Filip Krag Knop

Filip Krag Knop

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. 2023
  2. Published

    Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility

    Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial

    Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Liraglutide treatment is associated with progression of coronary artery fibrous plaque: a prospective 1-year follow-up study in asymptomatic patients with type 2 diabetes

    Heinsen, L. J., Pararajasingam, G., Andersen, T. R., Auscher, S., Sheta, H. M., Precht, H., Engdam, K. B., Hangaard, J., Lambrechtsen, J., Knop, Filip Krag & Egstrup, K., 2023, In: BMC Cardiovascular Disorders. 23, 1, 8 p., 214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    MRI-Based Quantification of Pan-Alimentary Function and Motility in Subjects with Diabetes and Gastrointestinal Symptoms

    Bertoli, D., Mark, E. B., Liao, D., Okdahl, T., Nauser, S., Daugberg, L. H., Brock, C., Brock, Birgitte, Knop, Filip Krag, Krogh, K., Brøndum Frøkjær, J. & Drewes, A. M., 2023, In: Journal of Clinical Medicine. 12, 18, 16 p., 5968.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Management of dyslipidaemia in individuals with severe mental illness: a population-based study in the Greater Copenhagen Area

    Høgnason Mohr, G., Barcella, C. A., Grand, Mia Klinten, Kriegbaum, Margit, Siersma, Volkert Dirk, Hahn, M. K., Agarwal, S. M., Bakkedal, Catrine, Baandrup, Lone, Knop, Filip Krag, Andersen, C. L. & Ebdrup, Bjørn, 2023, In: Therapeutic Advances in Psychopharmacology. 13, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes and Chronic Kidney Disease

    Adrian, T., Hornum, Mads, Knop, Filip Krag, Almdal, Thomas Peter, Rossing, Peter, Lida, L., Heinrich, N. S., Boer, V. O., Marsman, A., Petersen, E. T., Siebner, Hartwig Roman & Feldt-Rasmussen, Bo, 2023, In: Nephron. 147, 6, p. 317–328

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response

    Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial

    OASIS 1 Investigators, O. 1. I., 2023, In: The Lancet. 402, 10403, p. 705-719 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Pan-alimentary assessment of motility, luminal content, and structures: an MRI-based framework

    Bertoli, D., Mark, E. B., Liao, D., Brock, C., Brock, Birgitte, Knop, Filip Krag, Krogh, K., Frøkjær, J. B. & Drewes, A. M., 2023, In: Scandinavian Journal of Gastroenterology. 58, 12, p. 1378–1390 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Promising translatable pharmacological interventions for body weight management in individuals with severe mental illness - a narrative review

    De, R., Prasad, F., Stogios, N., Burin, L., Ebdrup, Bjørn, Knop, Filip Krag, Hahn, M. K. & Agarwal, S. M., 2023, In: Expert Opinion on Pharmacotherapy. 24, 16, p. 1823-1832 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Protocol for assessing the effects of exogenous hormone administration on human postprandial glucose metabolism, appetite sensations, and food intake

    Hagemann, C. A., Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring & Knop, Filip Krag, 2023, In: STAR Protocols. 4, 1, 10 p., 102070.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Rectal sensitivity correlated with gastrointestinal-mediated glucose disposal, but not the incretin effect

    Meling, S., Tjora, E., Eichele, H., Nedergaard, R. B., Knop, Filip Krag, Ejskjaer, N., Carlsen, S., Njølstad, P. R., Brock, C. & Søfteland, E., 2023, In: Endocrinology, Diabetes and Metabolism. 7, 1, 13 p., e463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Revisiting the role of glucagon in health, diabetes mellitus and other metabolic diseases

    Hædersdal, S., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Nature Reviews Endocrinology. 19, 6, p. 321-335

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Risk of first-time major cardiovascular event among individuals with newly diagnosed type 2 diabetes: data from Danish registers

    Falkentoft, A. C., Gerds, Thomas Alexander, Zareini, B., Knop, Filip Krag, Køber, Lars Valeur, Torp-Pedersen, Christian, Schou, Morten, Bruun, Niels Eske & Ruwald, A. C., 2023, In: Diabetologia. 66, p. 2017–2029 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series

    Prasad, F., De, R., Korann, V., Chintoh, A. F., Remington, G., Ebdrup, Bjørn, Siskind, D., Knop, Filip Krag, Vilsbøll, Tina, Fink-Jensen, Anders, Hahn, M. K. & Agarwal, S. M., 2023, In: Therapeutic Advances in Psychopharmacology. 13, 10 p., 20451253231165169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Semaglutide for the treatment of overweight and obesity: A review

    Bergmann, N. C., Davies, M. J., Lingvay, I. & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 1, p. 18-35

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published
  20. Published

    Serum lipidome unravels a diagnostic potential in bile acid diarrhoea

    Lewinska, M., Kårhus, M. L., Ellegaard, A. G., Romero-Gómez, M., Macias, R. I. R., Andersen, Jesper Bøje & Knop, Filip Krag, 2023, In: Gut. 72, 9, p. 1698-1708

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Sustained heart rate-corrected QT prolongation during recovery from hypoglycaemia in people with type 1 diabetes, independently of recovery to hyperglycaemia or euglycaemia

    Andreasen, C. R., Andersen, A., Hagelqvist, P. G., Maytham, K., Lauritsen, J. V., Engberg, S., Faber, Jens, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1566-1575 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The Epidemiology of Bile Acid Diarrhea in Denmark

    Kårhus, M. L., Ellegaard, A. M., Winther-Jensen, M., Hansen, S., Knop, Filip Krag & Kårhus, L. L., 2023, In: Clinical Epidemiology. 15, p. 1173-1181 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The Gut-Bone Axis in Diabetes

    Maagensen, H., Helsted, M. M., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Current Osteoporosis Reports. 21, p. 21–31 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    The impact of type 2 diabetes and glycaemic control on mortality and clinical outcomes in hospitalized patients with COVID-19 in the capital region of Denmark

    Kliim-Hansen, V., Johansson, K. S., Gasbjerg, Lærke Smidt, Solem, Espen Victor Jimenez, Petersen, Tonny Studsgaard, Nyeland, M. E., Winther-Jensen, M., Ankarfeldt, Mikkel Zöllner, Pedersen, M. G., Ellegaard, A. M., Knop, Filip Krag & Christensen, Mikkel Bring, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 160-168 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The potential of colchicine for lowering the risk of cardiovascular events in type 1 diabetes

    Johansen, N. J. & Knop, Filip Krag, 2023, In: European Heart Journal - Cardiovascular Pharmacotherapy. 9, 4, p. 311-317

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Value of gym-based group exercise versus usual care for young adults receiving antipsychotic medication: study protocol for the multicenter randomized controlled Vega trial

    Rafn, B. S., Andersen, M. F., Sørensen, V., Bjerre, E. D., Baandrup, Lone, Vernal, D. L., Mors, O., Knop, Filip Krag, Wolf, R. T., Tolver, Anders, Firth, J., Nøhr, N., Skou, S. T., Ebdrup, Bjørn & Midtgaard, Julie, 2023, In: BMC Psychiatry. 23, 1, 13 p., 634.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Why diversity among participants in clinical studies is not always preferable: the case for small, exploratory studies

    Ellegaard, A. M. & Knop, Filip Krag, 2023, In: BMC Medicine. 21, 1, 3 p., 462.

    Research output: Contribution to journalComment/debateResearchpeer-review

  30. 2022
  31. Published

    MYC mRNA expression throughout the intestine is not associated with body mass index or type 2 diabetes

    Ellegaard, A. & Knop, Filip Krag, 2022, In: Endocrinology, Diabetes and Metabolism. 5, 2, 4 p., 00327.

    Research output: Contribution to journalComment/debateResearch

  32. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity

    Hagemann, C. A., Legart, C., Møllerhøj, M. B., Madsen, M. R., Hansen, H. H., Kønig, M. J., Helgstrand, Frederik, Hjørne, F. P., Toxværd, A., Langhoff, J. L., Kielgast, U. L., Gluud, Lise Lotte, Ægidius, H., Rigbolt, K. T. G., Vilsbøll, Tina, Jelsing, J. & Knop, Filip Krag, 2022, In: PLoS ONE. 17, 10, 19 p., e0275901.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls

    Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, Mikkel Bring, Pedersen-Bjergaard, Ulrik, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1123-1131

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published

    Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial

    Sivapalan, P. & ProPAC-COVID writing group on behalf of the ProPAC-COVID Study Group, P. W. G. O. B. O. T. P. S. G., 2022, In: European Respiratory Journal. 59, 1, 2100752.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2

    Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial

    Hvistendahl, M. K., Naimi, R. M., Hansen, S. H., Rehfeld, Jens Frederik, Kissow, Hannelouise, Pedersen, Jens, Dragsted, Lars Ove, Sonne, D. P., Knop, Filip Krag & Jeppesen, Palle Bekker, 2022, In: Journal of Parenteral and Enteral Nutrition. 46, 4, p. 923-935 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

    Nielsen, C. K., Øhrstrøm, C. C., Kielgast, U. L., Hansen, D. L., Hartmann, Bolette, Holst, Jens Juul, Lund, Asger Bach, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes Care. 45, 6, p. 1476–1481

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Dyslipidæmi ved psykisk lidelse

    Mohr, G. H., Barcella, C. A., Coello, K., Baandrup, Lone & Knop, Filip Krag, 2022, In: Ugeskrift for Laeger. 184, 10, 10 p., V05210439.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Effects of short-acting exenatide added three times daily to insulin therapy on bone metabolism in type 1 diabetes

    Johansen, N. J., Dejgaard, T. F., Lund, A., Schlüntz, Camilla, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 221-227

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published
  43. Published

    Enterohepatic, gluco-metabolic, and gut microbial characterization of individuals with bile acid malabsorption

    Kårhus, M. L., Sonne, David Peick, Thomasen, M., Ellegaard, A., Holst, Jens Juul, Rehfeld, Jens Frederik, Chávez-Talavera, O., Tailleux, A., Staels, B., Nielsen, Dennis Sandris, Dragsted, Lars Ove, Vilsbøll, Tina, Brønden, A. & Knop, Filip Krag, 2022, In: Gastro Hep Advances. 1, 3, p. 299-312 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit

    Flippo, K. H., Trammell, Sam, Gillum, M. P., Aklan, I., Perez, M. B., Yavuz, Y., Smith, N. K., Jensen-Cody, S. O., Zhou, B., Claflin, K. E., Beierschmitt, A., Fink-Jensen, Anders, Knop, Filip Krag, Palmour, R. M., Grueter, B. A., Atasoy, D. & Potthoff, M. J., 2022, In: Cell Metabolism. 34, 2, p. 317-328.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Fibroblast growth factor 21 is the main alcohol responsive peptide hormone in humans and individuals with alcohol use disorder exihibit increased plasma concentrations after alcohol intake

    Lanng, A., Gasbjerg, Lærke Smidt, Sucksdorff, A., Svenningsen, J., Trammell, Sam, Vilsbøll, Tina, Gillum, M. & Knop, Filip Krag, 2022, In: Journal of Hepatology. 77, S1, p. S121-S121 1 p., THU006.

    Research output: Contribution to journalConference abstract in journalResearch

  46. Published

    GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Gastric Aspiration Improves Postprandial Glucose Tolerance Without Causing a Compensatory Increase in Appetite and Food Intake

    Gether, I. M., Jensen, M. M., Nexøe-Larsen, C. C., Jorsal, T., Gasbjerg, Lærke Smidt, Naver, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Obesity Surgery. 32, p. 1385–1390

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Glucagon Clearance is Preserved in Type 2 Diabetes

    Grøndahl, M. F. G., Lund, A., Bagger, J. I., Petersen, Tonny Studsgaard, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 1, db210024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glucose-dependent insulinotropic polypeptide (GIP) induces lipolysis during stable basal insulin substitution and hyperglycemia in men with type 1 diabetes: a randomized, double-blind, placebo-controlled, crossover clinical trial

    Heimburger, S. M., Nielsen, C. N., Calanna, S., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Christensen, Mikkel Bring, 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 142-147

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Glukagonlignende peptid 1-receptoragonister til behandling af type 2-diabetes

    Andersen, A., Christensen, A. S., Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Ugeskrift for Laeger. 181, 2, V10180725.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Hemoglobin A1c and Fructosamine Evaluated in Patients with Type 2 Diabetes Receiving Peritoneal Dialysis Using Long-Term Continuous Glucose Monitoring

    Bomholt, T., Feldt-Rasmussen, Bo, Butt, Rizwan Ahmed, Borg, Rikke, Sarwary, M. H., Elung-Jensen, T., Almdal, Thomas Peter, Knop, Filip Krag, Nørgaard, Kirsten, Ranjan, A. G., Larsson, A., Rix, M. & Hornum, Mads, 2022, In: Nephron. 146, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Hypoglycaemia and rebound hyperglycaemia increase left ventricular systolic function in patients with type 1 diabetes

    Andreasen, C. R., Andersen, A., Hagelqvist, P. G., Lauritsen, J. V., Jørgensen, P. G., Engberg, S., Faber, Jens, Hartmann, Bolette, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2027-2037

    Research output: Contribution to journalJournal articleResearchpeer-review

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