Hypersensitivity to the diphtheria component in the Di-Te-Pol vaccine. A type I allergic reaction demonstrated by basophil histamine release

Research output: Contribution to journalJournal articleResearchpeer-review

We describe a two year-old multiallergic boy who developed generalized urticaria after the third Di-Te-Pol vaccination. A Type I reaction to the vaccine was demonstrated by performing basophil histamine release to the complete vaccine. Further, we found that the reaction could be exclusively ascribed to Diphtheria-Toxoid whereas no release was observed by the Polio and Tetanus component. The latter result was confirmed since no specific IgE to Tetanus Toxoid could be demonstrated.

Original languageEnglish
JournalPediatric Allergy and Immunology
Volume8
Issue number3
Pages (from-to)156-158
Number of pages3
ISSN0905-6157
DOIs
Publication statusPublished - Aug 1997

    Research areas

  • Allergy, Diphtheria, Histamine release, Hypersensitivity, Polio, Tetanus, Vaccine

ID: 313373241