Bo Torben Porse
Professor, Clinical Professor
Porse Group
Københavns Universitet, BRIC, Ole Maaløes Vej 5
2200 København N
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Haematology
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Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML
Rapin, N. & Porse, Bo Torben, 2014, In: Oncogenesis. 3, p. 1-5 5 p., e106.Research output: Contribution to journal › Letter › Research › peer-review
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Overall Survival in Patients with Ccus Depends on Presence of Anemia
Træden, D., Tulstrup, Morten Rytter, Johansen, M. M., Ørskov, A. D., Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-mönch, K., Jespersen, Jakob Schmidt, Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, J. W., 2023, In: Blood. 142, Suppl. 1, p. 1864-1865Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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PRDM11 is dispensable for the maintenance and function of hematopoietic stem and progenitor cells
Thoren, L. A., Fog, C. K., Jensen, K. T., Buza-Vidas, N., Côme, Christophe Roger Michel, Lund, Anders H. & Porse, Bo Torben, 9 Aug 2013, In: Stem Cell Research. 11, 3, p. 1129-1136 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2
Zheng, S., Gray, E. E., Chawla, G., Porse, Bo Torben, O'Dell, T. J. & Black, D. L., Mar 2012, In: Nature Neuroscience. 15, 3, p. 381-8, S1Research output: Contribution to journal › Journal article › Research › peer-review
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PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents
Rehn, M., Wenzel, Anne, Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jørgensen, N., Vitting-Seerup, K., Ge, Y., Jendholm, J., Michaut, Magali, Schoof, E. M., Jensen, T. L., Rapin, N., Sapio, R. T., Andersen, Kasper Langebjerg, Lund, Anders H., Solimena, M., Holzenberger, M., Pestov, D. G. & Porse, Bo Torben, 2022, In: Cell Reports. 39, 6, 28 p., 110793.Research output: Contribution to journal › Journal article › Research › peer-review
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Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality
Pundhir, Sachin, Bagger, F. O., Lauridsen, F. K. B., Rapin, N. P. J. & Porse, Bo Torben, 2016, In: Nucleic Acids Research. 44, 9, p. 4037-4051 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome
Kirillov, S. V., Porse, Bo Torben & Garrett, R. A., 1999, In: RNA: A publication of the RNA Society. 5, 8, p. 1003-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphorylation of Serine 248 of C/EBPa Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency
Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Theilgaard-Mønch, Kim, Pedersen, T. Å., Nerlov, C. & Porse, Bo Torben, 2012, In: P L o S One. 7, 6, p. e38841Research output: Contribution to journal › Journal article › Research › peer-review
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Progression of the pluripotent epiblast depends upon the NMD factor UPF2
Chousal, J. N., Sohni, A., Vitting-Seerup, K., Cho, K., Kim, M., Tan, K., Porse, Bo Torben, Wilkinson, M. F. & Cook-Andersen, H., 2022, In: Development. 149, 21, 15 p., dev200764.Research output: Contribution to journal › Journal article › Research › peer-review
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Proinflammatory cytokines suppress nonsense-mediated RNA decay to impair regulated transcript isoform processing in pancreatic β cells
Ghiasi, S. M., Marchetti, P., Piemonti, L., Nielsen, Jens Høiriis, Porse, Bo Torben, Mandrup-Poulsen, Thomas & Rutter, G. A., 2024, In: Frontiers in Endocrinology. 15, 13 p., 1359147.Research output: Contribution to journal › Journal article › Research › peer-review
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Puromycin-rRNA interaction sites at the peptidyl transferase center
Rodriguez-Fonseca, C., Phan, H., Long, K. S., Porse, Bo Torben, Kirilov, S. V., Amils, R. & Garrett, Roger Antony, 2000, In: RNA: A publication of the RNA Society. 6, 5, p. 744-754 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative single-cell proteomics as a tool to characterize cellular hierarchies
Schoof, E. M., Furtwängler, Benjamin, Üresin, Nil, Rapin, N., Savickas, S., Gentil, C., Lechman, E., Keller, U. A. D., Dick, J. E. & Porse, Bo Torben, 7 Jun 2021, In: Nature Communications. 12, 1, p. 3341Research output: Contribution to journal › Journal article › Research › peer-review
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Real-Time Search Assisted Acquisition on a Tribrid Mass Spectrometer Improves Coverage in Multiplexed Single-Cell Proteomics
Furtwängler, Benjamin, Üresin, Nil, Motamedchaboki, K., Huguet, R., Lopez-Ferrer, D., Zabrouskov, V., Porse, Bo Torben & Schoof, E. M., 2022, In: Molecular and Cellular Proteomics. 21, 4, 100219.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation
Rishi, L., Hannon, M., Salomè, M., Hasemann, M., Frank, Anne-Katrine, Campos, J., Timoney, J., O'Connor, C., Cahill, M. R., Porse, Bo Torben & Keeshan, K., 10 Apr 2014, In: Blood. 123, 15, p. 2389-400 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay
Colak, D., Ji, S., Porse, Bo Torben & Jaffrey, S. R., 2013, In: Cell. 153, 6, p. 1252-65 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ribosomal mechanics, antibiotics, and GTP hydrolysis.
Porse, Bo Torben & Garrett, R. A., 1999, In: Cell. 97, 4, p. 423-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SinaPlot: an enhanced chart for simple and truthful representation of single observations over multiple classes
Sidiropoulos, N., Sohi, S. H., Pedersen, T. L., Porse, Bo Torben, Winther, Ole, Rapin, N. & Bagger, F. O., 2018, In: Journal of Computational and Graphical Statistics. 27, 3, p. 673-676 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their binding mechanisms
Porse, Bo Torben & Garrett, Roger Antony, 1999, In: Journal of Molecular Biology. 286, p. 375-387Research output: Contribution to journal › Journal article › Research › peer-review
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Sites of interaction of streptogramin A and B antibiotics in the peptidyl transferase loop of 23 S rRNA and the synergism of their inhibitory mechanisms.
Porse, Bo Torben & Garrett, R. A., 1999, In: Journal of Molecular Biology. 286, 2, p. 375-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Systems biology of neutrophil differentiation and immune response.
Theilgaard-Mønch, Kim, Porse, Bo Torben & Borregaard, N., 2005, In: Current Opinion in Immunology. 18, 1, p. 54-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia
Willer, A., Jakobsen, J. S., Ohlsson, E., Rapin, N., Waage, J., Billing, M., Bullinger, L., Karlsson, S. & Porse, Bo Torben, 2015, In: Leukemia. 29, p. 1018-31 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy
Estruch Alrich, Montserrat, Reckzeh, K., Vittori, Camilla, Centio, A., Ali, M., Engelhard, Sophia Manon Charlotte, Zhao, L., Won, K. J., Liu, P., Porse, Bo Torben & Theilgaard-Mønch, Kim, 2021, In: Leukemia. 35, p. 2030-2042Research output: Contribution to journal › Journal article › Research › peer-review
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Technical advance: immunophenotypical characterization of human neutrophil differentiation
Mora-Jensen, H. I., Jendholm, J., Fossum, A., Porse, Bo Torben, Borregaard, N. & Theilgaard-Mönch, K., 2011, In: Journal of Leukocyte Biology. 90, 3, p. 629-34 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries
Jakobsen, J. S., Waage, J., Rapin, N., Bisgaard, Hanne Cathrine, Larsen, F. S. & Porse, Bo Torben, Apr 2013, In: Genome Research. 23, 4, p. 592-603 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testosterone is an endogenous regulator of BAFF and splenic B cell number
Wilhelmson, A. S., Lantero Rodriguez, M., Stubelius, A., Fogelstrand, P., Johansson, I., Buechler, M. B., Lianoglou, S., Kapoor, V. N., Johansson, M. E., Fagman, J. B., Duhlin, A., Tripathi, P., Camponeschi, A., Porse, B. T., Rolink, A. G., Nissbrandt, H., Turley, S. J., Carlsten, H., Mårtensson, I-L., Karlsson, M. C. I. & 1 others, , 2018, In: Nature Communications. 9, p. 1-13 13 p., 2067.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4985646
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spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data
Research output: Contribution to journal › Journal article › Research › peer-review
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Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
Research output: Contribution to journal › Journal article › Research › peer-review
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2497
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HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis
Research output: Contribution to journal › Journal article › Research › peer-review
Published