Evaluation of HIV protease inhibitor use and the risk of sudden death or nonhemorrhagic stroke
Research output: Contribution to journal › Journal article › Research › peer-review
Concerns have arisen about possible effects of protease inhibitors (PIs) on cardiac conductivity. We found no significant association between current or recent PI exposure and sudden death or nonhemorrhagic stroke (adjusted rate ratio, 1.22; 95% confidence interval, .95-1.57), whereas cumulative exposure to PIs was associated with an increased risk (adjusted rate ratio, 1.06 per year of exposure; 95% confidence interval, 1.01-1.11).
| Original language | English |
|---|---|
| Journal | The Journal of Infectious Diseases |
| Volume | 205 |
| Issue number | 4 |
| Pages (from-to) | 535-9 |
| Number of pages | 5 |
| ISSN | 0022-1899 |
| DOIs | |
| Publication status | Published - 15 Feb 2012 |
- Adult, Death, Sudden, Female, HIV Infections, HIV Protease Inhibitors, Humans, Male, Middle Aged, Risk Assessment, Stroke
Research areas
ID: 47789504