Flemming Pociot
Clinical Professor
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Endocrinology
- 2015
- Published
Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987)
Thorsen, S. U., Sandahl, K., Nielsen, L. B., Broe, R., Rasmussen, M. L., Peto, T., Grauslund, J., Andersen, M. L. M., Mortensen, H. B., Pociot, Flemming, Olsen, B. S. & Brorsson, C., Nov 2015, In: Graefe's Archive for Clinical and Experimental Ophthalmology. 253, 11, p. 1959-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study
Witsø, E., Cinek, O., Tapia, G., Brorsson, C. A., Stene, L. C., Gjessing, H. K., Rasmussen, T., Bergholdt, R., Pociot, Flemming & Rønningen, K. S., Dec 2015, In: Viral Immunology. 28, 10, p. 556-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells
Vestergaard, A. L., Blankestijn, M., Stahl, J. L., Pallesen, E. M. H., Bang-Berthelsen, C. H., Pociot, Flemming, Novotny, G. W., Lundh, M. & Mandrup-Poulsen, Thomas, 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 8 p., 896.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control
Brorsson, C. A., Nielsen, L. B., Andersen, M., Kaur, S., Bergholdt, R., Hansen, L., Mortensen, H. B., Pociot, Flemming, Størling, J. & Hvidoere Study Group On Childhood Diabetes, H. S. G. O. C. D., 2016, In: Journal of Diabetes Research. 2016, 8 p., 9570424.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 Diabetes: A 9-Year Nationwide Danish Study
Thorsen, S. U., Pipper, C. B., Mortensen, H. B., Pociot, Flemming, Johannesen, Jesper & Svensson, Jannet, 2016, In: International Journal of Endocrinology. 2016, 7 p., 8350158.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic evaluation of genes and genetic variants associated with type 1 diabetes susceptibility
Ram, R., Mehta, M., Nguyen, T. Q., Larma, I., Boehm, B. O., Pociot, Flemming, Concannon, P. & Morahan, G., 2016, In: Journal of Immunology. 196, 7, p. 3043-3053 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes
Fukaya, M., Brorsson, C. A., Meyerovich, K., Catrysse, L., Delaroche, D., Vanzela, E. C., Ortis, F., Beyaert, R., Nielsen, L. B., Andersen, M. L. M., Mortensen, H. B., Pociot, Flemming, van Loo, G., Størling, J. & Cardozo, A. K., Jan 2016, In: Molecular endocrinology (Baltimore, Md.). 30, 1, p. 48-61 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis
Overgaard, A. J., Weir, J. M., De Souza, D. P., Tull, D., Haase, C., Meikle, P. J. & Pociot, Flemming, Jan 2016, In: Metabolomics. 12, p. 1-9 9 p., 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus
Kaur, S., Mirza, A. H., Brorsson, C. A., Fløyel, T., Størling, Joachim, Mortensen, H. B., Pociot, Flemming & Hvidoere International Study Group, H. I. S. G., 5 Jan 2016, In: Molecular and Cellular Endocrinology. 419, p. 83-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of valid reference genes for microRNA expression studies in a hepatitis B virus replicating liver cell line
Jacobsen, K. S., Nielsen, K. O., Nordmann Winther, T., Glebe, D., Pociot, Flemming & Høgh, Birthe, 22 Jan 2016, In: BMC Research Notes. 9, p. 1-7 7 p., 38.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNAs as regulators of beta-cell function and dysfunction
Osmai, M., Osmai, Y., Bang-Berthelsen, C. H., Pallesen, E. M. H., Vestergaard, A. L., Novotny, G. W., Pociot, Flemming & Mandrup-Poulsen, Thomas, May 2016, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 32, 4, p. 334–349 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk factors for type 1 diabetes
Pociot, Flemming & Lernmark, Å., Jun 2016, In: The Lancet. 387, 10035, p. 2331-9 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of the genome on immune regulation in type 1 diabetes
Pociot, Flemming, Kaur, S. & Nielsen, L. B., Jul 2016, In: Pediatric Diabetes. 17 , S22, p. 37-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential beneficial effects of a gluten-free diet in newly diagnosed children with type 1 diabetes: a pilot study
Svensson, Jannet, Sildorf, S. M., Pipper, C. B., Kyvsgaard, J. N., Bøjstrup, J., Pociot, Flemming, Mortensen, H. B. & Buschard, K., 7 Jul 2016, In: SpringerPlus. 5, 8 p., 994.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Induces Barrier Protective Expression in Brunner's Glands and Regulates Colonic Inflammation
Bang-Berthelsen, C. H., Holm, T. L., Pyke, C., Simonsen, L., Søkilde, R., Pociot, Flemming, Heller, R. S., Folkersen, L., Kvist, P. H., Jackerott, M., Fleckner, J., Vilien, M., Knudsen, L. B., Heding, A. & Frederiksen, K. S., Sep 2016, In: Inflammatory Bowel Diseases. 22, 9, p. 2078-97 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neonatal vitamin D status is not associated with later risk of type 1 diabetes: results from two large Danish population-based studies
Jacobsen, Ramune, Thorsen, S. U., Cohen, A. S., Lundqvist, M., Frederiksen, P., Pipper, C. B., Pociot, Flemming, Thygesen, L. C., Ascherio, A., Svensson, Jannet & Heitmann, Berit, Sep 2016, In: Diabetologia. 59, 9, p. 1871-1881 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolomic Biomarkers in the Progression to Type 1 Diabetes
Overgaard, A. J., Kaur, S. & Pociot, Flemming, Dec 2016, In: Current Diabetes Reports. 16, 5 p., 127.Research output: Contribution to journal › Review › Research › peer-review
- 2017
- Published
Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus
Samandari, N., Mirza, A. H., Nielsen, L. B., Kaur, S., Hougaard, P., Fredheim, S., Mortensen, H. B. & Pociot, Flemming, 2017, In: Diabetologia. 60, 2, p. 354-363Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High neonatal blood iron content is associated with the risk of childhood type 1 diabetes mellitus
Kyvsgaard, J. N., Overgaard, A. J., Thorsen, S. U., Hansen, Thomas Hesselhøj, Pipper, C. B., Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2017, In: Nutrients. 9, 11, 10 p., 1221.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low perinatal zinc status is not associated with the risk of type 1 diabetes in children
Kyvsgaard, J. N., Overgaard, A. J., Jacobsen, L. D., Thorsen, S. U., Pipper, C. B., Hansen, Thomas Hesselhøj, Husted, Søren, Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2017, In: Pediatric Diabetes. 18, 7, p. 637–642 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo
Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts
Kang, W., Bang-Berthelsen, C. H., Holm, A., Houben, A. J. S., Müller, A. H., Thymann, Thomas, Pociot, Flemming, Estivill, X. & Friedländer, M. R., 2017, In: RNA. 23, 4, p. 433-445 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Role of an iNOS Polymorphism at the Post-Diagnosis Diabetes Development in Children with Type 1 Diabetes
Johannesen, J., Eriksen, V., Andersen, M. L. M., Nielsen, L. B., Svensson, Jannet, Bergholdt, R., Pociot, Flemming & Mortensen, H. B., 2017, In: Journal of Endocrinology and Diabetes Research . 2, 2, 5 p., 100114.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The identification and functional annotation of RNA structures conserved in vertebrates
Seemann, Ernst Stefan, Mirza, A. H., Hansen, C., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Torarinsson, E., Yao, Z., Workman, C. T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Genome Research. 27, p. 1371-1383 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study
Thorsen, S. U., Pipper, C. B., Eising, S., Skogstrand, K., Hougaard, D. M., Svensson, Jannet & Pociot, Flemming, Jan 2017, In: Clinical Immunology. 174, p. 18–23 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis
Størling, J. & Pociot, Flemming, 16 Feb 2017, In: Genes. 8, 2, 12 p., 72.Research output: Contribution to journal › Review › Research › peer-review
- Published
Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years
Sandahl, K., Nielsen, L. B., Svensson, Jannet, Johannesen, Jesper, Pociot, Flemming, Mortensen, H. B., Hougaard, P., Broe, R., Rasmussen, M. L., Grauslund, J., Peto, T. & Olsen, B. S., Mar 2017, In: Diabetic Medicine. 34, 3, p. 380–386Research output: Contribution to journal › Journal article › Research › peer-review
- Published
25-Hydroxyvitamin D and Peripheral Immune Mediators: Results from Two Nationwide Danish Pediatric Cohorts
Thorsen, S., Pipper, C., Skogstrand, K., Pociot, Flemming & Svensson, Jannet, Apr 2017, In: Nutrients. 9, 4, 10 p., 365.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long non-coding RNAs as novel players in β cell function and type 1 diabetes
Mirza, A. H., Kaur, S. & Pociot, Flemming, 24 Jul 2017, In: Human Genomics (Online). 11, 10 p., 17.Research output: Contribution to journal › Review › Research › peer-review
- Published
Levels of soluble TREM-1 in children with newly diagnosed type 1 diabetes and their siblings without type 1 diabetes: a Danish case-control study
Thorsen, S. U., Pipper, C. B., Mortensen, H. B., Skogstrand, K., Pociot, Flemming, Johannesen, Jesper, Svensson, Jannet & the Danish Childhood Diabetes Register, T. D. C. D. R., Dec 2017, In: Pediatric Diabetes. 18, 8, p. 749–754Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 1 diabetes genome-wide association studies: Not to be lost in translation
Pociot, Flemming, Dec 2017, In: Clinical and Translational Immunology. 6, 12, 7 p., e162.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
25-hydroxyvitamin D, autoantigenic and total antibody concentrations: Results from a Danish case-control study of newly diagnosed patients with childhood type 1 diabetes and their healthy siblings
Thorsen, S. U., Pipper, C. B., Johannesen, Jesper, Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2018, In: Scandinavian Journal of Immunology. 87, 1, p. 46-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abnormal islet sphingolipid metabolism in type 1 diabetes
Holm, L. J., Krogvold, L., Hasselby, Jane Preuss, Kaur, S., Claessens, L. A., Russell, M. A., Mathews, C. E., Hanssen, K. F., Morgan, N. G., Koeleman, B. P. C., Roep, B. O., Gerling, I. C., Pociot, Flemming, Dahl-Jørgensen, K. & Buschard, K., 2018, In: Diabetologia. 61, 7, p. 1650-1661 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bone Mineral Density Is Increased in 276 Danish Children and Adolescents with Type-1-Diabetes
Madsen, J. O. B., Herskin, C. W., Zerahn, B., Olsen, B. S., Pociot, Flemming & Johannesen, Jesper, 2018, ESPE Abstracts. Bioscientifica, Vol. 89. p. 113 (Hormone Research in Paediatrics).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Cell Type-Selective Expression of Circular RNAs in Human Pancreatic Islets
Kaur, S., Mirza, A. H. & Pociot, Flemming, 2018, In: Non-coding RNA. 4, 4, 20 p., 38.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model
Nielsen, K. O., Jacobsen, K. S., Mirza, A. H., Winther, T. N., Størling, J., Glebe, D., Pociot, Flemming & Høgh, Birthe, 2018, In: Experimental Cell Research. 371, 1, p. 92-103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes
Samandari, N., Mirza, A. H., Kaur, S., Hougaard, P., Nielsen, L. B., Fredheim, S., Mortensen, H. B. & Pociot, Flemming, 2018, In: Non-coding RNA. 4, 4, 12 p., 35.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma lipid species at type 1 diabetes onset predict residual beta-cell function after 6 months
Overgaard, A. J., Weir, J. M., Jayawardana, K., Mortensen, H. B., Pociot, Flemming & Meikle, P. J., 2018, In: Metabolomics. 14, 12, 9 p., 158.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The emerging role of lncrnas in inflammatory bowel disease
Yarani, R., Mirza, A. H., Kaur, S. & Pociot, Flemming, 2018, In: Experimental and Molecular Medicine. 50, p. 1-14 161.Research output: Contribution to journal › Review › Research › peer-review
- Published
miRNAs regulate development and function of regulatory T-cells in recent onset islet autoimmunity in pre-Type 1 diabetes
Kaur, S. & Pociot, Flemming, 2018, In: Non-Coding RNA Investigation. 2, 5 p., 16.Research output: Contribution to journal › Editorial › Research
- Published
Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells
Nielsen, K. O., Mirza, A. H., Kaur, S., Jacobsen, K. S., Winther, T. N., Glebe, D., Pociot, Flemming, Høgh, Birthe & Størling, J., 15 Sep 2018, In: Experimental Cell Research. 370, 2, p. 399-408 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage
Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Association between Neonatal Whole Blood Iron Content and Cytokines, Adipokines, and Other Immune Response Proteins
Thorsen, S. U., Pipper, C. B., Ellervik, Christina, Pociot, Flemming, Kyvsgaard, J. N. & Svensson, Jannet, 2019, In: Nutrients. 11, 3, 12 p., 543.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bone turnover markers in children and adolescents with type 1 diabetes
Madsen, J. O. B., Jørgensen, N. R., Pociot, Flemming & Johannesen, Jesper, 2019, In: Pediatric Diabetes. 20, 5, p. 510-522Research output: Contribution to journal › Review › Research › peer-review
- Published
Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs
Mirza, A. H., Kaur, S., Nielsen, L. B., Størling, J., Yarani, R., Roursgaard, Martin, Mathiesen, Elisabeth, Damm, Peter, Svare, J., Mortensen, H. B. & Pociot, Flemming, 2019, In: Frontiers in Immunology. 10, p. 2543Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capturing residual beta cell function in type 1 diabetes
Pociot, Flemming, 2019, In: Diabetologia. 62, 1, p. 28-32 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining
Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, , 2019, In: eLife. 8, 19 p., e44941.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perinatal Whole Blood Zinc Status and Cytokines, Adipokines, and Other Immune Response Proteins
Kyvsgaard, J. N., Ellervik, Christina, Lindkvist, E. B., Pipper, C. B., Pociot, Flemming, Svensson, Jannet & Thorsen, S. U., 2019, In: Nutrients. 11, 11 p., 1980.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome landscape of protein-coding genes and long noncoding RNAs in the colon and blood of DSS-induced mouse model of Acute ulcerative colitis
Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Litman, Thomas, Holmskov, U., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2019, In: Journal of Crohn's and Colitis. 13, p. S129-S130Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Tu1766 – Dysregulated Lncrnas in Inflammatory Bowel Disease Demonstrate Immune System Related Association Through Guilt-By Association Analysis
Yarani, R., Mirza, A. H., Kaur, S. & Pociot, Flemming, 1 May 2019, In: Gastroenterology. 156, 6, p. S-1116 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 922065
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Transcriptomic landscape of lncRNAs in inflammatory bowel disease
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Plasma proteome analysis of patients with type 1 diabetes with diabetic nephropathy
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Long non-coding RNAs as novel players in β cell function and type 1 diabetes
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