Helle Krogh Johansen

Helle Krogh Johansen

Clinical Professor

Member of:

  • Clinical Microbiology


  1. 2013
  2. Published

    Clinical effects of sinus surgery and adjuvant therapy in cystic fibrosis patients - can chronic lung infections be postponed?

    Aanæs, Kasper, Johansen, Helle Krogh, Skov, M., Buchvald, F. F., Hjuler, Thomas, Pressler, T., Høiby, Niels, Nielsen, Kim G. & von Buchwald, Christian, 2013, In: Rhinology. 51, 3, p. 222-230 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model

    van de Weert-van Leeuwen, P. B., de Vrankrijker, A. M. M., Fentz, J., Ciofu, Oana, Wojtaszewski, Jørgen F P, Arets, H. G. M., Hulzebos, H. J., van der Ent, C. K., Beekman, J. M. & Johansen, Helle Krogh, 2013, In: P L o S One. 8, 12, 7 p., e82869.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis

    Aanaes, K., von Buchwald, Christian, Hjuler, Thomas, Skov, M., Alanin, M. & Johansen, Helle Krogh, 2013, In: American Journal of Rhinology & Allergy. 27, 1, p. e1-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2012
  6. Published

    Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

    Folkesson, A., Jelsbak, L., Yang, L., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels & Molin, S., Dec 2012, In: Nature Reviews. Microbiology. 10, 12, p. 841-851 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response

    Johansen, Helle Krogh, Aanæs, Kasper, Pressler, T., Nielsen, Kim G., Fisker, J., Skov, M., Høiby, Niels & von Buchwald, Christian, Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 525-531 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa

    Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates

    Tramper-Stranders, G. A., van der Ent, C. K., Molin, S., Yang, L., Hansen, S. K., Rau, M. H., Ciofu, Oana, Johansen, Helle Krogh & Wolfs, T. F. W., Jun 2012, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 18, 6, p. 567-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients

    Moskowitz, S. M., Brannon, M. K., Dasgupta, N., Pier, M., Sgambati, N., Miller, A. K., Selgrade, S. E., Miller, S. I., Denton, M., Conway, S. P., Johansen, Helle Krogh & Høiby, Niels, Feb 2012, In: Antimicrobial Agents and Chemotherapy. 56, 2, p. 1019-1030 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A novel knee prosthesis model of implant-related osteo- myelitis in rats

    Søe, N. H., Jensen, N. V., Nürnberg, B. M., Jensen, Asger Lundorff, Koch, J., Poulsen, Steen Seier, Pier, G. & Johansen, Helle Krogh, 2012, In: Acta Orthopaedica (Print Edition). 84, 1, p. 92-97 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients

    Rasmussen, J., Aanæs, Kasper, Norling, R., Nielsen, K. G., Johansen, Helle Krogh & von Buchwald, C., 2012, In: Journal of Cystic Fibrosis. 11, 2, p. 93-99

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

    Hansen, S. K., Rau, M. H., Johansen, Helle Krogh, Ciofu, Oana, Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, Kasper, von Buchwald, Christian, Høiby, Niels & Molin, S., 2012, In: I S M E Journal. 6, 1, p. 31-45

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Extensive endoscopic image-guided sinus surgery decreases BPI-ANCA in patients with cystic fibrosis

    Aanæs, Kasper, Rasmussen, N., Pressler, T., Segelmark, M., Johansen, Helle Krogh, Lindberg, U., Høiby, Niels, Carlsson, M., Wieslander, J. & Buchwald, C., 2012, In: Scandinavian Journal of Immunology. 76, 6, p. 573-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization

    Aanæs, Kasper, Johansen, Helle Krogh, Poulsen, Steen Seier, Pressler, T., Buchwald, C. & Høiby, Niels, 2012, In: Journal of Cystic Fibrosis. 12, 1, p. 81-87 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2011
  17. Published

    PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients

    Miller, A. K., Brannon, M. K., Stevens, L., Johansen, Helle Krogh, Selgrade, S. E., Miller, S. I., Høiby, Niels & Moskowitz, S. M., 3 Oct 2011, In: Antimicrobial Agents and Chemotherapy. 55, 12, p. 5761-5769

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis

    Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Cystic Fibrosis. 10, 5, p. 318-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Diagnostic Issues, Clinical Characteristics, and Outcomes for Patients with Fungemia

    Arendrup, M. C., Sulim, S., Holm, A., Nielsen, L., Nielsen, S. D., Knudsen, J. D., Drenck, N. E., Christensen, J. J. & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Clinical Microbiology. 49, 9, p. 3300-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance

    Mortensen, K. L., Jensen, R. H., Johansen, Helle Krogh, Skov, M., Pressler, T., Howard, S. J., Leatherbarrow, H., Mellado, E. & Arendrup, M. C., 1 Jun 2011, In: Journal of Clinical Microbiology. 49, 6, p. 2243-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography

    Rasmussen, R. V., Høst, U., Arpi, M., Hassager, Christian, Johansen, Helle Krogh, Korup, E., Schønheyder, H. C., Berning, J., Gill, S., Rosenvinge, F. S., Fowler, V. G., Møller, J. E., Skov, R. L., Larsen, C. T., Hansen, T. F., Mard, S., Smit, J., Andersen, P. S. & Bruun, Niels Eske, 1 Jun 2011, In: European Journal of Echocardiography. 12, 6, p. 414-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Differentiation of Candida glabrata, C. nivariensis and C. bracarensis based on fragment length polymorphism of ITS1 and ITS2 and restriction fragment length polymorphism of ITS and D1/D2 regions in rDNA

    Mirhendi, H., Bruun, B., Schønheyder, H. C., Christensen, J. J., Fuursted, K., Gahrn-Hansen, B., Johansen, Helle Krogh, Nielsen, L., Knudsen, J. D. & Arendrup, M. C., 24 May 2011, In: European Journal of Clinical Microbiology & Infectious Diseases. 30, p. 1409-1416 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility

    Mortensen, K. L., Johansen, Helle Krogh, Fuursted, K., Knudsen, J. D., Gahrn-Hansen, B., Jensen, R. H., Howard, S. & Arendrup, M. C., 4 May 2011, In: European Journal of Clinical Microbiology & Infectious Diseases. 30, 11, p. 1355-1363 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Evolutionary dynamics of bacteria in a human host environment

    Yang, L., Jelsbak, L., Marvig, R. L., Damkiær, S., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels, Sommer, M. & Molin, S., 3 May 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Biofilm ved kronisk rhinosinuitis og cystisk fibrose

    Fisker, J., Buchwald, C. V. & Johansen, Helle Krogh, 7 Feb 2011, In: Ugeskrift for Laeger. 173, 6, p. 417-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    National surveillance of fungemia in Denmark (2004 to 2009)

    Arendrup, M. C., Bruun, B., Christensen, J. J., Fuursted, K., Johansen, Helle Krogh, Kjaeldgaard, P., Knudsen, J. D., Kristensen, L., Møller, J., Nielsen, L., Rosenvinge, F. S., Røder, B., Schønheyder, H. C., Thomsen, M. & Truberg, K., 1 Jan 2011, In: Journal of Clinical Microbiology. 49, 1, p. 325-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

    Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  28. Published

    Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

    Aanæs, Kasper, Rickelt, L. F., Johansen, Helle Krogh, von Buchwald, Christian, Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The clinical impact of bacterial biofilms

    Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2010
  31. Published

    Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain

    Mortensen, K. L., Mellado, E., Lass-Flörl, C., Rodriguez-Tudela, J. L., Johansen, Helle Krogh & Arendrup, M. C., 1 Nov 2010, In: Antimicrobial Agents and Chemotherapy. 54, 11, p. 4545-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Intravenous alpha-1 antitrypsin augmentation therapy: systematic review

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1 Sep 2010, In: Danish Medical Bulletin (Online). 57, 9, p. A4175

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients

    Nørskov-Lauritsen, N., Johansen, Helle Krogh, Fenger, M. G., Nielsen, X. C., Pressler, T., Olesen, H. V. & Høiby, Niels, 1 Aug 2010, In: Journal of Clinical Microbiology. 48, 8, p. 2981-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

    Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, Oana, Johansen, Helle Krogh, Høiby, Niels & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Chronic infection with Stenotrophomonas maltophilia in patients with cystic fibrosis at the Copenhagen CF centre

    Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 17 Jun 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  36. Published

    Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

    Rau, M. H., Hansen, S. K., Johansen, Helle Krogh, Thomsen, L. E., Workman, C. T., Nielsen, K. F., Jelsbak, L., Høiby, Niels, Yang, L. & Molin, S., 1 Jun 2010, In: Environmental Microbiology. 12, 6, p. 1643-58 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Gene transcription profiles of paired mucoid and non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis

    Ciofu, O., Johansen, Helle Krogh, Wassermann, T., Aanæs, Kasper, Alhede, M. & Høiby, Niels, 23 May 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  38. Published

    Diagnosis of bacterial biofilms in chronic sinusitis and pneumonia

    Høiby, Niels, Buchwald, C. V., Aaanæs, K., Pressler, T. & Johansen, Helle Krogh, 10 Apr 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  39. Published

    Molecular screening for Candida orthopsilosis and Candida metapsilosis among Danish Candida parapsilosis group blood culture isolates: proposal of a new RFLP profile for differentiation

    Mirhendi, H., Bruun, B., Schønheyder, H. C., Christensen, J. J., Fuursted, K., Gahrn-Hansen, B., Johansen, Helle Krogh, Nielsen, L., Knudsen, J. D. & Arendrup, M. C., 1 Apr 2010, In: Journal of Medical Microbiology. 59, Pt 4, p. 414-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Increased incidence of Mycoplasma pneumoniae infections detected by laboratory-based surveillance in Denmark in 2010

    Rasmussen, J., Voldstedlund, M., R L, A., Ellermann-Eriksen, S., Jensen, T. G., Johansen, Helle Krogh, Kolmos, B., Mølvadgaard, M., Nielsen, S. S., Olsen, E., Schønning, Kristian & Uldum, S. A., 1 Jan 2010, In: Eurosurveillance (Online Edition). 15, 45

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1 Jan 2010, In: Cochrane Database of Systematic Reviews. 7, p. CD007851

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Active immunization against Staphylococcus aureus (oca+) periprosthetic osteomyelitis in rats

    Koch, J., Johansen, Helle Krogh, Vedel-Jensen, N., Jensen, A., poulsen, S. & Søe, H., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  43. Published

    Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

    Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Effects of antibiotic treatment of Staphylococcus aureus infection in patients with cystic fibrosis at the Copenhagen CF centre

    Dalbøge, C. S., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  45. Published

    Emergence of ESBL-producing Klebsiella pneumoniae in Danish hospitals; this is in part explained by spread of one CTX-M-15 clone in Zealand

    Lester, C., Olsen, S., Arpi, R. M., Fuursted, K., Hansen, D. S., Heltberg, O., Holm, A., Højbjerg, T., Jensen, K., Johansen, Helle Krogh, Justesen, U., Kemp, M., Knudsen, I. J. D., Røder, B., Frimodt-Møller, N. & Hammerum, A., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  46. Published

    Gene transcription profiles of paired mucoid & non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis

    Johansen, Helle Krogh, Wassermann, T., Alhede, M., Aanæs, Kasper, Buchwald, C. V. & Høiby, Niels, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  47. Published

    Linezolid in infective endocarditis - it seems to work

    Lauridsen, T., Bruun, L., Rasmussen, R., Moser, Claus Ernst, Johansen, Helle Krogh, Arpi, R. M., Hassager, Christian & Bruun, Niels Eske, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  48. Published

    National Surveillance of Fungaemia in Denmark 2004-2009

    Arendrup, M., Christensen, J., Fuursted, K., Johansen, Helle Krogh, Kjeldgaard, P., Knudsen, I. J. D., L, K., Møller, J., Nielsen, L., Olesen, L., Rosenvinge, F., Røder, B., Schønheyder, H., Thomsen, M. & Truberg, K., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  49. Published

    The relation of biofilms to chronic otitis media and other ear related chronic infections

    Homøe, Preben & Johansen, Helle Krogh, 2010, Biofilm Infections. Springer Publishing Company

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  50. 2009
  51. Published

    Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media

    Homøe, Preben, Bjarnsholt, Thomas, Wessman, M., Sørensen, H. C. F. & Johansen, Helle Krogh, 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Håndens akutte infektioner

    Søe, Niels Henrik, Jensen, N. V., Dahlin, L. & Johansen, Helle Krogh, 2009, In: Ugeskrift for læger. 171, 14, p. 1189-93 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Respiratory syncytial virus infection facilitates acute colonization of Pseudomonas aeruginosa in mice

    de Vrankrijker, A. M. M., Wolfs, T. F. W., Ciofu, Oana, Høiby, Niels, van der Ent, C. K., Poulsen, Steen Seier & Johansen, Helle Krogh, 2009, In: Journal of Medical Virology. 81, 12, p. 2096-103 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2008
  55. Published

    Har ny teknologi overflødiggjort Grams farvemetode? Dansk Selskab for Klinisk Mikrobiologi

    Johansen, Helle Krogh, Bjarnsholt, Thomas, Høiby, Niels & Dansk Selskab for Klinisk Mikrobiologi, D. S. F. K. M., 17 Mar 2008, In: Ugeskrift for læger. 170, 12, p. 1041

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Den 2. kittelrevolution?

    Høiby, Niels, Johansen, Helle Krogh, Tvede, M. & Andersen, Leif Percival, 2008, In: Ugeskrift for læger. 170, 14, p. 1169

    Research output: Contribution to journalComment/debateResearch

  57. Published

    House dust mite control measures for asthma

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Cochrane Database of Systematic Reviews. 2, p. CD001187-

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    House dust mite control measures for asthma: systematic review

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Allergy. European Journal of Allergy and Clinical Immunology. 63, 6, p. 646-659 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

    Yang, L., Haagensen, J. A., Jelsbak, L., Sternberg, C., Høiby, Niels, Molin, S. & Johansen, Helle Krogh, 2008, In: Journal of Bacteriology. 190, 8, p. 2767-2776 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling

    Johansen, H. K., Andersen, L. P., Skinhoj, P., Høiby, Niels & Johansen, Helle Krogh, 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 6. p. 223-298 75 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  61. Published

    Pseudomonas aeruginosa diversity in distinct paediatric patient groups

    Tramper-Stranders, G. A., Ent, C. K. V. D., Wolfs, T. F., Kimpen, J. L., Fleer, A., Johansen, U., Høiby, Niels & Johansen, Helle Krogh, 2008, In: Clinical Microbiology and Infection. 14, 10, p. 935-941 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Semi-national surveillance of fungaemia in Denmark 2004-2006: increasing incidence of fungaemia and numbers of isolates with reduced azole susceptibility

    Arendrup, M. C., Fuursted, K., Gahrn-Hansen, B., Schonheyder, H. C., Knudsen, J. D., Jensen, I. M., Bruun, B., Christensen, J. J., Johansen, H. K., Johansen, Helle Krogh & Knudsen, J. D., 2008, In: Clinical Microbiology and Infection. 14, 5, p. 487-494 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients.

    Johansen, Helle Krogh, Moskowitz, S. M., Ciofu, Oana, Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 5, p. 391-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes

    Pamp, S. J., Gjermansen, M., Johansen, Helle Krogh & Tolker-Nielsen, Tim, 2008, In: Molecular Microbiology. 68, 1, p. 223-40 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

    Johansen, H. K., Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Cochrane Database of Systematic Reviews. 4, p. CD001399

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. 2007
  67. Published

    Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice

    Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z. J., Johansen, Helle Krogh, Givskov, M. C. & Høiby, Niels, 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-3687 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

    Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Ghost authorship in industry-initiated randomised trials

    Gotzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, Mette Ewers, Altman, D. G. & Chan, A. W., 2007, In: PLoS Medicine. 4, 1, p. 47-52 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review?

    Høiby, Niels & Johansen, Helle Krogh, 2007, In: Journal of Hospital Infection. 65, 4, p. 374-375 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Mannan-binding lectin is a determinant of survival in infective endocarditis

    Tran, C. T., Kjeldsen, K. E., Haunsø, Stig, Høiby, Niels, Johansen, Helle Krogh & Christiansen, M., 2007, In: Clinical and Experimental Immunology. 148, 1, p. 101-105 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.

    Jelsbak, L., Johansen, Helle Krogh, Frost, A., Thøgersen, R., Thomsen, Line Elnif, Ciofu, Oana, Yang, L., Haagensen, J. A. J., Høiby, Niels & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. 2006
  74. Published

    Begrænsninger i publikationsrettighederne i industriinitierede kliniske forsøg: sekundærpublikation

    Gotzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, M. T., Altman, D. G. & Chan, A. W., 2006, In: Ugeskrift for læger. 168, 25, p. 2467-2469 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Constraints on publication rights in industry-initiated clinical trials

    Gøtzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, M. T., Altman, D. G. & Chan, A. W., 2006, In: JAMA - Journal of the American Medical Association. 295, 14, p. 1645-1646 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Flaws in design, analysis and interpretation of Pfizer's antifungal trials of voriconazole and uncritical subsequent quotations

    Jorgensen, K. J., Johansen, Helle Krogh & Gøtzsche, P. C., 2006, In: Trials. 7, p. Art no. 3-

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Fungal infection-related mortality versus total mortality as an outcome in trials of antifungal agents

    Due, A. K., Johansen, Helle Krogh & Gøtzsche, P. C., 2006, In: BMC Medical Research Methodology. 6, p. Art no. 40-

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa

    Zuercher, A. W., Horn, M. P., Wu, H., Song, Z. J., Bundgaard, C. J., Johansen, Helle Krogh, Høiby, Niels, Marcus, P. & Lang, A. B., 2006, In: Vaccine. 24, 20, p. 4333-4342 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Voriconazole versus amphotericin B in cancer patients with neutropenia

    Jorgensen, K. J., Gøtzsche, P. C. & Johansen, Helle Krogh, 2006, In: Cochrane Database of Systematic Reviews. 1, p. Art no. CD004707-

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. 2005
  81. Published

    Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))

    Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  82. Published

    Ginseng modulerer immunresponset via påvirkning af cytokinproduktionen

    Song, Z., Moser, C., Wu, H., Larsen, M. W., Johansen, Helle Krogh, Faber, V., Kharazmi, A. & Høiby, Niels, 2005, In: Ugeskrift for læger. 167, p. 3054-3056

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Mycoplasma hominis-meningitis hos et præmaturt barn med hydrocefalus

    Nielsen, P. E., Poulsen, S., Johansen, Helle Krogh & Greisen, Gorm, 2005, In: Ugeskrift for læger. 167, p. 2416-2417

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

    Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. 2004
  86. Published

    Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success? - A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection

    Johansen, Helle Krogh, Nørregaard, L., Gøtzsche, P. C., Pressler, T., Koch, C. & Høiby, Niels, 2004, In: Pediatric Pulmonology. 37, 5, p. 427-432

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. 2003
  88. Published

    Epidemic spread of Pandoraea apista, a new pathogen causing severe lung disease in cystic fibrosis patients

    Jorgensen, I. M., Johansen, Helle Krogh, Frederiksen, B., Pressler, T., Hansen, A., Vandamme, P., Høiby, Niels & Koch, C., 2003, In: Pediatric Pulmonology. 36(5), p. 439-446

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. 2002
  90. Published

    Amphotericin B lipid soluble formulations vs amphotericin B in cancer patients with neutropenia (Cochrane Review)

    Johansen, Helle Krogh & Gøtzsche, P. C., 2002, The Cochrane Library, Issue 2. Oxford: Update Software (updated), p. -

    Research output: Chapter in Book/Report/Conference proceedingReport chapterResearch

  91. Published

    Er indløsning af en ny antibiotikarecept efter behandling med sulfonamid eller pivmecillinam en validere metode til vurdering af behandlingssvigt?

    Høiby, Niels, Tvede, M. & Johansen, Helle Krogh, 2002, In: Ugeskrift for læger. 164, p. 920-921

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. 2001
  93. Published

    Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis

    Jensen, P., Johansen, Helle Krogh, Carmi, P., Høiby, Niels & Cohen, I. R., 2001, In: J. Autoimmunity. 17, p. 165-172

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Diagnostik ved infektionssygdomme. Pneumoni

    Permin, H., Johansen, Helle Krogh & Høiby, Niels, 2001, In: Ugeskrift for læger. 163, p. 6259-6260

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.

    Høiby, Niels, Johansen, Helle Krogh, Moser, C., Song, Z., Ciofu, Oana & Kharazmi, A., 2001, In: Microbes and Infection. 3, 1, p. 23-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Pseudomonas mendocina as a cause of chronic infective endocarditis in a patient with situs inversus

    Johansen, Helle Krogh, Kjeldsen, K. & Høiby, Niels, 2001, In: Clinical Microbiology and Infection. 7, p. 650-652

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. 2000
  98. Published

    Effects of Radix angelicae sinensis and Shuanghuanglian on a rat model of chronic Pseudomonas aeruginosa pneumonia

    Song, Z. J., Johansen, Helle Krogh, Moser, C., Faber, V., Kharazmi, A., Rygaard, J. & Høiby, Niels, 2000, In: Chinese Medical Sciences Journal. 15(2), p. 83-88

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Routine versus selective antifungal administration for control of fungal infections in patients with cancer (Cochrane Review)

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2000, The Cochrane Library, Issue 2. Oxford: Update software, p. -

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  100. Published

    The Copenhagen Study Group on antibiotics in sweat: Excretion of beta-lactam antibiotics in sweat - a neglected mechanism for development of antibiotic resistance?

    Høiby, Niels, Pers, C., Johansen, Helle Krogh & Hansen, H., 2000, In: Antimicrobial Agents and Chemotherapy. 44, p. 2855-57

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. 1999
  102. Published

    Activation of the immune defence in blood and lung after ginseng treatment in a rat model with chronic Pseudomonas aeruginosa pneumonia

    Song, Z. J., Wu, H., Kharazmi, A., Faber, V., Moser, C., Johansen, Helle Krogh & Høiby, Niels, 1999, In: Netherlands Journal of Medicine. 54, p. 70-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Immunomodulatory properties of ginseng. Effects on P. aeruginosa lung infection

    Song, Z. J., Kharazmi, A., Wu, H., Moser, C., Johansen, Helle Krogh, Faber, V. & Høiby, Niels, 1999, In: Clinical Microbiology and Infection. 5, p. 537-538

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Problems in the design and reporting of trials of antifungal agents encountered during meta-analysis

    Johansen, Helle Krogh & Gøtzsche, P. C., 1999, In: JAMA - Journal of the American Medical Association. 282, p. 1752-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Randomised trial of pivampicillin plus pivmecillinam vs. pivampicillin in children and young adults with chronic obstructive pulmonary disease and infection with Haemophilus influenzae

    Johansen, Helle Krogh, Børch, K., Espersen, F., Koch, C. & Høiby, Niels, 1999, In: Current Medical Research and Opinion. 15(4), p. 300-309

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Rat model of chronic Pseudomonas aeruginosa lung infection

    Johansen, Helle Krogh & Høiby, Niels, 1999, Handbook of animal models of infection. Academic Press, p. 517-526

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  107. 1998
  108. Published

    Effect of ginseng treatment on neutrophil chemiluminescence and IgG subclasses in a rat model of chronic Pseudomonas aeruginosa pneumonia

    Song, Z., Kharazmi, A., Wu, H., Moser, C., Johansen, Helle Krogh, Faber, V., Rygaard, J. & Høiby, Niels, 1998, In: Clinical and Vaccine Immunology. 5, p. 882-887

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. 1997
  110. Published

    Antifungal prophylactic or empiric therapy vs. placebo or no treatment in cancer patients with neutropenia

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1997, Infectious Diseases Module of the Cochrane Database of Systematic Reviews. Oxford: The Cochrane Collaboration, Issue 2

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  111. Published

    Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice

    Moser, Claus Ernst, Johansen, Helle Krogh, Song, Z., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1997, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 105, 11, p. 838-42 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1997, In: BMJ. British Medical Journal (International Ed.). 314, p. 1238-1244

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia. A new prophylactic principle

    Johansen, Helle Krogh, Cryz, S. J., Hougen, H. P., Moser, Claus Ernst & Høiby, Niels, 1997, In: Behring Institute Mitteilungen. 98, p. 269-73 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. 1996
  115. Published

    Interferon-gamma (IFN-gamma) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats

    Johansen, Helle Krogh, Hougen, H. P., Rygaard, J. & Høiby, Niels, 1996, In: Clinical and Experimental Immunology. 103, 2, p. 212-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics.

    Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh, Bender Koch, Christian & Høiby, Niels, 1996, In: Clinical Microbiology and Infection. 2, 2, p. 91-98 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis.

    Høiby, Niels, Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh & Koch, C., 1996, In: Pediatric Infectious Disease Journal. 15, 8, p. 738-43 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. 1995
  119. Published

    Experimental chronic Pseudomonas aeruginosa lung infection in rats. Non-specific stimulation with LPS reduces lethality as efficiently as specific immunization

    Lange, Kai, Hougen, H. P., Høiby, Niels, Fomsgaard, A., Rygaard, J. & Johansen, Helle Krogh, 1995, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 103, 5, p. 367-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 8804