Inge Marie Svane
Clinical Professor
- 2014
- Published
Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway
Ahmad, S. M., Larsen, S. K., Svane, Inge Marie & Andersen, M. H., Jan 2014, In: Leukemia. 28, 1, p. 236-238 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care?
Svane, Inge Marie & Verdegaal, E. M., 2014, In: Cancer immunology, immunotherapy : CII. 63, 10, p. 1081-1091 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
In-chip fabrication of free-form 3D constructs for directed cell migration analysis
Olsen, M. H., Hjortø, Gertrud Malene, Hansen, M., Met, Özcan, Svane, Inge Marie & Larsen, N. B., 21 Dec 2013, In: Lab On a Chip. 13, 24, p. 4800-4809 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional characterization of Foxp3-specific spontaneous immune responses
Larsen, S. K., Munir, S., Woetmann, Anders , Frøsig, T. M., Ødum, Niels, Svane, Inge Marie, Becker, J. C. & Andersen, Mads Hald, Dec 2013, In: Leukemia. 27, 12, p. 2332-40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HLA-Restricted CTL That Are Specific for the Immune Checkpoint Ligand PD-L1 Occur with High Frequency in Cancer Patients
Munir, S., Andersen, G. H., Met, Özcan, Donia, M., Frøsig, T. M., Larsen, S. K., Klausen, T. W., Svane, Inge Marie & Andersen, Mads Hald, 15 Mar 2013, In: Cancer Research. 73, 6, p. 1764-76 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of Survivin-Specific T Cells in Breast Cancer Patients Using Human DCs Engineered with Survivin mRNA
Met, Özcan & Svane, Inge Marie, 2013, Synthetic Messenger RNA and Cell Metabolism Modulation. Vol. 969. p. 275-292 18 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Comparison of clinical grade type 1 polarized and standard matured dendritic cells for cancer immunotherapy
Hansen, M., Hjortø, Gertrud Malene, Donia, M., Met, Özcan, Larsen, N. B., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2013, In: Vaccine. 31, 4, p. 639-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients
Iversen, T. Z., Brimnes, M. K., Nikolajsen, K., Andersen, R. S., Hadrup, S. R., Andersen, M. H., Bastholt, L. & Svane, Inge Marie, 2013, In: OncoImmunology. 2, 2, p. 1-10 10 p., e23288.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FDG PET scans as evaluation of clinical response to dendritic cell vaccination in patients with malignant melanoma
Engell-Noerregaard, L., Hendel, H. W., Johannesen, H. H., Alslev, L. & Svane, Inge Marie, 2013, In: Cancer Immunology, Immunotherapy. 62, 1, p. 17-25 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methods to Improve Adoptive T-Cell Therapy for Melanoma: IFN-γ Enhances Anticancer Responses of Cell Products for Infusion
Donia, M., Hansen, M., Sendrup, S. L., Iversen, T. Z., Ellebæk, E., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2013, In: Journal of Investigative Dermatology. 133, 2, p. 545-52 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Silencing of the glucocorticoid-induced leucine zipper improves the immunogenicity of clinical-grade dendritic cells
Cathelin, D., Met, Özcan & Svane, Inge Marie, 2013, In: Cytotherapy. 15, 6, p. 740-749 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4(+) T cells
Munir, S., Andersen, G. H., Svane, Inge Marie & Andersen, Mads Hald, 2013, In: OncoImmunology. 2, 4, 9 p., e23991.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
A promiscuous survivin-derived T-cell epitope restricted to the HLA-A3 super-type alleles
Junker, N., Munir, S., Kvistborg, P., Straten, P. T., Svane, Inge Marie & Andersen, M. H., 2012, In: Journal of Investigative Dermatology. 132, 8, p. 2115-2118 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients
Ellebaek, E., Iversen, T. Z., Junker, N., Donia, M., Engell-Noerregaard, L., Met, Özcan, Hølmich, Lisbet Rosenkrantz, Andersen, R. S., Hadrup, S. R., Andersen, M. H., Thor Straten, P. & Svane, Inge Marie, 2012, In: Journal of Translational Medicine. 10, p. 169Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes
Donia, M., Ellebaek, E., Andersen, M. H., Straten, P. T. & Svane, Inge Marie, 2012, In: OncoImmunology. 1, 8, p. 1297-1304 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer
Donia, M., Fagone, P., Nicoletti, F., Andersen, R. S., Høgdall, E., Straten, P. T., Andersen, M. H. & Svane, Inge Marie, 2012, In: OncoImmunology. 1, 9, p. 1476-1483 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular based cancer vaccines: type 1 polarization of dendritic cells
Hansen, M., Met, O., Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular based cancer vaccines: type 1 polarization of dendritic cells
Hansen, M., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 2012, In: Current Medicinal Chemistry. 19, 25, p. 4239-46 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Characterization and comparison of "Standard" and "Young" tumor infiltrating lymphocytes for adoptive cell therapy at a Danish Translational Research Institution
Donia, M., Junker, N., Ellebaek, E., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2012, In: Scandinavian Journal of Immunology. 75, 2, p. 157-167 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of Spontaneous Immune Responses against Long Peptides Derived from Bcl-X(L) in Cancer Patients Using Elispot
Svane, Inge Marie, Straten, P. T., Andersen, M. H., Larsen, S. K. & Hansen, M., 2012, In: Cells. 1, 2, p. 51-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of T-cell responses against IκBα in cancer patients
Munir, S., Frøsig, T. M., Hansen, M., Svane, Inge Marie & Andersen, M. H., 2012, In: OncoImmunology. 1, 8, p. 1290-1296 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comment on "Adoptive T-cell therapy for malignant melanoma patients with TILs obtained by ultrasound-guided needle biopsy" by Gustav J. Ullenhag et al
Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 5, p. 747; author reply 749Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissection of T-cell antigen specificity in human melanoma
Andersen, R. S., Albæk Thrue, C., Junker, N., Skou, R. B. L., Donia, M., Ellebæk, E., Svane, Inge Marie, Schumacher, T. N., Thor Straten, P. & Hadrup, S. R., 2012, In: Cancer Research. 72, 7, p. 1642-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effector and regulatory T cells in patients with acute optic neuritis
Tsakiri, A., Kjærsgaard, E., Grigoriadis, N., Svane, Inge Marie & Frederiksen, J. L., 2012, In: Neuroimmunomodulation. 19, 2, p. 111-20 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation of autologous tumor-specific T cells for adoptive transfer based on vaccination, in vitro restimulation and CD3/CD28 dynabead-induced T cell expansion
Brimnes, M. K., Gang, A. O., Donia, M., Thor Straten, P., Svane, Inge Marie & Hadrup, S. R., 2012, In: Cancer Immunology, Immunotherapy. 61, 8, p. 1221-31 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IFN-γ to improve immunotherapy for melanoma
Donia, M., Svane, Inge Marie, Andersen, M. H., Hansen, M., Straten, P. T., Ellebæk, E., Iversen, T. Z. & SL, S., 2012. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Immunotherapy for metastatic colorectal cancer: Present status and new options
Ellebaek, E., Andersen, M. H., Svane, Inge Marie & Straten, P. T., 2012, In: Scandinavian Journal of Gastroenterology. 47, 3, p. 315-24 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial
Ellebaek, E., Engell-Noerregaard, L., Iversen, T. Z., Moerch Froesig, T., Munir, S., Hadrup, S. R., Andersen, M. H. & Svane, Inge Marie, 2012, In: Cancer Immunology, Immunotherapy. 61, 10, p. 1791-1804 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase
Munir, S., Larsen, S. K., Iversen, T. Z., Donia, M., Klausen, T. W., Svane, Inge Marie, Straten, P. T. & Andersen, M. H., 2012, In: P L o S One. 7, 4, p. e34568Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor associated antigen specific T-cell populations identified in ex vivo expanded TIL cultures
Junker, N., Kvistborg, P., Køllgaard, T., Straten, P. T., Andersen, Mads Hald & Svane, Inge Marie, 2012, In: Cellular Immunology. 273, 1, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Increase in circulating CD4CD25Foxp3 T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α
Riley, C. H., Morten Krogh, J., Brimnes, M. K., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Bjerrum, O. W., 25 Aug 2011, In: Blood. 118, 8, p. 2170-2173 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip
Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., Apr 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., Buchwald, C. V., Andersen, E., Straten, P. T., Svane, Inge Marie & Andersen, Mads Hald, 24 Mar 2011, In: Cytotherapy. 13, 7, p. 822-34Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2
Sørensen, R. B., Køllgaard, T., Andersen, R. S., van den Berg, J. H., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 15 Mar 2011, In: Cancer Research. 71, 6, p. 2038-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators
Sørensen, R. B., Hadrup, S. R., Svane, Inge Marie, Hjortsø, M. C., Thor Straten, P., Andersen, Mads Hald, Hjortsø, M. C. & Andersen, Mads Hald, 17 Feb 2011, In: Blood. 117, 7, p. 2200-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell culture plastics with immobilized interleukin-4 for monocyte differentiation
Hansen, M., Hjortø, Gertrud Malene, Met, Özcan, Jakobsen, M. H., Svane, Inge Marie & Larsen, N. B., Feb 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer
Met, Özcan, Balslev, E., Flyger, H. & Svane, Inge Marie, 1 Jan 2011, In: Breast Cancer Research and Treatment. 125, 2, p. 395-406 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bimodal ex vivo expansion of T cells from patients with head and neck squamous cell carcinoma: a prerequisite for adoptive cell transfer
Junker, N., Andersen, Mads Hald, Wenandy, L., Dombernowsky, S. L., Kiss, K., Sørensen, C. H., Therkildsen, M. H., von Buchwald, Christian, Andersen, E., Straten, P. T. & Svane, Inge Marie, 2011, In: Cytotherapy. 13, 7, p. 822-34 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell culture plastics with immobilized interleukin-4 for monocyte differentiation
Hansen, M., Hjortø, Gertrud Malene, Met, Ö., Jakobsen, M. H., Svane, Inge Marie & Larsen, N., 2011, In: Journal of Biomedical Materials Research. Part A. 96, 2, p. 372-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in peripheral blood level of regulatory T cells in patients with malignant melanoma during treatment with dendritic cell vaccination and low-dose IL-2
Bjoern, J., Brimnes, M. K., Andersen, Mads Hald, Straten, P. T. & Svane, Inge Marie, 2011, In: Scandinavian Journal of Immunology. 73, 3, p. 222-33 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of ex vivo expanded tumor infiltrating lymphocytes from patients with malignant melanoma for clinical application
Junker, N., Thor Straten, P., Andersen, Mads Hald & Svane, Inge Marie, 2011, In: Journal of Skin Cancer. 2011, 574695, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient large volume electroporation of dendritic cells through micrometer scale manipulation of flow in a disposable polymer chip
Selmeczi, D., Hansen, T., Met, Ö., Svane, Inge Marie & Larsen, N., 2011, In: Biomedical Microdevices. 13, 2, p. 383-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors
Andersen, R. S., Sørensen, R. B., Ritter, C., Svane, Inge Marie, Becker, J. C., thor Straten, P. & Andersen, Mads Hald, 2011, In: Cancer Immunology, Immunotherapy. 60, 2, p. 227-34 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in circulating CD4⁺CD25⁺Foxp3⁺ T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α
Riley, C. H., Jensen, M. K., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., Straten, P. T. & Svane, Inge Marie, 2011, In: Blood. 118, 8, p. 2170-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Wildtype p53-specific Antibody and T-Cell Responses in Cancer Patients
Pedersen, Anders Elm, Stryhn, A., Justesen, S., Harndahl, M., Rasmussen, S., Donskov, F., Claesson, Mogens Helweg, Pedersen, J. W., Wandall, Hans H., Svane, Inge Marie & Buus, Søren, 2011, In: Journal of Immunotherapy. 34, 9, p. 629-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Increased level of both CD4+FOXP3+ regulatory T cells and CD14+HLA-DR⁻/low myeloid-derived suppressor cells and decreased level of dendritic cells in patients with multiple myeloma
Brimnes, M. K., Vangsted, A. J., Knudsen, L. M., Gimsing, P., Gang, A. O., Johnsen, H. & Svane, Inge Marie, 1 Dec 2010, In: Scandinavian Journal of Immunology. 72, 6, p. 540-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety and clinical effect of subcutaneous human interleukin-21 in patients with metastatic melanoma or renal cell carcinoma: a phase I trial
Schmidt, H., Brown, J., Mouritzen, U., Selby, P., Fode, K., Svane, Inge Marie, Cook, G. P., Mollerup, D. H. & Geertsen, P. F., 1 Nov 2010, In: Clinical Cancer Research. 16, 21, p. 5312-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial
Trepiakas, R., Berntsen, A., Hadrup, S. R., Bjørn, J., Geertsen, P. F., Straten, P. T., Andersen, Mads Hald, Pedersen, Anders Elm, Soleimani, A., Lorentzen, T., Johansen, Julia Sidenius & Svane, Inge Marie, 1 Oct 2010, In: Cytotherapy. 12, 6, p. 721-34 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased immunopotency of monocyte derived dendritic cells from patients with optic neuritis is inhibited in vitro by simvastatin
Tsakiri, A., Tsiantoulas, D., Fredriksen, Jette Lautrup & Svane, Inge Marie, 1 Feb 2010, In: Experimental Neurology. 221, 2, p. 320-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Therapeutic cancer vaccines in combination with conventional therapy
Andersen, Mads Hald, Junker, N., Ellebaek, E., Svane, Inge Marie, Thor Straten, P. & Andersen, Mads Hald, 1 Jan 2010, In: Journal of Biomedicine and Biotechnology. 2010, p. 237623Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4054758
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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
257
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T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
Research output: Contribution to journal › Journal article › Research › peer-review
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189
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Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
Research output: Contribution to journal › Journal article › Research › peer-review
Published