Torben Lykke Sørensen

Torben Lykke Sørensen

Clinical Professor, Senior Research Consultant

Member of:

  • Ophthalmology

ORCID: 0000-0002-6790-0199

Publication year:
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1 - 50 out of 173Page size: 50
  1. 2024
  2. E-pub ahead of print

    Real-world experiences with intravitreal treatment with ranibizumab and aflibercept for diabetic macular oedema 2008-2021

    Lindboe, J. B., Brynskov, T., Sørensen, Torben Lykke & Schmidt Laugesen, C., 25 Mar 2024, (E-pub ahead of print) In: Acta Ophthalmologica.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. E-pub ahead of print

    Microperimetry and Structural Risk Factors on Optical Coherence Tomography in Intermediate Age-Related Macular Degeneration

    Thomsen, Alexander Kai, Gøttsche, L. F., Hinnerskov, J. M., Falk, Mads Krüger & Sørensen, Torben Lykke, 3 Mar 2024, (E-pub ahead of print) In: Ophthalmology Retina.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. E-pub ahead of print

    TENAYA and LUCERNE: 2-Year Results from the Phase 3 nAMD Trials of Faricimab with Treat-and-Extend Dosing in Year 2

    TENAYA and LUCERNE Investigators, T. A. L. I. & Sørensen, Torben Lykke, 19 Feb 2024, (E-pub ahead of print) In: Ophthalmology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Chemokine Receptor Profile of T Cells and Progression Rate of Geographic Atrophy Secondary to Age-related Macular Degeneration

    Martinez Villarruel Hinnerskov, J., Krogh Nielsen, M., Thomsen, Alexander Kai, Steffensen, Maria Abildgaard, Honoré, B., Vorum, H., Nissen, Mogens Holst & Sørensen, Torben Lykke, 2 Jan 2024, In: Investigative Ophthalmology & Visual Science (Online). 65, 1, p. 5

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Exudative Progression of Treatment-Naïve Nonexudative Macular Neovascularization in Age-Related Macular Degeneration: A Systematic Review With Meta-Analyses

    Nissen, A. H. K., Kiilgaard, H. C., van Dijk, E. H. C., Hajari, Javad Nouri, Huemer, J., Iovino, C., Schneider, M., Sørensen, Torben Lykke, Grauslund, J. & Subhi, Y., 2024, In: American Journal of Ophthalmology. 257, p. 46-56

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Impact of COVID-19 restrictions on the treatment of neovascular age-related macular degeneration

    Bagi Nordsten, C., Rasmussen, B. K., Li, Xiaoqiang, Thomsen, Alexander Kai & Sørensen, Torben Lykke, 2024, In: Acta Ophthalmologica. 102, 3, p. e404-e405 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  8. Published

    Interleukin-8 Promoter Polymorphism -251 A/T and Treatment Response in Neovascular Age-related Macular Degeneration

    Thomsen, Alexander Kai, Krogh Nielsen, M., Liisborg, C. & Sørensen, Torben Lykke, 2024, In: Clinical ophthalmology (Auckland, N.Z.). 18, p. 537-543 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Lifestyle and demographic associations with 47 inflammatory and vascular stress biomarkers in 9876 blood donors

    Kjerulff, B., Dowsett, J., Jacobsen, R. L., Gladov, J., Larsen, M. H., Lundgaard, A. T., Banasik, K., Westergaard, D., Mikkelsen, S., Dinh, K. M., Hindhede, L., Kaspersen, K. A., Schwinn, M., Juul, A., Poulsen, B., Lindegaard, B., Pedersen, C. B., Sabel, C. E., Bundgaard, H., Nielsen, H. S. & 30 others, Møller, J. A., Boldsen, J. K., Burgdorf, Kristoffer Sølvsten, Kessing, Lars Vedel, Handgaard, L. J., Thørner, L. W., Didriksen, Maria, Nyegaard, Mette, Grarup, Niels, Ødum, Niels, Johansson, P. I., Jennum, Poul, Frikke-Schmidt, Ruth, Berger, S. S., Brunak, Søren, Jacobsen, Søren, Hansen, Thomas Folkmann, Lundquist, T. K., Hansen, Torben, Sørensen, Torben Lykke, Sigsgaard, T., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Ullum, H., Rostgaard, K., Sørensen, E., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye & Erikstrup, C., 2024, In: Communications Medicine. 4, 15 p., 50.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Neuroretinal degeneration in a mouse model of systemic chronic immune activation observed by proteomics

    Khan, A. M., Steffensen, Maria Abildgaard, Paskeviciute, E., Abduljabar, A. B., Sørensen, Torben Lykke, Vorum, H., Nissen, Mogens Holst & Honoré, B., 2024, In: Frontiers in Immunology. 15, 15 p., 1374617.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration

    Roubeix, C., Nous, C., Augustin, S., Ronning, K. E., Mathis, T., Blond, F., Lagouge-Roussey, P., Crespo-Garcia, S., Sullivan, P. M., Gautier, E. L., Reichhart, N., Sahel, J., Burns, M. E., Paques, M., Sørensen, Torben Lykke, Strauss, O., Guillonneau, X., Delarasse, C. & Sennlaub, F., 2024, In: Journal of Neuroinflammation. 21, 1, 17 p., 22.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    VEGF Inhibition Associates With Decreased Risk of Mortality in Patients With Neovascular Age-related Macular Degeneration

    Thinggaard, B. S., Frederiksen, K., Subhi, Y., Møller, S., Sørensen, Torben Lykke, Kawasaki, R., Grauslund, J. & Stokholm, L., 2024, In: Ophthalmology Science. 4, 3, 7 p., 100446.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2023
  14. Published

    Complement factor H Y402H polymorphism results in diminishing CD4+T cells and increasing C-reactive protein in plasma.

    Nielsen, M. K., Subhi, Y., Falk, Mads Krüger, Singh, Amardeep, Sørensen, Torben Lykke, Nissen, Mogens Holst & Faber, Carsten, 8 Nov 2023, In: Scientific Reports. 13, 1, 9 p., 19414.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Aldersrelateret maculadegeneration

    Bek, T. & Sørensen, Torben Lykke, Nov 2023, In: Ugeskrift for Laeger. 185, 7 p., V05230316.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Serum levels of IL-4, IL-13 and IL-33 in patients with age-related macular degeneration and myeloproliferative neoplasms

    Gotfredsen, K., Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 11 Mar 2023, In: Scientific Reports. 13, 1, p. 4077 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Association between structural and functional treatment outcomes in neovascular age-related macular degeneration

    Haji, H., Gianniou, Christina, Brynskov, T., Sørensen, Torben Lykke, Olsen, R. & Krogh Nielsen, M., 2023, In: Acta Ophthalmologica. 101, 2, p. 177-184

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Efficacy and safety of brolucizumab in age-related macular degeneration: A systematic review of real-world studies

    Baumal, C. R., Sørensen, Torben Lykke, Karcher, H., Freitas, R. L., Becher, A., Balez, S., Clemens, A., Singer, M. & Kodjikian, L., 2023, In: Acta Ophthalmologica. 101, 2, p. 123-139

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Geographic atrophy - Signs, symptoms, and quality of life

    Krogh Nielsen, M., Hinnerskov, J. M. V. & Sørensen, Torben Lykke, 2023, In: Acta Ophthalmologica. 101, 8, p. 896-902 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Heart-Rate Variability Correlates to Choroidal Thickness in Central Serous Chorioretinopathy

    Nordsten, C., Rue Molbech, C., Mehlsen, J. & Sørensen, Torben Lykke, 2023, In: Clinical Ophthalmology. 2023, 17, p. 2443—2447

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Patient perspectives and barriers in the treatment of neovascular age-related macular degeneration in Denmark: a qualitative study

    Thinggaard, B. S., Pedersen, M., Sørensen, Torben Lykke, Grauslund, J. & Stokholm, L., 2023, In: BMJ Open. 13, 11, 10 p., e077175.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Predictive value of retinal oximetry, optical coherence tomography angiography and microperimetry in patients with treatment-naïve branch retinal vein occlusion

    Frederiksen, K. H., Pedersen, F. N., Vergmann, A. S., Yang, D., Laugesen, C. S., Vestergaard, J. P., Sørensen, Torben Lykke, Cheung, C. Y., Kawasaki, R., Peto, T. & Grauslund, J., 2023, In: International journal of retina and vitreous. 9, p. 38

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Prevalence of geographic atrophy in Nordic countries and number of patients potentially eligible for intravitreal complement inhibitor treatment: A systematic review with meta-analyses and forecasting study

    Vangsted, A., Thinggaard, B. S., Nissen, A. H. K., Hajari, Javad Nouri, Klefter, Oliver Niels, Nielsen, M. K., Sørensen, Torben Lykke, Grauslund, J. & Subhi, Y., 2023, In: Acta Ophthalmologica. 101, 8, p. 857-868

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Systemic virus infection results in CD8 T cell recruitment to the retina in the absence of local virus infection

    Paskeviciute, E., Chen, M., Xu, H., Honoré, B., Vorum, H., Sørensen, Torben Lykke, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Nissen, Mogens Holst & Steffensen, Maria Abildgaard, 2023, In: Frontiers in Immunology. 14, 1221511.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Undervisning i klima og sundhed bliver en del af medicinstudiet fra 2024

    Sørensen, Torben Lykke & Kurtzhals, Jørgen, 2023, In: Ugeskrift for Laeger. 185, 4, p. 361 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  26. Published

    Use of optical coherence tomography angiography for the diagnosis of age-related macular degeneration

    Taha, A. A., Lazar, D., Julin, C. & Sørensen, Torben Lykke, 2023, In: Danish Medical Journal. 70, 10, 8 p., A12220780.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Vision-related quality of life is selectively affected by comorbidities in patients with geographic atrophy

    Holm, D. L., Nielsen, M. K., Højsted, B. B. & Sørensen, Torben Lykke, 2023, In: BMC Ophthalmology. 23, 8 p., 153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2022
  29. Published

    Retinal telangiectasia-like lesions in a 15-year-old female with Hereditary hemorrhagic telangiectasia - a case report

    Ala, A., Sørensen, Torben Lykke & Laugesen, C., 8 Nov 2022, In: BMC Ophthalmology. 22, 425.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers

    Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, Jun 2022, In: PLoS ONE. 17, 6, 16 p., e0269960.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Detection of oedema on optical coherence tomography images using deep learning model trained on noisy clinical data

    Potapenko, I., Kristensen, M., Thiesson, B., Ilginis, T., Sørensen, Torben Lykke, Nouri Hajari, J., Fuchs, J., Hamann, Steffen & la Cour, Morten, 2022, In: Acta Ophthalmologica. 100, 1, p. 103-110 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials

    Heier, J. S., Khanani, A. M., Quezada Ruiz, C., Basu, K., Ferrone, P. J., Brittain, C., Figueroa, M. S., Lin, H., Holz, F. G., Patel, V., Lai, T. Y. Y., Silverman, D., Regillo, C., Swaminathan, B., Viola, F., Cheung, C. M. G., Wong, T. Y., Abbey, A., Abdulaeva, E., Abraham, P. & 31 others, Adan Civera, A., Agostini, H., Alezzandrini, A., Alfaro, V., Almony, A., Altay, L., Amini, P., Antoszyk, A., Aradi, E., Arias, L., Arnold, J., Asaria, R., Astakhov, S., Astakhov, Y., Awh, C. C., Balaratnasingam, C., Banerjee, S., Baumal, C., Becker, M., Belfort, R., Bratko, G., Bridges, W. Z., Brown, J., Brown, D. M., Budzinskaya, M., Buffet, S., Burgess, S., Byon, I., Larsen, M., Sørensen, Torben Lykke & TENAYA and LUCERNE Investigators, T. A. L. I., 2022, In: Lancet. 399, 10326, p. 729-740 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Full-field Electroretinography Changes Associated with Age-related Macular Degeneration: A Systematic Review with Meta-Analyses

    Forshaw, T. R. J., Subhi, Y., Andréasson, S. & Sørensen, Torben Lykke, 2022, In: Ophthalmologica. 245, 3, p. 195–203

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Navigated laser and aflibercept in treatment of branch retinal vein occlusion and macular edema: a 12 months randomized clinical trial

    Frederiksen, K. H., Vestergaard, J., Pedersen, F. N., Vergmann, A. S., Sørensen, Torben Lykke, Laugesen, C., Kawasaki, R., Peto, T. & Grauslund, J., 2022, In: Investigative Ophthalmology & Visual Science. 63, 7, p. 1728 F0188.

    Research output: Contribution to journal › Conference abstract in journal › Research

  35. Published

    Navigated laser and aflibercept versus aflibercept monotherapy in treatment-naïve branch retinal vein occlusion: A 12-month randomized trial

    Frederiksen, K. H., Vestergaard, J. P., Pedersen, F. N., Vergmann, A. S., Sørensen, Torben Lykke, Laugesen, C. S., Kawasaki, R., Peto, T. & Grauslund, J., 2022, In: Acta Ophthalmologica. 100, 7, p. e1503-e1509

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Patients with MPNs and retinal drusen show signs of complement system dysregulation and a high degree of chronic low-grade inflammation

    Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2022, In: EClinicalMedicine. 43, 101248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Towards a wearable multi-modal seizure detection system in epilepsy: A pilot study

    Munch Nielsen, J., Zibrandtsen, I. C., Masulli, P., Sørensen, Torben Lykke, Andersen, T. S. & Wesenberg Kjær, T., 2022, In: Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control. 136, p. 40-48 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2021
  39. Published

    Association between C‐reactive protein and polypoidal choroidal vasculopathy: a systematic review and meta‐analysis

    Borgersen, N., Møller-Lorentzen, T., Sørensen, Torben Lykke & Subhi, Y., 2021, In: Acta Ophthalmologica. 99, 5, p. 470-477

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Correlation of macular sensitivity measures and visual acuity to vision-related quality of life in patients with age-related macular degeneration

    Forshaw, T. R. J., Parpounas, A. K. & Sørensen, Torben Lykke, 2021, In: BMC Ophthalmology. 21, 149.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Driving vision in patients with neovascular AMD in anti-VEGF treatment

    Herløv Baselius, N. J., Brynskov, T., Falk, Mads Krüger, Sørensen, Torben Lykke & Subhi, Y., 2021, In: Acta Ophthalmologica. 99, 8, p. e1360-e1365

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

    Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Full-field electroretinography in age-related macular degeneration: an overall retinal response

    Forshaw, T. R. J., Kjaer, T. W., Andréasson, S. & Sørensen, Torben Lykke, 2021, In: Acta Ophthalmologica. 99, 2, p. e253-e259

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Reasons for late diagnosis of neovascular age-related macular degeneration: a mixed-methods study

    Wahl, A. M., Musaeus, K. D., Sørensen, Torben Lykke & Kristiansen, Maria, 2021, In: Acta Ophthalmologica. 99, 3, p. e443-e445 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Retinal drusen in patients with chronic myeloproliferative blood cancers are associated with an increased proportion of senescent T cells and signs of an aging immune system

    Liisborg, C., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2021, In: Aging. 13, 24, p. 25763—25777

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Similar real-world two-year visual acuity gains in treatment-naive patients with diabetic macular oedema treated with a loading dose of three initial monthly injections versus less intensive regimens of intravitreal anti-vascular endothelial growth factor

    Lindboe, J. B., Schmidt Laugesen, C., Sørensen, Torben Lykke & Brynskov, T., 2021, In: Acta Ophthalmologica. 99, 7, p. 1248-e1249

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  47. 2020
  48. Published

    Distribution of risk alleles in patients with age-related macular degeneration

    Krogh Nielsen, M., Subhi, Y., Rue Molbech, C., Grønskov, K. & Sørensen, Torben Lykke, 1 Mar 2020, In: Danish Medical Journal. 67, 3, 6 p., A05190295.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Age-related macular degeneration: A two-level model hypothesis

    Rozing, Maarten Pieter, Durhuus, J. A., Krogh Nielsen, M., Subhi, Y., Kirkwood, T. B. L., Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2020, In: Progress in Retinal and Eye Research. 76, 100825.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Chemokine Profile and the Alterations in CCR5-CCL5 Axis in Geographic Atrophy Secondary to Age-Related Macular Degeneration

    Krogh Nielsen, M., Subhi, Y., Molbech, C. R., Falk, Mads Krüger, Nissen, Mogens Holst & Sørensen, Torben Lykke, 2020, In: Investigative Ophthalmology & Visual Science. 61, 4, 7 p., 28.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Full-field Electroretinography in Age-related Macular Degeneration: can retinal electrophysiology predict the subjective visual outcome of cataract surgery?

    Forshaw, T. R. J., Ahmed, H. J., Kjaer, T. W., Andréasson, S. & Sørensen, Torben Lykke, 2020, In: Acta Ophthalmologica. 98, 7, p. 693-700

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Myeloproliferative blood cancers as a human neuroinflammation model for development of Alzheimer's disease: evidences and perspectives

    Hasselbalch, Hans Carl, Skov, V., Kjær, L., Sørensen, Torben Lykke, Ellervik, Christina & Wienecke, Troels, 2020, In: Journal of Neuroinflammation. 17, 13 p., 248.

    Research output: Contribution to journal › Review › Research › peer-review

  53. Published

    Ocular Manifestations in Patients with Philadelphia-Negative Myeloproliferative Neoplasms

    Liisborg, C., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2020, In: Cancers. 12, 3, 14 p., 573.

    Research output: Contribution to journal › Review › Research › peer-review

  54. Published

    Patients with myeloproliferative neoplasms and high levels of systemic inflammation develop age-related macular degeneration

    Liisborg, C., Krogh Nielsen, M., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2020, In: EClinicalMedicine. 26, 8 p., 100526.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Patofysiologisk forståelse og terapeutiske muligheder ved hæmning af okulær karvækst: Pathological and therapeutic possibilities in inhibiting ocular angionesis

    Subhi, Y., Cehofski, L. J., Vestergaard, A. H., Sørensen, Torben Lykke & Grauslund, J., 2020, In: Ugeskrift for Laeger. 182, 21, 8 p., V03200178.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 20664635