Neurologiske bivirkninger af cancerimmunterapi med checkpointinhibitorer
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Neurologiske bivirkninger af cancerimmunterapi med checkpointinhibitorer. / Stenör, Christian; Ellebæk, Eva; El Mahdaoui, Sahla; Svane, Inge Marie.
In: Ugeskrift for Laeger, Vol. 183, No. 2, V05200406, 11.01.2021.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Neurologiske bivirkninger af cancerimmunterapi med checkpointinhibitorer
AU - Stenör, Christian
AU - Ellebæk, Eva
AU - El Mahdaoui, Sahla
AU - Svane, Inge Marie
PY - 2021/1/11
Y1 - 2021/1/11
N2 - Treatment with checkpoint inhibitors has revolutionised the treatment of many different cancers with a significant improvement in cancer survival. However, a different type of adverse effects is seen compared to standard chemotherapy called immune-related adverse effects (irAE). In this review, we give recommendations on how to diagnose and treat the most common and severe neurologic irAE. We advise clinicians to be cautious to classify neurologic irAE as well-known nosologic entities, since their presentation, cause and treatment often is different.
AB - Treatment with checkpoint inhibitors has revolutionised the treatment of many different cancers with a significant improvement in cancer survival. However, a different type of adverse effects is seen compared to standard chemotherapy called immune-related adverse effects (irAE). In this review, we give recommendations on how to diagnose and treat the most common and severe neurologic irAE. We advise clinicians to be cautious to classify neurologic irAE as well-known nosologic entities, since their presentation, cause and treatment often is different.
KW - Drug-Related Side Effects and Adverse Reactions
KW - Humans
KW - Immunotherapy/adverse effects
KW - Neoplasms/drug therapy
M3 - Tidsskriftartikel
C2 - 33491637
VL - 183
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 2
M1 - V05200406
ER -
ID: 288283903