Schistosomiasis and HIV-1 infection in rural Zimbabwe: effect of treatment of schistosomiasis on CD4 cell count and plasma HIV-1 RNA load
Research output: Contribution to journal › Journal article › Research › peer-review
To determine whether treatment of schistosomiasis has an effect on the course of human immunodeficiency virus type 1 (HIV-1) infection, individuals with schistosomiasis and with or without HIV-1 infection were randomized to receive praziquantel treatment at inclusion or after a delay of 3 months; 287 participants were included in the study, and 227 (79%) were followed up. Among the 130 participants who were coinfected, those who received early treatment (n=64) had a significantly lower increase in plasma HIV-1 RNA load than did those who received delayed treatment (n=66) (P
| Original language | English |
|---|---|
| Journal | Journal of Infectious Diseases |
| Volume | 192 |
| Issue number | 11 |
| Pages (from-to) | 1956-61 |
| Number of pages | 6 |
| ISSN | 0022-1899 |
| DOIs | |
| Publication status | Published - 2005 |
- Adult, Anthelmintics, CD4 Lymphocyte Count, Drug Administration Schedule, Female, HIV Infections, HIV-1, Humans, Male, Praziquantel, RNA, Viral, Rural Population, Schistosomiasis, Treatment Outcome, Viral Load, Zimbabwe
Research areas
ID: 36143832