescues function following loss of cooperation

    Andersen, Sandra Breum, Ghoul, M., Marvig, R. L., Lee, Z., Molin, S., Johansen, Helle Krogh & Griffin, A. S., 2018, In: eLife. 7, p. 1-27 27 p., e38594.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Problems in the design and reporting of trials of antifungal agents encountered during meta-analysis

    Johansen, Helle Krogh & Gøtzsche, P. C., 1999, In: JAMA - Journal of the American Medical Association. 282, p. 1752-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.

    Høiby, Niels, Johansen, Helle Krogh, Moser, C., Song, Z., Ciofu, Oana & Kharazmi, A., 2001, In: Microbes and Infection. 3, 1, p. 23-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Pseudomonas aeruginosa diversity in distinct paediatric patient groups

    Tramper-Stranders, G. A., Ent, C. K. V. D., Wolfs, T. F., Kimpen, J. L., Fleer, A., Johansen, U., Høiby, Niels & Johansen, Helle Krogh, 2008, In: Clinical Microbiology and Infection. 14, 10, p. 935-941 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Pseudomonas mendocina as a cause of chronic infective endocarditis in a patient with situs inversus

    Johansen, Helle Krogh, Kjeldsen, K. & Høiby, Niels, 2001, In: Clinical Microbiology and Infection. 7, p. 650-652

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Randomised trial of pivampicillin plus pivmecillinam vs. pivampicillin in children and young adults with chronic obstructive pulmonary disease and infection with Haemophilus influenzae

    Johansen, Helle Krogh, Børch, K., Espersen, F., Koch, C. & Høiby, Niels, 1999, In: Current Medical Research and Opinion. 15(4), p. 300-309

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Rat model of chronic Pseudomonas aeruginosa lung infection

    Johansen, Helle Krogh & Høiby, Niels, 1999, Handbook of animal models of infection. Academic Press, p. 517-526

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  67. Published

    Reconciling Antimicrobial Susceptibility Testing and Clinical Response in Antimicrobial Treatment of Chronic Cystic Fibrosis Lung Infections

    Waters, V. J., Kidd, T. J., Canton, R., Ekkelenkamp, M. B., Johansen, Helle Krogh, LiPuma, J. J., Bell, S. C., Elborn, J. S., Flume, P. A., VanDevanter, D. R., Gilligan, P. & Antimicrobial Resistance International Working Group in Cystic Fibrosis , A. R. I. W. G. I. C. F., 2019, In: Clinical Infectious Diseases. 69, 10, p. 1812-1816

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

    Jensen, Ramon Gordon, Johansen, Helle Krogh, Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R. & Homøe, Preben, Jul 2017, In: European Archives of Oto-Rhino-Laryngology. 274, 7, p. 2741-2747 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice

    de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Routine versus selective antifungal administration for control of fungal infections in patients with cancer

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-48 48 p., CD000026.

    Research output: Contribution to journalReviewResearchpeer-review

  71. Published

    Routine versus selective antifungal administration for control of fungal infections in patients with cancer (Cochrane Review)

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2000, The Cochrane Library, Issue 2. Oxford: Update software, p. -

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  72. Published

    SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients

    Lauridsen, R. K., Sommer, L. M., Johansen, Helle Krogh, Rindzevicius, T., Molin, S., Jelsbak, L., Engelsen, Søren Balling & Boisen, A., 2017, In: Scientific Reports. 7, 7 p., 45264.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization

    Aanæs, Kasper, Johansen, Helle Krogh, Poulsen, Steen Seier, Pressler, T., Buchwald, C. & Høiby, Niels, 2012, In: Journal of Cystic Fibrosis. 12, 1, p. 81-87 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Semi-national surveillance of fungaemia in Denmark 2004-2006: increasing incidence of fungaemia and numbers of isolates with reduced azole susceptibility

    Arendrup, M. C., Fuursted, K., Gahrn-Hansen, B., Schonheyder, H. C., Knudsen, J. D., Jensen, I. M., Bruun, B., Christensen, J. J., Johansen, H. K., Johansen, Helle Krogh & Knudsen, J. D., 2008, In: Clinical Microbiology and Infection. 14, 5, p. 487-494 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia

    Alanin, M. C., Johansen, Helle Krogh, Aanaes, K., Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G. & von Buchwald, Christian, Jan 2015, In: Acta Oto-Laryngologica. 135, 1, p. 58-63 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

    Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia

    Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, Kim G., Johansen, Helle Krogh & von Buchwald, Christian, Mar 2017, In: International Forum of Allergy Rhinology. 7, 3, p. 240-247

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Sinus surgery postpones chronic gram-negative lung infection: Cohort study of 106 patients with cystic fibrosis

    Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, Helle Krogh & von Buchwald, Christian, 2016, In: Rhinology. 54, 3, p. 206-213 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients.

    Johansen, Helle Krogh, Moskowitz, S. M., Ciofu, Oana, Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 5, p. 391-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate

    Halfon, Y., Jimenez-Fernandez, A., La Rosa, R., Espinosa Portero, R., Johansen, Helle Krogh, Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S. & Yonath, A., 29 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22275-22281 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    The Copenhagen Study Group on antibiotics in sweat: Excretion of beta-lactam antibiotics in sweat - a neglected mechanism for development of antibiotic resistance?

    Høiby, Niels, Pers, C., Johansen, Helle Krogh & Hansen, H., 2000, In: Antimicrobial Agents and Chemotherapy. 44, p. 2855-57

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    The accessibility of topical treatment in the paranasal sinuses on operated cystic fibrosis patients assessed by scintigraphy

    Aanæs, Kasper, Alanin, M. C., Nielsen, Kim G., Jørgensen, M. M., von Buchwald, Christian, Høiby, N., Johansen, Helle Krogh, Johannesen, H. H. & Mortensen, Jann, 2018, In: Rhinology. 56, 3, p. 268-273

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    The clinical impact of bacterial biofilms

    Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis

    Aanaes, K., von Buchwald, Christian, Hjuler, Thomas, Skov, M., Alanin, M. & Johansen, Helle Krogh, 2013, In: American Journal of Rhinology & Allergy. 27, 1, p. e1-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    The relation of biofilms to chronic otitis media and other ear related chronic infections

    Homøe, Preben & Johansen, Helle Krogh, 2010, Biofilm Infections. Springer Publishing Company

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  87. Published

    The small RNA ErsA of Pseudomonas aeruginosa contributes to biofilm development and motility through post-transcriptional modulation of AmrZ

    Falcone, M., Ferrara, S., Rossi, E., Johansen, Helle Krogh, Molin, S. & Bertoni, G., 2018, In: Frontiers in Microbiology. 9, FEB, 238.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes

    Pamp, S. J., Gjermansen, M., Johansen, Helle Krogh & Tolker-Nielsen, Tim, 2008, In: Molecular Microbiology. 68, 1, p. 223-40 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial

    Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., Rades, T. & 17 others, Johansen, Helle Krogh, Westh, Henrik T., Kim, W., Mylonakis, E., Friis, C., Guardabassi, Luca, Pace, J., Lundberg, C. V., M'Zali, F., Butty, P., Sørensen, N., Nielsen, H. B., Toft-Kehler, R., Guttman-Yassky, E., Stingl, G., Zeitlinger, M. & Sommer, M., 2022, In: Clinical and Translational Medicine. 12, 5, e790.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Transmission and Antibiotic Resistance of Achromobacter in Cystic Fibrosis

    Gabrielaite, M., Bartell, J. A., Nørskov-Lauritsen, N., Pressler, T., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marviga, R. L., 2021, In: Journal of Clinical Microbiology. 59, 4, e02911-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment

    Lausch, K. R., Søgaard, M., Rosenvinge, F. S., Johansen, Helle Krogh, jfn630, jfn630, Røder, B. L., Mortensen, K. L., Nielsen, L., Lemming, L., Olesen, B., Leitz, C., Kristensen, L., Dzajic, E., Østergaard, L. J., Schønheyder, H. C. & Arendrup, Maiken Cavling, 2018, In: Infection and Drug Resistance. 11, p. 2449-2459 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients

    Nørskov-Lauritsen, N., Johansen, Helle Krogh, Fenger, M. G., Nielsen, X. C., Pressler, T., Olesen, H. V. & Høiby, Niels, 1 Aug 2010, In: Journal of Clinical Microbiology. 48, 8, p. 2981-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Update 2016–2018 of the Nationwide Danish Fungaemia Surveillance Study: Epidemiologic Changes in a 15-Year Perspective

    Risum, M., Astvad, K., Johansen, Helle Krogh, Schønheyder, H. C., Rosenvinge, F., Knudsen, J. D., Hare, R. K., Datcu, R., Røder, B. L., Antsupova, V. S., Kristensen, L., Gertsen, J. B., Møller, J. K., Dzajic, E., Søndergaard, T. S. & Arendrup, Maiken Cavling, 2021, In: Journal of Fungi. 7, 6, 16 p., 491.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Update from a 12-year nationwide fungemia surveillance: Increasing intrinsic and acquired resistance causes concern

    Astvad, K. M. T., Johansen, Helle Krogh, Røder, B. L., Rosenvinge, F. S., Knudsen, J. D., Lemming, L., Schønheyder, H. C., Hare, R. K., Kristensen, L., Nielsen, L., Gertsen, J. B., Dzajic, E., Pedersen, M., Østergård, C., Olesen, B., Søndergaard, T. S. & Arendrup, Maiken Cavling, 1 Apr 2018, In: Journal of Clinical Microbiology. 56, 4, 15 p., e01564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis.

    Høiby, Niels, Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh & Koch, C., 1996, In: Pediatric Infectious Disease Journal. 15, 8, p. 738-43 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Use of inhaled antibiotics among Danish patients with cystic fibrosis

    Møller, R., Nielsen, B. U., Faurholt-Jepsen, D., Katzenstein, T. L., Skov, M., Philipsen, L. K. D., Pressler, T., Johansen, Helle Krogh & Qvist, T., 2022, In: Pediatric Pulmonology. 57, 7, p. 1726-1734 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia in rats

    Johansen, Helle Krogh, Hougen, H. P., Cryz, S. J., Rygaard, J. & Høiby, Niels, 1995, In: American Journal of Respiratory and Critical Care Medicine. 152, 4 Pt 1, p. 1337-46 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia. A new prophylactic principle

    Johansen, Helle Krogh, Cryz, S. J., Hougen, H. P., Moser, Claus Ernst & Høiby, Niels, 1997, In: Behring Institute Mitteilungen. 98, p. 269-73 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

    Johansen, H. K., Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Cochrane Database of Systematic Reviews. 4, p. CD001399

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

    Johansen, Helle Krogh & Gøtzsche, P. C., 2015, In: Cochrane Database of Systematic Reviews. 2015, 8, p. 1-19 19 p., CD001399.

    Research output: Contribution to journalReviewResearchpeer-review

ID: 8804