Gitte Moos Knudsen
Clinical Professor
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Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors
Hansen, H. D., Herth, Matthias Manfred, Ettrup, A., Andersen, V. L., Lehel, S., Dyssegaard, A., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 24 Feb 2014, In: Journal of Nuclear Medicine. 55, 4, p. 640-646Research output: Contribution to journal › Journal article › Research › peer-review
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Functional characterization of 5-HT1B receptor drugs in nonhuman primates using simultaneous PET-MR
Hansen, H. D., Mandeville, J. B., Sander, C. Y., Hooker, J. M., Catana, C., Rosen, B. R. & Knudsen, Gitte Moos, Nov 2017, In: Journal of Neuroscience. 37, 44, p. 10671-10678 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of [18F]2FP3 in pigs and non-human primates
Hansen, H. D., Constantinescu, C. C., Barret, O., Herth, Matthias Manfred, Magnussen, J. H., Lehel, S., Dyssegaard, A., Colomb, J., Billard, T., Zimmer, L., Tamagnan, G. & Knudsen, Gitte Moos, 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, 1, p. 34-42Research output: Contribution to journal › Journal article › Research › peer-review
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Visual stimuli induce serotonin release in occipital cortex: A simultaneous positron emission tomography/magnetic resonance imaging study
Hansen, H. D., Lindberg, U., Ozenne, Brice Maxime Hugues, Fisher, P. M., Johansen, A., Svarer, C., Keller, S. H., Hansen, Adam Espe & Knudsen, Gitte Moos, 2020, In: Human Brain Mapping. 41, 16, p. 4753-4763 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mapping neurotransmitter systems to the structural and functional organization of the human neocortex
Hansen, J. Y., Shafiei, G., Markello, R. D., Smart, K., Cox, S. M. L., Nørgaard, M., Beliveau, V., Wu, Y., Gallezot, J-D., Aumont, É., Servaes, S., Scala, S. G., DuBois, J. M., Wainstein, G., Bezgin, G., Funck, T., Schmitz, T. W., Spreng, R. N., Galovic, M., Koepp, M. J. & 22 others, , 2022, In: Nature Neuroscience. 25, p. 1569–1581Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral glucose metabolism is decreased in white matter changes in patients with phenylketonuria
Hasselbalch, Steen, Knudsen, Gitte Moos, Toft, Peter Bjerre, Høgh, P., Tedeschi, E., Holm, S., Videbaek, C., Henriksen, O., Lou, H. C. & Paulson, Olaf B., Jul 1996, In: Pediatric Research. 40, 1, p. 21-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Estimation of unidirectional clearances of FDG and glucose across the blood-brain barrier in man
Hasselbalch, Steen, Knudsen, Gitte Moos, Jakobsen, J., Holm, S. & Paulson, Olaf B., 1993, Frontiers in cerebral vascular biology: Transport and its regulation. Drewes, L. & Betz, A. L. (eds.). New York: Plenum Press, Vol. 331. p. 25-7 3 p. (Advances in Experimental Medicine and Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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The (18)F-fluorodeoxyglucose lumped constant determined in human brain from extraction fractions of (18)F-fluorodeoxyglucose and glucose
Hasselbalch, Steen, Holm, S., Pedersen, H. S., Svarer, C., Knudsen, Gitte Moos, Madsen, P. L. & Paulson, Olaf B., Aug 2001, In: Journal of Cerebral Blood Flow and Metabolism. 21, 8, p. 995-1002 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No effect of insulin on glucose blood-brain barrier transport and cerebral metabolism in humans
Hasselbalch, Steen, Knudsen, Gitte Moos, Videbaek, C., Pinborg, Lars Hageman, Schmidt, J. F., Holm, S. & Paulson, Olaf B., Oct 1999, In: Diabetes. 48, 10, p. 1915-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood-brain barrier permeability of glucose and ketone bodies during short-term starvation in humans
Hasselbalch, Steen, Knudsen, Gitte Moos, Jakobsen, J., Hageman, L. P., Holm, S. & Paulson, Olaf B., Jun 1995, In: The American Journal of Physiology. 268, 6 Pt 1, p. E1161-6Research output: Contribution to journal › Journal article › Research › peer-review
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Blood-brain barrier transport and brain metabolism of glucose during acute hyperglycemia in humans
Hasselbalch, Steen, Knudsen, Gitte Moos, Capaldo, B., Postiglione, A. & Paulson, Olaf B., May 2001, In: The Journal of clinical endocrinology and metabolism. 86, 5, p. 1986-90 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Brain metabolism during short-term starvation in humans
Hasselbalch, Steen, Knudsen, Gitte Moos, Jakobsen, J., Hageman, L. P., Holm, S. & Paulson, Olaf B., Jan 1994, In: Journal of Cerebral Blood Flow and Metabolism. 14, 1, p. 125-31 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Calculation of the FDG lumped constant by simultaneous measurements of global glucose and FDG metabolism in humans
Hasselbalch, Steen, Madsen, P. L., Knudsen, Gitte Moos, Holm, S. & Paulson, Olaf B., Feb 1998, In: Journal of Cerebral Blood Flow and Metabolism. 18, 2, p. 154-60 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transport of D-glucose and 2-fluorodeoxyglucose across the blood-brain barrier in humans
Hasselbalch, Steen, Knudsen, Gitte Moos, Holm, S., Hageman, L. P., Capaldo, B. & Paulson, Olaf B., Jul 1996, In: Journal of Cerebral Blood Flow and Metabolism. 16, 4, p. 659-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Total synthesis and evaluation of [18F]MHMZ
Herth, Matthias Manfred, Debus, F., Piel, M., Palner, M., Knudsen, Gitte Moos, Lüddens, H. & Rösch, F., 2008, In: Bioorganic & Medicinal Chemistry Letters. 18, 4, p. 1515-1519 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PET Imaging of the 5-HT2A Receptor System: A Tool to Study the Receptor’s In Vivo Brain Function
Herth, Matthias Manfred & Knudsen, Gitte Moos, 2018, 5-HT2A Receptors in the Central Nervous System. Guiard, B. P. & Di Giovanni, G. (eds.). Humana Press, p. 85-134 (Receptors Series).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Synthesis and evaluation of [11C]Cimbi-806 as a potential PET ligand for 5-HT7 receptor imaging
Herth, Matthias Manfred, Hansen, H. D., Ettrup, A. J., Dyssegaard, A., Lehel, S., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 2012, In: Bioorganic and Medicinal Chemistry. 20, 14, p. 4574-4581 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET
Herth, Matthias Manfred, Kramer, V., Piel, M., Palner, M., Riss, P. J., Knudsen, Gitte Moos & Roesch, F., 2009, In: Bioorganic & Medicinal Chemistry. 17, 8, p. 2989-3002Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a 11C-labeled tetrazine for rapid tetrazine–trans-cyclooctene ligation
Herth, Matthias Manfred, Andersen, V. L., Lehel, S., Madsen, J., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Chemical Communications. 49, p. 3805-3807 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and In Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT7 Receptor Imaging with PET
Herth, Matthias Manfred, Volk, B., Pallagi, K., Koefoed Bech, L., A. Antoni, F., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 31 Aug 2012, In: ACS Chemical Neuroscience. 3, 12, p. 1002-1007Research output: Contribution to journal › Journal article › Research › peer-review
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Psychometric Properties of the Verbal Affective Memory Test-26 and Evaluation of Affective Biases in Major Depressive Disorder
Hjordt, L. V., Ozenne, Brice Maxime Hugues, Armand, Sophia, Dam, V. H., Jensen, C. G., Köhler-Forsberg, K., Knudsen, Gitte Moos & Stenbæk, Dea Siggaard, 2020, In: Frontiers in Psychology. 11, 15 p., 961.Research output: Contribution to journal › Journal article › Research › peer-review
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State-Dependent Alterations in Inhibitory Control and Emotional Face Identification in Seasonal Affective Disorder
Hjordt, L. V., Stenbæk, D. S., Madsen, K. S., Mc Mahon, B., Jensen, C. G., Vestergaard, M., Hageman, Ida, Meder, D., Hasselbalch, Steen & Knudsen, Gitte Moos, Apr 2017, In: Journal of Abnormal Psychology. 126, 3, p. 291-300 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Season-independent cognitive deficits in seasonal affective disorder and their relation to depressive symptoms
Hjordt, L. V., Stenbæk, D. S., Ozenne, Brice Maxime Hugues, Mc Mahon, B., Hageman, Ida, Hasselbalch, Steen & Knudsen, Gitte Moos, Nov 2017, In: Psychiatry Research. 257, p. 219-226 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Self-perceived personality characteristics in seasonal affective disorder and their implications for severity of depression
Hjordt, L. V., Dam, V. H., Ozenne, B., Hageman, Ida, Mc Mahon, B., Mortensen, Erik Lykke, Knudsen, Gitte Moos & Stenbæk, D. S., 2018, In: Psychiatry Research. 262, p. 108-114 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice
Holm, P., Ettrup, A., Klein, A. B., Santini, M. A., El-Sayed, M., Elvang, A. B., Stensbøl, T. B., Mikkelsen, Jens D., Knudsen, Gitte Moos & Kleijn, S. A., 1 Jan 2010, In: Journal of Alzheimer's Disease. 20, 4, p. 1201-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neuroticism predicts the impact of serotonin challenges on fear processing in subgenual anterior cingulate cortex
Hornboll, B., Macoveanu, J., Nejad, A., Rowe, James Benedict, Elliott, R., Knudsen, Gitte Moos, Siebner, Hartwig Roman & Paulson, Olaf B., 2018, In: Scientific Reports. 8, 10 p., 17889.Research output: Contribution to journal › Journal article › Research › peer-review
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A multidisciplinary memory clinic in a neurological setting: diagnostic evaluation of 400 consecutive patients
Høgh, Peter, Waldemar, Gunhild, Knudsen, Gitte Moos, Bruhn, P., Mortensen, H., Wildschiødtz, G., Bech, R. A., Juhler, Marianne & Paulson, Olaf B., May 1999, In: European Journal of Neurology. 6, 3, p. 279-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single photon emission computed tomography and apolipoprotein E in Alzheimer's disease: impact of the epsilon4 allele on regional cerebral blood flow
Høgh, Peter, Knudsen, Gitte Moos, Kjaer, K. H., Jørgensen, O. S., Paulson, Olaf B. & Waldemar, Gunhild, 2001, In: Journal of Geriatric Psychiatry and Neurology. 14, 1, p. 42-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apoliprotein E and multiple sclerosis: impact of the epsilon-4 allele on susceptibility, clinical type and progression rate
Høgh, Peter, Oturai, A., Schreiber, K., Blinkenberg, M., Jørgensen, O. S., Ryder, L., Paulson, Olaf B., Sørensen, Per Soelberg & Knudsen, Gitte Moos, Aug 2000, In: Multiple Sclerosis Journal. 6, 4, p. 226-30 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pretreatment qEEG biomarkers for predicting pharmacological treatment outcome in major depressive disorder: Independent validation from the NeuroPharm study
Ip, C. T., Olbrich, S., Ganz, Melanie, Ozenne, Brice Maxime Hugues, Köhler-Forsberg, K., Dam, V. H., Beniczky, S., Jørgensen, Martin Balslev, Frøkjær, Vibe Gedsø, Søgaard, B., Christensen, S. R. & Knudsen, Gitte Moos, Aug 2021, In: European Neuropsychopharmacology. 49, p. 101-112 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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NeuroPharm study: EEG wakefulness regulation as a biomarker in MDD
Ip, C. T., Ganz, Melanie, Dam, V. H., Ozenne, Brice Maxime Hugues, Rüesch, A., Köhler-Forsberg, K., Jørgensen, Martin Balslev, Frøkjær, Vibe Gedsø, Søgaard, B., Christensen, S. R., Knudsen, Gitte Moos & Olbrich, S., 2021, In: Journal of Psychiatric Research. 141, p. 57-65 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pre-intervention test-retest reliability of EEG and ERP over four recording intervals
Ip, C., Ganz, Melanie, Ozenne, Brice Maxime Hugues, Sluth, L. B., Gram, M., Viardot, G., l'Hostis, P., Danjou, P., Knudsen, Gitte Moos & Christensen, S. R., 1 Dec 2018, In: International Journal of Psychophysiology. 134, p. 30-43Research output: Contribution to journal › Journal article › Research › peer-review
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Association between the loudness dependence of auditory evoked potential, serotonergic neurotransmission and treatment outcome in patients with depression
Ip, C., Ganz, Melanie, Ozenne, Brice Maxime Hugues, Olbrich, S., Beliveau, V., Dam, V. H., Köhler-Forsberg, K., Jørgensen, Martin Balslev, Frøkjær, Vibe Gedsø & Knudsen, Gitte Moos, 2023, In: European Neuropsychopharmacology. 70, p. 32-44 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT4 receptor levels
Jennings, K. A., Licht, C. L., Bruce, A., Lesch, K., Knudsen, Gitte Moos & Sharp, T., 2012, In: International Journal of Neuropsychopharmacology. 15, 8, p. 1099-1107 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Radiosynthesis and Evaluation of [(11)C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites
Jensen, C. H., Hansen, H. D., Bay, T., Vogensen, S. B., Lehel, S., Thiesen, L., Bundgaard, C., Clausen, Rasmus Prætorius, Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, 18 Jan 2017, In: A C S Chemical Neuroscience. 8, 1, p. 22-27 6 p.Research output: Contribution to journal › Letter › Research › peer-review
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Precision medicine in the treatment of first-episode depression - establishing the BrainDrugs-Depression Cohort
Jensen, K. R., Dam, V. H., Ganz, Melanie, Fisher, P. M., Osler, M., Frøkjær, Vibe Gedsø, Knudsen, Gitte Moos & Jørgensen, Martin Balslev, 2021, In: European Neuropsychopharmacology. 53, p. S416-S417Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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EEG abnormalities are not associated with poor antidepressant treatment outcome - A NeuroPharm study
Jensen, Kristian HR, Urdanibia-Centelles, O., Dam, V. H., Köhler-Forsberg, K., Frøkjær, Vibe Gedsø, Knudsen, Gitte Moos, Jørgensen, Martin Balslev & Ip, C. T., 2024, In: European Neuropsychopharmacology. 79, p. 59-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deep phenotyping towards precision psychiatry of first-episode depression - the Brain Drugs-Depression cohort
Jensen, Kristian HR, Dam, V. H., Ganz, Melanie, Fisher, Patrick Mac Donald, Ip, C., Sankar, A., Marstrand-Joergensen, M. R., Ozenne, Brice Maxime Hugues, Osler, Merete, Penninx, B. W. J. H., Pinborg, Lars Hageman, Frokjaer, V. G., Knudsen, Gitte Moos & Jørgensen, Martin Balslev, 2023, In: BMC Psychiatry. 23, 1, 15 p., 151.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 receptor regulation of basal dopamine transporter activity is species-dependent
Jensen, M. E., Galli, A., Thomsen, M., Jensen, Kathrine Louise, Thomsen, G. K., Klausen, M. K., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul, Owens, A., Robertson, S., Daws, L., Zanella, D., Gether, Ulrik, Knudsen, Gitte Moos & Fink-Jensen, Anders, 2020, In: Neurochemistry International. 138, 9 p., 104772.Research output: Contribution to journal › Journal article › Research › peer-review
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Psilocybin-assisted therapy for reducing alcohol intake in patients with alcohol use disorder: protocol for a randomised, double-blinded, placebo-controlled 12-week clinical trial (The QUANTUM Trip Trial)
Jensen, M. E., Stenbæk, Dea Siggaard, Juul, T. S., Fisher, P. M., Ekstrøm, Claus Thorn, Knudsen, Gitte Moos & Fink-Jensen, Anders, 2022, In: BMJ Open. 12, 10, 12 p., 066019.Research output: Contribution to journal › Journal article › Research › peer-review
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Validation of a method for accurate and highly reproducible quantification of brain dopamine transporter SPECT studies
Jensen, P. S., Ziebell, M., Skouboe, G., Khalid, U., de Nijs, R., Thomsen, G., Knudsen, Gitte Moos & Svarer, C., 2011, In: Journal of Nuclear Medicine Technology. 39, 4, p. 271-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of immersive virtual reality-based cognitive remediation in patients with mood or psychosis spectrum disorders: study protocol for a randomized, controlled, double-blinded trial
Jespersen, Andreas Elleby, Lumbye, A., Vinberg, Maj, Glenthøj, Louise Birkedal, Nordentoft, Merete, Wæhrens, E. E., Knudsen, Gitte Moos, Makransky, Guido & Miskowiak, Kamilla, 2024, In: Trials. 25, 1, 14 p., 82.Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions
Johansen, A., Hansen, H. D., Svarer, C., Lehel, S., Leth-Petersen, S., Kristensen, Jesper Langgaard, Gillings, N. & Knudsen, Gitte Moos, Apr 2018, In: Journal of Cerebral Blood Flow and Metabolism. 38, 4, p. 659-668Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial
Johansen, A., Armand, Sophia, Plavén-Sigray, P., Nasser, A., Ozenne, Brice Maxime Hugues, Petersen, I. N., Keller, S. H., Madsen, J., Beliveau, V., Møller, Kirsten, Vassilieva, A., Langley, C., Svarer, C., Stenbæk, Dea Siggaard, Sahakian, B. J. & Knudsen, Gitte Moos, 2024, In: Molecular Psychiatry. p. 4272–4279 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions
Johansen, A., Holm, S., Dall, B., Keller, S., Kristensen, Jesper Langgaard, Knudsen, Gitte Moos & Hansen, H. D., 2019, In: EJNMMI Research. 9, p. 1-10 10 p., 71.Research output: Contribution to journal › Journal article › Research › peer-review
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Systemic DNA and RNA damage from oxidation after serotonergic treatment of unipolar depression
Jørgensen, Anders, Köhler-Forsberg, K., Henriksen, T., Weimann, A., Brandslund, I., Ellervik, Christina, Poulsen, Henrik Enghusen, Knudsen, Gitte Moos, Frøkjær, Vibe Gedsø & Jørgensen, Martin Balslev, 2022, In: Translational Psychiatry. 12, 8 p., 204.Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice
Jørgensen, C. V., Jacobsen, J. P., Caron, M. G., Klein, A. B., Knudsen, Gitte Moos & Mikkelsen, Jens D., 25 Oct 2013, In: Neuroscience Letters. 555, p. 118-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of childhood trauma with cognitive impairment and structural brain alterations in remitted patients with bipolar disorder
Jørgensen, J. L., Macoveanu, J., Petersen, J. Z., Knudsen, Gitte Moos, Kessing, Lars Vedel, Jørgensen, Martin Balslev & Miskowiak, Kamilla, 2023, In: Journal of Affective Disorders. 337, p. 75-85 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral serotonin release correlates with [11C]AZ10419369 PET measures of 5-HT1B receptor binding in the pig brain
Jørgensen, L. M., Weikop, P., Svarer, C., Feng, L., Keller, S. H. & Knudsen, Gitte Moos, 2018, In: Journal of Cerebral Blood Flow and Metabolism. 38, 7, p. 1243-1252Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral 5-HT release correlates with [C-11]Cimbi36 PET measures of 5-HT2A receptor occupancy in the pig brain
Jørgensen, L. M., Weikop, Pia, Villadsen, J., Visnapuu, T., Ettrup, A., Hansen, H. D., Baandrup, A. O., Andersen, Flemming Littrup, Bjarkam, C. R., Thomsen, C., Jespersen, B. & Knudsen, Gitte Moos, Feb 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 2, p. 425-434Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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The Bipolar Illness Onset study: research protocol for the BIO cohort study
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Design of Infusion Schemes for Neuroreceptor Imaging: Application to [(11)C]Flumazenil-PET Steady-State Study
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