Flemming Pociot
Clinical Professor
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Endocrinology
- Published
High-Throughput Human Complement C3 N-Glycoprofiling Identifies Markers of Early Onset Type 1 Diabetes Mellitus in Children
Šoić, D., Keser, T., Štambuk, J., Kifer, D., Pociot, Flemming, Lauc, G., Morahan, G., Novokmet, M. & Gornik, O., 2022, In: Molecular and Cellular Proteomics. 21, 10, 100407.Research output: Contribution to journal › Journal article › Research › peer-review
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miRNA-27a-3p and miRNA-222-3p as Novel Modulators of Phosphodiesterase 3a (PDE3A) in Cerebral Microvascular Endothelial Cells
Yasmeen, S., Kaur, S., Mirza, A. H., Larsen, Birger Brodin, Pociot, Flemming & Kruuse, Christina Rostrup, Aug 2019, In: Molecular Neurobiology. 56, 8, p. 5304–5314Research output: Contribution to journal › Journal article › Research › peer-review
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Differentially Expressed miRNAs in Ulcerative Colitis and Crohn's Disease
Yarani, R., Shojaeian, A., Palasca, Oana, Doncheva, Nadezhda Tsankova, Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2022, In: Frontiers in Immunology. 13, 21 p., 865777.Research output: Contribution to journal › Review › Research › peer-review
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The emerging role of lncrnas in inflammatory bowel disease
Yarani, R., Mirza, A. H., Kaur, S. & Pociot, Flemming, 2018, In: Experimental and Molecular Medicine. 50, p. 1-14 161.Research output: Contribution to journal › Review › Research › peer-review
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Tu1766 – Dysregulated Lncrnas in Inflammatory Bowel Disease Demonstrate Immune System Related Association Through Guilt-By Association Analysis
Yarani, R., Mirza, A. H., Kaur, S. & Pociot, Flemming, 1 May 2019, In: Gastroenterology. 156, 6, p. S-1116 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cross-species high-resolution transcriptome profiling suggests biomarkers and therapeutic targets for ulcerative colitis
Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Svane, C. A. S., Mirza, A. H., Litman, Thomas, Holmskov, U., Bang-Berthelsen, C. H., Vilien, M., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2023, In: Frontiers in Molecular Biosciences. 9, 1081176.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptome landscape of protein-coding genes and long noncoding RNAs in the colon and blood of DSS-induced mouse model of Acute ulcerative colitis
Yarani, R., Palasca, Oana, Doncheva, Nadezhda Tsankova, Anthon, Christian, Pilecki, B., Litman, Thomas, Holmskov, U., Jensen, Lars Juhl, Gorodkin, Jan & Pociot, Flemming, 2019, In: Journal of Crohn's and Colitis. 13, p. S129-S130Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study
Witsø, E., Cinek, O., Tapia, G., Brorsson, C. A., Stene, L. C., Gjessing, H. K., Rasmussen, T., Bergholdt, R., Pociot, Flemming & Rønningen, K. S., Dec 2015, In: Viral Immunology. 28, 10, p. 556-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatitis B surface antigen quantity positively correlates with plasma levels of microRNAs differentially expressed in immunological phases of chronic hepatitis B in children
Winther, T. N., Heiberg, I. L., Bang-Berthelsen, C. H., Pociot, Flemming & Høgh, Birthe, 2013, In: PLoS ONE. 8, 11, p. e80384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential plasma microRNA profiles in HBeAg positive and HBeAg negative children with chronic hepatitis B
Winther, T. N., Bang-Berthelsen, C. H., Heiberg, I. L., Pociot, Flemming & Høgh, Birthe, 2013, In: PLOS ONE. 8, 3, p. e58236Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes
Winther, T. N., Jacobsen, K. S., Mirza, A. H., Heiberg, I. L., Bang-Berthelsen, C. H., Pociot, Flemming & Høgh, Birthe, 2014, In: International Journal of Hepatology. 2014, p. 791045Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes
Wegeberg, A. L., Okdahl, T., Fløyel, T., Brock, C., Ejskjaer, N., Riahi, S., Pociot, Flemming, Størling, Joachim & Brock, Birgitte, 2020, In: Mediators of Inflammation. 2020, 10 p., 3590389.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated levels of interleukin-12/23p40 may serve as a potential indicator of dysfunctional heart rate variability in type 2 diabetes
Wegeberg, A. M., Okdahl, T., Riahi, S., Ejskjaer, N., Pociot, Flemming, Størling, Joachim, Brock, Birgitte & Brock, C., 2022, In: Cardiovascular Diabetology. 21, 1, 10 p., 5.Research output: Contribution to journal › Journal article › Research › peer-review
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Selenium supplementation for patients with Graves’ hyperthyroidism (the GRASS trial): study protocol for a randomized controlled trial
Watt, Torquil, Cramon, P., Bjorner, J. B., Bonnema, S. J., Feldt-Rasmussen, Ulla, Gluud, C., Gram, J., Hansen, J. L., Hegedüs, L., Knudsen, Nils Jakob, Bach-Mortensen, P., Nolsöe, R., Nygaard, Birte, Pociot, Flemming, Skoog, M., Winkel, P. & Rasmussen, A. K., 2013, In: Trials. 14, April , p. 1-10 10 p., 119.Research output: Contribution to journal › Journal article › Research › peer-review
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Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex
Viken, M. K., Blomhoff, A., Olsson, M., Akselsen, H. E., Pociot, Flemming, Nerup, J., Kockum, I., Cambon-Thomsen, A., Thorsby, E., Undlien, D. E. & Lie, B. A., 2009, In: Genes and Immunity. 10, 4, p. 323-333 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells
Vestergaard, A. L., Blankestijn, M., Stahl, J. L., Pallesen, E. M. H., Bang-Berthelsen, C. H., Pociot, Flemming, Novotny, G. W., Lundh, M. & Mandrup-Poulsen, Thomas, 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 8 p., 896.Research output: Contribution to journal › Comment/debate › Research › peer-review
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MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage
Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .Research output: Contribution to journal › Journal article › Research › peer-review
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A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study
Thyssen, Jacob Pontoppidan, Linneberg, Allan René, Carlsen, B. C., Johansen, Jeanne Duus, Engkilde, K., Hansen, Torben, Pociot, Flemming, Pedersen, Oluf Borbye, Meldgaard, M., Szecsi, P. B., Stender, Steen & Menné, T., 1 Jan 2011, In: BMJ Open. 1, 1, p. e000062 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between Neonatal Whole Blood Iron Content and Cytokines, Adipokines, and Other Immune Response Proteins
Thorsen, S. U., Pipper, C. B., Ellervik, Christina, Pociot, Flemming, Kyvsgaard, J. N. & Svensson, Jannet, 2019, In: Nutrients. 11, 3, 12 p., 543.Research output: Contribution to journal › Journal article › Research › peer-review
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Levels of soluble TREM-1 in children with newly diagnosed type 1 diabetes and their siblings without type 1 diabetes: a Danish case-control study
Thorsen, S. U., Pipper, C. B., Mortensen, H. B., Skogstrand, K., Pociot, Flemming, Johannesen, Jesper, Svensson, Jannet & the Danish Childhood Diabetes Register, T. D. C. D. R., Dec 2017, In: Pediatric Diabetes. 18, 8, p. 749–754Research output: Contribution to journal › Journal article › Research › peer-review
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No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 Diabetes: A 9-Year Nationwide Danish Study
Thorsen, S. U., Pipper, C. B., Mortensen, H. B., Pociot, Flemming, Johannesen, Jesper & Svensson, Jannet, 2016, In: International Journal of Endocrinology. 2016, 7 p., 8350158.Research output: Contribution to journal › Journal article › Research › peer-review
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Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study
Thorsen, S. U., Pipper, C. B., Eising, S., Skogstrand, K., Hougaard, D. M., Svensson, Jannet & Pociot, Flemming, Jan 2017, In: Clinical Immunology. 174, p. 18–23 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No association between type 1 diabetes and genetic variation in vitamin D metabolism genes: a Danish study
Thorsen, S. U., Mortensen, H. B., Carstensen, Bendix, Fenger, M., Thuesen, B. H., Husemoen, L., Bergholdt, R., Brorsson, C., Pociot, Flemming, Linneberg, Allan René & Svensson, Jannet, Sep 2014, In: Pediatric Diabetes. 15, 6, p. 416-421 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No difference in vitamin d levels between children newly diagnosed with type 1 diabetes and their healthy siblings
Thorsen, S. U., Mortensen, H. B., Carstensen, Bendix, Fenger, M., Thuesen, B. H., Husemoen, L. L., Bergholdt, R., Brorsson, C., Pociot, Flemming, Linneberg, Allan René & Svensson, Jannet, 2013, In: Diabetes Care. 36, 9, p. e157-e158Research output: Contribution to journal › Journal article › Research › peer-review
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Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987)
Thorsen, S. U., Sandahl, K., Nielsen, L. B., Broe, R., Rasmussen, M. L., Peto, T., Grauslund, J., Andersen, M. L. M., Mortensen, H. B., Pociot, Flemming, Olsen, B. S. & Brorsson, C., Nov 2015, In: Graefe's Archive for Clinical and Experimental Ophthalmology. 253, 11, p. 1959-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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25-Hydroxyvitamin D and Peripheral Immune Mediators: Results from Two Nationwide Danish Pediatric Cohorts
Thorsen, S., Pipper, C., Skogstrand, K., Pociot, Flemming & Svensson, Jannet, Apr 2017, In: Nutrients. 9, 4, 10 p., 365.Research output: Contribution to journal › Journal article › Research › peer-review
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25-hydroxyvitamin D, autoantigenic and total antibody concentrations: Results from a Danish case-control study of newly diagnosed patients with childhood type 1 diabetes and their healthy siblings
Thorsen, S. U., Pipper, C. B., Johannesen, Jesper, Mortensen, H. B., Pociot, Flemming & Svensson, Jannet, 2018, In: Scandinavian Journal of Immunology. 87, 1, p. 46-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Systemic levels of CCL2, CCL3, CCL4 and CXCL8 differ according to age, time period and season among children newly diagnosed with type 1 diabetes and their healthy siblings
Thorsen, S. U., Eising, S., Mortensen, H. B., Skogstrand, K., Pociot, Flemming, Johannesen, Jesper, Svensson, Jannet & Danish Childhood Diabetes Registry, D. C. D. R., Dec 2014, In: Scandinavian Journal of Immunology. 80, 6, p. 452-461 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PDE12 in type 1 diabetes
Tekin, H., Josefsen, K., Krogvold, L., Dahl-Jørgensen, K., Gerling, I., Pociot, Flemming & Buschard, K., 2022, In: Scientific Reports. 12, 18149.Research output: Contribution to journal › Journal article › Research › peer-review
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Assisting the implementation of screening for type 1 diabetes by using artificial intelligence on publicly available data
Teixeira, P. F., Battelino, T., Carlsson, A., Gudbjörnsdottir, S., Hannelius, U., von Herrath, M., Knip, M., Korsgren, O., Elding Larsson, H., Lindqvist, A., Ludvigsson, J., Lundgren, M., Nowak, C., Pettersson, P., Pociot, Flemming, Sundberg, F., Åkesson, K., Lernmark, Å. & Forsander, G., 2024, In: Diabetologia. 67, 6, p. 985-994Research output: Contribution to journal › Journal article › Research › peer-review
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Potential beneficial effects of a gluten-free diet in newly diagnosed children with type 1 diabetes: a pilot study
Svensson, Jannet, Sildorf, S. M., Pipper, C. B., Kyvsgaard, J. N., Bøjstrup, J., Pociot, Flemming, Mortensen, H. B. & Buschard, K., 7 Jul 2016, In: SpringerPlus. 5, 8 p., 994.Research output: Contribution to journal › Journal article › Research › peer-review
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Gene expression signature predicts rate of type 1 diabetes progression
Suomi, T., Starskaia, I., Kalim, U. U., Rasool, O., Jaakkola, M. K., Grönroos, T., Välikangas, T., Brorsson, C., Mazzoni, G., Bruggraber, S., Overbergh, L., Dunger, D., Peakman, M., Chmura, P., Brunak, S., Schulte, A. M., Mathieu, C., Knip, M., Lahesmaa, R., Elo, L. L. & 4 others, , 2023, In: EBioMedicine. 92, 18 p., 104625.Research output: Contribution to journal › Journal article › Research › peer-review
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Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis
Størling, J. & Pociot, Flemming, 16 Feb 2017, In: Genes. 8, 2, 12 p., 72.Research output: Contribution to journal › Review › Research › peer-review
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Residual β-cell function and the insulin-like growth factor system in Danish children and adolescents with type 1 diabetes
Sorensen, J. S., Birkebaek, N. H., Bjerre, M., Pociot, Flemming, Kristensen, K., Hoejberg, A. S., Frystyk, J. & Danish Society for Diabetes in Childhood and Adolescence, D. S. F. D. I. C. A. A., Mar 2015, In: The Journal of Clinical Endocrinology & Metabolism. 100, 3, p. 1053-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extracellular Vesicle Therapy for Type 1 Diabetes
Soltani, S., Mansouri, K., Emami Aleagha, M. S., Moasefi, N., Yavari, Niloofar, Shakouri, S. K., Notararigo, S., Shojaeian, A., Pociot, Flemming & Yarani, R., 2022, In: Frontiers in Immunology. 13, 865782.Research output: Contribution to journal › Review › Research › peer-review
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Diabetes complications and extracellular vesicle therapy
Soltani, S., Mansouri, K., Parvaneh, S., Thakor, A. S., Pociot, Flemming & Yarani, R., 2022, In: Reviews in Endocrine and Metabolic Disorders. 23, p. 357–385Research output: Contribution to journal › Review › Research › peer-review
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Does rapid sequence divergence preclude RNA structure conservation in vertebrates?
Seemann, Ernst Stefan, Mirza, A. H., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Workman, C. T., Pociot, Flemming, Tommerup, Niels, Gorodkin, Jan & Ruzzo, W. L., 2022, In: Nucleic Acids Research. 50, 5, p. 2452-2463 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The identification and functional annotation of RNA structures conserved in vertebrates
Seemann, Ernst Stefan, Mirza, A. H., Hansen, C., Bang-Berthelsen, C. H., Garde, C., Christensen-Dalsgaard, M., Torarinsson, E., Yao, Z., Workman, C. T., Pociot, Flemming, Nielsen, Henrik, Tommerup, Niels, Ruzzo, W. L. & Gorodkin, Jan, 2017, In: Genome Research. 27, p. 1371-1383 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years
Sandahl, K., Nielsen, L. B., Svensson, Jannet, Johannesen, Jesper, Pociot, Flemming, Mortensen, H. B., Hougaard, P., Broe, R., Rasmussen, M. L., Grauslund, J., Peto, T. & Olsen, B. S., Mar 2017, In: Diabetic Medicine. 34, 3, p. 380–386Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus
Samandari, N., Mirza, A. H., Nielsen, L. B., Kaur, S., Hougaard, P., Fredheim, S., Mortensen, H. B. & Pociot, Flemming, 2017, In: Diabetologia. 60, 2, p. 354-363Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes
Samandari, N., Mirza, A. H., Kaur, S., Hougaard, P., Nielsen, L. B., Fredheim, S., Mortensen, H. B. & Pociot, Flemming, 2018, In: Non-coding RNA. 4, 4, 12 p., 35.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of saffron supplementation on glycemic parameters: An overview of systematic reviews
Sadigi, B., Yarani, R., Mirghafourvand, M., Travica, N., Yousefi, Z., Shakouri, S. K., Ostadrahimi, A., Mobasseri, M., Pociot, Flemming, Sanaie, S. & Araj-Khodaei, M., 2022, In: Phytotherapy Research. 36, 9, p. 3444-3458 15 p.Research output: Contribution to journal › Review › Research › peer-review
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Children at onset of type 1 diabetes show altered N-glycosylation of plasma proteins and IgG
Rudman, N., Kifer, D., Kaur, S., Simunović, V., Cvetko, A., Pociot, Flemming, Morahan, G. & Gornik, O., 2022, In: Diabetologia. 65, 8, p. 1315-1327 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrated glycomics and genetics analyses reveal a potential role for N-glycosylation of plasma proteins and IgGs, as well as the complement system, in the development of type 1 diabetes
Rudman, N., Kaur, S., Simunović, V., Kifer, D., Šoić, D., Keser, T., Štambuk, T., Klarić, L., Pociot, Flemming, Morahan, G. & Gornik, O., 2023, In: Diabetologia. 66, 6, p. 1071-1083 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes
Robertson, C. C. & Type 1 Diabetes Genetics Consortium, T. 1. D. G. C., 2021, In: Nature Genetics. 53, 7, p. 962-971 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Results of the MHC fine mapping workshop
Rich, S. S., Akolkar, B., Concannon, P., Erlich, H., Hilner, J., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, Flemming & Todd, J. A., 2009, In: Diabetes, Obesity and Metabolism. 11, SUPPL. 1, p. 108-109 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives
Rasouli, H., Yarani, R., Pociot, Flemming & Popović-Djordjević, J., May 2020, In: Pharmacological Research. 155, 15 p., 104723.Research output: Contribution to journal › Review › Research › peer-review
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Systematic evaluation of genes and genetic variants associated with type 1 diabetes susceptibility
Ram, R., Mehta, M., Nguyen, T. Q., Larma, I., Boehm, B. O., Pociot, Flemming, Concannon, P. & Morahan, G., 2016, In: Journal of Immunology. 196, 7, p. 3043-3053 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatially conserved regulatory elements identified within human and mouse Cd247 gene using high-throughput sequencing data from the ENCODE project.
Pundhir, Sachin, Hannibal, T. D., Bang-Berthelsen, C. H., Wegener, A. K., Pociot, Flemming, Holmberg, D. I. & Gorodkin, Jan, 2 May 2014, In: Gene. 545, 1, p. 80-87 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Variation within the PPARG gene is associated with residual beta-cell function and glycemic control in children and adolescents during the first year of clinical type 1 diabetes
Porksen, S., Nielsen, L. B., Mortensen, H. B., Danne, T., Kocova, M., Castano, L., Pociot, Flemming, Hougaard, P., Ekstrom, C. T., Gammeltoft, S., Knip, M. & Hansen, L., 2008, In: Pediatric Diabetes Online. 9, 4, p. 297-302 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 922065
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Transcriptomic landscape of lncRNAs in inflammatory bowel disease
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Plasma proteome analysis of patients with type 1 diabetes with diabetic nephropathy
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Long non-coding RNAs as novel players in β cell function and type 1 diabetes
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