Gitte Moos Knudsen

Gitte Moos Knudsen

Clinical Professor

Member of:

  • Neurology

ORCID: 0000-0003-1508-6866

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  1. Published

    Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport

    Syvanen, S., Lindhe, O., Palner, M., Kornum, Birgitte Rahbek, Rahman, O., Langstrom, B., Knudsen, Gitte Moos & Hammarlund-Udenaes, M., 2009, In: Drug Metabolism and Disposition. 37, 3, p. 635-643 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Accepted/In press

    Stable neural underpinnings of emotional cognition subgroups in patients newly diagnosed with bipolar disorder: A prospective fMRI study

    Kjærstad, H. L., de Siqueira Rotenberg, L., Macoveanu, Julian, Coello, K., Faurholt-Jepsen, Maria , Bjertrup, Anne, Knudsen, Gitte Moos, Fisher, Patrick Mac Donald, Vinberg, Maj, Kessing, Lars Vedel, Lafer, B. & Miskowiak, Kamilla, 2024, (Accepted/In press) In: Bipolar Disorders.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    State-Dependent Alterations in Inhibitory Control and Emotional Face Identification in Seasonal Affective Disorder

    Hjordt, L. V., Stenbæk, D. S., Madsen, K. S., Mc Mahon, B., Jensen, C. G., Vestergaard, M., Hageman, Ida, Meder, D., Hasselbalch, Steen & Knudsen, Gitte Moos, Apr 2017, In: Journal of Abnormal Psychology. 126, 3, p. 291-300 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Stress hormone dynamics are coupled to brain serotonin 4 receptor availability in unmedicated patients with Major Depressive Disorder - a NeuroPharm study

    Vulpius, G. M., Köhler-Forsberg, K., Ozenne, Brice Maxime Hugues, Larsen, S. V., Nasser, A., Svarer, C., Gillings, N., Keller, S. H., Jørgensen, Martin Balslev, Knudsen, Gitte Moos & Frøkjær, Vibe Gedsø, 2023, In: The international journal of neuropsychopharmacology. 26, 9, p. 639–648 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Striatal dopamine transporter binding correlates with serum BDNF levels in patients with striatal dopaminergic neurodegeneration

    Ziebell, M., Khalid, U., Klein, A. B., Aznar, S., Thomsen, G., Jensen, P., Knudsen, Gitte Moos & Jensen, P. S., 2012, In: Neurobiology of Aging. 33, 2, p. 428.e1-428.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Structural brain abnormalities associated with cognitive impairments in bipolar disorder

    Macoveanu, J., Freeman, K. O., Kjærstad, H. L., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2021, In: Acta Psychiatrica Scandinavica. 144, 4, p. 379-391 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Structural combination of established 5-HT(2A) receptor ligands: new aspects of the binding mode

    Kramer, V., Herth, Matthias Manfred, Santini, M. A., Palner, M., Knudsen, Gitte Moos & Rösch, F., 1 Oct 2010, In: Chemical Biology & Drug Design (Online). 76, 4, p. 361-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Subacute effects of a single dose of psilocybin on biomarkers of inflammation in healthy humans: An open-label preliminary investigation

    Burmester, D. R., Madsen, M. K., Szabo, A., trj450, trj450, Stenbæk, Dea Siggaard, Frøkjær, Vibe Gedsø, Elfving, B., Mikkelsen, Jens D., Knudsen, Gitte Moos & Fisher, Patrick Mac Donald, 2023, In: Comprehensive Psychoneuroendocrinology. 13, 7 p., 100163.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Sustained effects of single doses of classical psychedelics in humans

    Knudsen, Gitte Moos, 2023, In: Neuropsychopharmacology. 48, 1, p. 145-150

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Sweet taste sensitivity is influenced by 5-HTTLPR genotype and affected in seasonal affective disorder

    Andersen, S. B., Holst, K. K., McMahon, B., Madsen, M. K., Møller, P., Hageman, I. & Knudsen, Gitte Moos, Dec 2014, In: Psychiatry Research. 220, 1-2, p. 727-729 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  11. Published

    Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease

    Raval, N. R., Gudmundsen, F., Juhl, M., Andersen, Ida Vang, Speth, N., Videbæk, A., Petersen, I. N., Mikkelsen, Jens D., Fisher, P. M. D., Herth, Matthias Manfred, Plavén-Sigray, P., Knudsen, Gitte Moos & Palner, M., 2021, In: Frontiers in Synaptic Neuroscience. 13, 13 p., 715811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Synaptic density in aging mice measured by [18F]SynVesT-1 PET

    Xiong, M., Roshanbin, S., Sehlin, D., Hansen, H. D., Knudsen, Gitte Moos, Rokka, J., Eriksson, J. & Syvänen, S., 2023, In: NeuroImage. 277, 9 p., 120230.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Synthesis and Biological Evaluation of 125I/123I-Labelled Analogues of Citalopram and Escitalopram as Potential Radioligands for Imaging of the Serotonin Transporter

    Madsen, J., Elfving, B., Frøkjær, V., Kornum, B. R., Thomsen, G., Martiny, L. & Knudsen, Gitte Moos, 2011, In: Journal of Labelled Compounds and Radiopharmaceuticals. 54, p. 185-190 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Synthesis and In Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT7 Receptor Imaging with PET

    Herth, Matthias Manfred, Volk, B., Pallagi, K., Koefoed Bech, L., A. Antoni, F., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 31 Aug 2012, In: ACS Chemical Neuroscience. 3, 12, p. 1002-1007

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors

    L'Estrade, E. T., Hansen, H. D., Falk-Petersen, C., Haugaard, A., Griem-Krey, Nane, Jung, S., Lueddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, May 2019, In: ACS Omega. 4, 5, p. 8846-8851

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Synthesis and binding studies of 2-arylapomorphines

    Søndergaard, K., Kristensen, Jesper Langgaard, Palner, M., Gillings, N., Knudsen, Gitte Moos, Roth, B. & Begtrup, M., 21 Nov 2005, In: Organic & Biomolecular Chemistry. 3, 22, p. 4077-4081 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Synthesis and evaluation of [11C]Cimbi-806 as a potential PET ligand for 5-HT7 receptor imaging

    Herth, Matthias Manfred, Hansen, H. D., Ettrup, A. J., Dyssegaard, A., Lehel, S., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 2012, In: Bioorganic and Medicinal Chemistry. 20, 14, p. 4574-4581 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Synthesis and evaluation of [C-11]CIMBI-712 and [C-11]CIMBI-772

    Andersen, V. L., Herth, Matthias Manfred, Hansen, H. D., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, May 2013, p. S101-S101.

    Research output: Contribution to conference › Conference abstract for conference › Research

  19. Published

    Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET

    Herth, Matthias Manfred, Kramer, V., Piel, M., Palner, M., Riss, P. J., Knudsen, Gitte Moos & Roesch, F., 2009, In: Bioorganic & Medicinal Chemistry. 17, 8, p. 2989-3002

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Synthesis, Radiolabeling, and in Vitro and in Vivo Evaluation of [18F]ENL30: A Potential PET Radiotracer for the 5-HT7 Receptor

    Tampio L'Estrade, E., Edgar, F. G., Xiong, M., Shalgunov, Vladimir, Baerentzen, S. L., Erlandsson, M., Ohlsson, T. G., Palner, M., Knudsen, Gitte Moos & Herth, Matthias Manfred, 23 Apr 2019, In: ACS Omega. 4, 4, p. 7344-7353

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2A receptor agonists [18 F]Cimbi-92 and [18 F]Cimbi-150

    Edgar, F. G., Hansen, H. D., Leth-Petersen, S., Ettrup, A., Kristensen, Jesper Langgaard, Knudsen, Gitte Moos & Herth, Matthias Manfred, Oct 2017, In: Journal of Labelled Compounds and Radiopharmaceuticals. 60, 12, p. 586-591 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Systemic DNA and RNA damage from oxidation after serotonergic treatment of unipolar depression

    Jørgensen, Anders, Köhler-Forsberg, K., Henriksen, T., Weimann, A., Brandslund, I., Ellervik, Christina, Poulsen, Henrik Enghusen, Knudsen, Gitte Moos, Frøkjær, Vibe Gedsø & Jørgensen, Martin Balslev, 2022, In: Translational Psychiatry. 12, 8 p., 204.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Systemic catechol-O-methyl transferase inhibition enables the D1 agonist radiotracer R-[11C]SKF 82957

    Palner, M., McCormick, P., Parkes, J., Knudsen, Gitte Moos & Wilson, A. A., 1 Oct 2010, In: Nuclear Medicine and Biology. 37, 7, p. 837-43 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Testing for radioligand sensitivity to endogenous neurotransmitter release

    Knudsen, Gitte Moos, 2009, In: European Journal of Nuclear Medicine and Molecular Imaging. 36, 3, p. 472-4 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Testosterone levels in healthy men correlate negatively with serotonin 4 receptor binding

    Perfalk, E., Cunha-Bang, S. D., Holst, K. K., Keller, S., Svarer, C., Knudsen, Gitte Moos & Frokjaer, V. G., Jul 2017, In: Psychoneuroendocrinology. 81, p. 22-28 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Text mining of electronic health records can validate a register-based diagnosis of epilepsy and subgroup into focal and generalized epilepsy

    Vulpius, S. A., Werge, S., Jørgensen, Isabella Friis, Siggaard, T., Hernansanz Biel, J., Knudsen, Gitte Moos, Brunak, Søren & Pinborg, Lars Hageman, 2024, In: Epilepsia. 64, 10, p. 2750-2760 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The (18)F-fluorodeoxyglucose lumped constant determined in human brain from extraction fractions of (18)F-fluorodeoxyglucose and glucose

    Hasselbalch, Steen, Holm, S., Pedersen, H. S., Svarer, C., Knudsen, Gitte Moos, Madsen, P. L. & Paulson, Olaf B., Aug 2001, In: Journal of Cerebral Blood Flow and Metabolism. 21, 8, p. 995-1002 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The 5-HT1A serotonin receptor is located on calbindin- and parvalbumin-containing neurons in the rat brain

    Aznar, S., Qian, Z., Shah, R., Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 3 Jan 2003, In: Brain Research. 959, 1, p. 58-67 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The 5-HT2A receptor binding pattern in the human brain is strongly genetically determined

    Pinborg, Lars Hageman, Arfan, H., Haugbol, S., Kyvik, K. O., Hjelmborg, J. V. B., Svarer, C., Frokjaer, V. G., Paulson, Olaf B., Holm, S. & Knudsen, Gitte Moos, 2007, In: NeuroImage. 40, 3, p. 1175-1180 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier

    Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The BDNF Val66Met polymorphism: relation to familiar risk of affective disorder, BDNF levels and salivary cortisol

    Vinberg, Maj, Trajkovska, V., Bennike, B., Knorr, Ulla Benedichte Søsted, Knudsen, Gitte Moos, Kessing, Lars Vedel, Vinberg, Maj, Trajkovska, V., Bennike, B., Knorr, Ulla Benedichte Søsted, Knudsen, G. M. & Kessing, Lars Vedel, 2009, In: Psychoneuroendocrinology. 34, 9, p. 1380-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The Bipolar Illness Onset study: research protocol for the BIO cohort study

    Kessing, Lars Vedel, Munkholm, K., Faurholt-Jepsen, M., Miskowiak, Kamilla, Nielsen, L. B., Frikke-Schmidt, Ruth, Ekstrøm, Claus Thorn, Winther, Ole, Pedersen, Bente Klarlund, Poulsen, Henrik Enghusen, McIntyre, R. S., Kapczinski, F., Gattaz, W. F., Bardram, J., Frost, M., Mayora, O., Knudsen, Gitte Moos, Phillips, M. & Vinberg, Maj, 2017, In: BMJ Open. 7, 6, 12 p., e015462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The Impact of Hormonal Contraceptive Use on Serotonergic Neurotransmission and Antidepressant Treatment Response: Results From the NeuroPharm 1 Study

    Larsen, S. V., Ozenne, Brice Maxime Hugues, Kohler-Forsberg, K., Poulsen, A. S., Dam, Vibeke Høyrup, Svarer, C., Knudsen, Gitte Moos, Jørgensen, Martin Balslev & Frøkjær, Vibe Gedsø, 2022, In: Frontiers in Endocrinology. 13, 12 p., 799675.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The Impact of Preprocessing Pipeline Choice in Univariate and Multivariate Analyses of PET Data

    Nørgaard, M., Greve, D. N., Svarer, C., Strother, S. C., Knudsen, Gitte Moos & Ganz, Melanie, 2018, 2018 International Workshop on Pattern Recognition in Neuroimaging, PRNI 2018. IEEE, 4 p. 8423962

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  35. Published

    The Modulatory Role of Serotonin on Human Impulsive Aggression

    da Cunha-Bang, S. & Knudsen, Gitte Moos, 2021, In: Biological Psychiatry. 90, 7, p. 447-457 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  36. Published

    The Reduction of Baseline Serotonin 2A Receptors in Mild Cognitive Impairment is Stable at Two-year Follow-up

    Marner, Lisbeth, Knudsen, Gitte Moos, Madsen, K., Holm, S., Baaré, W., Hasselbalch, Steen & Holm, S., 1 Jan 2011, In: Journal of Alzheimer's Disease. 23, 3, p. 453-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The association between brain serotonin transporter binding and impulsivity and aggression in healthy individuals

    Da Cunha-bang, S., Frøkjær, Vibe Gedsø, Mc Mahon, B., Jensen, P. S., Svarer, C. & Knudsen, Gitte Moos, 2023, In: Journal of Psychiatric Research. 165, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The braindrugs-epilepsy cohort - precision medicine in the treatment of epilepsy

    Marstrand-Joergensen, M. R., Dam, V. N. H., Vinter, K., Andersen, N. B., Ip, C. T., Høi-Hansen, Christina Engel, Born, A. P., Ozenne, Brice Maxime Hugues, Ganz, Melanie, Jørgensen, Martin Balslev, Hansen, Adam Espe, Beniczky, S., Frøkjær, Vibe Gedsø, Fisher, P. M., Ryvlin, P., Knudsen, Gitte Moos & Pinborg, Lars Hageman, 2021, In: European Neuropsychopharmacology. 53, p. S39-S40 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  39. Published

    The effect of S. pneumoniae bacteremia on cerebral blood flow autoregulation in rats

    Pedersen, M., Brandt, C. T., Knudsen, Gitte Moos, Østergaard, C., Skinhøj, P., Skovsted, I. C., Frimodt-Møller, N. & Møller, Kirsten, 2008, In: Journal of Cerebral Blood Flow and Metabolism. 28, 1, p. 126-134 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The effect of storage conditions on salivary cortisol concentrations using an enzyme immunoassay

    Nalla, A. A., Thomsen, G., Knudsen, Gitte Moos & Frokjaer, V. G., 2015, In: Scandinavian Journal of Clinical & Laboratory Investigation. 75, 1, p. 92-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The effect of the inter-phase delay interval in the spontaneous object recognition test for pigs

    Kornum, Birgitte Rahbek, Thygesen, K. S., Nielsen, Thomas Rune, Knudsen, Gitte Moos & Lind, N. M., 6 Aug 2007, In: Behavioural Brain Research. 181, 2, p. 210-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions

    Johansen, A., Hansen, H. D., Svarer, C., Lehel, S., Leth-Petersen, S., Kristensen, Jesper Langgaard, Gillings, N. & Knudsen, Gitte Moos, Apr 2018, In: Journal of Cerebral Blood Flow and Metabolism. 38, 4, p. 659-668

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The longitudinal trajectory of emotion regulation and associated neural activity in patients with bipolar disorder: A prospective fMRI study

    Kjærstad, H. L., de Siqueira Rotenberg, L., Knudsen, Gitte Moos, Vinberg, Maj, Kessing, Lars Vedel, Macoveanu, J., Lafer, B. & Miskowiak, Kamilla, 2022, In: Acta Psychiatrica Scandinavica. 146, 6, p. 568-582

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The personality trait openness is related to cerebral 5-HTT levels

    Kalbitzer, J., Frokjaer, V. G., Erritzoe, D., Svarer, C., Cumming, P., Nielsen, F. A., Hashemi, S. H., Baaré, W. F. C., Madsen, J., Hasselbalch, S. G., Kringelbach, M. L., Mortensen, Erik Lykke & Knudsen, Gitte Moos, 2009, In: NeuroImage. 45, 2, p. 280-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The serotonin transporter in psychiatric disorders: insights from PET imaging

    Spies, M., Knudsen, Gitte Moos, Lanzenberger, R. & Kasper, S., Aug 2015, In: The Lancet Psychiatry. 2, 8, p. 743-55 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    The structure of the serotonin system: a PET imaging study

    Beliveau, V., Ozenne, Brice Maxime Hugues, Strother, S., Greve, D. N., Svarer, C., Knudsen, Gitte Moos & Ganz, Melanie, 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, p. 614-615 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  47. Published

    The structure of the serotonin system: A PET imaging study

    Beliveau, V., Ozenne, Brice Maxime Hugues, Strother, S., Greve, D. N., Svarer, C., Knudsen, Gitte Moos & Ganz, Melanie, 2020, In: NeuroImage. 205, 116240.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The therapeutic potential of psychedelics: the European regulatory perspective

    Butlen-Ducuing, F., McCulloch, D. E. W., Haberkamp, M., Mattila, T., Bałkowiec-Iskra, E., Aislaitner, G., Balabanov, P., Lundberg, J., Stenbæk, Dea Siggaard, Elferink, A., Knudsen, Gitte Moos & Thirstrup, Steffen, 2023, In: The Lancet. 401, 10378, p. 714-716 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  49. Published

    The variability of translocator protein signal in brain and blood of genotyped healthy humans using in vivo 123I-CLINDE SPECT imaging: A test-retest study

    Feng, L., Jensen, P., Thomsen, G., Dyssegaard, A., Svarer, C., Knudsen, L. V., Møller, Kirsten, Thomsen, C., Mikkelsen, Jens D., Guilloteau, D., Knudsen, Gitte Moos & Pinborg, Lars Hageman, 2017, In: Journal of Nuclear Medicine. 58, 6, p. 989-995 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Three weeks of SSRI administration enhances the visual perceptual threshold: a randomized placebo-controlled study

    Lansner, Jon, Jensen, C. G., Petersen, Anders, Fisher, Patrick Mac Donald, Frøkjær, Vibe Gedsø, Vangkilde, Signe & Knudsen, Gitte Moos, 2019, In: Psychopharmacology. 236, 6, p. 1759–1769

    Research output: Contribution to journal › Journal article › Research › peer-review

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