Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: a randomized trial
Research output: Contribution to journal › Journal article › Research › peer-review
For patients in intensive care units, sepsis is a common and potentially deadly complication and prompt initiation of appropriate antimicrobial therapy improves prognosis. The objective of this trial was to determine whether a strategy of antimicrobial spectrum escalation, guided by daily measurements of the biomarker procalcitonin, could reduce the time to appropriate therapy, thus improving survival.
| Original language | English |
|---|---|
| Journal | Critical Care Medicine |
| Volume | 39 |
| Issue number | 9 |
| Pages (from-to) | 2048-58 |
| Number of pages | 11 |
| ISSN | 0090-3493 |
| DOIs | |
| Publication status | Published - 1 Sep 2011 |
- Aged, Algorithms, Anti-Bacterial Agents, Biological Markers, Calcitonin, Female, Hospital Mortality, Humans, Intensive Care Units, Length of Stay, Male, Middle Aged, Protein Precursors, Respiration, Artificial, Sepsis, Time Factors
Research areas
ID: 35412675