Jakob Benedict Seidelin

Jakob Benedict Seidelin

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology

ORCID: 0000-0003-3230-7966

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  1. Published

    pcaGoPromoter--an R package for biological and regulatory interpretation of principal components in genome-wide gene expression data

    Hansen, M., Gerds, Thomas Alexander, Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Troelsen, J. T. & Olsen, Jørgen, 2012, In: P L o S One. 7, 2, p. e32394

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis

    Coskun, M., Bjerrum, Jakob Tveiten , Seidelin, Jakob Benedict, Troelsen, J., Olsen, Jørgen & Nielsen, Ole Haagen, 21 Jul 2013, In: World Journal of Gastroenterology. 19, 27, p. 4289-99 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Will novel oral formulations change the management of inflammatory bowel disease?

    Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Ainsworth, M. A. & Coskun, M., 2016, In: Expert Opinion on Investigational Drugs. 25, 6, p. 709-718 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Visioner for medicinsk og uddannelsesmaessig brug af den personlige digitale assistent

    Seidelin, Jakob Benedict & Bech, J., 1 Nov 2004, In: Ugeskrift for Laeger. 166, 45, p. 4019

    Research output: Contribution to journal › Journal article › Research

  5. Published

    Vedolizumab as the first line of biologic therapy for ulcerative colitis and Crohn's disease – a systematic review with meta-analysis

    Attauabi, M., Madsen, G. R., Bendtsen, Flemming, Seidelin, Jakob Benedict & Burisch, J., 2022, In: Digestive and Liver Disease. 54, 9, p. 1168-1178

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Vedolizumab as first-line biological therapy in elderly patients and those with contraindications for anti-TNF therapy: a real-world, nationwide cohort of patients with inflammatory bowel diseases

    Attauabi, M., Höglund, C., Fassov, J., Pedersen, K. B., Hansen, H. B., Wildt, S., Jensen, M. D., Neumann, A., Lind, C., Jacobsen, H. A., Popa, A. M., Kjeldsen, J., Pedersen, N., Molazahi, A., Haderslev, K., Aalykke, C., Knudsen, T., Cebula, W., Munkholm, P., Bendtsen, F. & 2 others, Seidelin, Jakob Benedict & Burisch, J., 2021, In: Scandinavian Journal of Gastroenterology. 56, 9, p. 1040-1048

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Use of biological molecules in the treatment of inflammatory bowel disease

    Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Munck, Lars Kristian & Rogler, G., Jul 2011, In: Journal of Internal Medicine. 270, 1, p. 15-28 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Upregulation of cIAP2 in regenerating colonocytes in ulcerative colitis

    Seidelin, Jakob Benedict, Vainer, B., Andresen, Lars & Nielsen, Ole Haagen, 2007, In: Virchows Archiv. 451, 6, p. 1031-1038 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Unraveling the Place of Small Molecules in theTreatment of Fistulizing Crohn’s Disease—A Systematic Review and Network Meta-Analysis

    Attauabi, M., Rasmussen, D. N., Bergenheim, F. O., Burisch, J. & Seidelin, Jakob Benedict, 2023, In: Crohn's and Colitis 360. 5, 4, 2 p., otad074.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  10. Published

    Ulcerative Colitis and Acute Severe Ulcerative Colitis Patients Are Overlooked in Infliximab Population Pharmacokinetic Models: Results from a Comprehensive Review

    Démaris, A., Widigson, E. S. K., Ilvemark, J. F. K. F., Steenholdt, Casper, Seidelin, Jakob Benedict, Huisinga, W., Michelet, R., Aulin, L. B. S. & Kloft, C., 2022, In: Pharmaceutics. 14, 10, 2095.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Transdermal nikotinbehandling af colitis ulcerosa: gennemgang af et Cochrane-review

    Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 13 Feb 2006, In: Ugeskrift for Laeger. 168, 7, p. 674-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Transcriptome changes during intestinal cell differentiation

    Tadjali, M., Seidelin, Jakob Benedict, Olsen, Jørgen & Troelsen, J. T., 3 Apr 2002, In: Biochimica et biophysica acta. 1589, 2, p. 160-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Tofacitinib for acute severe ulcerative colitis: a systematic review

    Steenholdt, Casper, Ovesen, P. D., Brynskov, J. & Seidelin, Jakob Benedict, 2023, In: Journal of Crohn's and Colitis. 17, 8, p. 1354-1363

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Tofacitinib and faecal microbiota transplantation in treating checkpoint inhibitor-induced enterocolitis: case report

    Holmstroem, R. B., Dahl, E. K., Helms, Morten, Nielsen, H. V., Andersen, J. B., Bjerrum, Jakob Tveiten , Svane, Inge Marie, Ellebaek, E. & Seidelin, Jakob Benedict, 2022, In: BMJ Open Gastroenterology. 9, 1, 4 p., e000989.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Tissue regenerating functions of coagulation factor XIII

    Soendergaard, C., Kvist, P. H., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2013, In: Journal of Thrombosis and Haemostasis.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The effect of induced hyperammonaemia on sleep and melanopsin-mediated pupillary light response in patients with liver cirrhosis: A single-blinded randomized crossover trial

    Kann, A. E., Ba-Ali, S., Seidelin, Jakob Benedict, Larsen, F. S., Hamann, Steffen & Bjerring, Peter Nissen, 2022, In: PLoS ONE. 17, 9 , e0275067.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The Incidence and Disease Course of Perianal Crohn's Disease: A Danish Nationwide Cohort Study, 1997-2015

    Wewer, M. D., Zhao, M., Nordholm-Carstensen, A., Weimers, P., Seidelin, Jakob Benedict & Burisch, J., 2021, In: Journal of Crohn's and Colitis (JCC). 15, 1, p. 5-13

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes

    Søndergaard, C., Kvist, P. H., Seidelin, Jakob Benedict, Pelzer, H. & Nielsen, Ole Haagen, Aug 2016, In: Journal of Gastroenterology. 51, 8, p. 796-807 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Systematic Review with Meta-analysis: The Impact of Cancer Treatments on the Disease Activity of Inflammatory Bowel Diseases

    Grimsdottir, S., Attauabi, M., Kristine Dahl, E., Burisch, J. & Seidelin, Jakob Benedict, 2023, In: Journal of Crohn's and Colitis. 17, 7, p. 1139-1153 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Species-specific engagement of human nucleotide oligomerization domain 2 (NOD)2 and Toll-like receptor (TLR) signalling upon intracellular bacterial infection: role of Crohn's associated NOD2 gene variants

    Salem, M., Seidelin, Jakob Benedict, Eickhardt-Dalbøge, S. R., Alhede, M., Rogler, G. & Nielsen, Ole Haagen, Mar 2015, In: Clinical and Experimental Immunology. 179, 3, p. 426-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Soluble L-selectin levels predict survival in sepsis

    Seidelin, Jakob Benedict, Nielsen, Ole Haagen & Strøm, J., Nov 2002, In: Intensive Care Medicine. 28, 11, p. 1613-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Simple and efficient method for isolation and cultivation of endoscopically obtained human colonocytes

    Seidelin, Jakob Benedict, Horn, T. & Nielsen, Ole Haagen, Dec 2003, In: A J P: Gastrointestinal and Liver Physiology (Online). 285, 6, p. G1122-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Short and long-term effectiveness and safety of vedolizumab in treatment-refractory patients with ulcerative colitis and Crohn's disease - a real-world two-center cohort study

    Attauabi, M., Vind, Ida, Pedersen, G., Bendtsen, Flemming, Seidelin, Jakob Benedict & Burisch, J., 2021, In: European journal of gastroenterology & hepatology. 33, 15, p. 709-718

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Seizure threshold to lidocaine is decreased following repeated ECS (electroconvulsive shock)

    Kragh, Jesper Vaczy, Seidelin, Jakob Benedict & Bolwig, T. G., 1993, In: Psychopharmacology. 111, 4, p. 495-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Samtidig leptospirose og salmonellainfektion

    Rönsholt, F. F., Seidelin, Jakob Benedict & Villumsen, S., 4 May 2009, In: Ugeskrift for Laeger. 171, 19, p. 1607-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Safety and efficacy of infliximab and corticosteroid therapy in checkpoint inhibitor-induced colitis

    Dahl, E. K., Abed, O. K., Kjeldsen, J., dqp123, dqp123, Svane, Inge Marie, Dige, A., Agnholt, J. S., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, 2022, In: Alimentary Pharmacology and Therapeutics. 56, 9, p. 1370-1382 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases

    Jensen, S., Seidelin, Jakob Benedict, LaCasse, E. C. & Nielsen, Ole Haagen, 2020, In: Science Signaling. 13, 619, 18 p., eaax8295.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Reply to comment on: "Vedolizumab as the first line of biologic therapy for ulcerative colitis and Crohn's disease - a systematic review with meta-analysis"

    Attauabi, M., Seidelin, Jakob Benedict & Burisch, J., 2023, In: Rendiconti di Gastro-Enterologia. 55, 2, p. 300-301

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  29. Published

    Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels

    Chen, Y., Salem, M., Boyd, M., Lange, Jette Bornholdt, Li, Yuan, Coskun, M., Seidelin, Jakob Benedict, Sandelin, Albin Gustav & Nielsen, Ole Haagen, 2017, In: npj Genomic Medicine. 2, 11 p., 3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Regulering af cytokindannelse ved inflammatoriske tarmsygdomme

    Ferrero-Miliani, L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 8 May 2006, In: Ugeskrift for Laeger. 168, 19, p. 1847-50 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Regulation of antiapoptotic and cytoprotective pathways in colonic epithelial cells in ulcerative colitis

    Seidelin, Jakob Benedict, 2015, In: Scandinavian Journal of Gastroenterology. 50 , Suppl 1, p. 1-29 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Recent therapeutic advances in inflammatory bowel disease

    Nielsen, Ole Haagen, Nielsen, S. E. & Seidelin, Jakob Benedict, Jul 2002, In: I Drugs: the Investigational Drugs Journal. 5, 7, p. 618-22 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD

    Soendergaard, C., Seidelin, Jakob Benedict, Steenholdt, C. & Nielsen, Ole Haagen, 2018, In: B M J Open Gastroenterology. 5, 1, e000208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Primary monocytes derived from ulcerative colitis show no difference in the TNF-alpha-induced immune response among responders and primary non-responders to infliximab

    Li, Y., Jensen, Kim Bak, Seidelin, Jakob Benedict & Nielsen, O. H., Sep 2017, In: Journal of Gastroenterology and Hepatology. 32, S3, p. 138-138 P-0750.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  35. Published

    Prevalence and outcomes of COVID-19 among patients with inflammatory bowel disease: A Danish prospective population-based cohort study

    Attauabi, M., Poulsen, A., Theede, K., Pedersen, N., Larsen, L., Jess, T., Rosager Hansen, M., Kajbæk Verner-Andersen, M., V Haderslev, K., Berg Lødrup, A., Molazahi, A., Neumann, A., Wase, A., Seidelin, Jakob Benedict & Burisch, J., 2021, In: Journal of Crohn's and Colitis. 15, 4, p. 540–550

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Predictors of response and disease course in patients with inflammatory bowel disease treated with biological therapy - The Danish IBD Biobank Project: protocol for a multicentre prospective cohort study

    Zhao, M., Bendtsen, Flemming, Petersen, Andreas Munk, Larsen, L., Dige, A., Hvas, C., Seidelin, Jakob Benedict & Burisch, J., 2020, In: BMJ Open. 10, 2, 7 p., e035756.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Prediction of Relapse After Anti–Tumor Necrosis Factor Cessation in Crohn's Disease: Individual Participant Data Meta-analysis of 1317 Patients From 14 Studies

    Pauwels, R. W. M., van der Woude, C. J., Nieboer, D., Steyerberg, E. W., Casanova, M. J., Gisbert, J. P., Kennedy, N. A., Lees, C. W., Louis, E., Molnár, T., Szántó, K., Leo, E., Bots, S., Downey, R., Lukas, M., Lin, W. C., Amiot, A., Lu, C., Roblin, X., Farkas, K. & 15 others, Seidelin, Jakob Benedict, Duijvestein, M., D'Haens, G. R., de Vries, A. C., Janneke van der Woude, C., Sleutjes, J. A. M., García-Ortiz, J. M., Brooks, A. J., Hamlin, P. J., Sebastian, S., Lobo, A. J., Dieleman, L. (. A., Ben-Horin, S., Steenholdt, Casper & CEASE Study Group, C. S. G., 2022, In: Clinical Gastroenterology and Hepatology. 20, 8, p. 1671-1686.e16

    Research output: Contribution to journal › Review › Research › peer-review

  38. E-pub ahead of print

    Predicting treatment response in ASUC: do we measure systemic severity, organ response or both?

    Ovesen, P. D., Ilvemark, J. F. K. F., Wilkens, R., Steenholdt, Casper & Seidelin, Jakob Benedict, 1 Apr 2024, (E-pub ahead of print) In: Gut. 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  39. Published

    Praktisk anvendelse af thiopuriner hos patienter med kronisk inflammatoriske tarmsygdomme

    Zhao, M., Wewer, M. D., Bjerrum, Jakob Tveiten , Steenholdt, Casper, Schiødt, Frank Vinholt, Haderslev, K., Kiszka-Kanowitz, M., Munkholm, Pia, Seidelin, Jakob Benedict & Burisch, J., 2022, In: Ugeskrift for Laeger. 184, 11, V09210706.

    Research output: Contribution to journal › Review › Research › peer-review

  40. E-pub ahead of print

    Peripheral joint and enthesis involvement in patients with newly diagnosed inflammatory bowel disease: symptoms, clinical and ultrasound findings - a population-based cohort study

    Vladimirova, N., Terslev, Lene, Attauabi, M., Madsen, G., Fana, V., Wiell, C., Døhn, U. M., Bendtsen, Flemming, Seidelin, Jakob Benedict, Burisch, J. & Østergaard, Mikkel, 2024, (E-pub ahead of print) In: Journal of Crohn's & colitis.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis

    Thorsteinsdottir, S., Gudjónsson, Thorkell, Nielsen, Ole Haagen, Vainer, B. & Seidelin, Jakob Benedict, 7 Jun 2011, In: Nature Reviews. Gastroenterology & Hepatology. 8, 7, p. 395-404 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Outcomes and long-term effects of COVID-19 in patients with inflammatory bowel diseases - a Danish prospective population-based cohort study with individual-level data

    Attauabi, M., Dahlerup, J. F., Poulsen, A., Hansen, M. R., Verner-Andersen, M. K., Eraslan, S., Prahm, A. P., Pedersen, N., Larsen, L., Jess, T., Neumann, A., Haderslev, K. V., Molazahi, A., Lødrup, A. B., Glerup, H., Oppfeldt, A. M., Jensen, M. D., Theede, K., Kiszka-Kanowitz, M., Seidelin, J. B. & 1 others, Burisch, J., 2022, In: Journal of Crohn's and Colitis. 16, 5, p. 757–767 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Outcome after discontinuation of infliximab in patients with inflammatory bowel disease in clinical remission: an observational Danish single center study

    Steenholdt, C., Molazahi, A., Ainsworth, M. A., Brynskov, J., Thomsen, O. Ø. & Seidelin, Jakob Benedict, 2012, In: Scandinavian Journal of Gastroenterology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Optimizing Screening for Colorectal Cancer: An Algorithm Combining Fecal Immunochemical Test, Blood-Based Cancer-Associated Proteins and Demographics to Reduce Colonoscopy Burden

    Petersen, M. M., Kleif, Jakob, Jørgensen, Lars Nannestad, Hendel, J. W., Seidelin, Jakob Benedict, Madsen, M. R., Vilandt, J., Brandsborg, S., Rasmussen, J. S., Andersen, L. M., Khalid, A., Ferm, L., Gawel, S. H., Martens, F., Andersen, B., Rasmussen, Morten, Davis, G. J., Christensen, I. J. & Therkildsen, C., 2023, In: Clinical Colorectal Cancer. 22, 2, p. 199-210 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Objective Quantification of Immune Cell Infiltrates and Epidermal Proliferation in Psoriatic Skin: A Comparison of Digital Image Analysis and Manual Counting

    Soendergaard, C., Nielsen, Ole Haagen, Skak, K., Røpke, M. A., Seidelin, Jakob Benedict & Kvist, P. H., 2015, In: Applied Immunohistochemistry & Molecular Morphology. p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Noninfectious & noninflammatory bowel disease colitis

    Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, 1 Mar 2013, Advances in the Management of Inflammatory Bowel Disease. Future Medicine Ltd., p. 33-49 17 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  47. Published

    Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond

    Salem, M., Seidelin, Jakob Benedict, Rogler, G. & Nielsen, Ole Haagen, 2013, In: Cellular and Molecular Life Sciences. 70, p. 3391-3404

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Mucosal healing in ulcerative colitis: pathophysiology and pharmacology

    Seidelin, Jakob Benedict, Coskun, M. & Nielsen, Ole Haagen, 2013, In: Advances in Clinical Chemistry. 59, p. 101-23 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    MicroRNAs in inflammatory bowel disease--pathogenesis, diagnostics and therapeutics

    Coskun, M., Bjerrum, J. T., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2012, In: World Journal of Gastroenterology. 18, 34, p. 4629-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    MAP kinases in inflammatory bowel disease

    Coskun, M., Olsen, Jørgen, Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2011, In: Clinica Chimica Acta. 412, 7-8, p. 513-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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