Inge Marie Svane
Clinical Professor
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of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes
Hulen, T. M., Friese, C., Kristensen, N. P., Granhøj, J. S., Borch, T. H., Peeters, M. J. W., Donia, M., Andersen, Mads Hald, Hadrup, S. R., Svane, Inge Marie & Met, Özcan, 2023, In: Frontiers in Immunology. 14, 15 p., 1180997.Research output: Contribution to journal › Journal article › Research › peer-review
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A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma
Kjeldsen, J. W., Lorentzen, C. L., Martinenaite, E., Ellebaek, E., dqp123, dqp123, Holmstroem, R. B., Klausen, T. W., Madsen, C. O., Ahmed, S. M., Weis-Banke, S. E., Holmström, M. O., Hendel, Helle Westergren, Ehrnrooth, E., Zocca, M. B., Pedersen, A. W., Andersen, Mads Hald & Svane, Inge Marie, 2021, In: Nature Medicine. 27, p. pages2212–2223Research output: Contribution to journal › Journal article › Research › peer-review
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A promiscuous survivin-derived T-cell epitope restricted to the HLA-A3 super-type alleles
Junker, N., Munir, S., Kvistborg, P., Straten, P. T., Svane, Inge Marie & Andersen, M. H., 2012, In: Journal of Investigative Dermatology. 132, 8, p. 2115-2118 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ACT Up TIL Now: The Evolution of Tumor-Infiltrating Lymphocytes in Adoptive Cell Therapy for the Treatment of Solid Tumors
Morgan Hulen , T., Chamberlain, C. A., Svane, Inge Marie & Met, Özcan, 2021, In: Immuno. 1, 3, p. 194-211Research output: Contribution to journal › Journal article › Research › peer-review
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ASO Visual Abstract: Earlier Recurrence Detection Using Routine FDG PET-CT Scans in Surveillance of Stage IIB to IIID Melanoma-A National Cohort Study of 1480 Patients
Helvind, N. M., Weitemeyer, M. B. M., Chakera, A. H., Hendel, Helle Westergren, Ellebæk, E., Svane, Inge Marie, Kjærskov, M. W., Bojesen, S., Skyum, H., Petersen, S. K., Bastholt, L., Johansen, Christoffer, Bidstrup, P. E. & Hølmich, Lisbet Rosenkrantz, 2023, In: Annals of Surgical Oncology. 30, 4, p. 2389-2390 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity
Donia, M., Andersen, R., Kjeldsen, J. W., Fagone, P., Munir, S., Nicoletti, F., Andersen, Mads Hald, Thor Straten, P. & Svane, Inge Marie, 15 Sep 2015, In: Cancer Research. 75, 18, p. 3747-59 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?
Svane, Inge Marie & Verdegaal, E. M., 2014, In: Cancer immunology, immunotherapy : CII. 63, 10, p. 1081-1091 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling
Donia, M., Harbst, K., van Buuren, M., Kvistborg, P., Lindberg, M. F., Andersen, R., Idorn, M., Munir Ahmad, S., Ellebæk, E., Mueller, A., Fagone, P., Nicoletti, F., Libra, M., Lauss, M., Hadrup, S. R., Schmidt, H., Andersen, M. H., Thor Straten, P., Nilsson, J. A., Schumacher, T. N. & 3 others, , 1 Sep 2017, In: Cancer Research. 77, 17, p. 4562-4566 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Addition of interferon-alpha to a standard maturation cocktail induces CD38 up-regulation and increases dendritic cell function
Trepiakas, R., Pedersen, Anders Elm, Met, Özcan & Svane, Inge Marie, 2009, In: Vaccine. 27, 16, p. 2213-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adoptive cell therapy in combination with checkpoint inhibitors in ovarian cancer
Kverneland, Anders Handrup, Pedersen, M., Wulff Westergaard, M. C., Nielsen, M., Borch, T. H., Olsen, L. R., Aasbjerg, G., Santegoets, S. J., van der Burg, S. H., Milne, K., Nelson, B. H., Met, Özcan, dqp123, dqp123 & Svane, Inge Marie, 2020, In: OncoTarget. 11, 22, p. 2092-2105 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients
Ellebaek, E., Iversen, T. Z., Junker, N., Donia, M., Engell-Noerregaard, L., Met, Özcan, Hølmich, Lisbet Rosenkrantz, Andersen, R. S., Hadrup, S. R., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2012, In: Journal of Translational Medicine. 10, p. 169Research output: Contribution to journal › Journal article › Research › peer-review
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Adoptive cell therapy with tumor-infiltrating lymphocytes in patients with metastatic ovarian cancer: a pilot study
Pedersen, M., Westergaard, M. C. W., Milne, K., Nielsen, M., Borch, T. H., Poulsen, L. G., Hendel, Helle Westergren, Kennedy, M., Briggs, G., Ledoux, S., Nøttrup, T. J., Andersen, P., Hasselager, T., Met, Ö., Nelson, B. H., dqp123, dqp123 & Svane, Inge Marie, 2018, In: OncoImmunology. 7, 12, 12 p., e1502905.Research output: Contribution to journal › Journal article › Research › peer-review
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Age favoured overall survival in a large population-based Danish patient cohort treated with anti-PD1 immune checkpoint inhibitor for metastatic melanoma
Bastholt, L., Schmidt, H., Bjerregaard, J. K., Herrstedt, Jørn & Svane, Inge Marie, Sep 2019, In: European journal of cancer (Oxford, England : 1990). 119, p. 122-131 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An arginase1- and PD-L1-derived peptide-based vaccine for myeloproliferative neoplasms: A first-in-man clinical trial
Grauslund, J. H., Holmström, M. O., Martinenaite, E., Lisle, T. L., Glöckner, H. J., Fassi, Daniel El , Klausen, U., Mortensen, R. E. J., Jørgensen, N., Kjær, L., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2023, In: Frontiers in Immunology. 14, 14 p., 1117466.Research output: Contribution to journal › Journal article › Research › peer-review
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An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma
Klausen, U., Grønne Dahlager Jørgensen, N., Grauslund, J. H., Munir Ahmad, S., Gang, Anne Ortved, Martinenaite, E., Weis-Banke, S. E., Breinholt, M. F., Novotny, G. W., Kjeldsen, J. W., Orebo Holmström, M., Pedersen, L. B., Poulsen, C. B., Hansen, P. B., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2021, In: OncoImmunology. 10, 1, 1975889.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of Survivin-Specific T Cells in Breast Cancer Patients Using Human DCs Engineered with Survivin mRNA
Met, Özcan & Svane, Inge Marie, 2013, Synthetic Messenger RNA and Cell Metabolism Modulation. Vol. 969. p. 275-292 18 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes
Donia, M., Ellebaek, E., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2012, In: OncoImmunology. 1, 8, p. 1297-1304 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV
Klausen, U., Grauslund, J. H., Jørgensen, N. G. D., Ahmad, S. M., Jonassen, M., Weis-Banke, S. E., Martinenaite, E., Pedersen, L. B., Lisle, T. L., Gang, Anne Ortved, Enggaard, L., Hansen, M., Holmström, M. O., Met, Özcan, Svane, Inge Marie, Niemann, Carsten, Pedersen, Lars Møller & Andersen, Mads Hald, 2022, In: Frontiers in Oncology. 12, 1023015.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody Stabilization of Peptide–MHC Multimers Reveals Functional T Cells Bearing Extremely Low-Affinity TCRs
Tungatt, K., Bianchi, V., Crowther, M. D., Powell, W. E., Schauenburg, A. J., Trimby, A., Donia, M., Miles, J. J., Holland, C. J., Cole, D. K., Godkin, A. J., Peakman, M., Straten, P. T., Svane, Inge Marie, Sewell, A. K. & Dolton, G., Jan 2015, In: Journal of immunology (Baltimore, Md. : 1950). 194, 1, p. 463-474 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Arginase-1 targeting peptide vaccine in patients with metastatic solid tumors – A phase I trial
Lorentzen, C. L., Martinenaite, E., Kjeldsen, J. W., Holmstroem, R. B., Mørk, S. K., Pedersen, A. W., Ehrnrooth, E., Andersen, Mads Hald & Svane, Inge Marie, 2022, In: Frontiers in Immunology. 13, 1023023.Research output: Contribution to journal › Journal article › Research › peer-review
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Arginase-1-based vaccination against the tumor microenvironment: the identification of an optimal T-cell epitope
Martinenaite, E., Ahmad, S. M., Bendtsen, S. K., Jørgensen, M. A., Weis-Banke, S. E., Svane, Inge Marie & Andersen, Mads Hald, 2019, In: Cancer Immunology, Immunotherapy. 68, 11, p. 1901-1907 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells
Weis-Banke, S. E., Lisle, T. L., Perez Penco, Maria, Schina, A., Hübbe, M. L., Siersbæk, M., Holmström, M. O., Jørgensen, M. A., Svane, Inge Marie, Met, Özcan, Ødum, Niels, Madsen, Daniel Hargbøl, dqp123, dqp123, Grøntved, L. & Andersen, Mads Hald, 2022, In: Journal for ImmunoTherapy of Cancer. 10, 10, e005326.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of extracellular matrix and tissue derived metabolites in a liquid biopsy for identifying endotypes of metastatic melanoma patients with differential response to immune checkpoint inhibitor treatment.
Willumsen, N., Bager, C. L., Jensen, C., Karsdal, M. A., Madsen, Daniel Hargbøl, Hansen, M., Schmidt, H. & Svane, Inge Marie, 2019, In: Journal of Clinical Oncology. 37, 15_suppl, e14050.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Autocrine CCL19 blocks dendritic cell migration toward weak gradients of CCL21
Hansen, M., Met, Özcan, Larsen, N. B., Rosenkilde, Mette, Andersen, Mads Hald, Svane, Inge Marie & Hjortø, Gertrud Malene, Sep 2016, In: Cytotherapy. 18, 9, p. 1187-1196Research output: Contribution to journal › Journal article › Research › peer-review
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B Cells and Tertiary Lymphoid Structures: Friends or Foes in Cancer Immunotherapy?
Lauss, M., dqp123, dqp123, Svane, Inge Marie & Jönsson, G., 2022, In: Clinical Cancer Research. 28, 9, p. 1751–1758 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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B-cell frequencies and immunoregulatory phenotypes in myeloproliferative neoplasms: influence of ruxolitinib, interferon-α2, or combination treatment
Sørensen, A. L., Bjørn, M. E., Riley, C. H., Holmstrøm, M., Andersen, Mads Hald, Svane, Inge Marie, Mikkelsen, S. U., Skov, V., Kjær, L., Hasselbalch, H. C. & Nielsen, C. H., 2019, In: European Journal of Haematology. 103, 4, p. 351-361 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer
Donia, M., Fagone, P., Nicoletti, F., Andersen, R. S., Høgdall, E., Straten, P. T., Andersen, M. H. & Svane, Inge Marie, 2012, In: OncoImmunology. 1, 9, p. 1476-1483 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Behandlingen af BRAF-muteret metastatisk melanom med BRAF/MEK-inhibitorer bedrer prognosen
Boyles, T. B., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V02160126.Research output: Contribution to journal › Journal article › Research › peer-review
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Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., von Buchwald, Christian, Andersen, E., Straten, P. T. & Svane, Inge Marie, 2011, In: Cytotherapy. 13, 7, p. 822-34 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., Buchwald, C. V., Andersen, E., Straten, P. T., Svane, Inge Marie & Andersen, Mads Hald, 24 Mar 2011, In: Cytotherapy. 13, 7, p. 822-34Research output: Contribution to journal › Journal article › Research › peer-review
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Bone marrow toxicity and immune reconstitution in melanoma and non-melanoma solid cancer patients after non-myeloablative conditioning with chemotherapy and checkpoint inhibition
Kverneland, Anders Handrup, Borch, T. H., Granhøj, J., Sengeløv, Henrik, Donia, M. & Svane, Inge Marie, Aug 2021, In: Cytotherapy. 23, 8, p. 724-729 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Broadening the repertoire of melanoma-associated T-cell epitopes
Frøsig, T. M., Lyngaa, R., Met, Özcan, Larsen, S. K., Donia, M., Svane, Inge Marie, Thor Straten, P. & Hadrup, S. R., May 2015, In: Cancer immunology, immunotherapy : CII. 64, 5, p. 609-20 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment
Martinenaite, E., Munir Ahmad, S., Hansen, M., Met, Özcan, Westergaard, M. W., Larsen, S. K., Klausen, T. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2016, In: OncoImmunology. 5, 11, 10 p., e1238541.Research output: Contribution to journal › Journal article › Research › peer-review
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CD8 T-cell responses against cyclin B1 in breast cancer patients with tumors overexpressing p53
Sørensen, R. B., Andersen, R. S., Svane, Inge Marie, Engell-Noerregaard, L., Hadrup, S. R., Balslev, E., Andersen, Mads Hald & thor Straten, P., 2009, In: Clinical Cancer Research. 15, 5, p. 1543-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis
Holmstroem, R. B., Nielsen, Ole Haagen, Jacobsen, Søren, Riis, Lene Buhl, Theile, S., Bjerrum, Jakob Tveiten , Vilmann, Peter, Johansen, Julia Sidenius, Boisen, M. K., Eefsen, R. H. L., Svane, Inge Marie, Nielsen, Dorte Lisbet & Chen, I. M., 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9Research output: Contribution to journal › Journal article › Research › peer-review
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CTLA-4 blockade boosts the expansion of tumor-reactive CD8+ tumor-infiltrating lymphocytes in ovarian cancer
Friese, C., Harbst, K., Borch, T. H., Westergaard, M. C. W., Pedersen, M., Kverneland, A., Jönsson, G., dqp123, dqp123, Svane, Inge Marie & Met, Özcan, 2020, In: Scientific Reports. 10, 1, 12 p., 3914.Research output: Contribution to journal › Journal article › Research › peer-review
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Cabazitaxel as second-line or third-line therapy in patients with metastatic castration-resistant prostate cancer
Kongsted, P., Svane, Inge Marie, Lindberg, H., Bisbjerg, R., Daugaard, G. & Sengeløv, L., Aug 2016, In: Anti-Cancer Drugs. 27, 7, p. 695-701 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cancer immunotherapy in patients with brain metastases
Caponnetto, S., Draghi, A., Borch, T. H., Nuti, M., Cortesi, E., Svane, Inge Marie & dqp123, dqp123, 2018, In: Cancer Immunology, Immunotherapy. 67, 5, p. 703-711 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Cancer immunotherapy in patients with preexisting autoimmune disorders
dqp123, dqp123, Pedersen, M. & Svane, Inge Marie, Apr 2017, In: Seminars in Immunopathology. 39, 3, p. 333-337 5 p.Research output: Contribution to journal › Review › Research › peer-review
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Cancer treatment: the combination of vaccination with other therapies
Andersen, M. H., Sorensen, R. B., Schrama, D., Becker, J. C., Straten, P. T. & Svane, Inge Marie, 2008, In: Cancer Immunology, Immunotherapy. 57, 11, p. 1735-1743 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cancerimmunterapi
Kjeldsen, J. W., dqp123, dqp123 & Svane, Inge Marie, 2018, In: Ugeskrift for Laeger. 180, 5 p., V09170691.Research output: Contribution to journal › Journal article › Research › peer-review
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Cancerimmunterapi til behandling af hæmatologisk cancer
Holmström, M. O., Klausen, U., Jørgensen, N. G., Holmberg, S., Grauslund, J., Met, Ö., Svane, Inge Marie, Pedersen, Lars Møller, Knudsen, L. M., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: Ugeskrift for Laeger. 181, 10, 5 p., V06180421.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiotoxicity in metastatic melanoma patients treated with BRAF and MEK inhibitors in a real-world setting
Pedersen, S., Larsen, K. O., Christensen, Alex Hørby, Svane, Inge Marie, Zerahn, B. & Ellebaek, E., 2022, In: Acta Oncologica. 61, 1, p. 45-51Research output: Contribution to journal › Journal article › Research › peer-review
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Cell culture plastics with immobilized interleukin-4 for monocyte differentiation
Hansen, M., Hjortø, Gertrud Malene, Met, Özcan, Jakobsen, M. H., Svane, Inge Marie & Larsen, N. B., Feb 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell culture plastics with immobilized interleukin-4 for monocyte differentiation
Hansen, M., Hjortø, Gertrud Malene, Met, Ö., Jakobsen, M. H., Svane, Inge Marie & Larsen, N., 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cellular based cancer vaccines: type 1 polarization of dendritic cells
Hansen, M., Met, O., Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cellular based cancer vaccines: type 1 polarization of dendritic cells
Hansen, M., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Changes in peripheral blood level of regulatory T cells in patients with malignant melanoma during treatment with dendritic cell vaccination and low-dose IL-2
Bjoern, J., Brimnes, M. K., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2011, In: Scandinavian Journal of Immunology. 73, 3, p. 222-33 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in the Tumor Immune Microenvironment during Disease Progression in Patients with Ovarian Cancer
Westergaard, M. C. W., Milne, K., Pedersen, M., Hasselager, T., Olsen, L. R., Anglesio, M. S., Borch, T. H., Kennedy, M., Briggs, G., Ledoux, S., Kreuzinger, C., Decken, I. V. D., Donia, M., Castillo-Tong, D. C., Nelson, B. H. & Svane, Inge Marie, 2020, In: Cancers. 12, 12, 19 p., 3828.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization and comparison of "Standard" and "Young" tumor infiltrating lymphocytes for adoptive cell therapy at a Danish Translational Research Institution
Donia, M., Junker, N., Ellebaek, E., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2012, In: Scandinavian Journal of Immunology. 75, 2, p. 157-167 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of Spontaneous Immune Responses against Long Peptides Derived from Bcl-X(L) in Cancer Patients Using Elispot
Svane, Inge Marie, Straten, P. T., Andersen, M. H., Larsen, S. K. & Hansen, M., 2012, In: Cells. 1, 2, p. 51-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of T-cell responses against IκBα in cancer patients
Munir, S., Frøsig, T. M., Hansen, M., Svane, Inge Marie & Andersen, M. H., 2012, In: OncoImmunology. 1, 8, p. 1290-1296 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of a single peptide derived from cytochrome P4501B1 that elicits spontaneous human leukocyte antigen (HLA)-A1 as well as HLA-B35 restricted CD8 T-cell responses in cancer patients
Kvistborg, P., Hadrup, S. R., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2008, In: Human Immunology. 69, 4-5, p. 266-272 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of ex vivo expanded tumor infiltrating lymphocytes from patients with malignant melanoma for clinical application
Junker, N., Thor Straten, P., Andersen, Mads Hald & Svane, Inge Marie, 2011, In: Journal of Skin Cancer. 2011, 574695, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of risk factors and efficacy of medical management of immune-related hepatotoxicity in real-world patients with metastatic melanoma treated with immune checkpoint inhibitors
Romanski, N. A., Holmstroem, R. B., Ellebaek, E. & Svane, Inge Marie, 2020, In: European Journal of Cancer. 130, p. 211-218Research output: Contribution to journal › Journal article › Research › peer-review
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Checkpoint inhibitors in breast cancer - current status
Polk, A., Svane, Inge Marie, Andersson, M. & Nielsen, Dorte Lisbet, 2018, In: Cancer Treatment Reviews. 63, p. 122-134Research output: Contribution to journal › Journal article › Research › peer-review
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Chimeric antigen receptor-T-cellebehandling
Muller, Klaus, Ifversen, M., Kielsen, K., Petersen, S. L., Met, Ö. & Svane, Inge Marie, 2019, In: Ugeskrift for Laeger. 181, 20A, 5 p., V05190309.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical Impact of the Number of Treatment Cycles in First-Line Docetaxel for Patients With Metastatic Castration-Resistant Prostate Cancer
Kongsted, P., Svane, Inge Marie, Lindberg, H. & Sengeløv, L., Apr 2017, In: Clinical Genitourinary Cancer. 15, 2, p. e281-e287Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical advances and ongoing trials on mRNA vaccines for cancer treatment
Lorentzen, C. L., Haanen, J. B., Met, Özcan & Svane, Inge Marie, 2022, In: The Lancet Oncology. 23, 10, p. e450-e458Research output: Contribution to journal › Review › Research › peer-review
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Clinical application of dendritic cells in cancer vaccination therapy
Svane, Inge Marie, Soot, M. L., Buus, Søren & Johnsen, H. E., 2003, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 111, 7-8, p. 818-34 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical efficacy of T-cell therapy after short-term BRAF-inhibitor priming in patients with checkpoint inhibitor-resistant metastatic melanoma
Borch, T. H., Harbst, K., Rana, A. H., Andersen, R., Martinenaite, E., Kongsted, P., Pedersen, M., Nielsen, M., Kjeldsen, J. W., Kverneland, Anders Handrup, Lauss, M., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Met, Özcan, Jönsson, G., dqp123, dqp123 & Svane, Inge Marie, 2021, In: Journal for ImmunoTherapy of Cancer. 9, 7, 15 p., e00270.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
Jespersen, H., Lindberg, M. F., dqp123, dqp123, Söderberg, E. M. V., Andersen, R., Keller, U., Ny, L., Svane, Inge Marie, Nilsson, L. M. & Nilsson, J. A., 2017, In: Nature Communications. 8, 10 p., 707.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical value of routine [18F]2-fluoro-2-deoxy-d-glucose positron emission tomography scans as a decision tool for early immunotherapy discontinuation in advanced melanoma
Ellebaek, E., Schina, A., Andersen, R., Hendel, Helle Westergren, Svane, Inge Marie & dqp123, dqp123, 2022, In: International Journal of Cancer. 150, 11, p. 1870-1878 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Coexisting Alterations of MHC Class I Antigen Presentation and IFNg Signaling Mediate Acquired Resistance of Melanoma to Post-PD-1 Immunotherapy
Nielsen, M., Presti, M., Sztupinszki, Z., Jensen, Agnete Witness Præst, Draghi, A., Chamberlain, C. A., Schina, A., Yde, C. W., Wojcik, J., Szallasi, Z., Crowther, M. D., Svane, Inge Marie & Donia, M., 2022, In: Cancer Immunology Research. 10, 10, p. 1254-1262 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Collagen density regulates the activity of tumor-infiltrating T cells
Kuczek, D. E., Larsen, A. M. H., Thorseth, M., Carretta, M., Kalvisa, A., Siersbæk, M. S., Simões, A. M. C., Roslind, A., Engelholm, Lars Henning, Noessner, E., dqp123, dqp123, Svane, Inge Marie, Straten, P. T., Grøntved, L. & Madsen, D. H., 2019, In: Journal for ImmunoTherapy of Cancer. 7, 1, 15 p., 68.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combination therapy with immune check point inhibitors and acute kidney injury
Valentin, A., Møller, A. K. H., Palshof, J. A., Broberg, B., Gravesen, E., Svane, Inge Marie & Hansen, Ditte, 2023, In: Acta Oncologica. 62, 2, p. 121-125 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined Treatment with Dendritic Cell Vaccine and Low-Dose Cyclophosphamide in Patients with Malignant Melanoma
Engell-Noerregaard, L., Ellebaek, E., Buch-Hansen, T. Z., Nikolajsen, K., Straten, P. T., Andersen, Mads Hald, Svane, Inge Marie & Andersen, Mads Hald, 2010, In: Journal of Immunotherapy. 33, 8, p. 876-877 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Comment on "Adoptive T-cell therapy for malignant melanoma patients with TILs obtained by ultrasound-guided needle biopsy" by Gustav J. Ullenhag et al
Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 5, p. 747; author reply 749Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome
Araujo B de Lima, V., Borch, A., Hansen, M., Draghi, A., Spanggaard, I., Rohrberg, K., Reker Hadrup, S., Lassen, Ulrik Niels & Svane, Inge Marie, Apr 2020, In: Cytotherapy. 22, 4, p. 204-213 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy
Hansen, M., Hjortø, Gertrud Malene, Donia, M., Met, Özcan, Larsen, N. B., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2013, In: Vaccine. 31, 4, p. 639-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of efficacy in patients with metastatic melanoma treated with ipilimumab and nivolumab who did or did not discontinue treatment due to immune-related adverse events: A real-world data study
Fink, M., Vittrup, A. S., Bastholt, L., Svane, Inge Marie, dqp123, dqp123, Luczak, A. A., Ruhlmann, C. H., Guldbrandt, L. M., Koehler, U. H., Winther, M. L., Ellebaek, E., Haslund, C. A. & Schmidt, H., 2021, In: Cancers. 13, 21, 10 p., 5550.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Confinement dependent chemotaxis in two-photon polymerized linear migration constructs with highly definable concentration gradients
Hjortø, Gertrud Malene, Olsen, M. H., Svane, Inge Marie & Larsen, N. B., Apr 2015, In: Biomedical Microdevices. 17, 2, p. 1-10 10 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
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Crossover and rechallenge with pembrolizumab in recurrent patients from the EORTC 1325-MG/Keynote-054 phase III trial, pembrolizumab versus placebo after complete resection of high-risk stage III melanoma
Eggermont, A. M. M., Meshcheryakov, A., Atkinson, V., Blank, C. U., Mandala, M., Long, G. V., Barrow, C., Di Giacomo, A. M., Fisher, R., Sandhu, S., Kudchadkar, R., Romero, P. L. O., Svane, I. M., Larkin, J., Puig, S., Hersey, P., Quaglino, P., Queirolo, P., Stroyakovskiy, D., Bastholt, L. & 14 others, , 2021, In: European Journal of Cancer. 158, p. 156-168 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cutaneous adverse reactions to anti–PD-1 treatment—A systematic review
Simonsen, Anne Birgitte Nørremark, Kaae, Jeanette, Ellebaek, E., Svane, Inge Marie & Zachariae, Claus, 1 Nov 2020, In: Journal of the American Academy of Dermatology. 83, 5, p. 1415-1424 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cytotoxic T cells isolated from healthy donors and cancer patients kill TGFβ-expressing cancer cells in a TGFβ-dependent manner
Holmström, M. O., Mortensen, R. E. J., Pavlidis, A. M., Martinenaite, E., Weis-Banke, S. E., Aaboe-Jørgensen, M., Bendtsen, S. K., Met, Özcan, Pedersen, A. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, Feb 2021, In: Cellular and Molecular Immunology. 18, 2, p. 415-426 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma
Ascierto, P. A., Ferrucci, P. F., Fisher, R., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G. V., Di Giacomo, A. M., Svane, Inge Marie, Lotem, M., Bar-Sela, G., Couture, F., Mookerjee, B., Ghori, R., Ibrahim, N., Moreno, B. H. & Ribas, A., 2019, In: Nature Medicine. 25, 6, p. 941-946 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dendritic Cells Transfected with mRNA for p53, Survivin and hTERT as Treatment for Patients With Malignant Melanoma or Breast Cancer-A Phase I Study
Engell-Noerregaard, L., Hansen, T. H., Met, Ö., Andersen, Mads Hald, Svane, Inge Marie & Andersen, Mads Hald, 2010, In: Journal of Immunotherapy. 33, 8, p. 876 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Dendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II study
Kongsted, P., Borch, T. H., Ellebaek, E., Iversen, T. Z., Andersen, R., Met, Özcan, Hansen, M., Lindberg, H., Sengeløv, L. & Svane, Inge Marie, 1 Apr 2017, In: Cytotherapy. 19, 4, p. 500-513 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients
Iversen, T. Z., Brimnes, M. K., Nikolajsen, K., Andersen, R. S., Hadrup, S. R., Andersen, M. H., Bastholt, L. & Svane, Inge Marie, 2013, In: OncoImmunology. 2, 2, p. 1-10 10 p., e23288.Research output: Contribution to journal › Journal article › Research › peer-review
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Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05
Frøsig, T. M., Yap, J., Seremet, T., Lyngaa, R., Svane, Inge Marie, Thor Straten, P., Heemskerk, M. H. M., Grotenbreg, G. M. & Hadrup, S. R., Oct 2015, In: Cytometry. Part A. 87, 10, p. 967-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab
Kverneland, A. H., Enevold, C., dqp123, dqp123, Bastholt, L., Svane, Inge Marie & Nielsen, C. H., 2018, In: OncoImmunology. 7, 5, p. e1424674 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential effects of corticosteroids and anti-TNF on tumor-specific immune responses: implications for the management of irAEs
Draghi, A., Borch, T. H., Radic, H. D., Chamberlain, C. A., Gokuldass, A., Svane, Inge Marie & dqp123, dqp123, 2019, In: International Journal of Cancer. 145, 5, p. 1408-1413 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, Anders Handrup, Østergaard, Ole, Emdal, Kristina Bennet, Svane, Inge Marie & Olsen, Jesper Velgaard, 2023, In: Proteomics. 23, 7-8, 2200039.Research output: Contribution to journal › Journal article › Research › peer-review
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Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma
Jansen, Y. J. L., Rozeman, E. A., Mason, R., Goldinger, S. M., Geukes Foppen, M. H., Højberg, L., Schmidt, H., van Thienen, J. V., Haanen, J. B. A. G., Tiainen, L., Svane, I. M., Mäkelä, S., Seremet, T., Arance, A., Dummer, R., Bastholt, L., Nyakas, M., Straume, O., Menzies, A. M., Long, G. V. & 3 others, , 2019, In: Annals of Oncology. 30, 7, p. 1154-1161 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissection of T-cell antigen specificity in human melanoma
Andersen, R. S., Albæk Thrue, C., Junker, N., Skou, R. B. L., Donia, M., Ellebæk, E., Svane, Inge Marie, Schumacher, T. N., Thor Straten, P. & Hadrup, S. R., 2012, In: Cancer Research. 72, 7, p. 1642-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Durable clinical responses and long-term follow-up of stage III-IV non-small-cell lung cancer (NSCLC) patients treated with IDO peptide vaccine in a phase i study-a brief research report
Kjeldsen, J. W., Iversen, T. Z., Engell-Noerregaard, L., Mellemgaard, A., Andersen, Mads Hald & Svane, Inge Marie, 2018, In: Frontiers in Immunology. 9, SEP, 6 p., 2145.Research output: Contribution to journal › Journal article › Research › peer-review
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Earlier Recurrence Detection Using Routine FDG PET-CT Scans in Surveillance of Stage IIB to IIID Melanoma: A National Cohort Study of 1480 Patients
Helvind, N. M., Weitemeyer, M. B. M., Chakera, A. H., Hendel, Helle Westergren, Ellebæk, E., Svane, Inge Marie, Kjærskov, M. W., Bojesen, S., Skyum, H., Petersen, S. K., Bastholt, L., Johansen, Christoffer, Bidstrup, P. E. & Hølmich, Lisbet Rosenkrantz, 2023, In: Annals of Surgical Oncology. 30, 4, p. 2377-2388 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Editorial: safety and efficacy of infliximab and corticosteroids in checkpoint inhibitor-induced colitis—authors' reply
Dahl, E. K., Abed, O. K., Kjeldsen, J., dqp123, dqp123, Svane, Inge Marie, Dige, A., Agnholt, J. S., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, Jan 2023, In: Alimentary Pharmacology and Therapeutics. 57, 1, p. 152-153 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Effector and regulatory T cells in patients with acute optic neuritis
Tsakiri, A., Kjærsgaard, E., Grigoriadis, N., Svane, Inge Marie & Frederiksen, J. L., 2012, In: Neuroimmunomodulation. 19, 2, p. 111-20 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis
Dafni, U., Michielin, O., Lluesma, S. M., Tsourti, Z., Polydoropoulou, V., Karlis, D., Besser, M. J., Haanen, J., Svane, Inge Marie, Ohashi, P. S., Kammula, U. S., Orcurto, A., Zimmermann, S., Trueb, L., Klebanoff, C. A., Lotze, M. T., Kandalaft, L. E. & Coukos, G., 2019, In: Annals of Oncology. 30, 12, p. 1902-1913 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip
Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., Apr 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip
Selmeczi, D., Hansen, T., Met, Ö., Svane, Inge Marie & Larsen, N., 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells
Saini, S. K., Tamhane, T., Anjanappa, R., Saikia, A., Ramskov, S., dqp123, dqp123, Svane, Inge Marie, Jakobsen, S. N., Garcia-Alai, M., Zacharias, M., Meijers, R., Springer, S. & Hadrup, S. R., 2019, In: Science immunology. 4, 37, eaau9039.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenetic therapy in combination with a multi-epitope cancer vaccine targeting shared tumor antigens for high-risk myelodysplastic syndrome - a phase I clinical trial
Holmberg-Thydén, S., Dufva, I. H., Gang, Anne Ortved, Breinholt, M. F., Schejbel, L., Andersen, M. K., Kadivar, M., Svane, Inge Marie, Grønbæk, Kirsten, Hadrup, S. R. & El Fassi, D., 2022, In: Cancer Immunology, Immunotherapy. 71, p. 433-444Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity
Litchfield, K., Reading, J. L., Lim, E. L., Xu, H., Liu, P., Al-bakir, M., Wong, Y. N. S., Rowan, A., Funt, S. A., Merghoub, T., Perkins, D., Lauss, M., Svane, Inge Marie, Jönsson, G., Herrero, J., Larkin, J., Quezada, S. A., Hellmann, M. D., Turajlic, S. & Swanton, C., 1 Dec 2020, In: Nature Communications. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of Two Dosing Regimens for Nivolumab in Combination With Ipilimumab in Patients With Advanced Melanoma: Results From the Phase IIIb/IV CheckMate 511 Trial
Lebbé, C., Meyer, N., Mortier, L., Marquez-Rodas, I., Robert, C., Rutkowski, P., Menzies, A. M., Eigentler, T., Ascierto, P. A., Smylie, M., Schadendorf, D., Ajaz, M., Svane, Inge Marie, Gonzalez, R., Rollin, L., Lord-Bessen, J., Saci, A., Grigoryeva, E. & Pigozzo, J., 2019, In: Journal of Clinical Oncology. 37, 11, p. 867-875Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α
Riley, C. H., Hansen, M., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., Straten, P. T., Svane, Inge Marie & Jensen, M. K., Mar 2015, In: European Journal of Haematology. 94, 3, p. 227–234 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FDG PET scans as evaluation of clinical response to dendritic cell vaccination in patients with malignant melanoma
Engell-Noerregaard, L., Hendel, H. W., Johannesen, H. H., Alslev, L. & Svane, Inge Marie, 2013, In: Cancer Immunology, Immunotherapy. 62, 1, p. 17-25 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Feasibility of Intratumoral Anti-PD1 as Treatment of Human Basal Cell Carcinoma: An Explorative Study with Adjuvant Ablative Fractional Laser
Omland, S. H., Ejlertsen, J. S., Krustrup, D., Christensen, R. L., Svane, Inge Marie, Olesen, U. H. & Hædersdal, Merete, 2022, In: Cancers. 14, 23, 5815.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types
Willumsen, N., Jensen, C., Green, G., Nissen, N. I., Neely, J., Nelson, D. M., Pedersen, R. S., Frederiksen, P., Chen, I. M., Boisen, M. K., Johansen, A. Z., Madsen, D. H., Svane, I. M., Lipton, A., Leitzel, K., Ali, S. M., Erler, J. T., Hurkmans, D. P., Mathijssen, R. H. J., Aerts, J. & 5 others, , 2022, In: Cellular and Molecular Life Sciences. 79, 4, 11 p., 204.Research output: Contribution to journal › Review › Research › peer-review
ID: 4054758
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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
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257
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T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
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Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
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