An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight

Research output: Contribution to journal › Review › Research › peer-review

Standard

An overview of obesity mechanisms in humans : Endocrine regulation of food intake, eating behaviour and common determinants of body weight. / Theilade, Simone; Christensen, Mikkel B.; Vilsbøll, Tina; Knop, Filip K.

In: Diabetes, Obesity and Metabolism, Vol. 23, No. S1, 2021, p. 17-35.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Theilade, S, Christensen, MB, Vilsbøll, T & Knop, FK 2021, 'An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight', Diabetes, Obesity and Metabolism, vol. 23, no. S1, pp. 17-35. https://doi.org/10.1111/dom.14270

APA

Theilade, S., Christensen, M. B., Vilsbøll, T., & Knop, F. K. (2021). An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight. Diabetes, Obesity and Metabolism, 23(S1), 17-35. https://doi.org/10.1111/dom.14270

Vancouver

Theilade S, Christensen MB, Vilsbøll T, Knop FK. An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight. Diabetes, Obesity and Metabolism. 2021;23(S1):17-35. https://doi.org/10.1111/dom.14270

Author

Theilade, Simone ; Christensen, Mikkel B. ; Vilsbøll, Tina ; Knop, Filip K. / An overview of obesity mechanisms in humans : Endocrine regulation of food intake, eating behaviour and common determinants of body weight. In: Diabetes, Obesity and Metabolism. 2021 ; Vol. 23, No. S1. pp. 17-35.

Bibtex

@article{120ad4e9b1094b34ae4ecdfa5d3ba769,
title = "An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight",
abstract = "Obesity is one of the biggest health challenges of the 21st century, already affecting close to 700 million people worldwide, debilitating and shortening lives and costing billions of pounds in healthcare costs and loss of workability. Body weight homeostasis relies on complex biological mechanisms and the development of obesity occurs on a background of genetic susceptibility and an environment promoting increased caloric intake and reduced physical activity. The pathophysiology of common obesity links neuro-endocrine and metabolic disturbances with behavioural changes, genetics, epigenetics and cultural habits. Also, specific causes of obesity exist, including monogenetic diseases and iatrogenic causes. In this review, we provide an overview of obesity mechanisms in humans with a focus on energy homeostasis, endocrine regulation of food intake and eating behavior, as well as the most common specific causes of obesity.",
keywords = "appetite control, energy regulation, obesity therapy",
author = "Simone Theilade and Christensen, {Mikkel B.} and Tina Vilsb{\o}ll and Knop, {Filip K.}",
note = "Supplement: OBESITY AS A LIFE‐THREATENING DISEASE: The Importance of Individualized Patient Assessments & Evidence‐based Interventions to Improve Outcomes",
year = "2021",
doi = "10.1111/dom.14270",
language = "English",
volume = "23",
pages = "17--35",
journal = "Diabetes, Obesity and Metabolism",
issn = "1462-8902",
publisher = "Wiley-Blackwell",
number = "S1",

}

RIS

TY - JOUR

T1 - An overview of obesity mechanisms in humans

T2 - Endocrine regulation of food intake, eating behaviour and common determinants of body weight

AU - Theilade, Simone

AU - Christensen, Mikkel B.

AU - Vilsbøll, Tina

AU - Knop, Filip K.

N1 - Supplement: OBESITY AS A LIFE‐THREATENING DISEASE: The Importance of Individualized Patient Assessments & Evidence‐based Interventions to Improve Outcomes

PY - 2021

Y1 - 2021

N2 - Obesity is one of the biggest health challenges of the 21st century, already affecting close to 700 million people worldwide, debilitating and shortening lives and costing billions of pounds in healthcare costs and loss of workability. Body weight homeostasis relies on complex biological mechanisms and the development of obesity occurs on a background of genetic susceptibility and an environment promoting increased caloric intake and reduced physical activity. The pathophysiology of common obesity links neuro-endocrine and metabolic disturbances with behavioural changes, genetics, epigenetics and cultural habits. Also, specific causes of obesity exist, including monogenetic diseases and iatrogenic causes. In this review, we provide an overview of obesity mechanisms in humans with a focus on energy homeostasis, endocrine regulation of food intake and eating behavior, as well as the most common specific causes of obesity.

AB - Obesity is one of the biggest health challenges of the 21st century, already affecting close to 700 million people worldwide, debilitating and shortening lives and costing billions of pounds in healthcare costs and loss of workability. Body weight homeostasis relies on complex biological mechanisms and the development of obesity occurs on a background of genetic susceptibility and an environment promoting increased caloric intake and reduced physical activity. The pathophysiology of common obesity links neuro-endocrine and metabolic disturbances with behavioural changes, genetics, epigenetics and cultural habits. Also, specific causes of obesity exist, including monogenetic diseases and iatrogenic causes. In this review, we provide an overview of obesity mechanisms in humans with a focus on energy homeostasis, endocrine regulation of food intake and eating behavior, as well as the most common specific causes of obesity.

KW - appetite control

KW - energy regulation

KW - obesity therapy

U2 - 10.1111/dom.14270

DO - 10.1111/dom.14270

M3 - Review

C2 - 33621414

VL - 23

SP - 17

EP - 35

JO - Diabetes, Obesity and Metabolism

JF - Diabetes, Obesity and Metabolism

SN - 1462-8902

IS - S1

ER -

ID: 257653591