Inge Marie Svane

Inge Marie Svane

Clinical Professor

Member of:

  • Clinical Oncology


  1. 2012
  2. Published

    Characterization and comparison of "Standard" and "Young" tumor infiltrating lymphocytes for adoptive cell therapy at a Danish Translational Research Institution

    Donia, M., Junker, N., Ellebaek, E., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2012, In: Scandinavian Journal of Immunology. 75, 2, p. 157-167 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Characterization of Spontaneous Immune Responses against Long Peptides Derived from Bcl-X(L) in Cancer Patients Using Elispot

    Svane, Inge Marie, Straten, P. T., Andersen, M. H., Larsen, S. K. & Hansen, M., 2012, In: Cells. 1, 2, p. 51-60 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Characterization of T-cell responses against IκBα in cancer patients

    Munir, S., Frøsig, T. M., Hansen, M., Svane, Inge Marie & Andersen, M. H., 2012, In: OncoImmunology. 1, 8, p. 1290-1296 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Comment on "Adoptive T-cell therapy for malignant melanoma patients with TILs obtained by ultrasound-guided needle biopsy" by Gustav J. Ullenhag et al

    Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 5, p. 747; author reply 749

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Dissection of T-cell antigen specificity in human melanoma

    Andersen, R. S., Albæk Thrue, C., Junker, N., Skou, R. B. L., Donia, M., Ellebæk, E., Svane, Inge Marie, Schumacher, T. N., Thor Straten, P. & Hadrup, S. R., 2012, In: Cancer Research. 72, 7, p. 1642-50 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effector and regulatory T cells in patients with acute optic neuritis

    Tsakiri, A., Kjærsgaard, E., Grigoriadis, N., Svane, Inge Marie & Frederiksen, J. L., 2012, In: Neuroimmunomodulation. 19, 2, p. 111-20 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Generation of autologous tumor-specific T cells for adoptive transfer based on vaccination, in vitro restimulation and CD3/CD28 dynabead-induced T cell expansion

    Brimnes, M. K., Gang, A. O., Donia, M., Thor Straten, P., Svane, Inge Marie & Hadrup, S. R., 2012, In: Cancer Immunology, Immunotherapy. 61, 8, p. 1221-31 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    IFN-γ to improve immunotherapy for melanoma

    Donia, M., Svane, Inge Marie, Andersen, M. H., Hansen, M., Straten, P. T., Ellebæk, E., Iversen, T. Z. & SL, S., 2012. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  10. Published

    Immunotherapy for metastatic colorectal cancer: Present status and new options

    Ellebaek, E., Andersen, M. H., Svane, Inge Marie & Straten, P. T., 2012, In: Scandinavian Journal of Gastroenterology. 47, 3, p. 315-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial

    Ellebaek, E., Engell-Noerregaard, L., Iversen, T. Z., Moerch Froesig, T., Munir, S., Hadrup, S. R., Andersen, M. H. & Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 10, p. 1791-1804 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase

    Munir, S., Larsen, S. K., Iversen, T. Z., Donia, M., Klausen, T. W., Svane, Inge Marie, Straten, P. T. & Andersen, M. H., 2012, In: P L o S One. 7, 4, p. e34568

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Tumor associated antigen specific T-cell populations identified in ex vivo expanded TIL cultures

    Junker, N., Kvistborg, P., Køllgaard, T., Straten, P. T., Andersen, Mads Hald & Svane, Inge Marie, 2012, In: Cellular Immunology. 273, 1, p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2013
  15. Published

    Analysis of Survivin-Specific T Cells in Breast Cancer Patients Using Human DCs Engineered with Survivin mRNA

    Met, Özcan & Svane, Inge Marie, 2013, Synthetic Messenger RNA and Cell Metabolism Modulation. Vol. 969. p. 275-292 18 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy

    Hansen, M., Hjortø, Gertrud Malene, Donia, M., Met, Özcan, Larsen, N. B., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2013, In: Vaccine. 31, 4, p. 639-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients

    Iversen, T. Z., Brimnes, M. K., Nikolajsen, K., Andersen, R. S., Hadrup, S. R., Andersen, M. H., Bastholt, L. & Svane, Inge Marie, 2013, In: OncoImmunology. 2, 2, p. 1-10 10 p., e23288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    FDG PET scans as evaluation of clinical response to dendritic cell vaccination in patients with malignant melanoma

    Engell-Noerregaard, L., Hendel, H. W., Johannesen, H. H., Alslev, L. & Svane, Inge Marie, 2013, In: Cancer Immunology, Immunotherapy. 62, 1, p. 17-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Methods to Improve Adoptive T-Cell Therapy for Melanoma: IFN-γ Enhances Anticancer Responses of Cell Products for Infusion

    Donia, M., Hansen, M., Sendrup, S. L., Iversen, T. Z., Ellebæk, E., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2013, In: Journal of Investigative Dermatology. 133, 2, p. 545-52 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Silencing of the glucocorticoid-induced leucine zipper improves the immunogenicity of clinical-grade dendritic cells

    Cathelin, D., Met, Özcan & Svane, Inge Marie, 2013, In: Cytotherapy. 15, 6, p. 740-749 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4(+) T cells

    Munir, S., Andersen, G. H., Svane, Inge Marie & Andersen, Mads Hald, 2013, In: OncoImmunology. 2, 4, 9 p., e23991.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients

    Munir, S., Andersen, G. H., Met, Özcan, Donia, M., Frøsig, T. M., Larsen, S. K., Klausen, T. W., Svane, Inge Marie & Andersen, Mads Hald, 15 Mar 2013, In: Cancer Research. 73, 6, p. 1764-76 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Functional characterization of Foxp3-specific spontaneous immune responses

    Larsen, S. K., Munir, S., Woetmann, Anders , Frøsig, T. M., Ødum, Niels, Svane, Inge Marie, Becker, J. C. & Andersen, Mads Hald, Dec 2013, In: Leukemia. 27, 12, p. 2332-40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    In-chip fabrication of free-form 3D constructs for directed cell migration analysis

    Olsen, M. H., Hjortø, Gertrud Malene, Hansen, M., Met, Özcan, Svane, Inge Marie & Larsen, N. B., 21 Dec 2013, In: Lab On a Chip. 13, 24, p. 4800-4809 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2014
  26. Published

    Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?

    Svane, Inge Marie & Verdegaal, E. M., 2014, In: Cancer immunology, immunotherapy : CII. 63, 10, p. 1081-1091 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway

    Ahmad, S. M., Larsen, S. K., Svane, Inge Marie & Andersen, M. H., Jan 2014, In: Leukemia. 28, 1, p. 236-238 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Long-lasting Disease Stabilization in the Absence of Toxicity in Metastatic Lung Cancer Patients Vaccinated with an Epitope Derived from Indoleamine 2,3 Dioxygenase

    Iversen, T. Z., Engell-Noerregaard, L., Ellebaek, E., Andersen, R. S., Larsen, S. K., Bjoern, J., Zeyher, C., Gouttefangeas, C., Thomsen, B. M., Holm, B., Thor Straten, P., Mellemgaard, A., Andersen, Mads Hald & Svane, Inge Marie, 1 Jan 2014, In: Clinical Cancer Research. 20, 1, p. 221-232 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Spontaneous presence of FOXO3-specific T cells in cancer patients

    Larsen, S. K., Ahmad, S. M., Idorn, M., Met, Özcan, Martinenaite, E., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 1 Jan 2014, In: OncoImmunology. 3, 8, e953411.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Late development of splenic sarcoidosis-like lesions in a patient with metastatic melanoma and long-lasting clinical response to ipilimumab

    Andersen, R., Nørgaard, P. H., Al-Jailawi, M. K. M. & Svane, Inge Marie, 23 Jan 2014, In: OncoImmunology. 3, 8, e954506.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Simplified protocol for clinical-grade tumor-infiltrating lymphocyte manufacturing with use of the Wave bioreactor

    Donia, M., Larsen, S. M., Met, Özcan & Svane, Inge Marie, Aug 2014, In: Cytotherapy. 16, 8, p. 1117–1120 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Successful treatment with Ipilimumab and Interleukin‑2 in two patients with metastatic melanoma and systemic autoimmune disease

    Pedersen, M., Andersen, R., Larsen, P. N., Jacobsen, Søren, Thielsen, P., Thor Straten, P. & Svane, Inge Marie, Dec 2014, In: Cancer immunology, immunotherapy : CII. 63, 12, p. 1341-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2015
  34. Published

    Indoleamine 2,3-dioxygenase vaccination

    Andersen, Mads Hald & Svane, Inge Marie, 2015, In: OncoImmunology. 4, 1, p. 1-3 3 p., e983770.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma

    Andersen, R., Donia, M., Westergaard, M. C. W., Pedersen, M., Hansen, M. & Svane, Inge Marie, 2015, In: Human Vaccines & Immunotherapeutics. 11, 12, p. 2790-5 6 p.

    Research output: Contribution to journalComment/debateResearch

  36. Published

    Antibody Stabilization of Peptide–MHC Multimers Reveals Functional T Cells Bearing Extremely Low-Affinity TCRs

    Tungatt, K., Bianchi, V., Crowther, M. D., Powell, W. E., Schauenburg, A. J., Trimby, A., Donia, M., Miles, J. J., Holland, C. J., Cole, D. K., Godkin, A. J., Peakman, M., Straten, P. T., Svane, Inge Marie, Sewell, A. K. & Dolton, G., Jan 2015, In: Journal of immunology (Baltimore, Md. : 1950). 194, 1, p. 463-474 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The Targeting of Indoleamine 2,3 Dioxygenase -Mediated Immune Escape in Cancer

    Iversen, T. Z., Andersen, Mads Hald & Svane, Inge Marie, Jan 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 1, p. 19-24 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Tryptophan 2,3-dioxygenase (TDO)-reactive T cells differ in their functional characteristics in health and cancer

    Hjortsø, M. D., Larsen, S. K., Kongsted, P., Met, Özcan, Frøsig, T. M., Andersen, G. H., Ahmad, S. M., Svane, Inge Marie, Becker, J. C., Straten, P. T. & Andersen, Mads Hald, Jan 2015, In: OncoImmunology. 4, 1, e968480.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α

    Riley, C. H., Hansen, M., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., Straten, P. T., Svane, Inge Marie & Jensen, M. K., Mar 2015, In: European Journal of Haematology. 94, 3, p. 227–234 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Confinement dependent chemotaxis in two-photon polymerized linear migration constructs with highly definable concentration gradients

    Hjortø, Gertrud Malene, Olsen, M. H., Svane, Inge Marie & Larsen, N. B., Apr 2015, In: Biomedical Microdevices. 17, 2, p. 1-10 10 p., 30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial

    Weber, J. S., D'Angelo, S. P., Minor, D., Hodi, F. S., Gutzmer, R., Neyns, B., Hoeller, C., Khushalani, N. I., Miller, W. H., Lao, C. D., Linette, G. P., Thomas, L., Lorigan, P., Grossmann, K. F., Hassel, J. C., Maio, M., Sznol, M., Ascierto, P. A., Mohr, P., Chmielowski, B. & 8 others, Bryce, A., Svane, Inge Marie, Grob, J., Krackhardt, A. M., Horak, C., Lambert, A., Yang, A. S. & Larkin, J., Apr 2015, In: Lancet Oncology. 16, 4, p. 375-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Broadening the repertoire of melanoma-associated T-cell epitopes

    Frøsig, T. M., Lyngaa, R., Met, Özcan, Larsen, S. K., Donia, M., Svane, Inge Marie, Thor Straten, P. & Hadrup, S. R., May 2015, In: Cancer immunology, immunotherapy : CII. 64, 5, p. 609-20 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Neuroprotective and anti-inflammatory mechanisms are activated early in optic neuritis

    Tsakiri, A., Ravanidis, S., Lagoudaki, R., Poulatsidou, K., Svane, Inge Marie, Fredriksen, Jette Lautrup & Grigoriadis, N., May 2015, In: Acta Neurologica Scandinavica. 131, 5, p. 305-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers

    Dolton, G., Tungatt, K., Lloyd, A., Bianchi, V., Theaker, S. M., Trimby, A., Holland, C. J., Donia, M., Godkin, A. J., Cole, D. K., Straten, P. T., Peakman, M., Svane, Inge Marie & Sewell, A. K., Sep 2015, In: Immunology. 146, 1, p. 11-22 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Reorienting the immune system in the treatment of cancer by using anti-PD-1 and anti-PD-L1 antibodies

    Borch, T. H., Donia, M., Andersen, Mads Hald & Svane, Inge Marie, Sep 2015, In: Drug Discovery Today. 20, 9, p. 1127-34 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity

    Donia, M., Andersen, R., Kjeldsen, J. W., Fagone, P., Munir, S., Nicoletti, F., Andersen, Mads Hald, Thor Straten, P. & Svane, Inge Marie, 15 Sep 2015, In: Cancer Research. 75, 18, p. 3747-59 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05

    Frøsig, T. M., Yap, J., Seremet, T., Lyngaa, R., Svane, Inge Marie, Thor Straten, P., Heemskerk, M. H. M., Grotenbreg, G. M. & Hadrup, S. R., Oct 2015, In: Cytometry. Part A. 87, 10, p. 967-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Low-dose prednisolone in first-line docetaxel for patients with metastatic castration-resistant prostate cancer: is there a clinical benefit?

    Kongsted, P., Svane, Inge Marie, Lindberg, H., Daugaard, G. & Sengeløv, L., Nov 2015, In: Urologic Oncology: Seminars and Original Investigations. 33, 11, p. 494.e15-20

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Tumor-infiltrating lymphocytes for the treatment of metastatic cancer

    Geukes Foppen, M. H., Donia, M., Svane, Inge Marie & Haanen, J. B. A. G., Dec 2015, In: Molecular Oncology. 9, 10, p. 1918-35 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. 2016
  51. Published

    Behandlingen af BRAF-muteret metastatisk melanom med BRAF/MEK-inhibitorer bedrer prognosen

    Boyles, T. B., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V02160126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment

    Martinenaite, E., Munir Ahmad, S., Hansen, M., Met, Özcan, Westergaard, M. W., Larsen, S. K., Klausen, T. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2016, In: OncoImmunology. 5, 11, 10 p., e1238541.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Immuncheckpointantistoffer øger overlevelsen for patienter med metastatisk melanom

    Fløe, L. E., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V01160070.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Immune monitoring using mRNA-transfected dendritic cells

    Borch, T. H., Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Humana Press, Vol. 1428. p. 245-259 15 p. (Methods in Molecular Biology, Vol. 1428).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  55. Published

    Immunological correlates of treatment and response in stage IV malignant melanoma patients treated with Ipilimumab

    Bjoern, J., Juul Nitschke, N., Zeeberg Iversen, T., Schmidt, H., Fode, K. & Svane, Inge Marie, 2016, In: OncoImmunology. 5, 4, 10 p., e1100788.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4054758