Jakob Benedict Seidelin

Jakob Benedict Seidelin

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology

ORCID: 0000-0003-3230-7966

Publication year:
All
51 - 75 out of 117Page size: 25
  1. 2015
  2. Published

    IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis

    Seidelin, Jakob Benedict, Coskun, M., Kvist, P. H., Holm, T. L., Holgersen, Kristine & Nielsen, Ole Haagen, Feb 2015, In: Journal of Gastroenterology. 50, 2, p. 180-190 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Species-specific engagement of human nucleotide oligomerization domain 2 (NOD)2 and Toll-like receptor (TLR) signalling upon intracellular bacterial infection: role of Crohn's associated NOD2 gene variants

    Salem, M., Seidelin, Jakob Benedict, Eickhardt-Dalbøge, S. R., Alhede, M., Rogler, G. & Nielsen, Ole Haagen, Mar 2015, In: Clinical and Experimental Immunology. 179, 3, p. 426-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    ATG16L1: A multifunctional susceptibility factor in Crohn disease

    Salem, M., Ammitzboell, M., Nys, K., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 3 Apr 2015, In: Autophagy. 11, 4, p. 585-94 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Alpha-1 antitrypsin and granulocyte colony-stimulating factor as serum biomarkers of disease severity in ulcerative colitis

    Soendergaard, C., Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Kvist, P. H. & Bjerrum, J. T., May 2015, In: Inflammatory Bowel Diseases. 21, 5, p. 1077-88 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    GM6001 Increases Anastomotic Leakage following Colonic Obstruction Possibly by Impeding Epithelialization

    Rehn, M., Krarup, P., Christensen, L. H., Seidelin, Jakob Benedict, Ågren, Magnus & Syk, I., Nov 2015, In: Surgical Infections. 16, 6, p. 702-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease

    Salem, M., Nielsen, Ole Haagen, Nys, K., Yazdanyar, S. & Seidelin, Jakob Benedict, Nov 2015, In: Clinical and Translational Gastroenterology. 6, 9 p., e122.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2016
  9. Published

    Will novel oral formulations change the management of inflammatory bowel disease?

    Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Ainsworth, M. A. & Coskun, M., 2016, In: Expert Opinion on Investigational Drugs. 25, 6, p. 709-718 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes

    Søndergaard, C., Kvist, P. H., Seidelin, Jakob Benedict, Pelzer, H. & Nielsen, Ole Haagen, Aug 2016, In: Journal of Gastroenterology. 51, 8, p. 796-807 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2017
  12. Published

    Asymptomatic carriers contribute to nosocomial Clostridium difficile infection: a cohort study of 4508 patients

    Blixt, T., Gradel, K. O., Homann, C., Seidelin, Jakob Benedict, Schønning, Kristian, Lester, A., Houlind, J., Stangerup, M., Gottlieb, M. & Knudsen, J. D., 2017, In: Gastroenterology. 152, 5, p. 1031-1041.e2

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

    Holmberg, F. E., Seidelin, Jakob Benedict, Yin, X., Mead, B. E., Tong, Z., Li, Yuan, Karp, J. M. & Nielsen, Ole Haagen, 2017, In: EMBO Molecular Medicine. 9, 5, p. 558-570 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels

    Chen, Y., Salem, M., Boyd, M., Lange, Jette Bornholdt, Li, Yuan, Coskun, M., Seidelin, Jakob Benedict, Sandelin, Albin Gustav & Nielsen, Ole Haagen, 2017, In: npj Genomic Medicine. 2, 11 p., 3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Primary monocytes derived from ulcerative colitis show no difference in the TNF-alpha-induced immune response among responders and primary non-responders to infliximab

    Li, Y., Jensen, Kim Bak, Seidelin, Jakob Benedict & Nielsen, O. H., Sep 2017, In: Journal of Gastroenterology and Hepatology. 32, S3, p. 138-138 P-0750.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  16. 2018
  17. Published

    COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

    Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

    Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, P., Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Sandelin, Albin Gustav, 2018, In: Nature Communications. 9, 19 p., 1661.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD

    Soendergaard, C., Seidelin, Jakob Benedict, Steenholdt, C. & Nielsen, Ole Haagen, 2018, In: B M J Open Gastroenterology. 5, 1, e000208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2019
  21. Published

    Exposome and Diet

    Seidelin, Jakob Benedict & Burisch, J., 2019, Biomarkers in Inflammatory Bowel Diseases. Sheng Ding, N. & De Cruz, P. (eds.). Springer, p. 281-291 Chapter 23

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. Published

    Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy

    Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2020
  24. Published

    A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue

    Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, Lene Buhl, Heulot, M., Touati, J., Seidelin, Jakob Benedict, Rizzi, S. C. & Nielsen, Ole Haagen, 2020, In: Biomaterials. 262, 11 p., 120248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Crohn's disease with progressive renal impairment

    Seidelin, Jakob Benedict, Riis, Lene Buhl & Butt, Rizwan Ahmed, 2020, In: Gastroenterology. 158, 1, p. 58-59 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  26. Published

    Predictors of response and disease course in patients with inflammatory bowel disease treated with biological therapy - The Danish IBD Biobank Project: protocol for a multicentre prospective cohort study

    Zhao, M., Bendtsen, Flemming, Petersen, Andreas Munk, Larsen, L., Dige, A., Hvas, C., Seidelin, Jakob Benedict & Burisch, J., 2020, In: BMJ Open. 10, 2, 7 p., e035756.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases

    Jensen, S., Seidelin, Jakob Benedict, LaCasse, E. C. & Nielsen, Ole Haagen, 2020, In: Science Signaling. 13, 619, 18 p., eaax8295.

    Research output: Contribution to journal › Review › Research › peer-review

  28. 2021
  29. Published

    Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans

    Seidelin, Jakob Benedict, Bahl, M. I., Licht, T. R., Mead, B. E., Karp, J. M., Johansen, Jens Vilstrup, Riis, Lene Buhl, Ramírez Galera, Marina, Woetmann, Anders & Bjerrum, Jakob Tveiten , 2021, In: Cellular and Molecular Gastroenterology and Hepatology. 12, 4, p. 1281-1296

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Association between 5-aminosalicylates in patients with IBD and risk of severe COVID-19: an artefactual result of research methodology?

    Attauabi, M. & Danish COVID-IBD Study Group, D. C. S. G., 2021, In: Gut. 70, 10, p. 2020-2022

    Research output: Contribution to journal › Letter › Research › peer-review

  31. Published

    CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T)

    Larsen, S., Seidelin, Jakob Benedict, Davidsen, J., Dahlgaard, K., Nielsen, Claus Henrik, Bennett, Eric Paul, Pedersen, O. B., Coskun, M. & Troelsen, J. T., 2021, In: FEBS Open Bio. 11, 6, p. 1638-1644

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Effectiveness of third-class biologic treatment in crohn’s disease: A multi-center retrospective cohort study

    Albshesh, A., Taylor, J., Savarino, E. V., Truyens, M., Armuzzi, A., Ribaldone, D. G., Shitrit, A. B. G., Fibelman, M., Molander, P., Liefferinckx, C., Nancey, S., Korani, M., Rutka, M., Acosta, M. B. D., Domislovic, V., Suris, G., Eriksson, C., Alves, C., Mpitouli, A., Di Jiang, C. & 26 others, Tepeš, K., Coletta, M., Foteinogiannopoulou, K., Gisbert, J. P., Amir-Barak, H., Attauabi, M., Seidelin, Jakob Benedict, Afif, W., Marinelli, C., Lobaton, T., Pugliese, D., Maharshak, N., Cremer, A., Limdi, J. K., Molnár, T., Otero-Alvarin, B., Krznaric, Z., Magro, F., Karmiris, K., Raine, T., Drobne, D., Koutroubakis, I., Chaparro, M., Yanai, H., Burisch, J. & Kopylov, U., 2021, In: Journal of Clinical Medicine. 10, 13, 2914.

    Research output: Contribution to journal › Journal article › Research › peer-review

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