Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura
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Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura. / Hansen, Jakob Møller; Hauge, Anne Werner; Olesen, J.; Ashina, Messoud; Olesen, Jes.
In: Cephalalgia, Vol. 30, No. 10, 2010, p. 1179-86.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura
AU - Hansen, Jakob Møller
AU - Hauge, Anne Werner
AU - Olesen, J.
AU - Ashina, Messoud
AU - Olesen, Jes
PY - 2010
Y1 - 2010
N2 - Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP infusion triggers delayed migraine-like attacks in patients with migraine without aura (MO). In contrast to patients with MO, in prior studies patients with familial hemiplegic migraine (FHM) did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine in patients with typical (non-hemiplegic) migraine with aura is (MA) unknown. In the present study we examined the migraine inducing effect of CGRP infusion in patients suffering from MA and healthy controls.
AB - Calcitonin gene-related peptide (CGRP) is a key molecule in migraine pathogenesis. Intravenous CGRP infusion triggers delayed migraine-like attacks in patients with migraine without aura (MO). In contrast to patients with MO, in prior studies patients with familial hemiplegic migraine (FHM) did not report more migraine-like attacks compared to controls. Whether CGRP triggers migraine in patients with typical (non-hemiplegic) migraine with aura is (MA) unknown. In the present study we examined the migraine inducing effect of CGRP infusion in patients suffering from MA and healthy controls.
U2 - http://dx.doi.org/10.1177/0333102410368444
DO - http://dx.doi.org/10.1177/0333102410368444
M3 - Journal article
VL - 30
SP - 1179
EP - 1186
JO - Cephalalgia
JF - Cephalalgia
SN - 0800-1952
IS - 10
ER -
ID: 34083613