Impact of HIV-1 reverse transcriptase polymorphism F214L on virological response to thymidine analogue-based regimens in antiretroviral therapy (ART)-naive and ART-experienced patients

Research output: Contribution to journalJournal articleResearchpeer-review

  • Francesca Ceccherini-Silberstein
  • Alessandro Cozzi-Lepri
  • Lidia Ruiz
  • Amanda Mocroft
  • Andrew N Phillips
  • Christian Holkmann Olsen
  • Jose M Gatell
  • Huldrych F Gunthard
  • Peter Reiss
  • Carlo Federico Perno
  • Bonaventura Clotet
  • Lundgren, Jens
  • Eurosida Study Group
A negative association between the polymorphism F214L and type 1 thymidine analogue (TA) mutations (TAMs) has been observed. However, the virological response to TAs according to the detection of F214L has not been evaluated.
Original languageEnglish
JournalJournal of Infectious Diseases
Volume196
Issue number8
Pages (from-to)1180-90
Number of pages11
ISSN0022-1899
DOIs
Publication statusPublished - 2007

    Research areas

  • Europe, HIV Infections, HIV Reverse Transcriptase, HIV-1, Humans, Mutation, Polymorphism, Single Nucleotide, Retrospective Studies, Reverse Transcriptase Inhibitors, Thymidine

ID: 4033529