Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis
Research output: Contribution to journal › Journal article › Research › peer-review
The use of dried blood spots (DBS) samples in genomic workup has been limited by the relative low amounts of genomic DNA (gDNA) they contain. It remains to be proven that whole genome amplified DNA (wgaDNA) from stored DBS samples, constitutes a reliable alternative to gDNA.We wanted to compare melting curves and sequencing results from wgaDNA derived from DBS samples with gDNA derived from whole blood.
| Original language | English |
|---|---|
| Journal | B M C Medical Genetics |
| Volume | 12 |
| Pages (from-to) | 22 |
| ISSN | 1471-2350 |
| DOIs | |
| Publication status | Published - 2011 |
ID: 40218974