Filip Krag Knop
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Internal Medicine: Endocrinology
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Prognostic factors of 90-day mortality in patients hospitalised with covid-19
Brieghel, C., Ellekvist, P., Lund, M. L., Søborg, C., Walsted, E. S., Thomsen, J. J., Biering-Sørensen, Tor, Mohr, T., Knop, Filip Krag & Ravn, Pernille, 2021, In: Danish Medical Journal. 68, 3, p. 1-9 9 p., A09200705.Research output: Contribution to journal › Journal article › Research › peer-review
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Promising translatable pharmacological interventions for body weight management in individuals with severe mental illness - a narrative review
De, R., Prasad, F., Stogios, N., Burin, L., Ebdrup, Bjørn, Knop, Filip Krag, Hahn, M. K. & Agarwal, S. M., 2023, In: Expert Opinion on Pharmacotherapy. 24, 16, p. 1823-1832 10 p.Research output: Contribution to journal › Review › Research › peer-review
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Protocol for Meal-time Administration of Exenatide for Glycaemic Control in Type 1 Diabetes Cases (The MAG1C trial): A randomised, double-blinded, placebo-controlled trial
Johansen, N. J., Dejgaard, T. F., Lund, A., Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2018, In: BMJ Open. 8, 6, 8 p., 021861.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for a 30-day randomised, parallel-group, non-inferiority, controlled trial investigating the effects of discontinuing renin-angiotensin system inhibitors in patients with and without COVID-19: The RASCOVID-19 trial
Kliim-Hansen, V., Gasbjerg, Lærke Smidt, Ellegaard, A. M., Lorentsson, H. J. N., Lynggaard, M. B., Hagemann, C. A., Legart, C., Mathiesen, D. S., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: BMJ Open. 12, 11, e062895.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for a randomised, double-blinded, placebo-controlled, double-dummy 6-week clinical trial comparing the treatment effects of the glucagon-like peptide 1 receptor agonist liraglutide versus the bile acid sequestrant colesevelam on bile acid malabsorption
Kårhus, M. L., Brønden, A., Forman, Julie Lyng, Haaber, A., Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: BMJ Open. 11, 2, e044711.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Protocol for assessing the effects of exogenous hormone administration on human postprandial glucose metabolism, appetite sensations, and food intake
Hagemann, C. A., Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring & Knop, Filip Krag, 2023, In: STAR Protocols. 4, 1, 10 p., 102070.Research output: Contribution to journal › Journal article › Research › peer-review
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Prototype of an evidence-based tool to aid individualized treatment for type 2 diabetes
Buse, J. B., Holst, I., Knop, Filip Krag, Kvist, K., Thielke, D. & Pratley, R., 2021, In: Diabetes, Obesity and Metabolism. 23, 7, p. 1666-1671Research output: Contribution to journal › Journal article › Research › peer-review
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Psoriasis er associeret med type 2-diabetes
Gyldenl�ve, M., Knop, Filip Krag, Vilsb�ll, T., Zachariae, Claus & Skov, Lone, 4 Mar 2013, In: Ugeskrift for Laeger. 175, 10, p. 652-4 3 p., 652.Research output: Contribution to journal › Journal article › Research › peer-review
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Recovery of gut microbiota of healthy adults following antibiotic exposure
Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, , Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recovery of the incretin effect in type 2 diabetic patients after biliopancreatic diversion
Novaes, F. S., Vasques, A. C. J., Pareja, J. C., Knop, Filip Krag, Tura, A., Chaim, É. A. & Geloneze, B., 1 May 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1984-1988 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recovery of the incretin effect in type 2 diabetic patients after biliopancreatic diversion
Novaes, F. S., Vasques, A. C. J., Pareja, J. C., Knop, Filip Krag, Tura, A., Chaim, É. A. & Geloneze, B., 1 May 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1984-1988 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rectal sensitivity correlated with gastrointestinal-mediated glucose disposal, but not the incretin effect
Meling, S., Tjora, E., Eichele, H., Nedergaard, R. B., Knop, Filip Krag, Ejskjaer, N., Carlsen, S., Njølstad, P. R., Brock, C. & Søfteland, E., 2023, In: Endocrinology, Diabetes and Metabolism. 7, 1, 13 p., e463.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced erythrocyte lifespan measured by chromium-51 in patients with type 2 diabetes undergoing long-term hemodialysis
Bomholt, T., Oturai, P., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Feldt-Rasmussen, Bo & Hornum, M., 2021, In: Hemodialysis International. 25, 2, p. 198-204 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 1 Jul 2010, In: The Journal of clinical endocrinology and metabolism. 95, 7, p. 3309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced postprandial GLP-1 responses in women with gestational diabetes mellitus
Bonde, L., Vilsbøll, Tina, Nielsen, T., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Larsen, S. & Knop, Filip Krag, 13 Feb 2013, In: Diabetes, Obesity and Metabolism. 15, 8, p. 713-720 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of glucagon secretion by incretins
Holst, Jens Juul, Christensen, M., Lund, A., de Heer, J., Svendsen, B., Kielgast, U. & Knop, Filip Krag, Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl 1, p. 89-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Remission of Bile Acid Malabsorption Symptoms Following Treatment With the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide
Kårhus, M. L., Brønden, A., Roder, M. E., Leotta, S., Sonnet, D. P. & Knop, Filip Krag, 2019, In: Gastroenterology. 157, 2, p. 569-571Research output: Contribution to journal › Journal article › Research › peer-review
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Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: challenges and feasibility
Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, T., Jul 2008, In: I Drugs: the Investigational Drugs Journal. 11, 7, p. 497-501 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Resolution of type 2 diabetes following gastric bypass surgery: involvement of gut-derived glucagon and glucagonotropic signalling?
Knop, Filip Krag, 2009, In: Diabetologia. 52, 11, p. 2270-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"
Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.Research output: Contribution to journal › Comment/debate › Research
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Response to letter to the editor from McKee and McGill: “Glycemic control and variability of diabetes secondary to total pancreatectomy assessed by continuous glucose monitoring”
Juel, C. T. B., Dejgaard, T. F., Hansen, C. P., Storkholm, J. H., Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 10, p. E4307-E4308Research output: Contribution to journal › Comment/debate › Research
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Response to the letter: "epidemiologic association between antibiotic use with the risk of developing type 2 diabetes" by López-Hernández, D.
Mikkelsen, K. H., Knop, Filip Krag, Frost, M., Hallas, J. & Pottegard, A., 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 11, 1 p., L121.Research output: Contribution to journal › Letter › Research › peer-review
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Restoration of enteroendocrine and pancreatic function after internal hernia and short bowel syndrome in a young woman with gastric bypass: a 2-year follow-up
Borghede, M., Vinter-Jensen, L., Rasmussen, H. H., Veedfald, Simon, Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Sonne, D. P., 2018, In: Physiological Reports. 6, 9, 6 p., e13686.Research output: Contribution to journal › Journal article › Research › peer-review
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Retinal vascular and structural dynamics during acute hyperglycaemia
Klefter, O. N., Vilsbøll, Tina, Knop, Filip Krag & Larsen, Michael, Dec 2015, In: Acta Ophthalmologica. 93, 8, p. 697-705 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Revisiting the role of glucagon in health, diabetes mellitus and other metabolic diseases
Hædersdal, S., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Nature Reviews Endocrinology. 19, 6, p. 321-335Research output: Contribution to journal › Review › Research › peer-review
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Risk of first-time major cardiovascular event among individuals with newly diagnosed type 2 diabetes: data from Danish registers
Falkentoft, A. C., Gerds, Thomas Alexander, Zareini, B., Knop, Filip Krag, Køber, Lars Valeur, Torp-Pedersen, Christian, Schou, Morten, Bruun, Niels Eske & Ruwald, A. C., 2023, In: Diabetologia. 66, p. 2017–2029 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Risk stratification by endocrinologists of patients with type 2 diabetes in a Danish specialised outpatient clinic: a cross-sectional study
Munch, L., Arreskov, Anne Beiter, Sperling, M., Overgaard, D., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2016, In: BMC Health Services Research. 16, 10 p., 124.Research output: Contribution to journal › Journal article › Research › peer-review
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Safety and Efficacy of Liraglutide in Patients With Type 2 Diabetes and End-Stage Renal Disease: An Investigator-Initiated, Placebo-Controlled, Double-Blinded, Parallel Group, Randomized Trial
Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Feb 2016, In: Diabetes Care. 39, 2, p. 206-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded, parallel intervention study
Idorn, T., Knop, Filip Krag, Jørgensen, M., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 26 Apr 2013, In: B M J Open. 3, 4, p. 1-10 11 p., e002764.Research output: Contribution to journal › Journal article › Research › peer-review
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Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial
Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: A randomised, double-blind, active-comparator, non-inferiority clinical trial
Kårhus, M. L., Brønden, A., Forman, Julie Lyng, Haaber, A., Knudsen, E., Langholz, Ebbe, Dragsted, Lars Ove, Hansen, S. H., Krakauer, M., Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2022, In: The Lancet Gastroenterology and Hepatology. 7, 10, p. 922-931 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Safety of native glucose-dependent insulinotropic polypeptide in humans
Helsted, M. M., Schaltz, N. L., Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Peptides. 177, 14 p., 171214.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies
Calanna, S., Christensen, M., Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2013, In: Diabetologia. 56, 5, p. 965-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies
Calanna, S., Christensen, Mikkel Bring, Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, T. & Knop, Filip Krag, Oct 2013, In: Diabetes Care. 36, 10, p. 3346-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of parathyroid hormone may be coupled to insulin secretion in humans
Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
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Self-expanding metal stents for colonic obstruction: experiences from 104 procedures in a single center
Meisner, S., Hensler, M., Knop, Filip Krag, West, F. & Wille-Jørgensen, P., 1 Apr 2004, In: Diseases of the Colon and Rectum. 47, 4, p. 444-50 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series
Prasad, F., De, R., Korann, V., Chintoh, A. F., Remington, G., Ebdrup, Bjørn, Siskind, D., Knop, Filip Krag, Vilsbøll, Tina, Fink-Jensen, Anders, Hahn, M. K. & Agarwal, S. M., 2023, In: Therapeutic Advances in Psychopharmacology. 13, 10 p., 20451253231165169.Research output: Contribution to journal › Journal article › Research › peer-review
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Semaglutide for the treatment of overweight and obesity: A review
Bergmann, N. C., Davies, M. J., Lingvay, I. & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 1, p. 18-35Research output: Contribution to journal › Review › Research › peer-review
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Semimechanistic model describing gastric emptying and glucose absorption in healthy subjects and patients with type 2 diabetes
Alskär, O., Bagger, J. I., Røge, R. M., Knop, Filip Krag, Karlsson, M. O., Vilsbøll, Tina & Kjellsson, M. C., Mar 2016, In: Journal of Clinical Pharmacology. 56, 3, p. 340-348 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes
Bergmann, N. C., Lund, A., Gasbjerg, Lærke Smidt, Jørgensen, N. R., Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2953–2960Research output: Contribution to journal › Journal article › Research › peer-review
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Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals
Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Jensen, M. H., Gabe, M. B. N., wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2019, In: Diabetes. 68, 3, p. 906-917Research output: Contribution to journal › Journal article › Research › peer-review
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Separate and combined effects of long-term GIP and GLP-1 receptor activation in patients with type 2 diabetes: a structured summary of a study protocol for a double-blind, randomised, placebo-controlled clinical trial
Helsted, M. M., Gasbjerg, Lærke Smidt, Vilsbøll, Tina, Nielsen, C. K., Forman, Julie Lyng, Christensen, Mikkel Bring & Knop, Filip Krag, 2023, In: BMJ Open. 13, 2, 5 p., e065736.Research output: Contribution to journal › Journal article › Research › peer-review
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Serum lipidome unravels a diagnostic potential in bile acid diarrhoea
Lewinska, M., Kårhus, M. L., Ellegaard, A. G., Romero-Gómez, M., Macias, R. I. R., Andersen, Jesper Bøje & Knop, Filip Krag, 2023, In: Gut. 72, 9, p. 1698-1708Research output: Contribution to journal › Journal article › Research › peer-review
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Sevelamer in a diabetologist's perspective: A phosphate-binding resin with glucose-lowering potential
Brønden, Andreas, Hansen, M., Sonne, David Peick, Rohde, U., Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 116-120 5 p.Research output: Contribution to journal › Review › Research › peer-review
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Sevelamer in a diabetologist's perspective: A phosphate-binding resin with glucose-lowering potential
Brønden, Andreas, Hansen, M., Sonne, David Peick, Rohde, U., Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 116-120 5 p.Research output: Contribution to journal › Review › Research › peer-review
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Shared care management of patients with type 2 diabetes across the primary and secondary healthcare sectors: study protocol for a randomised controlled trial
Munch, L., Bennich, B., Arreskov, Anne Beiter, Overgaard, D., Konradsen, H., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2016, In: Trials. 17, 10 p., 277.Research output: Contribution to journal › Journal article › Research › peer-review
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Short-acting glucagon-like peptide-1 receptor agonists as add-on to insulin therapy in type 1 diabetes: A review
Albèr, A., Brønden, A. & Knop, Filip Krag, 2017, In: Diabetes, Obesity and Metabolism. 19, 7, p. 915-925Research output: Contribution to journal › Review › Research › peer-review
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Signs of Glucagon Resistance After a Two-Week Hypercaloric Diet Intervention
Suppli, M. P., Høgedal, A., Bagger, J. I., Chabanova, E., van Hall, Gerrit, Forman, Julie Lyng, Christensen, Mikkel Bring, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 4, p. 955–967 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes
Hartmann, Bolette, Longo, M., Mathiesen, D. S., Hare, Kristine Juul, Jørgensen, Niklas Rye, Esposito, K., Deacon, Carolyn F., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 1, p. e259-e265 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes
Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes
Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Six-day subcutaneous GIP infusion increases glycaemic time in range in patients with type 1 diabetes
Heimbuerger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S73 1 p., 145.Research output: Contribution to journal › Conference abstract in journal › Research
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Small-bowel hemangiosarcoma and capsule endoscopy
Knop, Filip Krag, Hansen, M. B. & Meisner, S., 1 Jul 2003, In: Endoscopy. 35, 7, p. 637Research output: Contribution to journal › Journal article › Research › peer-review
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Sodium-glucose cotransporter (SGLT)-2-inhibitorer til patienter med type 2-diabetes
Røder, M. E., Storgaard, H., Rungby, J., Knop, Filip Krag & Vilsbøll, Tina, 26 Dec 2016, In: Ugeskrift for Laeger. 178, 26, p. 2461-64 V05160310.Research output: Contribution to journal › Journal article › Research › peer-review
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Sodium-glucose cotransporter 2 (SGLT-2) inhibitors for patients with Type 2 diabetes
Røder, M. E., Storgaard, H., Rungby, Jørgen, Knop, Filip Krag & Vilsbøll, Tina, 19 Sep 2016, In: Ugeskrift for Laeger. 178, 38Research output: Contribution to journal › Review › Research › peer-review
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Sodium-glucose cotransporter 2 (SGLT-2) inhibitors for patients with Type 2 diabetes
Røder, M. E., Storgaard, H., Rungby, Jørgen, Knop, Filip Krag & Vilsbøll, Tina, 19 Sep 2016, In: Ugeskrift for Laeger. 178, 38Research output: Contribution to journal › Review › Research › peer-review
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Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors
wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Study protocol for a multicentre, randomised, parallel group, sham-controlled clinical trial investigating the effect of transcutaneous vagal nerve stimulation on gastrointestinal symptoms in people with diabetes complicated with diabetic autonomic neuropathy: The DAN-VNS Study
Okdahl, T., Bertoli, D., Brock, Birgitte, Krogh, K., Knop, Filip Krag, Brock, C. & Drewes, A. M., 2021, In: BMJ Open. 11, 1, e038677.Research output: Contribution to journal › Journal article › Research › peer-review
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Supportive and non-supportive interactions in families with a type 2 diabetes patient: an integrative review
Bennich, B. B., Røder, M. E., Overgaard, D., Egerod, Ingrid Eugenie, Munch, L., Knop, Filip Krag, Vilsbøll, Tina & Konradsen, H., 2017, In: Diabetology & Metabolic Syndrome. 9, 10 p., 57.Research output: Contribution to journal › Review › Research › peer-review
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Sustained heart rate-corrected QT prolongation during recovery from hypoglycaemia in people with type 1 diabetes, independently of recovery to hyperglycaemia or euglycaemia
Andreasen, C. R., Andersen, A., Hagelqvist, P. G., Maytham, K., Lauritsen, J. V., Engberg, S., Faber, Jens, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1566-1575 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sustained weight loss after treatment with a glucagon-like Peptide-1 receptor agonist in an obese patient with schizophrenia and type 2 diabetes
Ishøy, P. L., Knop, Filip Krag, Vilsbøll, Tina, Glenthøj, Birte Yding & Ebdrup, Bjørn, 1 Jun 2013, In: American Journal of Psychiatry. 170, 6, p. 681-682 2 p.Research output: Contribution to journal › Comment/debate › Communication
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Systemic corticosteroids and the risk of venous thromboembolism in patients with severe copd: A nationwide study of 30, 473 outpatients
Rastoder, E., Sivapalan, P., Eklöf, J., Saeed, M. I., Jordan, A. S., Meteran, H., Tønnesen, L., Biering-Sørensen, T., Løkke, A., Seersholm, N., Nielsen, T. L., Carlsen, J., Janner, J., Godtfredsen, N., Bodtger, U., Laursen, C. B., Hilberg, O., Knop, F. K., Priemé, H., Ingebrigtsen, T. S. & 3 others, , 2021, In: Biomedicines. 9, 8, 874.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THERAPY Liraglutide: preventing or postponing T2DM diagnosis?
Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Nature Reviews Endocrinology. 13, p. 320-322Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
THERAPY OF ENDOCRINE DISEASE: Amylin and calcitonin - physiology and pharmacology
Mathiesen, D. S., Lund, A., Holst, Jens Juul, Knop, Filip Krag, Lutz, T. A. & Bagger, J. I., 2022, In: European Journal of Endocrinology. 186, 6, p. R93-R111Research output: Contribution to journal › Review › Research › peer-review
- Published
Targeting the GLP-2 receptor in the management of obesity
Pálsson, T. G., Gilliam-Vigh, Hannah, Jensen, Benjamin Anderschou Holbech, Jeppesen, Palle Bekker, Lund, Asger Bach, Knop, Filip Krag & Nielsen, C. K., 2024, In: Peptides. 177, 9 p., 171210.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Accuracy of Hemoglobin A1c and Fructosamine Evaluated by Long-Term Continuous Glucose Monitoring in Patients with Type 2 Diabetes Undergoing Hemodialysis
Bomholt, T., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Heinrich, N. S., Jørgensen, M. B., Larsson, A., Hilsted, Linda, Feldt-Rasmussen, Bo & Hornum, Mads, 2022, In: Blood Purification. 51, p. 608–616 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Ethanol on Inflammation Markers and FGF-21 in Healthy Individuals
Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Møller, H., Gillum, M., Gronbaek, H., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes. 67, Supplement 1, 2415-PUB.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Epidemiology of Bile Acid Diarrhea in Denmark
Kårhus, M. L., Ellegaard, A. M., Winther-Jensen, M., Hansen, S., Knop, Filip Krag & Kårhus, L. L., 2023, In: Clinical Epidemiology. 15, p. 1173-1181 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Epidemiology of Bile Acid Diarrhea in Denmark [Response to Letter]
Kårhus, M. L., Ellegaard, A. M., Knop, Filip Krag & Kårhus, L. L., 2024, In: Clinical Epidemiology. 16, p. 7-8 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The GLP-1 receptor agonist lixisenatide reduces postprandial glucose in patients with diabetes secondary to total pancreatectomy: a randomised, placebo-controlled, double-blinded crossover trial
Juel, C. T. B., Lund, A., Andersen, M. M., Hansen, C. P., Storkholm, J. H., Rehfeld, Jens Frederik, van Hall, G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2020, In: Diabetologia. 63, p. 1285-1298Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes
Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Glycemic Effect of Liraglutide Evaluated by Continuous Glucose Monitoring in Persons with Type 2 Diabetes Receiving Dialysis
Bomholt, T., Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Ranjan, A. G., Resuli, M., Hansen, P. M., Borg, Rikke, Persson, F., Feldt-Rasmussen, Bo & Hornum, Mads, 2021, In: Nephron. 145, 1, p. 27-34Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Gut: A Key to the Pathogenesis of Type 2 Diabetes?
Holst, Jens Juul, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Knop, Filip Krag, Aug 2017, In: Metabolic Syndrome and Related Disorders. 15, 6, p. 259-262 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Gut-Bone Axis in Diabetes
Maagensen, H., Helsted, M. M., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Current Osteoporosis Reports. 21, p. 21–31 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Liver-Alpha Cell Axis in Health and in Disease
Richter, Michael Martin, Galsgaard, Katrine Douglas, Elmelund, E., Knop, Filip Krag, Suppli, M. P., Holst, Jens Juul, Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes. 71, +, p. 1852–1861Research output: Contribution to journal › Review › Research › peer-review
- Published
The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells
Schisler, J. C., Jensen, P. B., Harper, D. A. T., Becker, T., Knop, Filip Krag, Takekawa, S., German, M., Weir, G. C., Lu, D., Mirmira, R. G. & Newgard, C. B., 17 May 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 20, p. 7297-302 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes
Hædersdal, S., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Mayo Clinic Proceedings. 93, 2, p. 217-239Research output: Contribution to journal › Review › Research › peer-review
- Published
The alpha-cell as target for type 2 diabetes therapy
Christensen, M., Bagger, J. I., Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Review of Diabetic Studies. 8, 3, p. 369-81 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The altered serum lipidome and its diagnostic potential for Non-Alcoholic Fatty Liver (NAFL)-associated hepatocellular carcinoma: Diagnosis of NAFLD-HCC utilising serum lipidomics
Lewinska, M., Santos-Laso, A., Arretxe, E., Alonso, C., Zhuravleva, E., Jimenez-Agüero, R., Eizaguirre, E., Pareja, M. J., Romero-Gómez, M., Jimenez, M. A., Suppli, M. P., Knop, F. K., Oversoe, S. K., Villadsen, G. E., Decaens, T., Carrilho, F. J., de Oliveira, C. PMS., Sangro, B., Macias, R. I. R., Banales, J. M. & 1 others, , 2021, In: EBioMedicine. 73, 103661.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The authors reply
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes
Brønden, A., Albér, A., Rohde, U., Gasbjerg, Lærke Smidt, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetes, Obesity and Metabolism. 20, 2, p. 362-369Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bile-gut axis and metabolic consequences of cholecystectomy
Lange, A. H., Pedersen, M. G., Ellegaard, A. M., Nerild, H. H., Brønden, Andreas, Sonne, David Peick & Knop, Filip Krag, 2024, In: European Journal of Endocrinology. 190, 4, p. R1-R9 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The biology of glucagon and the consequences of hyperglucagonemia
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Pedersen, Jens, Knop, Filip Krag & Holst, Jens Juul, 9 Sep 2016, In: Biomarkers in Medicine. 10, 11, p. 1141-1151 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The design and discovery of lixisenatide for the treatment of type 2 diabetes mellitus
Christensen, M., Miossec, P., Larsen, B. D., Werner, U. & Knop, Filip Krag, 2014, In: Expert Opinion on Drug Discovery. 9, 10, p. 1223-1251 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial
Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial
Foghsgaard, S., Vedtofte, L., Mathiesen, Elisabeth, Svare, J. A., Gluud, Lise Lotte, Holst, Jens Juul, Damm, Peter, Knop, Filip Krag & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of acute intragastric vs. intravenous alcohol administration on inflammation markers, blood lipids and gallbladder motility in healthy men
Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Gillum, M. P., Rehfeld, Jens Frederik, Helsted, M. M., Møller, H. J., Grønbæk, H., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Alcohol. 87, p. 29-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of curcumin on hepatic fat content in individuals with obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of empagliflozin on oxidative nucleic acid modifications in patients with type 2 diabetes: Protocol for a randomised, double-blinded, placebo-controlled trial
Larsen, E. L., Cejvanovic, V., Kjær, L. K., Vilsbøll, Tina, Knop, Filip Krag, Rungby, Jørgen & Poulsen, Henrik Enghusen, May 2017, In: BMJ Open. 7, 5, 6 p., e014728.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity
Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of dual GLP-1/GIP receptor agonism on glucagon secretion: a review
Mathiesen, D. S., Bagger, J. I., Bergmann, N. C., Lund, A., Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: International Journal of Molecular Sciences. 20, 17, 18 p., 4092.Research output: Contribution to journal › Review › Research › peer-review
- Published
The effects of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: protocol for a systematic review with meta-analysis of randomised trials
Storgaard, H., Gluud, Lise Lotte, Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, T., 2014, In: B M J Open. 4, 8, p. 1-5 5 p., e005378.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The efficacy and safety of exenatide once weekly in patients with type 2 diabetes
Heimburger, S. M., Brønden, Andreas, Johansen, N. J., Dejgaard, T. F., Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Expert Opinion on Pharmacotherapy. 20, 5, p. 501-510Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action
Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucose-lowering effect of the bile acid sequestrant sevelamer in patients with type 2 diabetes is not mediated by glucagon-like peptide 1
Nerild, H. H., Brønden, Andreas, Haddouchi, A. E., Holst, Jens Juul, Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 217-217 422.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes
Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of acute fluctuations in plasma glucose on echocardiographic derived measures of systolic function in patients with type 1 diabetes
Andreasen, C. R., Andersen, A., Haqelqvist, P. G., Abelin, K., Lauritsen, J. V., Jorgensen, P. G., Engberg, S., Faber, Jens, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-136 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 40100368
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
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