Eplerenone survival benefits in heart failure patients post-myocardial infarction are independent from its diuretic and potassium-sparing effects. Insights from an EPHESUS (Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study) substudy
Research output: Contribution to journal › Journal article › Research › peer-review
The purpose of this study was to determine whether a diuretic effect may be detectable in patients treated with eplerenone, a mineralocorticoid receptor antagonist, as compared with placebo during the first month of EPHESUS (Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival study) (n = 6,080) and whether this was associated with eplerenone's beneficial effects on cardiovascular outcomes.
| Original language | English |
|---|---|
| Journal | Journal of the American College of Cardiology |
| Volume | 58 |
| Issue number | 19 |
| Pages (from-to) | 1958-66 |
| Number of pages | 9 |
| ISSN | 0735-1097 |
| DOIs | |
| Publication status | Published - 2011 |
ID: 40157341